DK0596326T3 - Aryliden-1-azacycloalkaner og arylalkyl-1-azacycloalkaner og salte deraf, lægemidler indeholdende forbindelserne og forbindelsernes anvendelse samt fremgangsmåde til fremstilling af forbindelserne - Google Patents
Aryliden-1-azacycloalkaner og arylalkyl-1-azacycloalkaner og salte deraf, lægemidler indeholdende forbindelserne og forbindelsernes anvendelse samt fremgangsmåde til fremstilling af forbindelserneInfo
- Publication number
- DK0596326T3 DK0596326T3 DK93116959.3T DK93116959T DK0596326T3 DK 0596326 T3 DK0596326 T3 DK 0596326T3 DK 93116959 T DK93116959 T DK 93116959T DK 0596326 T3 DK0596326 T3 DK 0596326T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- azacycloalkanes
- arylidene
- arylalkyl
- salts
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 3
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Ink Jet (AREA)
- Developing Agents For Electrophotography (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4235590A DE4235590A1 (de) | 1992-10-22 | 1992-10-22 | Aryliden-l-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
| DE4303840A DE4303840A1 (de) | 1992-10-22 | 1993-02-10 | Aryliden-1-azacycloalkane und Arylalkyl-1-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0596326T3 true DK0596326T3 (da) | 1996-01-15 |
Family
ID=25919689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93116959.3T DK0596326T3 (da) | 1992-10-22 | 1993-10-20 | Aryliden-1-azacycloalkaner og arylalkyl-1-azacycloalkaner og salte deraf, lægemidler indeholdende forbindelserne og forbindelsernes anvendelse samt fremgangsmåde til fremstilling af forbindelserne |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0596326B1 (cs) |
| JP (1) | JP3396517B2 (cs) |
| KR (1) | KR100306520B1 (cs) |
| CN (1) | CN1040873C (cs) |
| AT (1) | ATE126797T1 (cs) |
| AU (1) | AU665648B2 (cs) |
| CA (1) | CA2108817C (cs) |
| CZ (1) | CZ286025B6 (cs) |
| DE (2) | DE4303840A1 (cs) |
| DK (1) | DK0596326T3 (cs) |
| ES (1) | ES2078787T3 (cs) |
| FI (1) | FI934665L (cs) |
| GR (1) | GR3017692T3 (cs) |
| HK (1) | HK1000285A1 (cs) |
| HU (1) | HU221630B1 (cs) |
| IL (1) | IL107342A (cs) |
| NO (1) | NO300843B1 (cs) |
| NZ (1) | NZ250018A (cs) |
| PL (1) | PL173775B1 (cs) |
| RU (1) | RU2126400C1 (cs) |
| SK (1) | SK281222B6 (cs) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4234295A1 (de) * | 1992-10-12 | 1994-04-14 | Thomae Gmbh Dr K | Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| IL110943A (en) * | 1994-09-13 | 1997-02-18 | Univ Ramot | Compositions comprising an inhibitor of cholesterol synthesis for the treatment of skin disorders |
| DE19754795A1 (de) * | 1997-12-10 | 1999-06-17 | Boehringer Ingelheim Pharma | Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
| US6228868B1 (en) | 1998-07-27 | 2001-05-08 | Abbott Laboratories | Oxazoline antiproliferative agents |
| WO2000006556A1 (en) * | 1998-07-27 | 2000-02-10 | Abbott Laboratories | Substituted oxazolines as antiproliferative agents |
| CA2481313A1 (en) | 2002-04-12 | 2003-10-23 | Merck & Co., Inc. | Bicyclic amides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4863932A (en) * | 1988-03-11 | 1989-09-05 | Somatogenetics International, Inc. | Squalene oxide cyclase inhibitors and therapeutic use thereof |
| CA2025490C (en) * | 1989-09-22 | 2003-09-16 | James R. Mccarthy | Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis |
| ZA915660B (en) * | 1990-07-24 | 1992-05-27 | Merrell Dow Pharma | Novel substituted piperidines and their use as inhibitors of cholesterol synthesis |
| ZA915659B (en) * | 1990-07-25 | 1992-05-27 | Merrell Dow Pharma | Novel piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis |
| US5084461A (en) * | 1991-03-27 | 1992-01-28 | Merrell Dow Pharmaceuticals Inc. | Azadecalin amides and thioamides as inhibitors of cholesterol biosynthesis |
-
1993
- 1993-02-10 DE DE4303840A patent/DE4303840A1/de not_active Ceased
- 1993-10-05 SK SK1073-93A patent/SK281222B6/sk unknown
- 1993-10-20 ES ES93116959T patent/ES2078787T3/es not_active Expired - Lifetime
- 1993-10-20 DE DE59300507T patent/DE59300507D1/de not_active Expired - Lifetime
- 1993-10-20 DK DK93116959.3T patent/DK0596326T3/da active
- 1993-10-20 CA CA002108817A patent/CA2108817C/en not_active Expired - Fee Related
