GT200800248A - Derivados de alcanos azabicíclicos sustituidos con bicicloheterociclos fusionados - Google Patents

Derivados de alcanos azabicíclicos sustituidos con bicicloheterociclos fusionados

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Publication number
GT200800248A
GT200800248A GT200800248A GT200800248A GT200800248A GT 200800248 A GT200800248 A GT 200800248A GT 200800248 A GT200800248 A GT 200800248A GT 200800248 A GT200800248 A GT 200800248A GT 200800248 A GT200800248 A GT 200800248A
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GT
Guatemala
Prior art keywords
derivatives
azabycyclic
substituted
reaches
fused bicycles
Prior art date
Application number
GT200800248A
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English (en)
Inventor
Ji Jianguo
Li Tao
Lynch Christopher
Gopalakrishnan Murali
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Publication date
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Publication of GT200800248A publication Critical patent/GT200800248A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/08—Diarylmethoxy radicals
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P37/02—Immunomodulators
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

DERIVADOS DE ALCANOS AZABICÍCLICOS SUSTITUIDOS CON BICÍCLICOS SUSTITUIDOS CON BICICLOHETEROCICLOS FUSIONADOS DE FÓRMULA GENERAL (I), COMPOSICIONES QUE COMPRENDEN DICHOS COMPUESTOS Y MÉTODOS DE TRATAMIENTO DE AFECCIONES Y TRASTORNOS USANDO DICHOS COMPUESTOS Y COMPOSICIONES.
GT200800248A 2006-05-19 2008-11-18 Derivados de alcanos azabicíclicos sustituidos con bicicloheterociclos fusionados GT200800248A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80219506P 2006-05-19 2006-05-19

Publications (1)

Publication Number Publication Date
GT200800248A true GT200800248A (es) 2009-12-02

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GT200800248A GT200800248A (es) 2006-05-19 2008-11-18 Derivados de alcanos azabicíclicos sustituidos con bicicloheterociclos fusionados

Country Status (30)

Country Link
US (2) US7872017B2 (es)
EP (2) EP2431368B1 (es)
JP (3) JP5420398B2 (es)
KR (1) KR20090018972A (es)
CN (2) CN101448825A (es)
AT (1) ATE529423T1 (es)
AU (1) AU2007253950B2 (es)
BR (1) BRPI0711588A2 (es)
CA (1) CA2647830C (es)
CY (1) CY1112531T1 (es)
DK (1) DK2018380T3 (es)
EC (1) ECSP088918A (es)
ES (2) ES2373792T3 (es)
GT (1) GT200800248A (es)
HK (1) HK1122569A1 (es)
HR (1) HRP20110917T1 (es)
IL (1) IL195234A0 (es)
MX (1) MX2008014672A (es)
MY (1) MY147661A (es)
NO (1) NO20085153L (es)
NZ (2) NZ589784A (es)
PL (1) PL2018380T3 (es)
PT (1) PT2018380E (es)
RS (1) RS52062B (es)
RU (2) RU2437884C2 (es)
SI (1) SI2018380T1 (es)
TW (1) TWI343385B (es)
UA (1) UA92083C2 (es)
WO (1) WO2007137030A2 (es)
ZA (2) ZA200810687B (es)

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