GR3035205T3 - Compounds related to the amidinium family, pharmaceutical compositions containing same, and uses thereof - Google Patents

Compounds related to the amidinium family, pharmaceutical compositions containing same, and uses thereof

Info

Publication number
GR3035205T3
GR3035205T3 GR20000402653T GR20000402653T GR3035205T3 GR 3035205 T3 GR3035205 T3 GR 3035205T3 GR 20000402653 T GR20000402653 T GR 20000402653T GR 20000402653 T GR20000402653 T GR 20000402653T GR 3035205 T3 GR3035205 T3 GR 3035205T3
Authority
GR
Greece
Prior art keywords
amidinium
family
pharmaceutical compositions
compositions containing
containing same
Prior art date
Application number
GR20000402653T
Other languages
English (en)
Inventor
Jean-Marie Lehn
Pierre Lehn
Jean-Pierre Vigneron
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26232562&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3035205(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR9602604A external-priority patent/FR2745569B1/fr
Priority claimed from FR9609557A external-priority patent/FR2751972B1/fr
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Publication of GR3035205T3 publication Critical patent/GR3035205T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GR20000402653T 1996-03-01 2001-01-11 Compounds related to the amidinium family, pharmaceutical compositions containing same, and uses thereof GR3035205T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9602604A FR2745569B1 (fr) 1996-03-01 1996-03-01 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications
FR9609557A FR2751972B1 (fr) 1996-07-30 1996-07-30 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications
PCT/FR1997/000364 WO1997031935A1 (fr) 1996-03-01 1997-02-28 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications

Publications (1)

Publication Number Publication Date
GR3035205T3 true GR3035205T3 (en) 2001-04-30

Family

ID=26232562

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000402653T GR3035205T3 (en) 1996-03-01 2001-01-11 Compounds related to the amidinium family, pharmaceutical compositions containing same, and uses thereof

Country Status (18)

Country Link
US (2) US6143729A (el)
EP (1) EP0888379B1 (el)
JP (1) JP4271260B2 (el)
KR (1) KR19990087372A (el)
AT (1) ATE198599T1 (el)
AU (1) AU723998B2 (el)
BR (1) BRPI9707889B8 (el)
CZ (1) CZ295225B6 (el)
DE (1) DE69703878T2 (el)
DK (1) DK0888379T3 (el)
ES (1) ES2154453T3 (el)
GR (1) GR3035205T3 (el)
HU (1) HU228072B1 (el)
IL (1) IL125926A (el)
NO (1) NO311806B1 (el)
PT (1) PT888379E (el)
SK (1) SK283575B6 (el)
WO (1) WO1997031935A1 (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884430B1 (en) * 1997-02-10 2005-04-26 Aventis Pharma S.A. Formulation of stabilized cationic transfection agent(s) /nucleic acid particles
FR2763943B1 (fr) * 1997-05-28 1999-07-09 Rhone Poulenc Rorer Sa Composes, leur preparation et leur utilisation pour le transfert d'acides nucleiques dans les cellules
FR2777017B1 (fr) * 1998-04-02 2002-08-23 Rhone Poulenc Rorer Sa Nouveaux agents de transfert d'acides nucleiques, compositions les contenant et leurs applications
BR9909350A (pt) * 1998-04-02 2000-12-12 Aventis Pharma Sa Compostos, composição, utilização de um composto, e, processos para preparação dos compostos, para transferência de ácido nucleicos para as células e para tratamento de doenças por meio de administração de um ácido nucleico
DE10109898A1 (de) 2001-02-21 2002-09-05 Novosom Gmbh Lipide mit veränderlicher Ladung
FR2824557B1 (fr) * 2001-05-14 2003-08-29 Aventis Pharma Sa Derives lipidiques de polythiouree
WO2002092558A1 (fr) * 2001-05-14 2002-11-21 Gencell S.A. Derives lipidiques de polythiouree
FR2829136B1 (fr) * 2001-08-29 2006-11-17 Aventis Pharma Sa Derives lipidiques d'aminoglycosides
SI1479985T1 (sl) 2002-01-17 2017-10-30 Alfa Laval Corporate Ab Potopni uparjalnik, ki vsebuje ploščni toplotni izmenjevalnik in cilindrično ohišje, kjer je nameščen ploščni toplotni izmenjevalnik
JP4980893B2 (ja) * 2005-04-28 2012-07-18 日本曹達株式会社 新規なグアニジン化合物、製造方法及びそれらを含有する殺菌性組成物
EP2069500B1 (en) * 2006-10-04 2014-09-24 Centre National De La Recherche Scientifique (Cnrs) Compositions comprising a sirna and lipidic 4,5-disubstituted 2-deoxystreptamine ring aminoglycoside derivatives and uses thereof
JP2012509258A (ja) * 2008-11-17 2012-04-19 エンゾン ファーマシューティカルズ，インコーポレーテッド 核酸送達系のための分岐カチオン性脂質

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283185A (en) * 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
CA2176715A1 (en) * 1993-11-24 1995-06-01 Timothy D. Heath Amphiphilic derivatives of guanidine
US5777153A (en) * 1994-07-08 1998-07-07 Gilead Sciences, Inc. Cationic lipids
US6071890A (en) * 1994-12-09 2000-06-06 Genzyme Corporation Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
US5811406A (en) * 1995-06-07 1998-09-22 Regents Of The University Of California Dry powder formulations of polynucleotide complexes

Also Published As

Publication number Publication date
IL125926A (en) 2004-09-27
DE69703878D1 (de) 2001-02-15
HUP9902465A1 (hu) 1999-12-28
US6143729A (en) 2000-11-07
JP2000506136A (ja) 2000-05-23
BR9707889B1 (pt) 2010-03-23
HU228072B1 (en) 2012-09-28
CZ295225B6 (cs) 2005-06-15
DE69703878T2 (de) 2001-04-26
DK0888379T3 (da) 2001-01-29
IL125926A0 (en) 1999-04-11
AU723998B2 (en) 2000-09-07
ATE198599T1 (de) 2001-01-15
NO983691D0 (no) 1998-08-12
ES2154453T3 (es) 2001-04-01
JP4271260B2 (ja) 2009-06-03
EP0888379A1 (fr) 1999-01-07
KR100452062B1 (el) 2005-04-08
SK283575B6 (sk) 2003-09-11
BR9707889A (pt) 2000-01-04
NO311806B1 (no) 2002-01-28
CZ277298A3 (cs) 1998-12-16
WO1997031935A1 (fr) 1997-09-04
US6316422B1 (en) 2001-11-13
KR19990087372A (ko) 1999-12-27
EP0888379B1 (fr) 2001-01-10
SK118298A3 (en) 1999-02-11
NO983691L (no) 1998-08-12
PT888379E (pt) 2001-05-31
HUP9902465A3 (en) 2009-10-28
AU1930497A (en) 1997-09-16
BRPI9707889B8 (pt) 2016-11-08

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