IT1060117B - 4 alchil diossi alchilen 5 benzil pirimidine, procedimento per la loro preparazione e preparati medicinali - Google Patents
4 alchil diossi alchilen 5 benzil pirimidine, procedimento per la loro preparazione e preparati medicinaliInfo
- Publication number
- IT1060117B IT1060117B IT12623/74A IT1262374A IT1060117B IT 1060117 B IT1060117 B IT 1060117B IT 12623/74 A IT12623/74 A IT 12623/74A IT 1262374 A IT1262374 A IT 1262374A IT 1060117 B IT1060117 B IT 1060117B
- Authority
- IT
- Italy
- Prior art keywords
- diossi
- alchilen
- alchil
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19732313361 DE2313361C3 (de) | 1973-03-17 | 2,4-Diamino-5-(3',5'-dimethoxy-4'-methoxyalkoxybenzyl-pyrimidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1060117B true IT1060117B (it) | 1982-07-10 |
Family
ID=5875077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT12623/74A IT1060117B (it) | 1973-03-17 | 1974-03-15 | 4 alchil diossi alchilen 5 benzil pirimidine, procedimento per la loro preparazione e preparati medicinali |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3992379A (it) |
| JP (1) | JPS584025B2 (it) |
| AR (1) | AR207561A1 (it) |
| AT (1) | AT338795B (it) |
| AU (1) | AU476979B2 (it) |
| BE (1) | BE812375A (it) |
| BR (1) | BR7401966D0 (it) |
| CA (1) | CA1063607A (it) |
| CH (1) | CH601257A5 (it) |
| ES (1) | ES424274A1 (it) |
| FR (1) | FR2221147B1 (it) |
| GB (1) | GB1413454A (it) |
| HK (1) | HK50580A (it) |
| HU (1) | HU166864B (it) |
| IT (1) | IT1060117B (it) |
| NL (1) | NL175414C (it) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4115650A (en) * | 1976-11-17 | 1978-09-19 | Hoffmann-La Roche Inc. | Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines |
| US4103902A (en) * | 1977-08-16 | 1978-08-01 | Foster Wheeler Energy Corporation | Water seal for regenerator |
| US4258045A (en) * | 1979-11-30 | 1981-03-24 | Merck & Co., Inc. | Inhibitor of dihydrofolate reductase |
| ZA818204B (en) * | 1980-11-27 | 1983-07-27 | Wellcome Found | Antibacterial benzylpyrimidines |
| JPS60107889U (ja) * | 1983-12-20 | 1985-07-22 | トキコ株式会社 | 給油量表示装置 |
| DE3613794A1 (de) * | 1986-04-24 | 1987-10-29 | Frank Joachim Mueller | Verfahren zum nachweis von antibiotika- und sulfonamidrueckstaenden in biologischen fluessigkeiten oder nahrungsmitteln |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909522A (en) * | 1957-02-21 | 1959-10-20 | Burroughs Wellcome Co | Trialkoxybenzylpyrimidines and method |
| GB1142654A (en) * | 1965-10-28 | 1969-02-12 | Wellcome Found | Cyano-acetals and their use in benzylpyrimidine synthesis |
| GB1229413A (it) * | 1967-06-14 | 1971-04-21 | ||
| US3849407A (en) * | 1969-03-06 | 1974-11-19 | Burroughs Wellcome Co | 5-benzyl pyrimidines intermediates |
| US3819629A (en) * | 1970-02-10 | 1974-06-25 | Burroughs Wellcome Co | Method for preparing 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine |
| US3692787A (en) * | 1970-02-16 | 1972-09-19 | Burroughs Wellcome Co | Substituted 2,4-diamino-5-benzyl pyrimidines |
| US3772289A (en) * | 1970-10-22 | 1973-11-13 | Burroughs Wellcome Co | Alkyl substituted benzyl pyrimidines |
-
1974
- 1974-01-01 AR AR252792A patent/AR207561A1/es active
- 1974-03-11 CH CH338074A patent/CH601257A5/xx not_active IP Right Cessation
- 1974-03-11 HU HUHE652A patent/HU166864B/hu unknown
- 1974-03-12 GB GB1104974A patent/GB1413454A/en not_active Expired
- 1974-03-14 ES ES424274A patent/ES424274A1/es not_active Expired
- 1974-03-14 BR BR1966/74A patent/BR7401966D0/pt unknown
- 1974-03-14 NL NLAANVRAGE7403411,A patent/NL175414C/xx not_active IP Right Cessation
- 1974-03-15 FR FR7408868A patent/FR2221147B1/fr not_active Expired
- 1974-03-15 IT IT12623/74A patent/IT1060117B/it active
- 1974-03-15 AT AT215474A patent/AT338795B/de not_active IP Right Cessation
- 1974-03-15 AU AU66713/74A patent/AU476979B2/en not_active Expired
- 1974-03-15 BE BE142065A patent/BE812375A/xx not_active IP Right Cessation
- 1974-03-15 US US05/451,595 patent/US3992379A/en not_active Expired - Lifetime
- 1974-03-18 JP JP49030851A patent/JPS584025B2/ja not_active Expired
- 1974-03-18 CA CA195,276A patent/CA1063607A/en not_active Expired
-
1980
- 1980-09-04 HK HK505/80A patent/HK50580A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES424274A1 (es) | 1976-11-01 |
| DE2313361A1 (de) | 1975-02-06 |
| BR7401966D0 (pt) | 1974-11-05 |
| US3992379A (en) | 1976-11-16 |
| NL7403411A (it) | 1974-09-19 |
| FR2221147A1 (it) | 1974-10-11 |
| AR207561A1 (es) | 1976-10-15 |
| DE2313361B2 (de) | 1975-07-10 |
| AU476979B2 (en) | 1976-10-07 |
| HU166864B (it) | 1975-06-28 |
| CA1063607A (en) | 1979-10-02 |
| ATA215474A (de) | 1977-01-15 |
| HK50580A (en) | 1980-09-12 |
| NL175414C (nl) | 1984-11-01 |
| AT338795B (de) | 1977-09-12 |
| BE812375A (fr) | 1974-07-01 |
| NL175414B (nl) | 1984-06-01 |
| CH601257A5 (it) | 1978-06-30 |
| FR2221147B1 (it) | 1982-06-11 |
| JPS5035176A (it) | 1975-04-03 |
| JPS584025B2 (ja) | 1983-01-24 |
| AU6671374A (en) | 1975-09-18 |
| GB1413454A (en) | 1975-11-12 |
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