- 1993-10-20 EP EP93116959A patent/EP0596326B1/de not_active Expired - Lifetime
- 1993-10-20 AT AT93116959T patent/ATE126797T1/de active
- 1993-10-21 KR KR1019930021923A patent/KR100306520B1/ko not_active Expired - Fee Related
- 1993-10-21 NO NO933790A patent/NO300843B1/no not_active IP Right Cessation
- 1993-10-21 RU RU93048154/04A patent/RU2126400C1/ru not_active IP Right Cessation
- 1993-10-21 AU AU49135/93A patent/AU665648B2/en not_active Ceased
- 1993-10-21 NZ NZ250018A patent/NZ250018A/en unknown
- 1993-10-21 HU HU9302986A patent/HU221630B1/hu not_active IP Right Cessation
- 1993-10-21 JP JP26321493A patent/JP3396517B2/ja not_active Expired - Fee Related
- 1993-10-21 IL IL107342A patent/IL107342A/xx not_active IP Right Cessation
- 1993-10-22 CN CN93119156A patent/CN1040873C/zh not_active Expired - Fee Related
- 1993-10-22 PL PL93300834A patent/PL173775B1/pl unknown
- 1993-10-22 FI FI934665A patent/FI934665L/fi unknown
- 1993-10-22 CZ CZ932236A patent/CZ286025B6/cs not_active IP Right Cessation
-
1995
- 1995-10-11 GR GR950402801T patent/GR3017692T3/el unknown
-
1997
- 1997-09-26 HK HK97101852A patent/HK1000285A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0530087T3 (da) | Hidtil ukendte naphthylethylurinstof- og naphthylethylthiourinstofforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem | |
| NO302884B1 (no) | Krystallinske 3,4,4-trisubstituert-piperidinyl-N-alkylkarboksylater og mellomprodukter, fremgangsmåte for fremstilling av de krystallinske karboksylatene, farmasöytiske preparater inneholdende disse og deres anvendelse | |
| DK0659174T3 (da) | Derivater af valproinsyre og 2-valproensyreamider samt deres anvendelse som antikonvulsive midler | |
| DK0562956T3 (da) | Hidtil ukendte naphthylalkylaminer, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem | |
| AU1608692A (en) | Amidinophenylalanine derivatives, a process for the preparation thereof, use thereof and agents containing these as anticoagulants | |
| ATE269290T1 (de) | Benzoylderivate | |
| DK0612322T3 (da) | Fremgangsmåde til adskillelse af 5-methyl-tetrahydrofolsyre | |
| NO180679C (no) | Pyranylcyanoguanidin-derivater, preparater som inneholder dem og anvendelse derav | |
| DK0404283T3 (da) | 11alfa-aryl-4-estrener, fremgangsmåde til fremstilling af disse samt deres anvendelse som lægemidler | |
| DK0532515T3 (da) | Fremstilling af substituerede piperidiner | |
| NZ228065A (en) | 1,2,4-triazinediones and parasiticidal compositions; processes for preparation | |
| BR9206823A (pt) | Preparação de piperidinas substituídas | |
| DK243989A (da) | Ringsubstituerede 2-amino-1,2,3,4-tetrahydronaphthalener, fremgangsmaade til fremstilling af saadanne forbindelser og laegemidler indeholdende disse | |
| DK0596326T3 (da) | Aryliden-1-azacycloalkaner og arylalkyl-1-azacycloalkaner og salte deraf, lægemidler indeholdende forbindelserne og forbindelsernes anvendelse samt fremgangsmåde til fremstilling af forbindelserne | |
| DK0553016T3 (da) | Hidtil ukendte naphtalenamider og -sulfonamider, fremgangsmåder til deres fremstilling samt farmaceutiske midler indeholdende dem | |
| ATE113628T1 (de) | Ammonium-verbindung, diese enthaltende zusammensetzung und desinfektionsverfahren. | |
| ITMI911853A1 (it) | Sale del diclofenac, metodo di preparazione e composizioni farmaceutiche che lo contengono. | |
| IL85425A (en) | Anticonvulsant compositions containing substituted benzoyl anilides, some such novel compounds and process for their preparation | |
| DK284588D0 (da) | Beta-lactam-forbindelser, deres fremstilling og anvendelse som laegemidler. | |
| DK47988D0 (da) | Substituerede 3-phenyl-7h-thiazolooe3,2-baaoe1,2,4aatriazin-7-oner, deres fremstilling og anvendelse som laegemiddel, samt ved fremstillingen anvendelige mellemprodukter | |
| DK0410278T3 (da) | Reninhæmmende aminooligohydroxyderivater | |
| BR9100488A (pt) | Processo para a preparacao de compostos,composicao para o combate ou inibicao de uma infestacao por microorganismos | |
| DK0611755T3 (da) | Hidtil ukendte (cyklohexyl)alkenforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem | |
| DK0433978T3 (da) | Fremgangsmåde til fremstilling af nojirimycin og beslægtede forbindelser |