GR3002559T3 - Continuous pelleting-process - Google Patents

Continuous pelleting-process

Info

Publication number
GR3002559T3
GR3002559T3 GR91400710T GR910400710T GR3002559T3 GR 3002559 T3 GR3002559 T3 GR 3002559T3 GR 91400710 T GR91400710 T GR 91400710T GR 910400710 T GR910400710 T GR 910400710T GR 3002559 T3 GR3002559 T3 GR 3002559T3
Authority
GR
Greece
Prior art keywords
pelleting
continuous
continuous pelleting
Prior art date
Application number
GR91400710T
Other languages
English (en)
Inventor
Roger Guenther Dr Klimesch
Gerhard Bleckmann
Karl-Peter Farwerck
Hans-Helmut Dr Goertz
Lothar Schlemmer
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of GR3002559T3 publication Critical patent/GR3002559T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B9/00—Making granules
    • B29B9/02—Making granules by dividing preformed material
    • B29B9/06—Making granules by dividing preformed material in the form of filamentary material, e.g. combined with extrusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/16—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using pocketed rollers, e.g. two co-operating pocketed rollers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/30—Feeding material to presses
    • B30B15/302—Feeding material in particulate or plastic state to moulding presses
    • B30B15/308—Feeding material in particulate or plastic state to moulding presses in a continuous manner, e.g. for roller presses, screw extrusion presses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00—General characteristics or adaptations
    • A61J2200/20—Extrusion means, e.g. for producing pharmaceutical forms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2503/00—Use of resin-bonded materials as filler
GR91400710T 1986-04-11 1991-06-03 Continuous pelleting-process GR3002559T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863612211 DE3612211A1 (de) 1986-04-11 1986-04-11 Kontinuierliches verfahren zum tablettieren

Publications (1)

Publication Number Publication Date
GR3002559T3 true GR3002559T3 (en) 1993-01-25

Family

ID=6298472

Family Applications (1)

Application Number Title Priority Date Filing Date
GR91400710T GR3002559T3 (en) 1986-04-11 1991-06-03 Continuous pelleting-process

Country Status (18)

