WO2003047564A1 - Dérivé ayant une activité d'inhibition de l'intégrase du vih - Google Patents
Dérivé ayant une activité d'inhibition de l'intégrase du vih Download PDFInfo
- Publication number
- WO2003047564A1 WO2003047564A1 PCT/JP2002/012582 JP0212582W WO03047564A1 WO 2003047564 A1 WO2003047564 A1 WO 2003047564A1 JP 0212582 W JP0212582 W JP 0212582W WO 03047564 A1 WO03047564 A1 WO 03047564A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- inhibitory activity
- derivative
- ring
- integrase inhibitory
- hiv integrase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003548820A JP4497347B2 (ja) | 2001-12-05 | 2002-12-02 | Hivインテグラーゼ阻害活性を有する誘導体 |
AU2002349675A AU2002349675A1 (en) | 2001-12-05 | 2002-12-02 | Derivative having hiv integrase inhibitory activity |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001-371436 | 2001-12-05 | ||
JP2001371436 | 2001-12-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003047564A1 true WO2003047564A1 (fr) | 2003-06-12 |
Family
ID=19180478
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/012582 WO2003047564A1 (fr) | 2001-12-05 | 2002-12-02 | Dérivé ayant une activité d'inhibition de l'intégrase du vih |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP4497347B2 (fr) |
AU (1) | AU2002349675A1 (fr) |
WO (1) | WO2003047564A1 (fr) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6953858B2 (en) | 2001-06-11 | 2005-10-11 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis |
US7001912B2 (en) | 2003-01-27 | 2006-02-21 | Agouron Pharmaceuticals, Inc. | HIV-integrase inhibitors, pharmaceutical compositions, and methods for their use |
US7094909B2 (en) | 2001-06-11 | 2006-08-22 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis |
JP2006342115A (ja) * | 2005-06-10 | 2006-12-21 | Shionogi & Co Ltd | Hivインテグラーゼ阻害活性を有する多環性化合物 |
US7169932B2 (en) | 2001-06-11 | 2007-01-30 | Pfizer Inc. | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses, material for their synthesis |
US7211572B2 (en) | 2003-08-13 | 2007-05-01 | Japan Tobacco Inc. | Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor |
US7217713B2 (en) | 2001-10-26 | 2007-05-15 | Istituto Di Richerche Di Biologia Molecolare P. Angeletti S.P.A. | N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase |
WO2008004100A2 (fr) | 2006-07-05 | 2008-01-10 | Pfizer Products Inc. | Composés thérapeutiques |
US7368571B2 (en) | 2002-10-31 | 2008-05-06 | Pfizer Inc | HIV-Integrase inhibitors, pharmaceutical compositions and methods for their use |
US7468375B2 (en) | 2004-04-26 | 2008-12-23 | Pfizer Inc. | Inhibitors of the HIV integrase enzyme |
US7692014B2 (en) | 2004-04-26 | 2010-04-06 | Pfizer, Inc. | Inhibitors of the HIV integrase enzyme |
WO2011076765A1 (fr) | 2009-12-23 | 2011-06-30 | Katholieke Universiteit Leuven | Nouveaux composés antiviraux |
WO2012066442A1 (fr) | 2010-11-15 | 2012-05-24 | Pfizer Limited | Inhibiteurs de la réplication du vih |
WO2012065963A2 (fr) | 2010-11-15 | 2012-05-24 | Katholieke Universiteit Leuven | Nouveaux composés antiviraux |
WO2013091089A1 (fr) * | 2011-12-22 | 2013-06-27 | UNIVERSITé LAVAL | Cavités tridimensionnelles d'immunorécepteur de cellules dendritiques (dcir), composés se liant à celles-ci et applications thérapeutiques associées à l'inhibition du virus de l'immunodéficience humaine de type 1 (vih-1) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000039086A1 (fr) * | 1998-12-25 | 2000-07-06 | Shionogi & Co., Ltd. | Composes heterocycliques aromatiques possedant des activites inhibitrices de l'integrase du vih |
