GR1000358B - Μεθοδος για την παρασκευη φαρμακευτικων προσροφηματων. - Google Patents

Μεθοδος για την παρασκευη φαρμακευτικων προσροφηματων.

Info

Publication number
GR1000358B
GR1000358B GR890100314A GR890100314A GR1000358B GR 1000358 B GR1000358 B GR 1000358B GR 890100314 A GR890100314 A GR 890100314A GR 890100314 A GR890100314 A GR 890100314A GR 1000358 B GR1000358 B GR 1000358B
Authority
GR
Greece
Prior art keywords
absorbates
drug
preparation
aqueous
cocci
Prior art date
Application number
GR890100314A
Other languages
English (en)
Other versions
GR890100314A (en
Inventor
Ruth Fiona Bird
John Stephen Douglas
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888811167A external-priority patent/GB8811167D0/en
Priority claimed from GB888816185A external-priority patent/GB8816185D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of GR890100314A publication Critical patent/GR890100314A/el
Publication of GR1000358B publication Critical patent/GR1000358B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

Abstract

Η πικρή γεύση της ρανιτιδίνης μπορεί να καλυφθεί σχηματίζοντας ένα προσρόφημα με συνθετική κατιοανταλλακτική ρητίνη. Το προσρόφημα είναι ιδιαιτέρως κατάλληλο για χρήση σε φαρμακευτικές συνθέσεις για στοματική χορήγηση όπως δισκία που μασώνται ή πιπιλίζονται, κόκοι και υδατικά ή μη υδατικά εναιωρήματα. ω
GR890100314A 1988-05-11 1989-05-10 Μεθοδος για την παρασκευη φαρμακευτικων προσροφηματων. GR1000358B (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888811167A GB8811167D0 (en) 1988-05-11 1988-05-11 Medicaments
GB888816185A GB8816185D0 (en) 1988-07-07 1988-07-07 Medicaments

Publications (2)

Publication Number Publication Date
GR890100314A GR890100314A (en) 1990-03-12
GR1000358B true GR1000358B (el) 1992-06-30

Family

ID=26293879

Family Applications (1)

Application Number Title Priority Date Filing Date
GR890100314A GR1000358B (el) 1988-05-11 1989-05-10 Μεθοδος για την παρασκευη φαρμακευτικων προσροφηματων.

Country Status (35)

Country Link
US (1) US5032393A (el)
JP (1) JP2944678B2 (el)
KR (1) KR890016968A (el)
CN (1) CN1027133C (el)
AT (1) AT401614B (el)
AU (1) AU624613B2 (el)
BE (1) BE1002159A5 (el)
CA (1) CA1337272C (el)
CH (1) CH679011A5 (el)
CY (1) CY1781A (el)
DE (1) DE3915347C2 (el)
DK (1) DK168934B1 (el)
ES (1) ES2011573A6 (el)
FI (1) FI92060C (el)
FR (1) FR2631232B1 (el)
GB (1) GB2218333B (el)
GR (1) GR1000358B (el)
HK (1) HK45094A (el)
HU (2) HU204994B (el)
IE (1) IE60722B1 (el)
IL (1) IL90245A (el)
IT (1) IT1232831B (el)
LU (1) LU87515A1 (el)
MX (1) MX173349B (el)
MY (1) MY104013A (el)
NL (1) NL8901188A (el)
NO (1) NO175131C (el)
NZ (1) NZ229064A (el)
PH (1) PH27612A (el)
PL (1) PL279377A1 (el)
PT (1) PT90523B (el)
RU (1) RU2033155C1 (el)
SE (1) SE508343C2 (el)
SG (1) SG48194G (el)
YU (1) YU47674B (el)

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EP0620001A1 (en) * 1993-04-16 1994-10-19 McNEIL-PPC, INC. Aqueous pharmaceutical suspension and process for preparation thereof
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US5980882A (en) * 1997-04-16 1999-11-09 Medeva Pharmaceuticals Manufacturing Drug-resin complexes stabilized by chelating agents
JP4283355B2 (ja) * 1997-11-10 2009-06-24 久光製薬株式会社 薬剤用徐放化剤及びそれを含有した徐放性医薬組成物
CA2309597A1 (en) 1997-11-10 1999-05-20 Hiroshi Sorimachi Sustainedly releasing agents for medicines and sustainedly released medicinal compositions containing the same
ATE411047T1 (de) * 1999-07-14 2008-10-15 Schering Plough Ltd Maskieren des geschmacks der oralen flüssigen chinolon-zubereitungen mit ionenaustauscherharzen
US6514492B1 (en) 1999-07-14 2003-02-04 Schering-Plough Veterinary Corporation Taste masking of oral quinolone liquid preparations using ion exchange resins
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ATE396746T1 (de) * 2002-01-18 2008-06-15 Rohm & Haas Verwendung eines resinats zur herstellung einer formulierung zur beendigung des rauchens
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
US20050142097A1 (en) * 2003-12-29 2005-06-30 Deepak Thassu Multiple active drug resin conjugate
WO2007001300A1 (en) * 2005-06-28 2007-01-04 Ucb, S.A. Multiple active drug-resin conjugate
US20050265955A1 (en) * 2004-05-28 2005-12-01 Mallinckrodt Inc. Sustained release preparations
EP1926736A4 (en) * 2005-09-21 2010-08-25 Chong Kun Dang Pharm Corp NEW RESINATE COMPLEX OF S-CLOPIDOGREL AND METHOD FOR THE PRODUCTION THEREOF
EP2018160B1 (en) 2006-03-16 2011-12-14 Tris Pharma, Inc. Modified release formulations containing drug-ion exchange resin complexes
CN100411626C (zh) * 2006-08-28 2008-08-20 浙江大学 缓释型碘补充剂的制备方法
US8287848B2 (en) 2006-10-03 2012-10-16 Tris Pharma Inc Formulations containing an ionic mineral-ion exchange resin complex and uses thereof
CN100450548C (zh) * 2006-12-22 2009-01-14 江苏奥赛康药业有限公司 一种波拉克林树脂组合物的口腔贴片及其制备方法
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WO2009102830A1 (en) * 2008-02-13 2009-08-20 Eurand Inc Orally disintegrating tablet compositions of ranitidine and methods of manufacture
JP5560701B2 (ja) * 2008-12-26 2014-07-30 ライオン株式会社 ラニチジン含有医薬固形製剤及びラニチジン担持粒子の製造方法
JP5412966B2 (ja) * 2009-06-08 2014-02-12 ライオン株式会社 粒状製剤
US8357398B2 (en) * 2009-10-21 2013-01-22 Alitair Pharmaceuticals Inc. Benzonatate compositions and methods of use
CN102198118B (zh) * 2011-03-28 2012-08-29 于晓勇 一种治疗呕吐的口腔药物制剂及其制备方法
CN102138915A (zh) * 2011-03-28 2011-08-03 于晓勇 一种口服药物制剂及其制备方法
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Also Published As

Publication number Publication date
FI892248A0 (fi) 1989-05-10
NO891906D0 (no) 1989-05-10
NZ229064A (en) 1991-12-23
NO175131C (no) 1994-09-07
IT1232831B (it) 1992-03-05
SE8901671D0 (sv) 1989-05-10
IL90245A (en) 1994-04-12
PT90523B (pt) 1994-10-31
HK45094A (en) 1994-05-13
DE3915347A1 (de) 1989-11-16
IL90245A0 (en) 1989-12-15
YU97189A (en) 1990-06-30
FI92060B (fi) 1994-06-15
CN1027133C (zh) 1994-12-28
DK168934B1 (da) 1994-07-11
CH679011A5 (el) 1991-12-13
SE8901671L (sv) 1989-11-12
ES2011573A6 (es) 1990-01-16
FI92060C (fi) 1994-09-26
GB2218333A (en) 1989-11-15
HUT50036A (en) 1989-12-28
KR890016968A (ko) 1989-12-14
ATA112089A (de) 1996-03-15
US5032393A (en) 1991-07-16
CY1781A (en) 1995-10-20
PT90523A (pt) 1989-11-30
AU3461789A (en) 1989-11-16
RU2033155C1 (ru) 1995-04-20
IE60722B1 (en) 1994-08-10
CN1037651A (zh) 1989-12-06
GB2218333B (en) 1991-11-06
BE1002159A5 (fr) 1990-08-14
SG48194G (en) 1994-11-25
MX15983A (es) 1993-10-01
AT401614B (de) 1996-10-25
DK229489A (da) 1989-11-12
FR2631232B1 (fr) 1993-11-19
AU624613B2 (en) 1992-06-18
MX173349B (es) 1994-01-22
SE508343C2 (sv) 1998-09-28
JP2944678B2 (ja) 1999-09-06
PH27612A (en) 1993-08-31
YU47674B (sh) 1996-01-08
NO891906L (no) 1989-11-13
NL8901188A (nl) 1989-12-01
PL279377A1 (en) 1990-01-22
IT8947938A0 (it) 1989-05-10
GR890100314A (en) 1990-03-12
GB8910706D0 (en) 1989-06-28
IE891527L (en) 1989-11-11
DK229489D0 (da) 1989-05-10
CA1337272C (en) 1995-10-10
FR2631232A1 (fr) 1989-11-17
LU87515A1 (fr) 1990-06-12
HU211592A9 (en) 1995-12-28
DE3915347C2 (de) 1994-11-03
FI892248A (fi) 1989-11-12
HU204994B (en) 1992-03-30
NO175131B (no) 1994-05-30
JPH02111719A (ja) 1990-04-24
MY104013A (en) 1993-10-30

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