Country Link
US (1) US4880585A (el)
EP (1) EP0240906B1 (el)
JP (1) JPH078293B2 (el)
KR (1) KR940005302B1 (el)
CN (1) CN1056508C (el)
AR (1) AR241630A1 (el)
AT (1) ATE63056T1 (el)
AU (1) AU590697B2 (el)
CA (1) CA1303501C (el)
CS (1) CS270222B2 (el)
DE (2) DE3612211A1 (el)
ES (1) ES2022188B3 (el)
FI (1) FI88577C (el)
GR (1) GR3002559T3 (el)
HU (1) HUT55218A (el)
NO (1) NO173588C (el)
PT (1) PT84660B (el)
YU (1) YU45412B (el)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051261A (en) * 1987-11-24 1991-09-24 Fmc Corporation Method for preparing a solid sustained release form of a functionally active composition
DE3812567A1 (de) * 1988-04-15 1989-10-26 Basf Ag Verfahren zur herstellung pharmazeutischer mischungen
DE3830353A1 (de) * 1988-09-07 1990-03-15 Basf Ag Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen
US5073323A (en) * 1990-05-30 1991-12-17 Washington Mills Ceramics Corporation Method and apparatus for producing compacted particulate articles
DE4031881C2 (de) * 1990-10-08 1994-02-24 Sanol Arznei Schwarz Gmbh Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung
EP0580860B2 (en) * 1991-04-16 2004-12-15 Nippon Shinyaku Company, Limited Method of manufacturing solid dispersion
DE4138513A1 (de) * 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
EP0717988B1 (en) * 1993-08-20 2001-10-17 Nippon Shinyaku Company, Limited Gastric remaining preparation, swollen molding, and production process
EP0753998B2 (en) * 1994-03-09 2005-11-02 Wm. Wrigley Jr. Company Method and apparatus for forming miniature size confectionery products
DE4413350A1 (de) 1994-04-18 1995-10-19 Basf Ag Retard-Matrixpellets und Verfahren zu ihrer Herstellung
DE19509807A1 (de) * 1995-03-21 1996-09-26 Basf Ag Verfahren zur Herstellung von Wirkstoffzubereitungen in Form einer festen Lösung des Wirkstoffs in einer Polymermatrix sowie mit diesem Verfahren hergestellte Wirkstoffzubereitungen
GB9422154D0 (en) * 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE4446468A1 (de) * 1994-12-23 1996-06-27 Basf Ag Verfahren zur Herstellung von umhüllten Tabletten
DE4446467A1 (de) * 1994-12-23 1996-06-27 Basf Ag Verfahren zur Herstellung von linsenförmigen Tabletten durch Schmelzkalandrierung
DE4446470A1 (de) * 1994-12-23 1996-06-27 Basf Ag Verfahren zur Herstellung von teilbaren Tabletten
DE19504832A1 (de) * 1995-02-14 1996-08-22 Basf Ag Feste Wirkstoff-Zubereitungen
US5900425A (en) * 1995-05-02 1999-05-04 Bayer Aktiengesellschaft Pharmaceutical preparations having controlled release of active compound and processes for their preparation
DE19536394A1 (de) 1995-09-29 1997-04-03 Basf Ag Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze
DE19539359A1 (de) * 1995-10-23 1997-04-24 Knoll Ag Formbandkalander
DE19539361A1 (de) * 1995-10-23 1997-04-24 Basf Ag Verfahren zur Herstellung von mehrschichtigen, festen Arzneiformen zur oralen oder rektalen Verabreichung
DE19629040A1 (de) * 1996-07-19 1998-01-22 Basf Ag Pflanzenextrakthaltige Arzneiformen
DE19629753A1 (de) * 1996-07-23 1998-01-29 Basf Ag Verfahren zur Herstellung von festen Arzneiformen
DE19635676A1 (de) * 1996-09-03 1998-03-05 Basf Ag Feste geschäumte Wirkstoffzubereitungen
TW474824B (en) 1996-09-13 2002-02-01 Basf Ag The production of solid pharmaceutical forms
DE19710213A1 (de) * 1997-03-12 1998-09-17 Basf Ag Verfahren zur Herstellung von festen Kombinationsarzneiformen
DE19733504A1 (de) * 1997-08-01 1999-02-04 Basf Ag Langsam sinkende Pellets oder Granulate für die Fischzucht
DE19753298A1 (de) 1997-12-01 1999-06-02 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
AU8621398A (en) * 1998-01-12 1999-07-26 Buhler Ag Method and device for capsulating active ingredients
US6787157B1 (en) * 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
DE19812688A1 (de) 1998-03-23 1999-09-30 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
DK1083790T3 (da) 1998-04-30 2004-06-01 Basf Ag Retardformuleringer af aktive stoffer til plantebeskyttelse
DE19839276A1 (de) 1998-08-28 2000-03-02 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
DE19840256A1 (de) 1998-09-03 2000-03-09 Basf Ag Verfahren zur Herstellung von beschichteten festen Dosierungsformen
DE19841244A1 (de) 1998-09-09 2000-03-16 Knoll Ag Verfahren und Vorrichtung zum Herstellen von Tabletten
DE19842753A1 (de) 1998-09-18 2000-03-23 Bayer Ag Agitationsunabhängige pharmazeutische Retardzubereitungen und Verfahren zu ihrer Herstellung
DE19843904A1 (de) 1998-09-24 2000-03-30 Basf Ag Feste Dosierungsform mit polymerem Bindemittel
DE19847618A1 (de) 1998-10-15 2000-04-20 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
DE19853985A1 (de) 1998-11-23 2000-05-25 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