WO2001017968A1 (fr) * | 1999-09-02 | 2001-03-15 | Shionogi & Co., Ltd. | Inhibiteur d'integrase contenant des derives heterocycliques aromatiques |
WO2001095905A1 (fr) * | 2000-06-14 | 2001-12-20 | Shionogi & Co., Ltd. | Inhibiteur d'enzymes possedant deux ions metal divalents en tant que centres actifs |
WO2002036734A2 (fr) * | 2000-10-12 | 2002-05-10 | Merck & Co., Inc. | Aza- et polyaza-naphtalenyl cetones utiles en tant qu'inhibiteurs de l'integrase du vih |
WO2002070491A1 (fr) * | 2001-03-01 | 2002-09-12 | Shionogi & Co., Ltd. | Derive a noyau heteroaromatique azote presentant une activite d'inhibiteur d'integrase du vih |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
WO1992021641A1 (fr) * | 1991-05-29 | 1992-12-10 | Pfizer Inc. | Composes de dihydrozyindanone inhibiteurs des tyrosine kinases |
-
2002
- 2002-12-02 WO PCT/JP2002/012582 patent/WO2003047564A1/fr active Application Filing
- 2002-12-02 AU AU2002349675A patent/AU2002349675A1/en not_active Abandoned
- 2002-12-02 JP JP2003548820A patent/JP4497347B2/ja not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000039086A1 (fr) * | 1998-12-25 | 2000-07-06 | Shionogi & Co., Ltd. | Composes heterocycliques aromatiques possedant des activites inhibitrices de l'integrase du vih |
WO2001017968A1 (fr) * | 1999-09-02 | 2001-03-15 | Shionogi & Co., Ltd. | Inhibiteur d'integrase contenant des derives heterocycliques aromatiques |
WO2001095905A1 (fr) * | 2000-06-14 | 2001-12-20 | Shionogi & Co., Ltd. | Inhibiteur d'enzymes possedant deux ions metal divalents en tant que centres actifs |
WO2002036734A2 (fr) * | 2000-10-12 | 2002-05-10 | Merck & Co., Inc. | Aza- et polyaza-naphtalenyl cetones utiles en tant qu'inhibiteurs de l'integrase du vih |
WO2002070491A1 (fr) * | 2001-03-01 | 2002-09-12 | Shionogi & Co., Ltd. | Derive a noyau heteroaromatique azote presentant une activite d'inhibiteur d'integrase du vih |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7179918B2 (en) | 2001-06-11 | 2007-02-20 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis |
US7094909B2 (en) | 2001-06-11 | 2006-08-22 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis |
US6953858B2 (en) | 2001-06-11 | 2005-10-11 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis |
US7169932B2 (en) | 2001-06-11 | 2007-01-30 | Pfizer Inc. | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses, material for their synthesis |
US7435734B2 (en) | 2001-10-26 | 2008-10-14 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase |
US7217713B2 (en) | 2001-10-26 | 2007-05-15 | Istituto Di Richerche Di Biologia Molecolare P. Angeletti S.P.A. | N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase |
US7368571B2 (en) | 2002-10-31 | 2008-05-06 | Pfizer Inc | HIV-Integrase inhibitors, pharmaceutical compositions and methods for their use |
US7138408B2 (en) | 2003-01-27 | 2006-11-21 | Agouron Pharmaceuticals, Inc. | HIV integrase inhibitors, pharmaceutical compositions and methods for their use |
US7001912B2 (en) | 2003-01-27 | 2006-02-21 | Agouron Pharmaceuticals, Inc. | HIV-integrase inhibitors, pharmaceutical compositions, and methods for their use |
EP2042502A1 (fr) | 2003-08-13 | 2009-04-01 | Japan Tobacco Inc. | Composé cyclique fondu contenant de l'azote et son utilisation en tant qu'inhibiteur de l'intégrase du VIH |
US7211572B2 (en) | 2003-08-13 | 2007-05-01 | Japan Tobacco Inc. | Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor |
US7468375B2 (en) | 2004-04-26 | 2008-12-23 | Pfizer Inc. | Inhibitors of the HIV integrase enzyme |
US7692014B2 (en) | 2004-04-26 | 2010-04-06 | Pfizer, Inc. | Inhibitors of the HIV integrase enzyme |
