HK1039146B - 使用多孔硅將物質轉入細胞 - Google Patents
使用多孔硅將物質轉入細胞Info
- Publication number
- HK1039146B HK1039146B HK02100735.8A HK02100735A HK1039146B HK 1039146 B HK1039146 B HK 1039146B HK 02100735 A HK02100735 A HK 02100735A HK 1039146 B HK1039146 B HK 1039146B
- Authority
- HK
- Hong Kong
- Prior art keywords
- cells
- porous silicon
- cell
- vehicle
- transferring materials
- Prior art date
Links
- 239000000463 material Substances 0.000 title abstract 4
- 229910021426 porous silicon Inorganic materials 0.000 title abstract 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 229910021420 polycrystalline silicon Inorganic materials 0.000 abstract 1
- 229910052710 silicon Inorganic materials 0.000 abstract 1
- 239000010703 silicon Substances 0.000 abstract 1
- 239000011856 silicon-based particle Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/89—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/89—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
- C12N15/895—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection using biolistic methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Sustainable Development (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Silicon Compounds (AREA)
- Electrotherapy Devices (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Battery Electrode And Active Subsutance (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9815819.9A GB9815819D0 (en) | 1998-07-22 | 1998-07-22 | Transferring materials into cells and a microneedle array |
PCT/GB1999/002383 WO2000005339A1 (en) | 1998-07-22 | 1999-07-22 | Transferring materials into cells using porous silicon |
Publications (2)
Publication Number | Publication Date |
---|---|
HK1039146A1 HK1039146A1 (en) | 2002-04-12 |
HK1039146B true HK1039146B (zh) | 2006-10-27 |
Family
ID=10835869
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02100735.8A HK1039146B (zh) | 1998-07-22 | 2002-01-30 | 使用多孔硅將物質轉入細胞 |
Country Status (15)
Country | Link |
---|---|
US (2) | US6770480B1 (zh) |
EP (3) | EP1098957B1 (zh) |
JP (1) | JP4585119B2 (zh) |
KR (1) | KR100633273B1 (zh) |
CN (1) | CN1252275C (zh) |
AT (1) | ATE223479T1 (zh) |
AU (1) | AU753542B2 (zh) |
CA (1) | CA2337331C (zh) |
DE (1) | DE69902794T2 (zh) |
DK (1) | DK1098957T3 (zh) |
ES (2) | ES2400472T3 (zh) |
GB (1) | GB9815819D0 (zh) |
HK (1) | HK1039146B (zh) |
NZ (1) | NZ509142A (zh) |
WO (1) | WO2000005339A1 (zh) |
Families Citing this family (123)
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GB0008494D0 (en) * | 2000-04-07 | 2000-05-24 | Secr Defence | Microprojectile delivery system |
GB2363115A (en) * | 2000-06-10 | 2001-12-12 | Secr Defence | Porous or polycrystalline silicon orthopaedic implants |
US6533949B1 (en) * | 2000-08-28 | 2003-03-18 | Nanopass Ltd. | Microneedle structure and production method therefor |
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-
1998
- 1998-07-22 GB GBGB9815819.9A patent/GB9815819D0/en not_active Ceased
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1999
- 1999-07-22 DE DE69902794T patent/DE69902794T2/de not_active Expired - Lifetime
- 1999-07-22 EP EP99934933A patent/EP1098957B1/en not_active Expired - Lifetime
- 1999-07-22 JP JP2000561286A patent/JP4585119B2/ja not_active Expired - Lifetime
- 1999-07-22 AT AT99934933T patent/ATE223479T1/de active
- 1999-07-22 US US09/743,447 patent/US6770480B1/en not_active Expired - Lifetime
- 1999-07-22 WO PCT/GB1999/002383 patent/WO2000005339A1/en active IP Right Grant
- 1999-07-22 ES ES04030257T patent/ES2400472T3/es not_active Expired - Lifetime
- 1999-07-22 ES ES99934933T patent/ES2179666T3/es not_active Expired - Lifetime
- 1999-07-22 EP EP02004895A patent/EP1231259A3/en not_active Withdrawn
- 1999-07-22 DK DK99934933T patent/DK1098957T3/da active
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- 1999-07-22 AU AU50554/99A patent/AU753542B2/en not_active Expired
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- 1999-07-22 CN CNB99809028XA patent/CN1252275C/zh not_active Expired - Lifetime
- 1999-07-22 NZ NZ509142A patent/NZ509142A/en not_active IP Right Cessation
- 1999-07-22 KR KR1020017001028A patent/KR100633273B1/ko not_active IP Right Cessation
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2002
- 2002-01-30 HK HK02100735.8A patent/HK1039146B/zh not_active IP Right Cessation
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CA2337331C (en) | 2012-08-28 |
NZ509142A (en) | 2004-01-30 |
KR100633273B1 (ko) | 2006-10-16 |
AU753542B2 (en) | 2002-10-24 |
CA2337331A1 (en) | 2000-02-03 |
ES2400472T3 (es) | 2013-04-10 |
DK1098957T3 (da) | 2003-01-06 |
US6770480B1 (en) | 2004-08-03 |
US20040220535A1 (en) | 2004-11-04 |
JP4585119B2 (ja) | 2010-11-24 |
WO2000005339A1 (en) | 2000-02-03 |
CN1310755A (zh) | 2001-08-29 |
DE69902794T2 (de) | 2003-08-07 |
EP1231259A2 (en) | 2002-08-14 |
EP1098957A1 (en) | 2001-05-16 |
AU5055499A (en) | 2000-02-14 |
KR20010072050A (ko) | 2001-07-31 |
CN1252275C (zh) | 2006-04-19 |
ES2179666T3 (es) | 2003-01-16 |
GB9815819D0 (en) | 1998-09-16 |
JP2002521024A (ja) | 2002-07-16 |
HK1039146A1 (en) | 2002-04-12 |
DE69902794D1 (de) | 2002-10-10 |
EP1231259A3 (en) | 2003-11-19 |
EP1522578B1 (en) | 2013-01-09 |
EP1522578A1 (en) | 2005-04-13 |
ATE223479T1 (de) | 2002-09-15 |
US7332339B2 (en) | 2008-02-19 |
EP1098957B1 (en) | 2002-09-04 |
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