GEP20186921B - Pyrazolopyridines and pyrazolopyrimidines - Google Patents

Pyrazolopyridines and pyrazolopyrimidines

Info

Publication number
GEP20186921B
GEP20186921B GEAP201514322A GEAP2015014322A GEP20186921B GE P20186921 B GEP20186921 B GE P20186921B GE AP201514322 A GEAP201514322 A GE AP201514322A GE AP2015014322 A GEAP2015014322 A GE AP2015014322A GE P20186921 B GEP20186921 B GE P20186921B
Authority
GE
Georgia
Prior art keywords
pyrazolopyridines
pyrazolopyrimidines
compounds
formula
pharmaceutically acceptable
Prior art date
Application number
GEAP201514322A
Other languages
English (en)
Inventor
Inc Pfizer
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53264695&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GEP20186921(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of GEP20186921B publication Critical patent/GEP20186921B/en

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
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    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D487/04—Ortho-condensed systems

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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
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GEAP201514322A 2014-05-14 2015-04-30 Pyrazolopyridines and pyrazolopyrimidines GEP20186921B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461993138P 2014-05-14 2014-05-14

Publications (1)

Publication Number Publication Date
GEP20186921B true GEP20186921B (en) 2018-11-12

Family

ID=53264695

Family Applications (2)

Application Number Title Priority Date Filing Date
GEAP201514322A GEP20186921B (en) 2014-05-14 2015-04-30 Pyrazolopyridines and pyrazolopyrimidines
GEAP201814322A GEAP201814322A (en) 2014-05-14 2015-04-30 Pyrazolopyridines and pyrazolopyrimidines

Family Applications After (1)

Application Number Title Priority Date Filing Date
GEAP201814322A GEAP201814322A (en) 2014-05-14 2015-04-30 Pyrazolopyridines and pyrazolopyrimidines

Country Status (29)

Country Link
US (2) US9518052B2 (enExample)
EP (1) EP3143021B1 (enExample)
JP (1) JP6663857B2 (enExample)
KR (1) KR20170002623A (enExample)
CN (1) CN106459048A (enExample)
AP (1) AP2016009562A0 (enExample)
AR (1) AR100438A1 (enExample)
AU (1) AU2015260905A1 (enExample)
CA (1) CA2948587C (enExample)
CL (1) CL2016002888A1 (enExample)
CR (1) CR20160525A (enExample)
CU (1) CU20160167A7 (enExample)
DO (1) DOP2016000298A (enExample)
EA (1) EA201650029A1 (enExample)
EC (1) ECSP16087271A (enExample)
ES (1) ES2737696T3 (enExample)
GE (2) GEP20186921B (enExample)
IL (1) IL248970A0 (enExample)
MD (1) MD20160121A2 (enExample)
MX (1) MX2016014878A (enExample)
NI (1) NI201600170A (enExample)
PE (1) PE20161475A1 (enExample)
PH (1) PH12016502228A1 (enExample)
SG (1) SG11201609139WA (enExample)
SV (1) SV2016005318A (enExample)
TN (1) TN2016000503A1 (enExample)
TW (1) TWI591067B (enExample)
UY (1) UY36121A (enExample)
WO (1) WO2015173683A1 (enExample)

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* Cited by examiner, † Cited by third party
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US9403810B2 (en) 2014-05-14 2016-08-02 Novartis Ag Carboxamide derivatives
EP3143021B1 (en) 2014-05-14 2019-06-12 Pfizer Inc Pyrazolopyridines and pyrazolopyrimidines
EP3371184A1 (en) 2015-11-03 2018-09-12 Topivert Pharma Limited 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as janus kinase inhibitors
KR20180073687A (ko) 2015-11-03 2018-07-02 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 호흡기 질환의 치료를 위한 jak 키나제 저해제 화합물
ES2840650T3 (es) 2015-11-03 2021-07-07 Topivert Pharma Ltd Derivados de 4,5,6,7-tetrahidro-1h-imidazo[4,5-c]piridina y 1,4,5,6,7,8-hexahidroimidazo[4,5-d]azepina como inhibidores de la quinasa janus
EA037748B1 (ru) 2017-03-09 2021-05-18 ТЕРЕВАНС БАЙОФАРМА Ар энд Ди АйПи, ЭлЭлСи Конденсированные имидазо-пиперидиновые ингибиторы jak
AR111495A1 (es) 2017-05-01 2019-07-17 Theravance Biopharma R&D Ip Llc Compuestos de imidazo-piperidina fusionada como inhibidores de jak
MY200348A (en) 2017-05-01 2023-12-21 Theravance Biopharma R&D Ip Llc Crystalline forms of a jak inhibitor compound
SG11201909019SA (en) 2017-05-01 2019-10-30 Theravance Biopharma R&D Ip Llc Methods of treatment using a jak inhibitor compound
US10392368B2 (en) 2017-08-01 2019-08-27 Theravance Biopharma R&D Ip, Llc Pyrazolo and triazolo bicyclic compounds as JAK kinase inhibitors
BR112020008850A2 (pt) 2017-11-03 2020-10-20 Aclaris Therapeutics, Inc. composto, composição farmacêutica e método para tratar uma doença mediada por jak1 e jak3
CN112823005B (zh) 2018-08-10 2024-08-20 阿克拉瑞斯治疗股份有限公司 吡咯并嘧啶itk抑制剂
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