JP2006342115A (ja) * | 2005-06-10 | 2006-12-21 | Shionogi & Co Ltd | Hivインテグラーゼ阻害活性を有する多環性化合物 |
WO2008004100A2 (fr) | 2006-07-05 | 2008-01-10 | Pfizer Products Inc. | Composés thérapeutiques |
WO2011076765A1 (fr) | 2009-12-23 | 2011-06-30 | Katholieke Universiteit Leuven | Nouveaux composés antiviraux |
WO2012066442A1 (fr) | 2010-11-15 | 2012-05-24 | Pfizer Limited | Inhibiteurs de la réplication du vih |
WO2012065963A2 (fr) | 2010-11-15 | 2012-05-24 | Katholieke Universiteit Leuven | Nouveaux composés antiviraux |
WO2013091089A1 (fr) * | 2011-12-22 | 2013-06-27 | UNIVERSITé LAVAL | Cavités tridimensionnelles d'immunorécepteur de cellules dendritiques (dcir), composés se liant à celles-ci et applications thérapeutiques associées à l'inhibition du virus de l'immunodéficience humaine de type 1 (vih-1) |
US9731001B2 (en) | 2011-12-22 | 2017-08-15 | Universite Laval | Three-dimensional cavities of dendritic cell immunoreceptor (DCIR), compounds binding thereto and therapeutic applications related to inhibition of human immunodeficiency virus type-1 (HIV-1) |
Also Published As
Publication number | Publication date |
---|---|
JP4497347B2 (ja) | 2010-07-07 |
JPWO2003047564A1 (ja) | 2005-04-14 |
AU2002349675A1 (en) | 2003-06-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2003016275A1 (fr) | Agent antiviral | |
WO2003047564A1 (fr) | Dérivé ayant une activité d'inhibition de l'intégrase du vih | |
WO2002004444A3 (fr) | Carboxamides heterocycliques utilises comme agents antiviraux | |
WO2002004443A3 (fr) | Carboxamides heterocycliques utilises comme agents antiviraux | |
WO2003037864A1 (fr) | Compose indolique, et utilisation a des fins therapeutiques | |
WO2002026697A3 (fr) | Derives aromatiques a proprietes inhibitrices d'integrase de vih | |
WO2008120759A1 (fr) | Composé d'urée et son utilisation | |
WO2004058679A3 (fr) | Ligands d'adenine nucleotide translocase (ant) et compositions et methodes associees | |
WO2001072728A3 (fr) | Nouveaux derives de piperazine | |
EP1736465A4 (fr) | Dérivés d'aniline | |
AU2003212282A1 (en) | Cdk inhibiting 2-heteroaryl pyrimidine, the production thereof, and use thereof as a medicament | |
AU2001262318A1 (en) | Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament | |
CA2368675A1 (fr) | Prophylaxies/remedes pour la pneumonie interstitielle et la fibrose pulmonaire | |
AU763636C (en) | 1-cycloalkyl-1,8-naphthyridin-4-one derivatives with phosphodiesterase IV inhibitory activity | |
WO2001047928A3 (fr) | Nouveaux imidazo[1,3,5]triazinones et leur utilisation | |
MY134880A (en) | Thiazolyl amide derivatives | |
WO2002070491A1 (fr) | Derive a noyau heteroaromatique azote presentant une activite d'inhibiteur d'integrase du vih | |
WO2002085291A3 (fr) | Analogues de la nociceptine | |
WO2003082881A3 (fr) | Derives du pyridoxal-5-phosphate en tant qu'inhibiteurs de l'integrase du vih | |
WO1998027930A3 (fr) | Nouvelle utilisation des derives d'aminopiperazine | |
WO2007018941A3 (fr) | Composes | |
WO2000046210A3 (fr) | Nouveau procede de preparation d'intermediaires pesticides | |
WO2001025239A3 (fr) | Oxazinoquinolones utiles pour le traitement d'infections virales | |
AU2003243765A1 (en) | 2,4-disubstituted-pyridine n-oxides useful as hiv reverse transcriptase inhibitors | |
WO2000059862A3 (fr) | Procedes destines a la preparation de produits intermediaires pesticides |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2003548820 Country of ref document: JP |
|
122 | Ep: pct application non-entry in european phase |