HK1003114A1 - Fluorocytidine derivatives, their preparation and medical preparations containing them - Google Patents

Fluorocytidine derivatives, their preparation and medical preparations containing them Download PDF

Info

Publication number
HK1003114A1
HK1003114A1 HK98102225A HK98102225A HK1003114A1 HK 1003114 A1 HK1003114 A1 HK 1003114A1 HK 98102225 A HK98102225 A HK 98102225A HK 98102225 A HK98102225 A HK 98102225A HK 1003114 A1 HK1003114 A1 HK 1003114A1
Authority
HK
Hong Kong
Prior art keywords
deoxy
fluoro
fluorocytidine
cytidine
methylammonium
Prior art date
Application number
HK98102225A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1003114B (en
Inventor
Fujiu Morio
Ishitsuka Hideo
Miwa Masanori
Umeda Isao
Yokose Kazuteru
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of HK1003114A1 publication Critical patent/HK1003114A1/xx
Publication of HK1003114B publication Critical patent/HK1003114B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/067Pyrimidine radicals with ribosyl as the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HK98102225.6A 1987-11-17 1998-03-17 Fluorocytidine derivatives, their preparation and medical preparations containing them HK1003114B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP87116926 1987-11-17
EP87116926 1987-11-17

Publications (2)

Publication Number Publication Date
HK1003114A1 true HK1003114A1 (en) 1998-10-09
HK1003114B HK1003114B (en) 1998-10-09

Family

ID=

Also Published As

Publication number Publication date
ZA888428B (en) 1989-06-28
DE10199027I2 (de) 2002-01-31
CS274486B2 (en) 1991-04-11
DK640388A (da) 1989-05-18
NO2001013I2 (no) 2006-05-01
IS1895B (is) 2003-10-20
PT89009B (pt) 1993-02-26
NO171167C (no) 1993-02-03
DK640388D0 (da) 1988-11-16
EP0316704A3 (en) 1990-11-22
PH25641A (en) 1991-08-21
HUT48267A (en) 1989-05-29
DE10199027I1 (de) 2001-08-02
LV5624A3 (lv) 1994-05-10
MC1992A1 (fr) 1989-11-30
DK170893B1 (da) 1996-03-04
IE883430L (en) 1989-05-17
NO885106D0 (no) 1988-11-16
FI89804B (fi) 1993-08-13
NL300045I2 (nl) 2002-01-02
CN1022688C (zh) 1993-11-10
YU209188A (en) 1990-08-31
LT2185B (lt) 1993-10-15
MX13836A (es) 1993-10-01
HU199866B (en) 1990-03-28
NO885106L (no) 1989-05-18
YU47122B (sh) 1994-12-28
JPH0678350B2 (ja) 1994-10-05
AU619220B2 (en) 1992-01-23
NL300045I1 (nl) 2001-08-01
ES2074429T3 (es) 1995-09-16
KR970000241B1 (ko) 1997-01-08
KR890008162A (ko) 1989-07-10
IS3412A7 (is) 1989-05-18
NO171167B (no) 1992-10-26
MX173347B (es) 1994-01-03
EP0316704B1 (de) 1995-07-12
ATE124951T1 (de) 1995-07-15
FI885329A0 (fi) 1988-11-17
IL88363A0 (en) 1989-06-30
CA1327358C (en) 1994-03-01
AU2516888A (en) 1989-05-25
EP0316704A2 (de) 1989-05-24
DZ1270A1 (fr) 2004-09-13
NZ226923A (en) 1990-10-26
GR3017686T3 (en) 1996-01-31
SU1736342A3 (ru) 1992-05-23
AR247217A1 (es) 1994-11-30
CS747588A2 (en) 1990-09-12
JPH01153696A (ja) 1989-06-15
US4966891A (en) 1990-10-30
CN1033183A (zh) 1989-05-31
PT89009A (pt) 1988-12-01
UA19333A (uk) 1997-12-25
LU90769I2 (fr) 2001-07-02
FI89804C (fi) 1993-11-25
FI885329L (fi) 1989-05-18
DE3854148D1 (de) 1995-08-17

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PF Patent in force
PE Patent expired

Effective date: 20081106