CL2016002888A1 - Compuestos derivados de pirazolopiridinas y pirazolopirimidinas; composicion farmacéutica y su uso como inhibidores selectivos de janus quinasas (jak) en el tratamiento de enfermedades como congestion nasal, asma, epoc, rinitis alergica, diabetes entre otras. - Google Patents

Compuestos derivados de pirazolopiridinas y pirazolopirimidinas; composicion farmacéutica y su uso como inhibidores selectivos de janus quinasas (jak) en el tratamiento de enfermedades como congestion nasal, asma, epoc, rinitis alergica, diabetes entre otras.

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Publication number
CL2016002888A1
CL2016002888A1 CL2016002888A CL2016002888A CL2016002888A1 CL 2016002888 A1 CL2016002888 A1 CL 2016002888A1 CL 2016002888 A CL2016002888 A CL 2016002888A CL 2016002888 A CL2016002888 A CL 2016002888A CL 2016002888 A1 CL2016002888 A1 CL 2016002888A1
Authority
CL
Chile
Prior art keywords
pyrazolopyridines
epoc
pyrazolopyrimidines
asthma
diabetes
Prior art date
Application number
CL2016002888A
Other languages
English (en)
Inventor
Christoph Martin Dehnhardt
Joseph Walter Strohbach
Jotham Wadsworth Coe
Peter Jones
Yogesh Anil Sabnis
Florian Michel Wakenhut
Gavin Alistair Whitlock
Original Assignee
Pfizer
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Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53264695&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2016002888(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of CL2016002888A1 publication Critical patent/CL2016002888A1/es

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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Abstract

Compuestos derivados de pirazolopiridinas y pirazolopirimidinas; composición farmacéutica y su uso como inhibidores selectivos de Janus quinasas para el tratamiento de enfermedades tales como congestión nasal, asma, epoc, rinitis alérgica, artritis, enfermedad cardiovascular, aterosclerosis, infarto de miocardio, trombosis, insuficiencia cardíaca congestiva, diabetes tipo 1 y 2, cáncer, fibrosis, obesidad, distrofia muscular, polimiositis, enfermedad de Alzheimer, enrojecimiento de la piel, eczema, psoriasis, dermatitis atópica y quemadura de sol.
CL2016002888A 2014-05-14 2016-11-14 Compuestos derivados de pirazolopiridinas y pirazolopirimidinas; composicion farmacéutica y su uso como inhibidores selectivos de janus quinasas (jak) en el tratamiento de enfermedades como congestion nasal, asma, epoc, rinitis alergica, diabetes entre otras. CL2016002888A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461993138P 2014-05-14 2014-05-14

Publications (1)

Publication Number Publication Date
CL2016002888A1 true CL2016002888A1 (es) 2017-05-12

Family

ID=53264695

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Application Number Title Priority Date Filing Date
CL2016002888A CL2016002888A1 (es) 2014-05-14 2016-11-14 Compuestos derivados de pirazolopiridinas y pirazolopirimidinas; composicion farmacéutica y su uso como inhibidores selectivos de janus quinasas (jak) en el tratamiento de enfermedades como congestion nasal, asma, epoc, rinitis alergica, diabetes entre otras.

Country Status (29)

Country Link
US (2) US9518052B2 (es)
EP (1) EP3143021B1 (es)
JP (1) JP6663857B2 (es)
KR (1) KR20170002623A (es)
CN (1) CN106459048A (es)
AP (1) AP2016009562A0 (es)
AR (1) AR100438A1 (es)
AU (1) AU2015260905A1 (es)
CA (1) CA2948587C (es)
CL (1) CL2016002888A1 (es)
CR (1) CR20160525A (es)
CU (1) CU20160167A7 (es)
DO (1) DOP2016000298A (es)
EA (1) EA201650029A1 (es)
EC (1) ECSP16087271A (es)
ES (1) ES2737696T3 (es)
GE (1) GEP20186921B (es)
IL (1) IL248970A0 (es)
MD (1) MD20160121A2 (es)
MX (1) MX2016014878A (es)
NI (1) NI201600170A (es)
PE (1) PE20161475A1 (es)
PH (1) PH12016502228A1 (es)
SG (1) SG11201609139WA (es)
SV (1) SV2016005318A (es)
TN (1) TN2016000503A1 (es)
TW (1) TWI591067B (es)
UY (1) UY36121A (es)
WO (1) WO2015173683A1 (es)

Families Citing this family (32)

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WO2015173683A1 (en) 2014-05-14 2015-11-19 Pfizer Inc. Pyrazolopyridines and pyrazolopyrimidines
TWI714528B (zh) 2014-05-14 2021-01-01 瑞士商諾華公司 甲醯胺衍生物
EP3865481A1 (en) 2015-11-03 2021-08-18 Topivert Pharma Limited 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as janus kinase inhibitors
US10100049B2 (en) 2015-11-03 2018-10-16 Theravance Biopharma R&D Ip, Llc JAK kinase inhibitor compounds for treatment of respiratory disease
EP3371185B1 (en) 2015-11-03 2020-09-30 Topivert Pharma Limited 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as janus kinase inhibitors
ES2882186T3 (es) 2017-03-09 2021-12-01 Theravance Biopharma R&D Ip Llc Inhibidores de JAK que contienen una amida heterocíclica de 4 miembros
AU2018261591B2 (en) 2017-05-01 2021-09-02 Theravance Biopharma R&D Ip, Llc Crystalline forms of a JAK inhibitor compound
AR111495A1 (es) 2017-05-01 2019-07-17 Theravance Biopharma R&D Ip Llc Compuestos de imidazo-piperidina fusionada como inhibidores de jak
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