HK1042701A1 - 具有hiv整合酶抑制活性的芳族雜環化合物 - Google Patents
具有hiv整合酶抑制活性的芳族雜環化合物Info
- Publication number
- HK1042701A1 HK1042701A1 HK02104241.7A HK02104241A HK1042701A1 HK 1042701 A1 HK1042701 A1 HK 1042701A1 HK 02104241 A HK02104241 A HK 02104241A HK 1042701 A1 HK1042701 A1 HK 1042701A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- aromatic heterocycle
- hiv integrase
- inhibiting activities
- heterocycle compounds
- integrase inhibiting
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP37127098 | 1998-12-25 | ||
| JP24747999 | 1999-09-01 | ||
| PCT/JP1999/007101 WO2000039086A1 (fr) | 1998-12-25 | 1999-12-17 | Composes heterocycliques aromatiques possedant des activites inhibitrices de l'integrase du vih |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1042701A1 true HK1042701A1 (zh) | 2002-08-23 |
Family
ID=26538287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK02104241.7A HK1042701A1 (zh) | 1998-12-25 | 2002-06-04 | 具有hiv整合酶抑制活性的芳族雜環化合物 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US6620841B1 (zh) |
| EP (1) | EP1142872B1 (zh) |
| JP (1) | JP3929244B2 (zh) |
| KR (1) | KR20010089708A (zh) |
| CN (1) | CN1178913C (zh) |
| AP (1) | AP2001002169A0 (zh) |
| AT (1) | ATE411286T1 (zh) |
| AU (1) | AU763040B2 (zh) |
| BR (1) | BR9916583A (zh) |
| CA (1) | CA2353961A1 (zh) |
| CZ (1) | CZ20012160A3 (zh) |
| DE (1) | DE69939749D1 (zh) |
| HK (1) | HK1042701A1 (zh) |
| HU (1) | HUP0201472A3 (zh) |
| ID (1) | ID29027A (zh) |
| IL (1) | IL143958A0 (zh) |
| NO (1) | NO20013179L (zh) |
| NZ (1) | NZ512184A (zh) |
| PL (1) | PL348596A1 (zh) |
| RU (1) | RU2225860C2 (zh) |
| TR (1) | TR200101886T2 (zh) |
| WO (1) | WO2000039086A1 (zh) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6262055B1 (en) | 1998-06-03 | 2001-07-17 | Merck & Co., Inc. | HIV integrase inhibitors |
| US6380249B1 (en) | 1998-06-03 | 2002-04-30 | Merck & Co., Inc. | HIV integrase inhibitors |
| US6306891B1 (en) | 1998-06-03 | 2001-10-23 | Merck & Co., Inc. | HIV integrase inhibitors |
| WO2000006529A1 (en) | 1998-07-27 | 2000-02-10 | Istituto Di Ricerche Di Biologia Molecolare P Angeletti S.P.A. | Diketoacid-derivatives as inhibitors of polymerases |
| GB9816358D0 (en) * | 1998-07-27 | 1998-09-23 | Angeletti P Ist Richerche Bio | Enzyme inhibitors |
| BR0011246A (pt) * | 1999-06-02 | 2002-03-05 | Shionogi & Co | Processos para o preparo de novos derivados de propenona substituìda |
| JP2003503386A (ja) * | 1999-06-25 | 2003-01-28 | メルク エンド カムパニー インコーポレーテッド | １−（芳香族またはヘテロ芳香族置換）−３−（ヘテロ芳香族置換）−１，３−プロパンジオン類およびそれの使用 |
| KR20030019423A (ko) * | 2000-06-13 | 2003-03-06 | 시오노기세이야쿠가부시키가이샤 | 프로페논 유도체를 함유하는 의약 조성물 |
| AU2001262732A1 (en) * | 2000-06-14 | 2001-12-24 | Shionogi And Co., Ltd. | Inhibitor for enzyme having two divalent metal ions as active centers |
