DK0433978T3 - Fremgangsmåde til fremstilling af nojirimycin og beslægtede forbindelser - Google Patents
Fremgangsmåde til fremstilling af nojirimycin og beslægtede forbindelserInfo
- Publication number
- DK0433978T3 DK0433978T3 DK90124580.3T DK90124580T DK0433978T3 DK 0433978 T3 DK0433978 T3 DK 0433978T3 DK 90124580 T DK90124580 T DK 90124580T DK 0433978 T3 DK0433978 T3 DK 0433978T3
- Authority
- DK
- Denmark
- Prior art keywords
- nojirimycin
- preparation
- related compounds
- reductive amination
- oxo
- Prior art date
Links
- BGMYHTUCJVZIRP-UHFFFAOYSA-N Nojirimycin Natural products OCC1NC(O)C(O)C(O)C1O BGMYHTUCJVZIRP-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- BGMYHTUCJVZIRP-GASJEMHNSA-N nojirimycin Chemical compound OC[C@H]1NC(O)[C@H](O)[C@@H](O)[C@@H]1O BGMYHTUCJVZIRP-GASJEMHNSA-N 0.000 title 1
- LXBIFEVIBLOUGU-JGWLITMVSA-N duvoglustat Chemical compound OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O LXBIFEVIBLOUGU-JGWLITMVSA-N 0.000 abstract 2
- 238000006268 reductive amination reaction Methods 0.000 abstract 2
- KLXQAXYSOJNJRI-JGWLITMVSA-N (2r,3s,4r,5r)-5-amino-2,3,4,6-tetrahydroxyhexanal Chemical compound OC[C@@H](N)[C@@H](O)[C@H](O)[C@@H](O)C=O KLXQAXYSOJNJRI-JGWLITMVSA-N 0.000 abstract 1
- 229950002441 glucurolactone Drugs 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45364789A | 1989-12-20 | 1989-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0433978T3 true DK0433978T3 (da) | 1996-05-28 |
Family
ID=23801471
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90124580.3T DK0433978T3 (da) | 1989-12-20 | 1990-12-18 | Fremgangsmåde til fremstilling af nojirimycin og beslægtede forbindelser |
Country Status (14)
Country | Link |
---|---|
US (1) | US5227479A (da) |
EP (1) | EP0433978B1 (da) |
JP (1) | JP2938193B2 (da) |
KR (1) | KR0147819B1 (da) |
AT (1) | ATE137758T1 (da) |
AU (1) | AU632191B2 (da) |
DE (1) | DE69026912T2 (da) |
DK (1) | DK0433978T3 (da) |
ES (1) | ES2088948T3 (da) |
GR (1) | GR3020492T3 (da) |
HU (1) | HU207866B (da) |
IE (1) | IE72513B1 (da) |
IL (1) | IL96694A (da) |
ZA (1) | ZA9010083B (da) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5066807A (en) * | 1990-03-12 | 1991-11-19 | Merrell Dow Pharmaceuticals Inc. | Process for the preparation of castanospermine |
KR100446483B1 (ko) | 2000-03-31 | 2004-09-01 | 미시간 스테이트 유니버시티 | 옥심 또는 이민으로부터 1,5-디데옥시-1,5-이미노 헥시톨제조방법 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4634765A (en) * | 1984-12-18 | 1987-01-06 | Merrell Dow Pharmaceuticals Inc. | Homodisaccharide hypoglycemic agents |
DE3628486A1 (de) * | 1986-08-22 | 1988-02-25 | Bayer Ag | Piperidinderivate |
US4880917A (en) * | 1988-07-01 | 1989-11-14 | Merrell Dow Pharmaceuticals Inc. | Process for hydrolyzing 2,6-dideoxy-2,6-iminoheptononitrile derivatives using trifluoroacetic acid and dinitrogen tetroxide |
US4908439A (en) * | 1988-09-16 | 1990-03-13 | Merrell Dow Pharmaceuticals Inc. | Synthesis of intermediate useful in the preparation of nojirimycin and related compounds |
-
1990
- 1990-11-14 US US07/610,690 patent/US5227479A/en not_active Expired - Fee Related
- 1990-12-14 AU AU68084/90A patent/AU632191B2/en not_active Ceased
- 1990-12-14 ZA ZA9010083A patent/ZA9010083B/xx unknown
- 1990-12-17 HU HU908300A patent/HU207866B/hu not_active IP Right Cessation
- 1990-12-17 IL IL9669490A patent/IL96694A/en not_active IP Right Cessation
- 1990-12-18 DK DK90124580.3T patent/DK0433978T3/da active
- 1990-12-18 EP EP90124580A patent/EP0433978B1/en not_active Expired - Lifetime
- 1990-12-18 DE DE69026912T patent/DE69026912T2/de not_active Expired - Fee Related
- 1990-12-18 AT AT90124580T patent/ATE137758T1/de not_active IP Right Cessation
