GEP19971025B - Process for producing lyophilizate - Google Patents
Process for producing lyophilizateInfo
- Publication number
- GEP19971025B GEP19971025B GEAP1993972A GEAP1993000972A GEP19971025B GE P19971025 B GEP19971025 B GE P19971025B GE AP1993972 A GEAP1993972 A GE AP1993972A GE AP1993000972 A GEAP1993000972 A GE AP1993000972A GE P19971025 B GEP19971025 B GE P19971025B
- Authority
- GE
- Georgia
- Prior art keywords
- lyophilizate
- water
- producing
- iphosphamide
- refrigerated
- Prior art date
Links
- HOMGKSMUEGBAAB-UHFFFAOYSA-N ifosfamide Chemical compound ClCCNP1(=O)OCCCN1CCCl HOMGKSMUEGBAAB-UHFFFAOYSA-N 0.000 abstract 3
- 229960001101 ifosfamide Drugs 0.000 abstract 3
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-UHFFFAOYSA-N hexane-1,2,3,4,5,6-hexol Chemical compound OCC(O)C(O)C(O)C(O)CO FBPFZTCFMRRESA-UHFFFAOYSA-N 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cephalosporin Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Amplifiers (AREA)
- Control Of El Displays (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3637089 | 1986-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GEP19971025B true GEP19971025B (en) | 1997-04-06 |
Family
ID=6312873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GEAP1993972A GEP19971025B (en) | 1986-10-31 | 1993-07-07 | Process for producing lyophilizate |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0265812B1 (forum.php) |
| JP (1) | JPS63159319A (forum.php) |
| KR (1) | KR900003491B1 (forum.php) |
| AT (1) | ATE55250T1 (forum.php) |
| AU (1) | AU598602B2 (forum.php) |
| CA (1) | CA1314231C (forum.php) |
| DD (1) | DD262582A5 (forum.php) |
| DE (1) | DE3764235D1 (forum.php) |
| DK (1) | DK169308B1 (forum.php) |
| EG (1) | EG18333A (forum.php) |
| ES (1) | ES2017982B3 (forum.php) |
| FI (1) | FI87140C (forum.php) |
| GE (1) | GEP19971025B (forum.php) |
| GR (1) | GR3000708T3 (forum.php) |
| HU (1) | HU197987B (forum.php) |
| IL (1) | IL84312A (forum.php) |
| IN (1) | IN168119B (forum.php) |
| LV (1) | LV10051B (forum.php) |
| MX (1) | MX8958A (forum.php) |
| NO (1) | NO873860L (forum.php) |
| PT (1) | PT86032B (forum.php) |
| RU (1) | RU1836079C (forum.php) |
| UA (1) | UA11075A (forum.php) |
| YU (1) | YU197387A (forum.php) |
| ZA (1) | ZA878183B (forum.php) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE58900183D1 (de) * | 1988-03-19 | 1991-08-29 | Asta Pharma Ag | Ifosfamid-mesna-lyophilisat und verfahren zu dessen herstellung. |
| US5227373A (en) * | 1991-10-23 | 1993-07-13 | Bristol-Myers Squibb Co. | Lyophilized ifosfamide compositions |
| WO1995007083A1 (en) * | 1993-09-10 | 1995-03-16 | F.H. Faulding & Co. Limited | Ifosfamide lyophilisate composition |
| DE19529057B4 (de) * | 1995-08-08 | 2007-12-13 | Baxter Healthcare S.A. | Ifosfamid-Lyophilisat-Zubereitungen |
| EP1058547B1 (en) * | 1998-03-03 | 2005-11-23 | Shionogi & Co., Ltd. | Pharmaceutical compositions containing the phospholipase inhibitor sodium 3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-phenylmethyl)-1h-indol-4-yl]oxy]acetate |
| EA008776B1 (ru) * | 2002-09-05 | 2007-08-31 | Бхарат Сирумс Энд Вэксинс Лтд. | Жидкая стабильная композиция оксазафосфорина с месной |
| BR0316968A (pt) * | 2002-12-02 | 2005-10-25 | Bharat Serums & Vaccines Ltd | Composições estáveis, claras, aquosas de ifosfamida para administração parenteral que apresentam pouca toxicidade; processo para a preparação de composições de ifosfamida; e composições de ifosfamida e um processo para a preparação das mesmas |
| US8436190B2 (en) * | 2005-01-14 | 2013-05-07 | Cephalon, Inc. | Bendamustine pharmaceutical compositions |
| BRPI0715279A2 (pt) * | 2006-09-29 | 2013-06-11 | Infa Sa | sistema de embalagem, sistema de embalagem para uma composiÇço farmacÊutica, mÉtodo para transferir uma composiÇço farmcÊutica para administraÇço por infusço intravenosa, uso de um sistema de embalagem, kit para administraÇço parenteral de fÁrmacos com um acesso intravenoso e kit admnistraÇço parenteral de princÍpios ativos |
| CN105900385B (zh) * | 2014-12-04 | 2019-08-27 | 华为技术有限公司 | 在数据通信网中的负载分配 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3732340A (en) * | 1966-07-11 | 1973-05-08 | Asta Werke Ag Chem Fab | N',o-propylene phosphoric acid ester diamides |
| DE2750207A1 (de) * | 1977-05-09 | 1978-11-16 | Walton J Smith | Gefriergetrocknete zusammensetzungen, insbesondere gefriergetrocknete pharmazeutische praeparate und verfahren zu deren herstellung |
| DE3279834D1 (en) * | 1981-12-31 | 1989-08-31 | Asta Pharma Ag | 4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression |
| US4537883A (en) * | 1982-11-12 | 1985-08-27 | Mead Johnson & Company | Lyophilized cyclophosphamide |
-
1987
- 1987-09-15 NO NO873860A patent/NO873860L/no unknown
- 1987-10-20 EP EP87115322A patent/EP0265812B1/de not_active Expired - Lifetime
- 1987-10-20 DE DE8787115322T patent/DE3764235D1/de not_active Expired - Lifetime
- 1987-10-20 ES ES87115322T patent/ES2017982B3/es not_active Expired - Lifetime
- 1987-10-20 AT AT87115322T patent/ATE55250T1/de not_active IP Right Cessation
- 1987-10-23 MX MX895887A patent/MX8958A/es unknown
- 1987-10-26 IN IN837/CAL/87A patent/IN168119B/en unknown
- 1987-10-27 FI FI874727A patent/FI87140C/fi not_active IP Right Cessation
- 1987-10-28 EG EG61687A patent/EG18333A/xx active
- 1987-10-29 RU SU874203570A patent/RU1836079C/ru active
- 1987-10-29 JP JP62272002A patent/JPS63159319A/ja active Granted
- 1987-10-29 UA UA4203570A patent/UA11075A/uk unknown
- 1987-10-29 PT PT86032A patent/PT86032B/pt unknown
- 1987-10-29 IL IL84312A patent/IL84312A/xx not_active IP Right Cessation
- 1987-10-30 AU AU80529/87A patent/AU598602B2/en not_active Ceased
- 1987-10-30 HU HU874900A patent/HU197987B/hu unknown
- 1987-10-30 ZA ZA878183A patent/ZA878183B/xx unknown
- 1987-10-30 DK DK569687A patent/DK169308B1/da not_active IP Right Cessation
- 1987-10-30 CA CA000550706A patent/CA1314231C/en not_active Expired - Lifetime
- 1987-10-30 KR KR1019870012077A patent/KR900003491B1/ko not_active Expired
- 1987-10-30 DD DD87308471A patent/DD262582A5/de not_active IP Right Cessation
- 1987-10-30 YU YU01973/87A patent/YU197387A/xx unknown
-
1990
- 1990-08-09 GR GR90400533T patent/GR3000708T3/el unknown
-
1992
- 1992-10-27 LV LVP-92-174A patent/LV10051B/lv unknown
-
1993
- 1993-07-07 GE GEAP1993972A patent/GEP19971025B/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT1209941B (it) | Procedimento di trattamento di cellule con proteine ossee solubili per renderle idonee a stimolare la crescita di tessuti cartilaginei ed ossei,e prodotto ottenuto | |
| ES8706391A1 (es) | Un procedimiento para la preparacion de una composicion tensoactiva en polvo que fluye libremente. | |
| EP0290616A4 (en) | POLYVINYL ALCOHOL GEL GAMMA STERILIZATION PROCESS. | |
| IT1131614B (it) | Procedimento per la produzione di pasta secca,impianto per la sua attuazione,nonche' prodotto ottenuto | |
| ES8307263A1 (es) | Un procedimiento para la preparacion de fosfonamidas sustituidas. | |
| GEP19971025B (en) | Process for producing lyophilizate | |
| PT80657B (en) | Process for preparing crystalline calcium pseudomonate or a hydrate thereof | |
| ZA915446B (en) | Growth hormone crystals and a process for production of these gh-crystals | |
| GR3002377T3 (en) | Ifosfamide-mesna-lyophilized composition and process to prepare it | |
| AU528098B2 (en) | Analgesic tablet | |
| DE3062352D1 (en) | Process for steeping corn, products so obtained and their use in the production of penicillin | |
| HUT52958A (en) | Process for production of medical compositions assuring the constant release of the active substance | |
| ES2026059A6 (es) | Procedimiento mejorado para la sintesis de 1-((1-(2-(trifluoreometil)-4-pirimidinil)-4-piperidinil)metil)-2-pirrolidinona. | |
| EP0225770A3 (en) | Producing fibrous food products | |
| GEP19960471B (en) | Method of producing n-sulfamine-3-(2-guanidinethiazol-4-ylmethylthio)-propioneamidine | |
| IT1158019B (it) | Procedimento fermentativo per la produzione di 9-idrossi-3-osso-4,17(20)-pregnadien-20-carbossaldeide e prodotto ottenuto, utile in particolare per la sintesi di corticosteroidi | |
| ES8606898A1 (es) | Un procedimiento para producir un factor regulador de cancerendogeno humano | |
| IL60108A0 (en) | Process for the manufacture of 5-mercapto-1,2,3-triazoles and novel 1,2,3-thiadiazole-5-carbohydroxamic acid derivatives | |
| ES8608315A1 (es) | Procedimiento para la obtencion de un somnifero conteniendo lorazepam | |
| ES8605518A1 (es) | Procedimiento para preparar derivados de 4-oxo-pirido(2,3-d)pirimidina | |
| BG60236B2 (en) | Process for producing of cyclic propylene ester of dihydropyridine-s-phosphonic acid | |
| HU178516B (en) | Process for producing enanthiomeres of 1-bracket-3,4-dimethoxy-phenyl-bracket closed-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine and pharmacologically acceptable soles of the /-/-enanthiomere | |
| BG47345A3 (en) | Method for preparing of dialkyloxalacetates | |
| DE3572171D1 (en) | Theophylline-7-acetic acid ester of d,l-trans-sobrerol having mucosecretolytic-fluidizing and antibronchospastic activity, a process for its preparation and pharmaceutical compositions thereof | |
| USD239559S (en) |