| AU2002212701A1 (en) * | 2000-11-09 | 2002-05-21 | Shionogi And Co., Ltd. | Drug-tolerant hiv integrases |
| ATE530520T1 (de) | 2001-08-10 | 2011-11-15 | Shionogi & Co | Antivirales mittel |
| EA007060B1 (ru) * | 2001-10-26 | 2006-06-30 | Иституто Ди Ричерке Ди Биолоджиа Молеколаре П. Анджелетти Спа | N-замещённые гидроксипиримидинон-карбоксамидные ингибиторы вич интегразы |
| TW200407132A (en) * | 2001-11-15 | 2004-05-16 | Shionogi & Co | Process for producing 1-H-1,2,4-triazole-3-carboxylic acid ester |
| WO2003047564A1 (fr) * | 2001-12-05 | 2003-06-12 | Shionogi & Co., Ltd. | Dérivé ayant une activité d'inhibition de l'intégrase du vih |
| US7358249B2 (en) | 2002-08-13 | 2008-04-15 | Shionogi & Co., Ltd. | Heterocyclic compounds having inhibitory activity against HIV integrase |
| US20040157804A1 (en) | 2002-10-16 | 2004-08-12 | Gilead Sciences, Inc. | Pre-organized tricyclic integrase inhibitor compounds |
| CN1569803B (zh) * | 2003-07-16 | 2011-04-13 | 中国科学院上海药物研究所 | 芳基β－二酮酸的新制备方法 |
| JP2007529422A (ja) * | 2004-01-29 | 2007-10-25 | エリクシアー ファーマシューティカルズ， インコーポレイテッド | 抗ウイルス治療 |
| MX2007002236A (es) * | 2004-08-25 | 2007-07-09 | Ardea Biosciences Inc | S-triazolil-alfa-mercaptoacetanilidas como inhibidores de transcriptasa inversa de virus de inmunodeficiencia humana. |
| JP4953297B2 (ja) * | 2004-09-15 | 2012-06-13 | 塩野義製薬株式会社 | Ｈｉｖインテグラーゼ阻害活性を有するカルバモイルピリドン誘導体 |
| AU2005311714B2 (en) * | 2004-12-03 | 2010-09-30 | Merck Sharp & Dohme Corp. | Pharmaceutical composition containing an anti-nucleating agent |
| UA87884C2 (uk) * | 2004-12-03 | 2009-08-25 | Мерк Энд Ко., Инк. | Безводна кристалічна калієва сіль інгібітора віл-інтегрази |
| US7250421B2 (en) * | 2005-01-31 | 2007-07-31 | University Of Georgia Research Foundation, Inc. | Diketo acids with nucleobase scaffolds: anti-HIV replication inhibitors targeted at HIV integrase |
| US20080280849A1 (en) * | 2005-06-01 | 2008-11-13 | Herve Leh | Synergic Combinations Comprising a Quinoline Compound and Other Hiv Infection Therapeutic Agents |
| AU2007254190A1 (en) * | 2006-05-16 | 2007-11-29 | Gilead Sciences, Inc. | Integrase inhibitors |
| US7888375B2 (en) | 2006-07-19 | 2011-02-15 | The University Of Georgia Research Foundation, Inc | Pyridinone diketo acids: inhibitors of HIV replication |
| WO2008041882A1 (fr) * | 2006-10-03 | 2008-04-10 | Viktor Veniaminovich Tets | Procédé pour agir sur les virus au moyen d'une substance à base de 2,8-dithioxo-1h- pyrano[2,3-d;6,5-d'] dipyrimidine et de leurs analogues 10-aza (et variantes) |
| EP2254582B1 (en) | 2008-01-25 | 2016-01-20 | Chimerix, Inc. | Methods of treating viral infections |
| US8664255B2 (en) | 2008-10-20 | 2014-03-04 | The Texas A&M University System | Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof |
| EP2509949B1 (en) | 2009-12-07 | 2014-04-23 | University Of Georgia Research Foundation, Inc. | Pyridinone hydroxycyclopentyl carboxamides: hiv integrase inhibitors with therapeutic applications |
| US9006218B2 (en) | 2010-02-12 | 2015-04-14 | Chimerix Inc. | Nucleoside phosphonate salts |
| CA2793959C (en) | 2010-03-25 | 2019-06-04 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| CN101928258B (zh) * | 2010-08-18 | 2014-10-29 | 杭州民生药业有限公司 | 1-(2-取代苯胺基-4-甲基-噻唑-5)-3-取代苯基-丙烯酮衍生物、制备方法及其制药用途 |
| HUE037408T2 (hu) | 2011-06-10 | 2018-08-28 | Univ Oregon Health & Science | CMV glikoproteinek és rekombináns vektorok |
| WO2014026033A1 (en) | 2012-08-08 | 2014-02-13 | University Of Florida Research Foundation, Inc. | Cross-reactive t cell epitopes of hiv, siv, and fiv for vaccines in humans and cats |
| DK3067358T3 (da) | 2012-12-21 | 2019-11-04 | Gilead Sciences Inc | Polycykliske carbamoylpyridon-forbindelser og deres farmaceutiske anvendelse |
| PT3019503T (pt) | 2013-07-12 | 2017-11-27 | Gilead Sciences Inc | Compostos carbamoílpiridona- policíclicos e seu uso para o tratamento de infecções por hiv |
| NO2865735T3 (zh) | 2013-07-12 | 2018-07-21 | ||
| TW201613936A (en) | 2014-06-20 | 2016-04-16 | Gilead Sciences Inc | Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide |
| TWI744723B (zh) | 2014-06-20 | 2021-11-01 | 美商基利科學股份有限公司 | 多環型胺甲醯基吡啶酮化合物之合成 |
| NO2717902T3 (zh) | 2014-06-20 | 2018-06-23 | ||
| TWI738321B (zh) | 2014-12-23 | 2021-09-01 | 美商基利科學股份有限公司 | 多環胺甲醯基吡啶酮化合物及其醫藥用途 |
| KR20190057158A (ko) | 2015-04-02 | 2019-05-27 | 길리애드 사이언시즈, 인코포레이티드 | 폴리시클릭-카르바모일피리돈 화합물 및 그의 제약 용도 |
| CN106905244B (zh) * | 2017-02-27 | 2019-08-16 | 武汉工程大学 | 二芳基嘧啶-二酮酸类杂合型hiv-1抑制剂及其制备方法 |
| US20230032101A1 (en) * | 2019-10-28 | 2023-02-02 | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences | Five-membered heterocyclic oxocarboxylic acid compound and medical use thereof |
| CN111943899B (zh) * | 2020-09-08 | 2023-04-21 | 河北凯诺中星科技有限公司 | 一种5-甲酸乙酯四氮唑的合成方法 |
| CN113683574B (zh) * | 2021-09-06 | 2023-11-17 | 上海晋鲁医药科技有限公司 | 一种合成1-甲基-1h-1,2,4-三唑-3-甲酸甲酯的方法 |
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|---|---|---|---|---|
| US3899508A (en) | 1974-04-12 | 1975-08-12 | Lilly Co Eli | 5-(2-Aminophenyl)pyrazole-3-carboxylic acids and esters thereof |
| US3931247A (en) * | 1974-12-11 | 1976-01-06 | Morton-Norwich Products, Inc. | 5-(Substituted)phenylfurfuryl alcohols |
| JPS5811878B2 (ja) * | 1974-12-19 | 1983-03-04 | 大正製薬株式会社 | フロ （ ３ ２−ｂ ） インド−ルルイノ セイホウ |
| JPS56100784A (en) | 1980-01-16 | 1981-08-12 | Yoshitomi Pharmaceut Ind Ltd | Indolizine derivative |
| US4273776A (en) * | 1980-01-30 | 1981-06-16 | E. R. Squibb & Sons, Inc. | Antibacterial and antifungal derivatives of 3-(1H-imidazol-1-yl)-2-propen-1-ones |