- 1990-12-18 ES ES90124580T patent/ES2088948T3/es not_active Expired - Lifetime
- 1990-12-19 JP JP2411708A patent/JP2938193B2/ja not_active Expired - Lifetime
- 1990-12-19 IE IE459890A patent/IE72513B1/en not_active IP Right Cessation
- 1990-12-19 KR KR1019900021075A patent/KR0147819B1/ko not_active IP Right Cessation
-
1996
- 1996-07-09 GR GR960401860T patent/GR3020492T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH0418072A (ja) | 1992-01-22 |
IE904598A1 (en) | 1991-07-03 |
EP0433978A2 (en) | 1991-06-26 |
DE69026912T2 (de) | 1996-10-02 |
EP0433978A3 (en) | 1992-09-09 |
HU908300D0 (en) | 1991-06-28 |
ZA9010083B (en) | 1991-10-30 |
EP0433978B1 (en) | 1996-05-08 |
IL96694A (en) | 1994-12-29 |
US5227479A (en) | 1993-07-13 |
DE69026912D1 (de) | 1996-06-13 |
AU6808490A (en) | 1991-06-27 |
ES2088948T3 (es) | 1996-10-01 |
IE72513B1 (en) | 1997-04-23 |
AU632191B2 (en) | 1992-12-17 |
IL96694A0 (en) | 1991-09-16 |
KR910011882A (ko) | 1991-08-07 |
HU207866B (en) | 1993-06-28 |
HUT57224A (en) | 1991-11-28 |
KR0147819B1 (ko) | 1998-08-01 |
JP2938193B2 (ja) | 1999-08-23 |
GR3020492T3 (en) | 1996-10-31 |
ATE137758T1 (de) | 1996-05-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0657428T3 (da) | Fremstilling af 3,4,4-trisubstituerede-piperidinyl-N-alkylcarboxylater og mellemprodukter, der er egnede som opioidantagonister | |
TW218869B (da) | ||
FI870113A0 (fi) | Menetelmä uusien terapeuttisesti käyttökelpoisten 4,5,6-substioitujenN-(substituoitu-fenyyli)-2-pyrimidiiniamiinien valmistamiseksi | |
ATE188460T1 (de) | Verfahren zum herstellen von derivaten des 4a,5,9,10,11,12,-hexahydro-6h-benzofuro(3a,3,2- ef)(2)benzazepins | |
KR960702830A (ko) | 방사선 보호제로서의 N-알킬티오 폴리아민 유도체(N-Alkylthio polyaine derivatives as radioprotective agents) | |
MY107819A (en) | Preparation of substituted piperidines. | |
NZ228065A (en) | 1,2,4-triazinediones and parasiticidal compositions; processes for preparation | |
DK546489D0 (da) | Thienopyridin-mevalonolactoner, fremgangsmaade til fremstilling heraf og farmaceutisk praeparat omfattende samme | |
DK303588D0 (da) | Fremgangsmaade til forbedret nitrogenudnyttelse ved hjaelp af glutaminsynthetaseoverproduktion | |
AU5263690A (en) | Ammonium compound, composition containing it and desinfection method | |
DK0433978T3 (da) | Fremgangsmåde til fremstilling af nojirimycin og beslægtede forbindelser | |
ATE205203T1 (de) | D4t polymorphe form i verfahren | |
GR1001309B (el) | Μεθοδος παρασκευης παραγωγου ενωσεως της διχλωροανιλινης. | |
DK0596326T3 (da) | Aryliden-1-azacycloalkaner og arylalkyl-1-azacycloalkaner og salte deraf, lægemidler indeholdende forbindelserne og forbindelsernes anvendelse samt fremgangsmåde til fremstilling af forbindelserne | |
EP0232027A3 (en) | N-carboxyalkyl compounds | |
HK54891A (en) | Hexahydropyrrolo(2,1-a)isoquinoline derivatives | |
DK0431305T3 (da) | Fremgangsmåde til fremstilling af molluskicide 2,4,5-tribrompyrrol-3-carbonitriler | |
ES8800204A1 (es) | Un procedimiento para la preparacion de piridazinilimidazolidinonas | |
DK0377437T3 (da) | Fremgangsmåde til fremstilling af 2,4-diamino-6-piperidinylpyrimidin-3-N-oxid | |
DK0656379T3 (da) | Fremgangsmåde til fremstilling af polyurethangenstande fra uretonimin-baserede sammensætninger | |
DK93884A (da) | Fremgangsmaade til fremstilling af 1,5-dibeskyttede-1,5,10-triazadecaner, mellemprodukter derfor samt disses fremstilling | |
DK0466887T3 (da) | Fremgangsmåde til fremstilling af pyrimidintrionderivater | |
SE7412789L (da) | ||
DK0515121T3 (da) | Fremgangsmåde til fremstilling af mellemprodukter for nizatidin og beslægtede forbindelser |