DE19901383A1 (de) 1999-01-15 2000-07-20 Knoll Ag Verfahren zur Herstellung unterschiedlicher fester Dosierungsformen
DE19913692A1 (de) 1999-03-25 2000-09-28 Basf Ag Mechanisch stabile pharmazeutische Darreichungsformen, enthaltend flüssige oder halbfeste oberflächenaktive Substanzen
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
ATE308897T1 (de) 1999-09-06 2005-11-15 Firmenich & Cie Verfahren zur herstellung von granulaten für die kontrollierte freigabe der flüchtigen verbindungen
DE19943501A1 (de) 1999-09-10 2001-03-15 Basf Ag Unterwassergranulation wirkstoffhaltiger Schmelzen
ATE266996T1 (de) * 1999-10-13 2004-06-15 Novo Nordisk As Verfahren zum herstellung von medizinische formkörpern
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
JP5767429B2 (ja) 1999-11-12 2015-08-19 アッヴィ・インコーポレイテッド 固体分散剤中の結晶化阻害剤
GB9927682D0 (en) * 1999-11-23 2000-01-19 Unilever Plc Process for the manufacture of shaped articles
DE10017102A1 (de) 2000-04-06 2001-10-11 Basf Ag Verfahren zur Herstellung von festen Kreatin-Dosierungsformen und dadurch erhältliche Dosierungsformen
GB0008553D0 (en) * 2000-04-06 2000-05-24 Unilever Plc Process and apparatus for the production of a detergent bar
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
DE10038571A1 (de) * 2000-08-03 2002-02-14 Knoll Ag Zusammensetzungen und Dosierungsformen zur Anwendung in der Mundhöhle bei der Bhandlung von Mykosen
DE10046541A1 (de) * 2000-09-19 2002-03-28 Knoll Ag Mechanisch stabile darreichungsformen, enthaltend Ubichinone
US6767619B2 (en) * 2001-05-17 2004-07-27 Charles R. Owens Preform for manufacturing a material having a plurality of voids and method of making the same
GB0113841D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
US20030203027A1 (en) * 2002-04-26 2003-10-30 Ethicon, Inc. Coating technique for deposition of drug substance on a substrate
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
DE10247037A1 (de) * 2002-10-09 2004-04-22 Abbott Gmbh & Co. Kg Herstellung von festen Dosierungsformen unter Verwendung eines vernetzten nichtthermoplastischen Trägers
US6797213B2 (en) * 2002-10-15 2004-09-28 Frito-Lay North America, Inc Method and apparatus for producing a curly puff extrudate
ATE359777T1 (de) * 2002-12-17 2007-05-15 Abbott Gmbh & Co Kg Fenofibratsäure enthaltende pharmazeutische zusammensetzung und deren physiologisch verträgliche salze und derivate
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
US7423004B2 (en) * 2003-01-31 2008-09-09 Smithkline Beecham Corporation Solid dispersion compositions
US9579286B2 (en) 2003-04-21 2017-02-28 Purdue Pharma L.P. Tamper resistant dosage form comprising co-extruded, sequestered adverse agent particles and process of making same
US8075872B2 (en) 2003-08-06 2011-12-13 Gruenenthal Gmbh Abuse-proofed dosage form
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
WO2005055981A2 (en) * 2003-12-09 2005-06-23 Euro-Celtique S.A. Tamper resistant co-extruded dosage form containing an active agent and an adverse agent and process of making same
US8883204B2 (en) 2003-12-09 2014-11-11 Purdue Pharma L.P. Tamper resistant co-extruded dosage form containing an active agent and an adverse agent and process of making same
GB2409204A (en) * 2003-12-19 2005-06-22 Reckitt Benckiser Nv Plasticized thermoplastic polymer
PL1748762T3 (pl) 2004-05-28 2014-05-30 Abbvie Deutschland Postać dawkowania, dająca się otrzymać ze sproszkowanej mieszaniny zawierającej nieorganiczny pigment
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) * 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
ATE476997T1 (de) * 2005-07-05 2010-08-15 Abbott Gmbh & Co Kg Zusammensetzung und dosierform mit einer festen oder halbfesten matrix
JP2009504590A (ja) 2005-08-08 2009-02-05 アボット ゲーエムベーハー ウント コンパニー カーゲー 改善された生物学的利用能をもつ剤型
WO2007017248A2 (en) 2005-08-08 2007-02-15 Abbott Gmbh & Co. Kg Itraconazole compositions with improved bioavailability
EP1832281A1 (en) * 2006-03-10 2007-09-12 Abbott GmbH & Co. KG Process for producing a solid dispersion of an active ingredient
WO2007131019A2 (en) * 2006-05-04 2007-11-15 Ethicon, Inc. Tissue holding devices and methods for making the same
EP1925441A1 (de) 2006-11-24 2008-05-28 Abbott GmbH & Co. KG Vorrichtung und Verfahren zum Bilden von Formlingen aus einer formbaren Masse
EP1925442A1 (de) 2006-11-24 2008-05-28 Abbott GmbH & Co. KG Hochleistungs-Rotationsumlauf-Form-Verfahren und -Vorrichtung
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
US8562644B2 (en) * 2007-08-06 2013-10-22 Ethicon, Inc. Barbed suture with non-symmetric barbs
AU2008303129B2 (en) * 2007-09-25 2013-08-01 Formulex Pharma Innovations Ltd. Compositions comprising lipophilic active compounds and method for their preparation
AU2009207796B2 (en) 2008-01-25 2014-03-27 Grunenthal Gmbh Pharmaceutical dosage form
ES2599031T3 (es) 2008-05-09 2017-01-31 Grünenthal GmbH Proceso para la preparación de una formulación de polvo intermedia y una forma de dosificación solida final utilizando un paso de congelación por pulverización
ES2402108T3 (es) 2009-03-26 2013-04-29 Swiss Caps Rechte Und Lizenzen Ag Método y dispositivo para fabricar cápsulas blandas
NZ596667A (en) 2009-07-22 2013-09-27 Gruenenthal Chemie Hot-melt extruded controlled release dosage form
PT2456424E (pt) 2009-07-22 2013-09-30 Gruenenthal Gmbh Forma de dosagem resistente à adulteração e estabilizada contra a oxidação
WO2011095314A2 (en) 2010-02-03 2011-08-11 Grünenthal GmbH Preparation of a powdery pharmaceutical composition by means of an extruder
CA2808541C (en) 2010-09-02 2019-01-08 Gruenenthal Gmbh Tamper resistant dosage form comprising an anionic polymer
CN103179956A (zh) 2010-09-02 2013-06-26 格吕伦塔尔有限公司 包含阴离子聚合物的抗破碎剂型
MX2013002377A (es) 2010-09-02 2013-04-29 Gruenenthal Gmbh Forma de dosificacion resistente a manipulacion que comprende una sal inorganica.
EP2463327A3 (de) 2010-12-10 2015-06-03 Basf Se Verfahren zur herstellung von granulaten, enthaltend mindestens eine wasserlösliche komponente
CN103260609B (zh) 2010-12-23 2017-08-11 雅培股份有限两合公司 基于固体分散体的固体延缓制剂
AR087360A1 (es) 2011-07-29 2014-03-19 Gruenenthal Gmbh Tableta a prueba de manipulacion que proporciona liberacion de farmaco inmediato
MX348054B (es) 2011-07-29 2017-05-25 Gruenenthal Gmbh Tableta a prueba de alteracion que proporciona liberacion inmediata del farmaco.
KR101274387B1 (ko) * 2011-09-03 2013-06-17 김경란 구형물 성형장치
KR101437423B1 (ko) * 2011-12-21 2014-09-11 권오익 다공판이 구비된 환 제조장치
AU2013225106B2 (en) 2012-02-28 2017-11-02 Grunenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
RS57913B1 (sr) 2012-04-18 2019-01-31 Gruenenthal Gmbh Farmaceutske dozne forme otporne na neovlašćenu upotrebu i naglo oslobađanje celokupne doze
PL2846835T3 (pl) 2012-05-11 2018-02-28 Grünenthal GmbH Kształtowana termicznie, odporna na manipulacje farmaceutyczna postać dawkowania zawierająca cynk
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
CN103478878A (zh) * 2012-06-12 2014-01-01 昆山市张浦镇合通网络科技服务部 简易快捷制块机
DE102013003032A1 (de) * 2013-02-22 2014-09-25 Automatik Plastics Machinery Gmbh Quetschwalzengranulator und Verwendung desselben
WO2014139803A1 (en) * 2013-03-15 2014-09-18 AbbVie Deutschland GmbH & Co. KG Process and apparatus for metering a plasticized formulation
JP6466417B2 (ja) 2013-05-29 2019-02-06 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 二峰性放出プロファイルを有する改変防止（ｔａｍｐｅｒ−ｒｅｓｉｓｔａｎｔ）剤形
JP6445537B2 (ja) 2013-05-29 2018-12-26 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング １個または複数の粒子を含有する改変防止（ｔａｍｐｅｒ−ｒｅｓｉｓｔａｎｔ）剤形
JP6449871B2 (ja) 2013-07-12 2019-01-09 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング エチレン−酢酸ビニルポリマーを含有する改変防止剤形
BR112016010482B1 (pt) 2013-11-26 2022-11-16 Grünenthal GmbH Preparação de uma composição farmacêutica em pó por meio de criomoagem
US20150164807A1 (en) 2013-12-16 2015-06-18 Grünenthal GmbH Tamper resistant dosage form with bimodal release profile manufactured by co-extrusion
WO2015173195A1 (en) 2014-05-12 2015-11-19 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
JP2017516789A (ja) 2014-05-26 2017-06-22 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング エタノール過量放出に対して防護されている多粒子
DE202014008800U1 (de) * 2014-11-05 2014-11-17 Automatik Plastics Machinery Gmbh Quetschwalzengranulator mit Quetschwalzenpaar und Verwendung desselben
WO2016124530A1 (en) 2015-02-03 2016-08-11 Grünenthal GmbH Tamper-resistant dosage form comprising a polyethylene glycol graft copolymer
EA035434B1 (ru) 2015-04-24 2020-06-15 Грюненталь Гмбх Защищенная от применения не по назначению лекарственная форма с немедленным высвобождением и устойчивостью к экстракции растворителями
US10842750B2 (en) 2015-09-10 2020-11-24 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
JP2017137279A (ja) * 2016-02-04 2017-08-10 秀介 大友 連結状態で一個ずつ又は複数個ずつ自由に分割できる錠剤
EP3490537A1 (en) 2016-08-01 2019-06-05 Grünenthal GmbH Tamper resistant dosage form comprising an anionic polysaccharide
CN107714654A (zh) * 2016-08-11 2018-02-23 董玲 一种冻干制剂及其制备方法
JP2019524761A (ja) 2016-08-12 2019-09-05 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング エフェドリン及びその誘導体の改変防止製剤
BE1024283B1 (fr) * 2016-10-10 2018-01-12 Universite De Liege Appareillage pour la production en continu de formes orales solides
CN106827289A (zh) * 2017-03-28 2017-06-13 洛阳欧祺精密零件制造有限公司 一种造粒机
TW202002957A (zh) 2018-02-09 2020-01-16 德商歌林達有限公司 包含轉化抑制劑之麻黃素及其衍生物之抗損壞調配物

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US99083A (en) * 1870-01-25 Improvement in moulding and glazing forms made of plastic material
FR537444A (fr) * 1920-11-24 1922-05-23 Machine pour la fabrication des cachets pharmaceutiques
US2988774A (en) * 1957-07-22 1961-06-20 Lever Brothers Ltd Method and apparatus for the production of soap tablets
DE1766546C3 (de) * 1968-06-11 1974-11-28 Karl Gunnar Lidingoe Eriksson Verfahren zum Herstellen von festen dragee- oder tablettenförmigen Arzneimittelzubereitungen
US3755527A (en) * 1969-10-09 1973-08-28 Exxon Research Engineering Co Process for producing melt blown nonwoven synthetic polymer mat having high tear resistance
BE795766A (fr) * 1972-02-22 1973-08-22 Lilly Co Eli Particules de napsylate de propoxyphene retard et procede de fabrication de ces particules
US3859407A (en) * 1972-05-15 1975-01-07 Corning Glass Works Method of manufacturing particles of uniform size and shape
DE2241616C3 (de) * 1972-08-24 1978-07-13 Buss Ag, Basel (Schweiz) Verfahren und Vorrichtung zur Aufbereitung von Polyadditionsharzzwischenprodukten
US3843299A (en) * 1972-09-01 1974-10-22 V Minchenko Device for shaping spherical pellets
US4028024A (en) * 1974-10-31 1977-06-07 Moreland Stephen T Manufacture of filled capsules or the like
IT1065137B (it) * 1976-08-05 1985-02-25 Sir Soc Italiana Resine Spa Composizioni da stampaggio comprendenti una resina fenolica novolacca e procedimento per la loro preparazione
US4130521A (en) * 1977-04-25 1978-12-19 Chevron Research Company Densification of polypyrrolidone
US4256448A (en) * 1978-03-09 1981-03-17 Usm Corporation Roller die
AU525847B2 (en) * 1978-03-09 1982-12-02 Usm Corp. Roller die 0
US4165978A (en) * 1978-07-14 1979-08-28 Midrex Corporation Briquet sheet breaking by cooling and bending
JPS56160900A (en) * 1980-05-16 1981-12-10 Mitsubishi Heavy Ind Ltd Briquette machine
US4340557A (en) * 1980-12-16 1982-07-20 Ball Corporation Method of making unfestooned plastic containers from polygonal blanks
US4411161A (en) * 1981-08-10 1983-10-25 International Telephone & Telegraph Corporation Mass flowmeter or the like
US4451260A (en) * 1982-03-26 1984-05-29 Minnesota Mining And Manufacturing Company Sustained release oral medicinal delivery device
US4520179A (en) * 1982-09-20 1985-05-28 Gaf Corporation Preparation of vinylpyrrolidone/vinyl acetate copolymers of various molecular weights using a single initiator system consisting essentially of t-Butylperoxypivalate
US4520180A (en) * 1982-09-20 1985-05-28 Gaf Corporation Polymerization of vinylpyrrolidone to various molecular weights using a single initiator system consisting essentially of t-Butylperoxypivalate
JPS59222406A (ja) * 1983-06-01 1984-12-14 Teijin Ltd 歯周疾患治療用製剤及びその製造法
DE3612212A1 (de) * 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen

Also Published As

Publication number Publication date
CS253187A2 (en) 1989-10-13
KR870009705A (ko) 1987-11-30
FI88577B (fi) 1993-02-26
NO173588C (no) 1994-01-05
CA1303501C (en) 1992-06-16
CN87102755A (zh) 1987-10-28
EP0240906A2 (de) 1987-10-14
YU59087A (en) 1989-12-31
AU7140087A (en) 1987-10-15
CS270222B2 (en) 1990-06-13
NO871512D0 (no) 1987-04-10
JPH078293B2 (ja) 1995-02-01
US4880585A (en) 1989-11-14
KR940005302B1 (ko) 1994-06-16
NO871512L (no) 1987-10-12
NO173588B (no) 1993-09-27
ES2022188B3 (es) 1991-12-01
AR241630A1 (es) 1992-10-30
JPS62240061A (ja) 1987-10-20
PT84660B (pt) 1989-11-30
HUT55218A (en) 1991-05-28
DE3769687D1 (de) 1991-06-06
FI871538A (fi) 1987-10-12
YU45412B (en) 1992-05-28
PT84660A (en) 1987-05-01
EP0240906B1 (de) 1991-05-02
FI871538A0 (fi) 1987-04-08
AU590697B2 (en) 1989-11-09
EP0240906A3 (en) 1988-08-03
ATE63056T1 (de) 1991-05-15
FI88577C (fi) 1993-06-10
CN1056508C (zh) 2000-09-20
DE3612211A1 (de) 1987-10-15

Similar Documents

Publication Publication Date Title
GR3002559T3 (en) Continuous pelleting-process
AU99209S (en) Whirlpool-spa
CS1003586A1 (en) Zpusob tepelneho zpracovani povrchu tenkostennych tvarovanych trubkovitych strojnich nebo konstrukcnich soucasti
AU98619S (en) Gamesboard
CA56534S (en) Boardgame
CA57727S (en) Loudspeaker-cabinet
CA57366S (en) Loudspeaker-cabinet
CA57305S (en) Dictating-machine
CA55743S (en) Boardgame
CA56175S (en) Presse-ail
CA56801S (en) Eyeguard
CA57574S (en) Vitrine
CA57575S (en) Vitrine
CA57624S (en) Chemisier
AU95106S (en) Tea-towel
CS1011986A1 (en) Zpusob odstranovani deforamci stojanu stroju
CS1003486A1 (en) Zpusob pripravy nitrozilni tukove emulze
CS1013286A1 (en) Oddelovaci ustroji kontrolniho automatu
CS593786A1 (en) Zapojeni programovatelneho ridiciho systemu
CS415486A1 (en) Pneumaticka tlumena pruzina
BG41503A1 (en) Shampoon
BG42156A1 (en) Videocontroller
CS1003886A1 (en) Povlak snizujici odrazivost laseroveho zareni
CS222986A1 (en) Trpytka
CS1008986A1 (en) Zpusob pripravy cyklo tetrafosforecnanu dihorecnateho