HK1000285A1 - Arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes, their salts, medicaments containing the same, use thereof and precesses for their production - Google Patents

Arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes, their salts, medicaments containing the same, use thereof and precesses for their production Download PDF

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Publication number
HK1000285A1
HK1000285A1 HK97101852A HK97101852A HK1000285A1 HK 1000285 A1 HK1000285 A1 HK 1000285A1 HK 97101852 A HK97101852 A HK 97101852A HK 97101852 A HK97101852 A HK 97101852A HK 1000285 A1 HK1000285 A1 HK 1000285A1
Authority
HK
Hong Kong
Prior art keywords
group
denotes
denote
hydrogen atom
atom
Prior art date
Application number
HK97101852A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1000285B (en
Inventor
Maier Roland
Muller Peter
Woitun Eberhard
Hurnaus Rudolf
Mark Michael
Eisele Bernhard
Budzinski Ralph-Michael
Hallermayer Gerhard
Original Assignee
Dr Karl Thomae Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4235590A external-priority patent/DE4235590A1/de
Application filed by Dr Karl Thomae Gmbh filed Critical Dr Karl Thomae Gmbh
Publication of HK1000285B publication Critical patent/HK1000285B/xx
Publication of HK1000285A1 publication Critical patent/HK1000285A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Ink Jet (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK97101852A 1992-10-22 1997-09-26 Arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes, their salts, medicaments containing the same, use thereof and precesses for their production HK1000285A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4235590A DE4235590A1 (de) 1992-10-22 1992-10-22 Aryliden-l-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4235590 1992-10-22
DE4303840 1993-02-10
DE4303840A DE4303840A1 (de) 1992-10-22 1993-02-10 Aryliden-1-azacycloalkane und Arylalkyl-1-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung

Publications (2)

Publication Number Publication Date
HK1000285B HK1000285B (en) 1998-02-20
HK1000285A1 true HK1000285A1 (en) 1998-02-20

Family

ID=25919689

Family Applications (1)

Application Number Title Priority Date Filing Date
HK97101852A HK1000285A1 (en) 1992-10-22 1997-09-26 Arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes, their salts, medicaments containing the same, use thereof and precesses for their production

Country Status (21)

Country Link
EP (1) EP0596326B1 (cs)
JP (1) JP3396517B2 (cs)
KR (1) KR100306520B1 (cs)
CN (1) CN1040873C (cs)
AT (1) ATE126797T1 (cs)
AU (1) AU665648B2 (cs)
CA (1) CA2108817C (cs)
CZ (1) CZ286025B6 (cs)
DE (2) DE4303840A1 (cs)
DK (1) DK0596326T3 (cs)
ES (1) ES2078787T3 (cs)
FI (1) FI934665A7 (cs)
GR (1) GR3017692T3 (cs)
HK (1) HK1000285A1 (cs)
HU (1) HU221630B1 (cs)
IL (1) IL107342A (cs)
NO (1) NO300843B1 (cs)
NZ (1) NZ250018A (cs)
PL (1) PL173775B1 (cs)
RU (1) RU2126400C1 (cs)
SK (1) SK281222B6 (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4234295A1 (de) * 1992-10-12 1994-04-14 Thomae Gmbh Dr K Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
IL110943A (en) * 1994-09-13 1997-02-18 Univ Ramot Compositions comprising an inhibitor of cholesterol synthesis for the treatment of skin disorders
DE19754795A1 (de) 1997-12-10 1999-06-17 Boehringer Ingelheim Pharma Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
AU5227999A (en) * 1998-07-27 2000-02-21 Abbott Laboratories Substituted oxazolines as antiproliferative agents
US6228868B1 (en) 1998-07-27 2001-05-08 Abbott Laboratories Oxazoline antiproliferative agents
JP4459629B2 (ja) 2002-04-12 2010-04-28 メルク エンド カムパニー インコーポレーテッド 二環式アミド

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863932A (en) * 1988-03-11 1989-09-05 Somatogenetics International, Inc. Squalene oxide cyclase inhibitors and therapeutic use thereof
CA2025490C (en) * 1989-09-22 2003-09-16 James R. Mccarthy Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis
AU638852B2 (en) * 1990-07-24 1993-07-08 Merrell Dow Pharmaceuticals Inc. Novel substituted piperidines and their use as inhibitors of cholesterol synthesis
NZ239022A (en) * 1990-07-25 1993-11-25 Merrell Dow Pharma Piperidyl ethers and thioethers; preparatory processes and pharmaceutical compositions
US5084461A (en) * 1991-03-27 1992-01-28 Merrell Dow Pharmaceuticals Inc. Azadecalin amides and thioamides as inhibitors of cholesterol biosynthesis

Also Published As

Publication number Publication date
EP0596326A1 (de) 1994-05-11
HUT68958A (en) 1995-08-28
AU665648B2 (en) 1996-01-11
IL107342A (en) 1997-07-13
NO933790D0 (no) 1993-10-21
HU9302986D0 (en) 1994-01-28
JPH06192256A (ja) 1994-07-12
EP0596326B1 (de) 1995-08-23
GR3017692T3 (en) 1996-01-31
PL173775B1 (pl) 1998-04-30
DE4303840A1 (de) 1994-08-11
RU2126400C1 (ru) 1999-02-20
AU4913593A (en) 1994-05-05
CA2108817A1 (en) 1994-04-23
FI934665A0 (fi) 1993-10-22
SK107393A3 (en) 1994-09-07
FI934665L (fi) 1994-04-23
CZ223693A3 (en) 1994-05-18
ATE126797T1 (de) 1995-09-15
NZ250018A (en) 1995-07-26
CN1040873C (zh) 1998-11-25
IL107342A0 (en) 1994-01-25
DK0596326T3 (da) 1996-01-15
SK281222B6 (sk) 2001-01-18
KR100306520B1 (ko) 2001-11-30
KR940009181A (ko) 1994-05-20
JP3396517B2 (ja) 2003-04-14
HU221630B1 (hu) 2002-12-28
PL300834A1 (en) 1994-05-16
CN1090849A (zh) 1994-08-17
ES2078787T3 (es) 1995-12-16
NO300843B1 (no) 1997-08-04
FI934665A7 (fi) 1994-04-23
NO933790L (no) 1994-04-25
DE59300507D1 (de) 1995-09-28
CA2108817C (en) 2004-12-07
CZ286025B6 (cs) 1999-12-15

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)