ATE137758T1 - Verfahren zur herstellung von nojirimycin- verbindungen - Google Patents

Verfahren zur herstellung von nojirimycin- verbindungen

Info

Publication number
ATE137758T1
ATE137758T1 AT90124580T AT90124580T ATE137758T1 AT E137758 T1 ATE137758 T1 AT E137758T1 AT 90124580 T AT90124580 T AT 90124580T AT 90124580 T AT90124580 T AT 90124580T AT E137758 T1 ATE137758 T1 AT E137758T1
Authority
AT
Austria
Prior art keywords
nojirimycin
compounds
producing
reductive amination
oxo
Prior art date
Application number
AT90124580T
Other languages
English (en)
Inventor
Peter B Anzeveno
Laura J Creemer
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of ATE137758T1 publication Critical patent/ATE137758T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT90124580T 1989-12-20 1990-12-18 Verfahren zur herstellung von nojirimycin- verbindungen ATE137758T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45364789A 1989-12-20 1989-12-20

Publications (1)

Publication Number Publication Date
ATE137758T1 true ATE137758T1 (de) 1996-05-15

Family

ID=23801471

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90124580T ATE137758T1 (de) 1989-12-20 1990-12-18 Verfahren zur herstellung von nojirimycin- verbindungen

Country Status (14)

Country Link
US (1) US5227479A (de)
EP (1) EP0433978B1 (de)
JP (1) JP2938193B2 (de)
KR (1) KR0147819B1 (de)
AT (1) ATE137758T1 (de)
AU (1) AU632191B2 (de)
DE (1) DE69026912T2 (de)
DK (1) DK0433978T3 (de)
ES (1) ES2088948T3 (de)
GR (1) GR3020492T3 (de)
HU (1) HU207866B (de)
IE (1) IE72513B1 (de)
IL (1) IL96694A (de)
ZA (1) ZA9010083B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5066807A (en) * 1990-03-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Process for the preparation of castanospermine
KR100446483B1 (ko) 2000-03-31 2004-09-01 미시간 스테이트 유니버시티 옥심 또는 이민으로부터 1,5-디데옥시-1,5-이미노 헥시톨제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634765A (en) * 1984-12-18 1987-01-06 Merrell Dow Pharmaceuticals Inc. Homodisaccharide hypoglycemic agents
DE3628486A1 (de) * 1986-08-22 1988-02-25 Bayer Ag Piperidinderivate
US4880917A (en) * 1988-07-01 1989-11-14 Merrell Dow Pharmaceuticals Inc. Process for hydrolyzing 2,6-dideoxy-2,6-iminoheptononitrile derivatives using trifluoroacetic acid and dinitrogen tetroxide
US4908439A (en) * 1988-09-16 1990-03-13 Merrell Dow Pharmaceuticals Inc. Synthesis of intermediate useful in the preparation of nojirimycin and related compounds

Also Published As

Publication number Publication date
HUT57224A (en) 1991-11-28
KR0147819B1 (ko) 1998-08-01
HU908300D0 (en) 1991-06-28
IE72513B1 (en) 1997-04-23
US5227479A (en) 1993-07-13
DK0433978T3 (da) 1996-05-28
JP2938193B2 (ja) 1999-08-23
JPH0418072A (ja) 1992-01-22
AU6808490A (en) 1991-06-27
KR910011882A (ko) 1991-08-07
AU632191B2 (en) 1992-12-17
IE904598A1 (en) 1991-07-03
ZA9010083B (en) 1991-10-30
EP0433978A2 (de) 1991-06-26
EP0433978A3 (en) 1992-09-09
EP0433978B1 (de) 1996-05-08
HU207866B (en) 1993-06-28
DE69026912D1 (de) 1996-06-13
ES2088948T3 (es) 1996-10-01
IL96694A (en) 1994-12-29
GR3020492T3 (en) 1996-10-31
DE69026912T2 (de) 1996-10-02
IL96694A0 (en) 1991-09-16

Similar Documents

Publication Publication Date Title
ATE153332T1 (de) Verfahren zur herstellung von oxetanonen
DE59209643D1 (de) Verfahren zur trennung von 5-methyl-tetrahydrofolsäure
DE3580657D1 (de) Verfahren zur herstellung von acylierten diketonischen verbindungen.
DE3854003D1 (de) Verfahren zur Herstellung von N-substituiertem Amin.
ATE116541T1 (de) Verfahren zur herstellung mikronisierter bioabbaubarer partikel.
DE69002680D1 (de) Verfahren zur herstellung von fluoralkylvinylverbindungen.
DE3864434D1 (de) Verfahren zur herstellung von aminen.
DE59004909D1 (de) Verfahren zur herstellung symmetrischer difettsäurediamide.
DE68902702D1 (de) Verfahren zur herstellung von synthetischem schmieroel durch olefinoligomerisation.
DE3578687D1 (de) N-substituierte neuraminsaeure-derivate und verfahren zu ihrer herstellung.
DE3667960D1 (de) Verfahren zur herstellung von halogen-magnesium-alanat und dessen verwendung.
DE69023328D1 (de) Verfahren zur herstellung von glycin.
DE3483624D1 (de) Verfahren zur herstellung von kornorientiertem siliziumstahl.
DE3879843D1 (de) Verfahren zur herstellung von 3,5,5-trimethylcyclohexa-2-en-1,4-dion.
DE68912809D1 (de) Verfahren zur Herstellung von Bis(2,2,6,6-tetramethyl-4-piperidyl)amin.
ATE137758T1 (de) Verfahren zur herstellung von nojirimycin- verbindungen
DE3667287D1 (de) Verfahren zur herstellung von bis(dialkylphenyl)pentaerythritoldiphosphiten.
DE69009394D1 (de) Verfahren zur Herstellung von 3-Cyano-3,5,5-trimethyl-1-cyclohexanon.
DE3580266D1 (de) Verfahren zur herstellung von aminoverbindungen aus hydroxylverbindungen.
DE59001534D1 (de) Verfahren zur herstellung von aminen.
DE3867192D1 (de) Verfahren zur herstellung von hydroxylammoniumsalz.
DE59010187D1 (de) Verfahren zur Herstellung von substituierten 2,4-Diamino-6-fluor-s-triazinen
DE3862210D1 (de) Verfahren zur herstellung von reinem bortrifluorid.
DE3784655D1 (de) Verfahren zur herstellung von ascorbinsaeure-2-phosphat.
DE69016380D1 (de) Verfahren zur Herstellung von molluskiziden 2,4,5-Tribrompyrrol-3-Carbonitrilen.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee