AR241630A1 - Procedimiento continuo para la elaboracion de comprimidos de mezclas farmaceuticas y dispositivo para llevar a la practica dicho procedimiento. - Google Patents
Procedimiento continuo para la elaboracion de comprimidos de mezclas farmaceuticas y dispositivo para llevar a la practica dicho procedimiento.Info
- Publication number
- AR241630A1 AR241630A1 AR87307264A AR30726487A AR241630A1 AR 241630 A1 AR241630 A1 AR 241630A1 AR 87307264 A AR87307264 A AR 87307264A AR 30726487 A AR30726487 A AR 30726487A AR 241630 A1 AR241630 A1 AR 241630A1
- Authority
- AR
- Argentina
- Prior art keywords
- environments
- continuous
- pelleting
- tablets
- reciprocamily
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B9/00—Making granules
- B29B9/02—Making granules by dividing preformed material
- B29B9/06—Making granules by dividing preformed material in the form of filamentary material, e.g. combined with extrusion
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/16—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using pocketed rollers, e.g. two co-operating pocketed rollers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/30—Feeding material to presses
- B30B15/302—Feeding material in particulate or plastic state to moulding presses
- B30B15/308—Feeding material in particulate or plastic state to moulding presses in a continuous manner, e.g. for roller presses, screw extrusion presses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2200/00—General characteristics or adaptations
- A61J2200/20—Extrusion means, e.g. for producing pharmaceutical forms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2503/00—Use of resin-bonded materials as filler
Abstract
PROCEDIMIENTO CONTINUO PARA LA ELABORACION DE COMPRIMIDOS DE MEZCLAS FARMACEUTICAS, LA MEZCLA SE EXTRUSIONA Y LA MASA CONTINUA AUN MOLDEABLE SE PRENSA ENTRE DOS CILINDROS ACCIONADOS EN SENTIDOS RECIPROCAMENTE CONTRARIOS Y PROVISTOS CON CAVIDADES ENFRENTADAS UNAS A OTRAS EN LA ENVOLVENTE DE CILINDRO, CAVIDADES CUYA EJECUCION DETERMINA LA FORMA DE LOS COMPRIMIDOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19863612211 DE3612211A1 (de) | 1986-04-11 | 1986-04-11 | Kontinuierliches verfahren zum tablettieren |
Publications (1)
Publication Number | Publication Date |
---|---|
AR241630A1 true AR241630A1 (es) | 1992-10-30 |
Family
ID=6298472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR87307264A AR241630A1 (es) | 1986-04-11 | 1987-04-09 | Procedimiento continuo para la elaboracion de comprimidos de mezclas farmaceuticas y dispositivo para llevar a la practica dicho procedimiento. |
Country Status (18)
Country | Link |
---|---|
US (1) | US4880585A (es) |
EP (1) | EP0240906B1 (es) |
JP (1) | JPH078293B2 (es) |
KR (1) | KR940005302B1 (es) |
CN (1) | CN1056508C (es) |
AR (1) | AR241630A1 (es) |
AT (1) | ATE63056T1 (es) |
AU (1) | AU590697B2 (es) |
CA (1) | CA1303501C (es) |
CS (1) | CS270222B2 (es) |
DE (2) | DE3612211A1 (es) |
ES (1) | ES2022188B3 (es) |
FI (1) | FI88577C (es) |
GR (1) | GR3002559T3 (es) |
HU (1) | HUT55218A (es) |
NO (1) | NO173588C (es) |
PT (1) | PT84660B (es) |
YU (1) | YU45412B (es) |
Families Citing this family (127)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5051261A (en) * | 1987-11-24 | 1991-09-24 | Fmc Corporation | Method for preparing a solid sustained release form of a functionally active composition |
DE3812567A1 (de) * | 1988-04-15 | 1989-10-26 | Basf Ag | Verfahren zur herstellung pharmazeutischer mischungen |
DE3830353A1 (de) * | 1988-09-07 | 1990-03-15 | Basf Ag | Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen |
US5073323A (en) * | 1990-05-30 | 1991-12-17 | Washington Mills Ceramics Corporation | Method and apparatus for producing compacted particulate articles |
DE4031881C2 (de) * | 1990-10-08 | 1994-02-24 | Sanol Arznei Schwarz Gmbh | Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung |
JP2527107B2 (ja) * | 1991-04-16 | 1996-08-21 | 日本新薬株式会社 | 固体分散体の製造方法 |
DE4138513A1 (de) * | 1991-11-23 | 1993-05-27 | Basf Ag | Feste pharmazeutische retardform |
US6312726B1 (en) * | 1993-08-20 | 2001-11-06 | Nippon Shinyaku Co., Ltd. | Gastric remaining preparation, swollen molding, and production process |
CA2184812C (en) * | 1994-03-09 | 1999-12-28 | Ronald L. Ream | Method and apparatus for forming miniature size confectionery products |
DE4413350A1 (de) | 1994-04-18 | 1995-10-19 | Basf Ag | Retard-Matrixpellets und Verfahren zu ihrer Herstellung |
DE19509807A1 (de) * | 1995-03-21 | 1996-09-26 | Basf Ag | Verfahren zur Herstellung von Wirkstoffzubereitungen in Form einer festen Lösung des Wirkstoffs in einer Polymermatrix sowie mit diesem Verfahren hergestellte Wirkstoffzubereitungen |
GB9422154D0 (en) * | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
US5965161A (en) † | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
DE4446468A1 (de) * | 1994-12-23 | 1996-06-27 | Basf Ag | Verfahren zur Herstellung von umhüllten Tabletten |
DE4446467A1 (de) * | 1994-12-23 | 1996-06-27 | Basf Ag | Verfahren zur Herstellung von linsenförmigen Tabletten durch Schmelzkalandrierung |
DE4446470A1 (de) * | 1994-12-23 | 1996-06-27 | Basf Ag | Verfahren zur Herstellung von teilbaren Tabletten |
DE19504832A1 (de) * | 1995-02-14 | 1996-08-22 | Basf Ag | Feste Wirkstoff-Zubereitungen |
US5900425A (en) * | 1995-05-02 | 1999-05-04 | Bayer Aktiengesellschaft | Pharmaceutical preparations having controlled release of active compound and processes for their preparation |
DE19536394A1 (de) | 1995-09-29 | 1997-04-03 | Basf Ag | Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze |
DE19539361A1 (de) * | 1995-10-23 | 1997-04-24 | Basf Ag | Verfahren zur Herstellung von mehrschichtigen, festen Arzneiformen zur oralen oder rektalen Verabreichung |
DE19539359A1 (de) * | 1995-10-23 | 1997-04-24 | Knoll Ag | Formbandkalander |
DE19629040A1 (de) * | 1996-07-19 | 1998-01-22 | Basf Ag | Pflanzenextrakthaltige Arzneiformen |
DE19629753A1 (de) * | 1996-07-23 | 1998-01-29 | Basf Ag | Verfahren zur Herstellung von festen Arzneiformen |
DE19635676A1 (de) * | 1996-09-03 | 1998-03-05 | Basf Ag | Feste geschäumte Wirkstoffzubereitungen |
TW474824B (en) | 1996-09-13 | 2002-02-01 | Basf Ag | The production of solid pharmaceutical forms |
DE19710213A1 (de) * | 1997-03-12 | 1998-09-17 | Basf Ag | Verfahren zur Herstellung von festen Kombinationsarzneiformen |
DE19733504A1 (de) * | 1997-08-01 | 1999-02-04 | Basf Ag | Langsam sinkende Pellets oder Granulate für die Fischzucht |
DE19753298A1 (de) | 1997-12-01 | 1999-06-02 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
AU8621398A (en) * | 1998-01-12 | 1999-07-26 | Buhler Ag | Method and device for capsulating active ingredients |
US6787157B1 (en) * | 1998-03-10 | 2004-09-07 | Abbott Laboratories | Multiphase active ingredient-containing formulations |
DE19812688A1 (de) | 1998-03-23 | 1999-09-30 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
AU741746B2 (en) | 1998-04-30 | 2001-12-06 | Basf Aktiengesellschaft | Retarding formulations of active substances used for plant protection |
DE19839276A1 (de) | 1998-08-28 | 2000-03-02 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
DE19840256A1 (de) | 1998-09-03 | 2000-03-09 | Basf Ag | Verfahren zur Herstellung von beschichteten festen Dosierungsformen |
DE19841244A1 (de) * | 1998-09-09 | 2000-03-16 | Knoll Ag | Verfahren und Vorrichtung zum Herstellen von Tabletten |
DE19842753A1 (de) | 1998-09-18 | 2000-03-23 | Bayer Ag | Agitationsunabhängige pharmazeutische Retardzubereitungen und Verfahren zu ihrer Herstellung |
DE19843904A1 (de) | 1998-09-24 | 2000-03-30 | Basf Ag | Feste Dosierungsform mit polymerem Bindemittel |
DE19847618A1 (de) | 1998-10-15 | 2000-04-20 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
DE19853985A1 (de) | 1998-11-23 | 2000-05-25 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
DE19901383A1 (de) | 1999-01-15 | 2000-07-20 | Knoll Ag | Verfahren zur Herstellung unterschiedlicher fester Dosierungsformen |
DE19913692A1 (de) | 1999-03-25 | 2000-09-28 | Basf Ag | Mechanisch stabile pharmazeutische Darreichungsformen, enthaltend flüssige oder halbfeste oberflächenaktive Substanzen |
DE19918325A1 (de) | 1999-04-22 | 2000-10-26 | Euro Celtique Sa | Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion |
ATE308897T1 (de) | 1999-09-06 | 2005-11-15 | Firmenich & Cie | Verfahren zur herstellung von granulaten für die kontrollierte freigabe der flüchtigen verbindungen |
DE19943501A1 (de) | 1999-09-10 | 2001-03-15 | Basf Ag | Unterwassergranulation wirkstoffhaltiger Schmelzen |
ATE266996T1 (de) * | 1999-10-13 | 2004-06-15 | Novo Nordisk As | Verfahren zum herstellung von medizinische formkörpern |
US7364752B1 (en) | 1999-11-12 | 2008-04-29 | Abbott Laboratories | Solid dispersion pharamaceutical formulations |
DE60028754T2 (de) | 1999-11-12 | 2007-05-31 | Abbott Laboratories, Abbott Park | Feste dispersion mit ritonavir, fenofibrat oder griseofulvin |
GB9927682D0 (en) * | 1999-11-23 | 2000-01-19 | Unilever Plc | Process for the manufacture of shaped articles |
DE10017102A1 (de) | 2000-04-06 | 2001-10-11 | Basf Ag | Verfahren zur Herstellung von festen Kreatin-Dosierungsformen und dadurch erhältliche Dosierungsformen |
GB0008553D0 (en) * | 2000-04-06 | 2000-05-24 | Unilever Plc | Process and apparatus for the production of a detergent bar |
DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
DE10038571A1 (de) * | 2000-08-03 | 2002-02-14 | Knoll Ag | Zusammensetzungen und Dosierungsformen zur Anwendung in der Mundhöhle bei der Bhandlung von Mykosen |
DE10046541A1 (de) * | 2000-09-19 | 2002-03-28 | Knoll Ag | Mechanisch stabile darreichungsformen, enthaltend Ubichinone |
US6767619B2 (en) * | 2001-05-17 | 2004-07-27 | Charles R. Owens | Preform for manufacturing a material having a plurality of voids and method of making the same |
GB0113841D0 (en) * | 2001-06-07 | 2001-08-01 | Boots Co Plc | Therapeutic agents |
US20030203027A1 (en) * | 2002-04-26 | 2003-10-30 | Ethicon, Inc. | Coating technique for deposition of drug substance on a substrate |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE10247037A1 (de) * | 2002-10-09 | 2004-04-22 | Abbott Gmbh & Co. Kg | Herstellung von festen Dosierungsformen unter Verwendung eines vernetzten nichtthermoplastischen Trägers |
US6797213B2 (en) * | 2002-10-15 | 2004-09-28 | Frito-Lay North America, Inc | Method and apparatus for producing a curly puff extrudate |
WO2004054568A1 (en) * | 2002-12-17 | 2004-07-01 | Abbott Gmbh & Co. Kg | Formulation comprising fenofibric acid, a physiologically acceptable salt or derivative thereof |
US20080051411A1 (en) * | 2002-12-17 | 2008-02-28 | Cink Russell D | Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof |
US7423004B2 (en) * | 2003-01-31 | 2008-09-09 | Smithkline Beecham Corporation | Solid dispersion compositions |
US9579286B2 (en) | 2003-04-21 | 2017-02-28 | Purdue Pharma L.P. | Tamper resistant dosage form comprising co-extruded, sequestered adverse agent particles and process of making same |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
US8883204B2 (en) | 2003-12-09 | 2014-11-11 | Purdue Pharma L.P. | Tamper resistant co-extruded dosage form containing an active agent and an adverse agent and process of making same |
DE602004005076T2 (de) * | 2003-12-09 | 2007-11-15 | Euro-Celtique S.A. | Co-extrudierte sicherheits-dosierform mit einem wirkstoff und einem adversen mittel und herstellungsverfahren dafür |
GB2409204A (en) * | 2003-12-19 | 2005-06-22 | Reckitt Benckiser Nv | Plasticized thermoplastic polymer |
PL1748762T3 (pl) | 2004-05-28 | 2014-05-30 | Abbvie Deutschland | Postać dawkowania, dająca się otrzymać ze sproszkowanej mieszaniny zawierającej nieorganiczny pigment |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102005005449A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US20090220596A1 (en) * | 2005-07-05 | 2009-09-03 | Abbott Gmbh & Co. Kg | Composition and Dosage Form Comprising a Solid or Semi-Solid Matrix |
EP1912626B1 (en) * | 2005-08-08 | 2016-04-13 | AbbVie Deutschland GmbH & Co KG | Dosage forms with improved bioavailability |
EP1912625B1 (en) | 2005-08-08 | 2016-04-13 | AbbVie Deutschland GmbH & Co KG | Itraconazole compositions with improved bioavailability |
EP1832281A1 (en) * | 2006-03-10 | 2007-09-12 | Abbott GmbH & Co. KG | Process for producing a solid dispersion of an active ingredient |
US7850894B2 (en) * | 2006-05-04 | 2010-12-14 | Ethicon, Inc. | Tissue holding devices and methods for making the same |
EP1925441A1 (de) | 2006-11-24 | 2008-05-28 | Abbott GmbH & Co. KG | Vorrichtung und Verfahren zum Bilden von Formlingen aus einer formbaren Masse |
EP1925442A1 (de) | 2006-11-24 | 2008-05-28 | Abbott GmbH & Co. KG | Hochleistungs-Rotationsumlauf-Form-Verfahren und -Vorrichtung |
DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
US8562644B2 (en) * | 2007-08-06 | 2013-10-22 | Ethicon, Inc. | Barbed suture with non-symmetric barbs |
CA2700426C (en) * | 2007-09-25 | 2017-10-31 | Galia Temtsin Krayz | Compositions comprising lipophilic active compounds and method for their preparation |
BRPI0906467C1 (pt) | 2008-01-25 | 2021-05-25 | Gruenenthal Gmbh | forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada |
WO2009135680A1 (en) | 2008-05-09 | 2009-11-12 | Grünenthal GmbH | Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step |
CA2760744C (en) | 2009-03-26 | 2017-05-30 | Swiss Caps Rechte Und Lizenzen Ag | Method and device for producing soft capsules |
CN102639118B (zh) | 2009-07-22 | 2015-07-29 | 格吕伦塔尔有限公司 | 氧化稳定的抗干扰剂型 |
EP2456427B1 (en) | 2009-07-22 | 2015-03-04 | Grünenthal GmbH | Hot-melt extruded controlled release dosage form |
US9579285B2 (en) | 2010-02-03 | 2017-02-28 | Gruenenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of an extruder |
WO2012028318A1 (en) | 2010-09-02 | 2012-03-08 | Grünenthal GmbH | Tamper resistant dosage form comprising an anionic polymer |
EP2611426B1 (en) | 2010-09-02 | 2014-06-25 | Grünenthal GmbH | Tamper resistant dosage form comprising inorganic salt |
BR112013005195A2 (pt) | 2010-09-02 | 2016-07-12 | Gruenenthal Gmbh | forma de dosagem resistente à violação compreendendo um polímero aniônico |
EP2463327A3 (de) | 2010-12-10 | 2015-06-03 | Basf Se | Verfahren zur herstellung von granulaten, enthaltend mindestens eine wasserlösliche komponente |
SG191316A1 (en) | 2010-12-23 | 2013-07-31 | Abbott Gmbh & Co Kg | Solid retard formulations based on solid dispersions |
DK2736495T3 (da) | 2011-07-29 | 2017-11-13 | Gruenenthal Gmbh | Misbrugsbestandig tablet som tilvejebringer øjeblikkelig frigivelse af lægemiddel |
HUE034710T2 (hu) | 2011-07-29 | 2018-02-28 | Gruenenthal Gmbh | Visszaéléssel szemben ellenálló, azonnali hatóanyagfelszabadulást biztosító tabletta |
KR101274387B1 (ko) * | 2011-09-03 | 2013-06-17 | 김경란 | 구형물 성형장치 |
KR101437423B1 (ko) * | 2011-12-21 | 2014-09-11 | 권오익 | 다공판이 구비된 환 제조장치 |
CA2864949A1 (en) | 2012-02-28 | 2013-09-06 | Grunenthal Gmbh | Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer |
WO2013156453A1 (en) | 2012-04-18 | 2013-10-24 | Grünenthal GmbH | Tamper resistant and dose-dumping resistant pharmaceutical dosage form |
DK2846835T3 (en) | 2012-05-11 | 2017-12-04 | Gruenenthal Gmbh | Thermoformed, tamper-proof pharmaceutical dosage form containing zinc |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
CN103478878A (zh) * | 2012-06-12 | 2014-01-01 | 昆山市张浦镇合通网络科技服务部 | 简易快捷制块机 |
DE102013003032A1 (de) * | 2013-02-22 | 2014-09-25 | Automatik Plastics Machinery Gmbh | Quetschwalzengranulator und Verwendung desselben |
WO2014139803A1 (en) * | 2013-03-15 | 2014-09-18 | AbbVie Deutschland GmbH & Co. KG | Process and apparatus for metering a plasticized formulation |
EP3003279A1 (en) | 2013-05-29 | 2016-04-13 | Grünenthal GmbH | Tamper-resistant dosage form containing one or more particles |
AU2014273226B2 (en) | 2013-05-29 | 2019-06-27 | Grunenthal Gmbh | Tamper resistant dosage form with bimodal release profile |
KR20160031526A (ko) | 2013-07-12 | 2016-03-22 | 그뤼넨탈 게엠베하 | 에틸렌-비닐 아세테이트 중합체를 함유하는 템퍼 내성 투여형 |
EP3073994A1 (en) | 2013-11-26 | 2016-10-05 | Grünenthal GmbH | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
US20150164807A1 (en) | 2013-12-16 | 2015-06-18 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile manufactured by co-extrusion |
AU2015261060A1 (en) | 2014-05-12 | 2016-11-03 | Grunenthal Gmbh | Tamper resistant immediate release capsule formulation comprising Tapentadol |
CN106456550A (zh) | 2014-05-26 | 2017-02-22 | 格吕伦塔尔有限公司 | 避免乙醇剂量倾泻的多颗粒 |
DE202014008800U1 (de) * | 2014-11-05 | 2014-11-17 | Automatik Plastics Machinery Gmbh | Quetschwalzengranulator mit Quetschwalzenpaar und Verwendung desselben |
CA2975653A1 (en) | 2015-02-03 | 2016-08-11 | Grunenthal Gmbh | Tamper-resistant dosage form comprising a polyethylene glycol graft copolymer |
CA2983642A1 (en) | 2015-04-24 | 2016-10-27 | Grunenthal Gmbh | Tamper-resistant dosage form with immediate release and resistance against solvent extraction |
US10842750B2 (en) | 2015-09-10 | 2020-11-24 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
JP2017137279A (ja) * | 2016-02-04 | 2017-08-10 | 秀介 大友 | 連結状態で一個ずつ又は複数個ずつ自由に分割できる錠剤 |
CA3032598A1 (en) | 2016-08-01 | 2018-02-08 | Grunenthal Gmbh | Tamper resistant dosage form comprising an anionic polysaccharide |
CN107714654A (zh) * | 2016-08-11 | 2018-02-23 | 董玲 | 一种冻干制剂及其制备方法 |
BR112019002789A2 (pt) | 2016-08-12 | 2019-05-21 | Grünenthal GmbH | formulação de efedrina resistente à adulteração e seus derivados |
BE1024283B1 (fr) * | 2016-10-10 | 2018-01-12 | Universite De Liege | Appareillage pour la production en continu de formes orales solides |
CN106827289A (zh) * | 2017-03-28 | 2017-06-13 | 洛阳欧祺精密零件制造有限公司 | 一种造粒机 |
TW202002957A (zh) | 2018-02-09 | 2020-01-16 | 德商歌林達有限公司 | 包含轉化抑制劑之麻黃素及其衍生物之抗損壞調配物 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US99083A (en) * | 1870-01-25 | Improvement in moulding and glazing forms made of plastic material | ||
FR537444A (fr) * | 1920-11-24 | 1922-05-23 | Machine pour la fabrication des cachets pharmaceutiques | |
US2988774A (en) * | 1957-07-22 | 1961-06-20 | Lever Brothers Ltd | Method and apparatus for the production of soap tablets |
DE1766546C3 (de) * | 1968-06-11 | 1974-11-28 | Karl Gunnar Lidingoe Eriksson | Verfahren zum Herstellen von festen dragee- oder tablettenförmigen Arzneimittelzubereitungen |
US3755527A (en) * | 1969-10-09 | 1973-08-28 | Exxon Research Engineering Co | Process for producing melt blown nonwoven synthetic polymer mat having high tear resistance |
BE795766A (fr) * | 1972-02-22 | 1973-08-22 | Lilly Co Eli | Particules de napsylate de propoxyphene retard et procede de fabrication de ces particules |
US3859407A (en) * | 1972-05-15 | 1975-01-07 | Corning Glass Works | Method of manufacturing particles of uniform size and shape |
DE2241616C3 (de) * | 1972-08-24 | 1978-07-13 | Buss Ag, Basel (Schweiz) | Verfahren und Vorrichtung zur Aufbereitung von Polyadditionsharzzwischenprodukten |
US3843299A (en) * | 1972-09-01 | 1974-10-22 | V Minchenko | Device for shaping spherical pellets |
US4028024A (en) * | 1974-10-31 | 1977-06-07 | Moreland Stephen T | Manufacture of filled capsules or the like |
IT1065137B (it) * | 1976-08-05 | 1985-02-25 | Sir Soc Italiana Resine Spa | Composizioni da stampaggio comprendenti una resina fenolica novolacca e procedimento per la loro preparazione |
US4130521A (en) * | 1977-04-25 | 1978-12-19 | Chevron Research Company | Densification of polypyrrolidone |
US4256448A (en) * | 1978-03-09 | 1981-03-17 | Usm Corporation | Roller die |
AU525847B2 (en) * | 1978-03-09 | 1982-12-02 | Usm Corp. | Roller die 0 |
US4165978A (en) * | 1978-07-14 | 1979-08-28 | Midrex Corporation | Briquet sheet breaking by cooling and bending |
JPS56160900A (en) * | 1980-05-16 | 1981-12-10 | Mitsubishi Heavy Ind Ltd | Briquette machine |
US4340557A (en) * | 1980-12-16 | 1982-07-20 | Ball Corporation | Method of making unfestooned plastic containers from polygonal blanks |
US4411161A (en) * | 1981-08-10 | 1983-10-25 | International Telephone & Telegraph Corporation | Mass flowmeter or the like |
US4451260A (en) * | 1982-03-26 | 1984-05-29 | Minnesota Mining And Manufacturing Company | Sustained release oral medicinal delivery device |
US4520180A (en) * | 1982-09-20 | 1985-05-28 | Gaf Corporation | Polymerization of vinylpyrrolidone to various molecular weights using a single initiator system consisting essentially of t-Butylperoxypivalate |
US4520179A (en) * | 1982-09-20 | 1985-05-28 | Gaf Corporation | Preparation of vinylpyrrolidone/vinyl acetate copolymers of various molecular weights using a single initiator system consisting essentially of t-Butylperoxypivalate |
JPS59222406A (ja) * | 1983-06-01 | 1984-12-14 | Teijin Ltd | 歯周疾患治療用製剤及びその製造法 |
DE3612212A1 (de) * | 1986-04-11 | 1987-10-15 | Basf Ag | Verfahren zur herstellung von festen pharmazeutischen formen |
-
1986
- 1986-04-11 DE DE19863612211 patent/DE3612211A1/de not_active Withdrawn
-
1987
- 1987-03-31 DE DE8787104731T patent/DE3769687D1/de not_active Expired - Lifetime
- 1987-03-31 EP EP87104731A patent/EP0240906B1/de not_active Expired - Lifetime
- 1987-03-31 ES ES87104731T patent/ES2022188B3/es not_active Expired - Lifetime
- 1987-03-31 AT AT87104731T patent/ATE63056T1/de not_active IP Right Cessation
- 1987-04-03 YU YU590/87A patent/YU45412B/xx unknown
- 1987-04-08 CS CS872531A patent/CS270222B2/cs not_active IP Right Cessation
- 1987-04-08 FI FI871538A patent/FI88577C/fi not_active IP Right Cessation
- 1987-04-09 AR AR87307264A patent/AR241630A1/es active
- 1987-04-09 JP JP62085890A patent/JPH078293B2/ja not_active Expired - Fee Related
- 1987-04-10 CA CA000534439A patent/CA1303501C/en not_active Expired - Lifetime
- 1987-04-10 PT PT84660A patent/PT84660B/pt not_active IP Right Cessation
- 1987-04-10 HU HU871623A patent/HUT55218A/hu unknown
- 1987-04-10 AU AU71400/87A patent/AU590697B2/en not_active Ceased
- 1987-04-10 NO NO871512A patent/NO173588C/no not_active IP Right Cessation
- 1987-04-11 CN CN87102755A patent/CN1056508C/zh not_active Expired - Lifetime
- 1987-04-11 KR KR1019870003528A patent/KR940005302B1/ko not_active IP Right Cessation
-
1988
- 1988-12-22 US US07/289,407 patent/US4880585A/en not_active Expired - Lifetime
-
1991
- 1991-06-03 GR GR91400710T patent/GR3002559T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
FI871538A (fi) | 1987-10-12 |
PT84660A (en) | 1987-05-01 |
NO173588C (no) | 1994-01-05 |
CN1056508C (zh) | 2000-09-20 |
AU7140087A (en) | 1987-10-15 |
DE3612211A1 (de) | 1987-10-15 |
ES2022188B3 (es) | 1991-12-01 |
FI871538A0 (fi) | 1987-04-08 |
KR870009705A (ko) | 1987-11-30 |
FI88577C (fi) | 1993-06-10 |
EP0240906B1 (de) | 1991-05-02 |
CA1303501C (en) | 1992-06-16 |
NO173588B (no) | 1993-09-27 |
EP0240906A2 (de) | 1987-10-14 |
AU590697B2 (en) | 1989-11-09 |
GR3002559T3 (en) | 1993-01-25 |
US4880585A (en) | 1989-11-14 |
YU59087A (en) | 1989-12-31 |
YU45412B (en) | 1992-05-28 |
CS270222B2 (en) | 1990-06-13 |
CS253187A2 (en) | 1989-10-13 |
HUT55218A (en) | 1991-05-28 |
EP0240906A3 (en) | 1988-08-03 |
KR940005302B1 (ko) | 1994-06-16 |
NO871512D0 (no) | 1987-04-10 |
JPH078293B2 (ja) | 1995-02-01 |
CN87102755A (zh) | 1987-10-28 |
DE3769687D1 (de) | 1991-06-06 |
FI88577B (fi) | 1993-02-26 |
ATE63056T1 (de) | 1991-05-15 |
JPS62240061A (ja) | 1987-10-20 |
NO871512L (no) | 1987-10-12 |
PT84660B (pt) | 1989-11-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR241630A1 (es) | Procedimiento continuo para la elaboracion de comprimidos de mezclas farmaceuticas y dispositivo para llevar a la practica dicho procedimiento. | |
IT1084072B (it) | Asciugamano a perdere in particolare per uso chirurgico e procedimento per la sua produzione | |
IT1078635B (it) | Dispositivo e procedimento per la produzione in continuo di miscele di materiali particellari a base di cemento e gesso | |
MX143112A (es) | Mejoras a un procedimiento para la fabricacion continua de plan chas de virutas que estan cubiertas con objetos planos y producto obtenido por dicho procedimiento | |
IT7850753A0 (it) | Pellicola decorativa metallizzata eprocedimento per la sua produzione | |
IT1089952B (it) | Catalizzatore e procedimento per la sua produzione | |
IT1038235B (it) | Piastra a struttura cellulare nonche procedimento per la sua fabbricazione | |
IT1059779B (it) | Miscuglio amminoalcanolico e procedimento per la sua produzione | |
ES504858A0 (es) | Un procedimiento y su correspondiente dispositivo para acelerar la disolucion de medicamentos liozilizados poco solu- bles a base de proteinas. | |
IT8048927A0 (it) | Prodotto isolante granulare e procedimento per la sua preparazione | |
IT1104163B (it) | Procedimento di compatta sotto pressione di miscela a base di gesso | |
IT1064004B (it) | Fotoricettore composito e procedimento per la sua produzione | |
FR2338118A1 (fr) | Presse hydraulique, particulierement pour moulage et pressage d'objets en ceramique creux tronconico-cylindriques, tronconiques ou similaires | |
IT1116851B (it) | Procedimento per la preparazione di antibiotici a base di beta-lattame e prodotto ottenuto | |
IT1105798B (it) | Procedimento per la produzione di compresse e pressa per compresse | |
IT7849155A0 (it) | Composizione farmaceutica a base difosfonati e procedimento per la sua applicazione | |
AR218047A1 (es) | Un procedimiento para obtener preparaciones farmaceuticas de liberacion continua prolongada | |
IT1059777B (it) | Miscuglio amminoalcanolico e procedimento per la sua produzione | |
ES529144A0 (es) | Procedimiento de fabricacion de productos celulares y de estratificados a base de prepolimeros furanicos anhidros | |
AR219501A1 (es) | Nuevos esteres y amidas-esteres ter-butilpirazolilicos de los acidos fosforico,tiono-,tiol-y tionotiolfosforico,fosfonicos y tionofosfonicos con propiedades insecticidas,acaricidas y nematodicidas,procedimiento para su produccion y composiciones insecticidas,acaricidas y nematodicidas a base de los mismos | |
IT1133080B (it) | Materiale per la produzione di fertilizzanti e procedimento per la sua preparazione ed impiego | |
IT1050492B (it) | Perborato sodico oranulare e procedimento per la sua fabbricazione | |
IT1019648B (it) | Laminato a base di policarbonato e procedimento per la sua prepara zione | |
IT1018644B (it) | Prodotto polimerico espanso e procedimento per la sua preparazione | |
IT1126275B (it) | Cemento e procedimento per la sua produzione |