EG18333A - Process for preparing ifosphamide lyophilisate - Google Patents

Process for preparing ifosphamide lyophilisate

Info

Publication number
EG18333A
EG18333A EG61687A EG61687A EG18333A EG 18333 A EG18333 A EG 18333A EG 61687 A EG61687 A EG 61687A EG 61687 A EG61687 A EG 61687A EG 18333 A EG18333 A EG 18333A
Authority
EG
Egypt
Prior art keywords
ifosphamide
lyophilisate
preparing
ifosfamide
weight
Prior art date
Application number
EG61687A
Original Assignee
Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Ag filed Critical Pharma Ag
Application granted granted Critical
Publication of EG18333A publication Critical patent/EG18333A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

1. A lyophilized preparation consisting of ifosfamide and 0.1 to 17 parts by weight hexitol per part by weight ifosfamide and, optionally, other standard pharmaceutical auxiliaries.
EG61687A 1986-10-31 1987-10-28 Process for preparing ifosphamide lyophilisate EG18333A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3637089 1986-10-31

Publications (1)

Publication Number Publication Date
EG18333A true EG18333A (en) 1993-12-30

Family

ID=6312873

Family Applications (1)

Application Number Title Priority Date Filing Date
EG61687A EG18333A (en) 1986-10-31 1987-10-28 Process for preparing ifosphamide lyophilisate

Country Status (25)

Country Link
EP (1) EP0265812B1 (en)
JP (1) JPS63159319A (en)
KR (1) KR900003491B1 (en)
AT (1) ATE55250T1 (en)
AU (1) AU598602B2 (en)
CA (1) CA1314231C (en)
DD (1) DD262582A5 (en)
DE (1) DE3764235D1 (en)
DK (1) DK169308B1 (en)
EG (1) EG18333A (en)
ES (1) ES2017982B3 (en)
FI (1) FI87140C (en)
GE (1) GEP19971025B (en)
GR (1) GR3000708T3 (en)
HU (1) HU197987B (en)
IL (1) IL84312A (en)
IN (1) IN168119B (en)
LV (1) LV10051B (en)
MX (1) MX8958A (en)
NO (1) NO873860L (en)
PT (1) PT86032B (en)
RU (1) RU1836079C (en)
UA (1) UA11075A (en)
YU (1) YU197387A (en)
ZA (1) ZA878183B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE65402T1 (en) * 1988-03-19 1991-08-15 Asta Pharma Ag IFOSFAMIDE MESNA LYOPHILISATE AND PROCESS FOR PRODUCTION THEREOF.
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
WO1995007083A1 (en) * 1993-09-10 1995-03-16 F.H. Faulding & Co. Limited Ifosfamide lyophilisate composition
DE19529057B4 (en) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamide lyophilizate preparations
WO1999044604A1 (en) * 1998-03-03 1999-09-10 Shionogi & Co., Ltd. Pharmaceutical compositions containing the phospholipase inhibitor sodium [[3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-phenylmethyl)-1h-indol-4-yl]oxy]acetate
AU2003276689B2 (en) * 2002-09-05 2009-04-09 Bharat Serums And Vaccines Ltd. Liquid stable composition of oxazaphosphorine with mesna
ES2342380T3 (en) * 2002-12-02 2010-07-06 BHARAT SERUMS & VACCINES LTD. IFOSFAMIDE COMPOSITIONS FOR PARENTERAL ADMINISTRATION AND A PROCEDURE FOR PREPARATION.
US8436190B2 (en) * 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
DK2071917T3 (en) * 2006-09-29 2013-03-04 Infa Sa Packaging system for pharmaceutical compositions and kits for intravenous administration
WO2016087001A1 (en) * 2014-12-04 2016-06-09 Huawei Technologies Co., Ltd. Load allocation in a data communication network

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732340A (en) * 1966-07-11 1973-05-08 Asta Werke Ag Chem Fab N',o-propylene phosphoric acid ester diamides
DE2750207A1 (en) * 1977-05-09 1978-11-16 Walton J Smith Anhydrous compsn. prodn. by freeze drying hydrated, hydrolysable prod. - esp. aspirin or aspirin salt solns.
DE3279834D1 (en) * 1981-12-31 1989-08-31 Asta Pharma Ag 4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide

Also Published As

Publication number Publication date
FI87140C (en) 1992-12-10
HU197987B (en) 1989-07-28
LV10051A (en) 1994-05-10
PT86032A (en) 1987-11-01
JPH0543684B2 (en) 1993-07-02
IL84312A (en) 1991-11-21
YU197387A (en) 1988-12-31
IN168119B (en) 1991-02-09
AU598602B2 (en) 1990-06-28
ATE55250T1 (en) 1990-08-15
AU8052987A (en) 1988-05-05
CA1314231C (en) 1993-03-09
GR3000708T3 (en) 1991-10-10
MX8958A (en) 1993-12-01
GEP19971025B (en) 1997-04-06
IL84312A0 (en) 1988-03-31
DK169308B1 (en) 1994-10-10
HUT44932A (en) 1988-05-30
DK569687A (en) 1988-05-01
RU1836079C (en) 1993-08-23
FI874727A (en) 1988-05-01
FI87140B (en) 1992-08-31
ES2017982B3 (en) 1991-03-16
EP0265812B1 (en) 1990-08-08
NO873860D0 (en) 1987-09-15
ZA878183B (en) 1988-05-02
KR900003491B1 (en) 1990-05-21
DK569687D0 (en) 1987-10-30
UA11075A (en) 1996-12-25
DE3764235D1 (en) 1990-09-13
LV10051B (en) 1995-06-20
PT86032B (en) 1990-08-31
JPS63159319A (en) 1988-07-02
FI874727A0 (en) 1987-10-27
KR880004814A (en) 1988-06-27
EP0265812A1 (en) 1988-05-04
DD262582A5 (en) 1988-12-07
NO873860L (en) 1988-05-02

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