HK1036799A1 - Benzo(b)thiepine-1, 1-dioxide derivatives, a method for the production thereof, medicaments containing these compounds, and their use - Google Patents

Benzo(b)thiepine-1, 1-dioxide derivatives, a method for the production thereof, medicaments containing these compounds, and their use

Info

Publication number
HK1036799A1
HK1036799A1 HK01107735A HK01107735A HK1036799A1 HK 1036799 A1 HK1036799 A1 HK 1036799A1 HK 01107735 A HK01107735 A HK 01107735A HK 01107735 A HK01107735 A HK 01107735A HK 1036799 A1 HK1036799 A1 HK 1036799A1
Authority
HK
Hong Kong
Prior art keywords
thiepine
benzo
compounds
production
medicaments containing
Prior art date
Application number
HK01107735A
Other languages
English (en)
Inventor
Wendelin Frick
Alfons Enhsen
Heiner Glombik
Hubert Heuer
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of HK1036799A1 publication Critical patent/HK1036799A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D337/00Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02Seven-membered rings
    • C07D337/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/04Drugs for disorders of the urinary system for urolithiasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06086Dipeptides with the first amino acid being basic
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Polymers & Plastics (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK01107735A 1998-06-10 2001-11-06 Benzo(b)thiepine-1, 1-dioxide derivatives, a method for the production thereof, medicaments containing these compounds, and their use HK1036799A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19825804A DE19825804C2 (de) 1998-06-10 1998-06-10 1,4-Benzothiepin-1,1-dioxidderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
PCT/EP1999/003701 WO1999064410A1 (de) 1998-06-10 1999-05-28 BENZO(b)THIEPIN-1,1-DIOXIDDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND DEREN VERWENDUNG

Publications (1)

Publication Number Publication Date
HK1036799A1 true HK1036799A1 (en) 2002-01-18

Family

ID=7870440

Family Applications (2)

Application Number Title Priority Date Filing Date
HK01107746A HK1039490A1 (en) 1998-06-10 2001-11-06 Benzothiepine-1,1-dioxide derivatives, method for producing them, composition containing these compounds and their use.
HK01107735A HK1036799A1 (en) 1998-06-10 2001-11-06 Benzo(b)thiepine-1, 1-dioxide derivatives, a method for the production thereof, medicaments containing these compounds, and their use

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK01107746A HK1039490A1 (en) 1998-06-10 2001-11-06 Benzothiepine-1,1-dioxide derivatives, method for producing them, composition containing these compounds and their use.

Country Status (26)

Country Link
US (1) US6387944B1 (hu)
EP (2) EP1086092B1 (hu)
JP (2) JP4374426B2 (hu)
KR (2) KR100681721B1 (hu)
CN (2) CN1127497C (hu)
AR (2) AR018634A1 (hu)
AT (2) ATE227715T1 (hu)
AU (2) AU753275B2 (hu)
BR (2) BR9912188B1 (hu)
CA (2) CA2334775C (hu)
CZ (2) CZ297989B6 (hu)
DE (3) DE19825804C2 (hu)
DK (2) DK1086092T3 (hu)
ES (2) ES2182535T3 (hu)
HK (2) HK1039490A1 (hu)
HU (2) HU229761B1 (hu)
ID (2) ID28695A (hu)
IL (1) IL140078A (hu)
NO (1) NO327075B1 (hu)
NZ (1) NZ508681A (hu)
PL (2) PL196074B1 (hu)
PT (2) PT1086092E (hu)
RU (2) RU2215001C2 (hu)
TR (2) TR200003634T2 (hu)
WO (2) WO1999064410A1 (hu)
ZA (2) ZA200007060B (hu)

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DE50212937D1 (de) * 2001-08-22 2008-12-04 Sanofi Aventis Deutschland Kombinationspräparate von 1,4- benzothiepin-1,1-dioxidderivaten mit weiteren wirkstoffen und deren verwendung
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Also Published As

Publication number Publication date
AU4503199A (en) 1999-12-30
NO20006251L (no) 2001-02-07
IL140078A0 (en) 2002-02-10
AR018633A1 (es) 2001-11-28
BR9911123B1 (pt) 2010-12-14
HK1039490A1 (en) 2002-04-26
ATE259372T1 (de) 2004-02-15
NO20006251D0 (no) 2000-12-08
KR20010052682A (ko) 2001-06-25
CA2334775A1 (en) 1999-12-16
AU4501999A (en) 1999-12-30
DE19825804A1 (de) 1999-12-16
PL196074B1 (pl) 2007-12-31
AU753275B2 (en) 2002-10-10
HUP0102256A3 (en) 2002-04-29
KR20010052701A (ko) 2001-06-25
JP2002517491A (ja) 2002-06-18
ID28695A (id) 2001-06-28
CZ297925B6 (cs) 2007-05-02
TR200003634T2 (tr) 2001-06-21
JP2002517490A (ja) 2002-06-18
BR9912188A (pt) 2001-04-10
ZA200007060B (en) 2001-07-18
KR100562184B1 (ko) 2006-03-20
PL345901A1 (en) 2002-01-14
US6387944B1 (en) 2002-05-14
CN1152039C (zh) 2004-06-02
NO327075B1 (no) 2009-04-20
DE59903411D1 (de) 2002-12-19
DK1086113T3 (da) 2004-05-24
ES2182535T3 (es) 2003-03-01
BR9912188B1 (pt) 2010-12-14
IL140078A (en) 2004-08-31
HU229761B1 (hu) 2014-06-30
PL196057B1 (pl) 2007-11-30
WO1999064409A2 (de) 1999-12-16
NZ508681A (en) 2002-06-28
DE19825804C2 (de) 2000-08-24
HUP0102256A1 (hu) 2001-12-28
CN1305469A (zh) 2001-07-25
CA2334773C (en) 2009-05-26
AR018634A1 (es) 2001-11-28
EP1086113A2 (de) 2001-03-28
DE59908522D1 (de) 2004-03-18
RU2215001C2 (ru) 2003-10-27
ZA200007061B (en) 2001-07-18
AU752633B2 (en) 2002-09-26
EP1086092A1 (de) 2001-03-28
EP1086092B1 (de) 2002-11-13
CN1127497C (zh) 2003-11-12
PT1086092E (pt) 2003-03-31
ES2215387T3 (es) 2004-10-01
EP1086113B1 (de) 2004-02-11
RU2220141C2 (ru) 2003-12-27
CZ297989B6 (cs) 2007-05-16
WO1999064409A3 (de) 2000-03-02
HUP0102554A1 (hu) 2001-10-28
KR100681721B1 (ko) 2007-02-15
PL344827A1 (en) 2001-11-19
TR200003632T2 (tr) 2001-04-20
HUP0102554A3 (en) 2002-12-28
CN1305487A (zh) 2001-07-25
JP3374129B2 (ja) 2003-02-04
CA2334773A1 (en) 1999-12-16
ID26876A (id) 2001-02-15
BR9911123A (pt) 2006-01-03
CZ20004592A3 (cs) 2001-04-11
HU228570B1 (en) 2013-04-29
DK1086092T3 (da) 2003-03-10
CZ20004591A3 (cs) 2001-04-11
ATE227715T1 (de) 2002-11-15
JP4374426B2 (ja) 2009-12-02
WO1999064410A1 (de) 1999-12-16
PT1086113E (pt) 2004-06-30
CA2334775C (en) 2009-10-13

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