| US4336397A (en) | 1980-12-29 | 1982-06-22 | Merck & Co., Inc. | 2,4-Dioxo-4-substituted-1-butanoic acid derivatives useful in treating urinary tract calcium oxalate lithiasis |
| US4423063A (en) | 1980-12-29 | 1983-12-27 | Merck & Co., Inc. | 2,4-Dioxo-4-substituted-1-butaoic acid derivatives useful in treating urinary track calcium oxalate lithiasis |
| US4332735A (en) * | 1981-07-06 | 1982-06-01 | Morton-Norwich Products, Inc. | Antifungal compound |
| US4637829A (en) * | 1984-04-27 | 1987-01-20 | Ciba-Geigy Corporation | Sulfonylureas |
| JPS61134346A (ja) | 1984-12-03 | 1986-06-21 | Shionogi & Co Ltd | ４−オキソカルボン酸誘導体および抗潰瘍剤 |
| CA1334975C (en) * | 1987-11-13 | 1995-03-28 | James H. Holms | Furan and pyrrole containing lipoxygenase inhibiting compounds |
| JPH0238403A (ja) | 1988-07-28 | 1990-02-07 | Canon Inc | 光重合性組成物および記録媒体 |
| PH27357A (en) | 1989-09-22 | 1993-06-21 | Fujisawa Pharmaceutical Co | Pyrazole derivatives and pharmaceutical compositions comprising the same |
| US5192773A (en) * | 1990-07-02 | 1993-03-09 | Vertex Pharmaceuticals, Inc. | Immunosuppressive compounds |
| TW224974B (zh) * | 1991-07-02 | 1994-06-11 | Hoffmann La Roche | |
| EP0658559A1 (de) * | 1993-12-14 | 1995-06-21 | Chemisch Pharmazeutische Forschungsgesellschaft m.b.H. | Thienothiazinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als 5-dipoxygenase und Cyclooxygenaseinhibitoren |
| US5475109A (en) | 1994-10-17 | 1995-12-12 | Merck & Co., Inc. | Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease |
| US5693804A (en) * | 1994-11-17 | 1997-12-02 | Molecular Geriatrics Corporation | Substituted 1-aryl-3-piperazin-1'-yl propanones |
| YU49899A (sh) | 1997-04-04 | 2002-09-19 | Pfizer Products Inc. | Nikotinamidni derivati |
| IL122591A0 (en) | 1997-12-14 | 1998-06-15 | Arad Dorit | Pharmaceutical compositions comprising cystein protease inhibitors |
| JP3794469B2 (ja) | 1998-03-26 | 2006-07-05 | 塩野義製薬株式会社 | 抗ウイルス作用を有するインドール誘導体 |
| WO1999048371A1 (en) | 1998-03-27 | 1999-09-30 | The Regents Of The University Of California | Novel hiv integrase inhibitors and hiv therapy based on drug combinations including integrase inhibitors |
| WO1999062520A1 (en) | 1998-06-03 | 1999-12-09 | Merck & Co., Inc. | Hiv integrase inhibitors |
| CA2329134A1 (en) | 1998-06-03 | 1999-12-09 | David L. Clark | Hiv integrase inhibitors |
| EP1086091A4 (en) | 1998-06-03 | 2001-10-10 | Merck & Co Inc | HIV INTEGRASE INHIBITORS |
| JP2003503386A (ja) | 1999-06-25 | 2003-01-28 | メルク エンド カムパニー インコーポレーテッド | １−（芳香族またはヘテロ芳香族置換）−３−（ヘテロ芳香族置換）−１，３−プロパンジオン類およびそれの使用 |
-
1999
- 1999-12-17 AP APAP/P/2001/002169A patent/AP2001002169A0/en unknown
- 1999-12-17 EP EP99961299A patent/EP1142872B1/en not_active Expired - Lifetime
- 1999-12-17 DE DE69939749T patent/DE69939749D1/de not_active Expired - Lifetime
- 1999-12-17 JP JP2000590998A patent/JP3929244B2/ja not_active Expired - Fee Related
- 1999-12-17 BR BR9916583-0A patent/BR9916583A/pt not_active IP Right Cessation
- 1999-12-17 IL IL14395899A patent/IL143958A0/xx unknown
- 1999-12-17 KR KR1020017008150A patent/KR20010089708A/ko not_active Application Discontinuation
- 1999-12-17 TR TR2001/01886T patent/TR200101886T2/xx unknown
- 1999-12-17 AT AT99961299T patent/ATE411286T1/de not_active IP Right Cessation
- 1999-12-17 NZ NZ512184A patent/NZ512184A/xx unknown
- 1999-12-17 CZ CZ20012160A patent/CZ20012160A3/cs unknown
- 1999-12-17 RU RU2001120016/04A patent/RU2225860C2/ru not_active IP Right Cessation
- 1999-12-17 CN CNB99816285XA patent/CN1178913C/zh not_active Expired - Fee Related
- 1999-12-17 PL PL99348596A patent/PL348596A1/xx not_active Application Discontinuation
- 1999-12-17 WO PCT/JP1999/007101 patent/WO2000039086A1/ja not_active Application Discontinuation
- 1999-12-17 AU AU17979/00A patent/AU763040B2/en not_active Ceased
- 1999-12-17 ID IDW00200101355A patent/ID29027A/id unknown
- 1999-12-17 CA CA002353961A patent/CA2353961A1/en not_active Abandoned
- 1999-12-17 US US09/857,632 patent/US6620841B1/en not_active Expired - Fee Related
- 1999-12-17 HU HU0201472A patent/HUP0201472A3/hu unknown
-
2001
- 2001-06-22 NO NO20013179A patent/NO20013179L/no not_active Application Discontinuation
-
2002
- 2002-06-04 HK HK02104241.7A patent/HK1042701A1/zh unknown
- 2002-11-06 US US10/288,380 patent/US6645956B1/en not_active Expired - Fee Related
-
2003
- 2003-06-18 US US10/463,816 patent/US7098201B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1142872A4 (en) | 2002-04-17 |
| US6620841B1 (en) | 2003-09-16 |
| HUP0201472A3 (en) | 2006-03-28 |
| RU2225860C2 (ru) | 2004-03-20 |
| NZ512184A (en) | 2003-08-29 |
| AU763040B2 (en) | 2003-07-10 |
| EP1142872A1 (en) | 2001-10-10 |
| WO2000039086A1 (fr) | 2000-07-06 |
| ID29027A (id) | 2001-07-26 |
| DE69939749D1 (de) | 2008-11-27 |
| ATE411286T1 (de) | 2008-10-15 |
| US20040002485A1 (en) | 2004-01-01 |
| AP2001002169A0 (en) | 2001-06-30 |
| CA2353961A1 (en) | 2000-07-06 |
| BR9916583A (pt) | 2001-09-25 |
| IL143958A0 (en) | 2002-04-21 |
| CN1178913C (zh) | 2004-12-08 |
| RU2001120016A (ru) | 2003-12-10 |
| HUP0201472A2 (hu) | 2003-10-28 |
| JP3929244B2 (ja) | 2007-06-13 |
| US6645956B1 (en) | 2003-11-11 |
| KR20010089708A (ko) | 2001-10-08 |
| CN1335834A (zh) | 2002-02-13 |
| CZ20012160A3 (cs) | 2001-10-17 |
| NO20013179L (no) | 2001-08-27 |
| PL348596A1 (en) | 2002-06-03 |
| US7098201B2 (en) | 2006-08-29 |
| TR200101886T2 (tr) | 2001-12-21 |
| AU1797900A (en) | 2000-07-31 |
| NO20013179D0 (no) | 2001-06-22 |
| EP1142872B1 (en) | 2008-10-15 |
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