AU8052987A - Ifosphamide lyophilisate and process for its preparation - Google Patents

Ifosphamide lyophilisate and process for its preparation

Info

Publication number
AU8052987A
AU8052987A AU80529/87A AU8052987A AU8052987A AU 8052987 A AU8052987 A AU 8052987A AU 80529/87 A AU80529/87 A AU 80529/87A AU 8052987 A AU8052987 A AU 8052987A AU 8052987 A AU8052987 A AU 8052987A
Authority
AU
Australia
Prior art keywords
ifosphamide
lyophilisate
preparation
ifosfamide
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU80529/87A
Other versions
AU598602B2 (en
Inventor
Uwe-Peter Dammann
Otto Isaac
Dieter Sauerbier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Pharma AG filed Critical Asta Pharma AG
Publication of AU8052987A publication Critical patent/AU8052987A/en
Application granted granted Critical
Publication of AU598602B2 publication Critical patent/AU598602B2/en
Assigned to ASTA MEDICA AKTIENGESELLSCHAFT reassignment ASTA MEDICA AKTIENGESELLSCHAFT Request to Amend Deed and Register Assignors: ASTA-PHARMA AKTIENGESELLSCHAFT
Adjusted expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

1. A lyophilized preparation consisting of ifosfamide and 0.1 to 17 parts by weight hexitol per part by weight ifosfamide and, optionally, other standard pharmaceutical auxiliaries.
AU80529/87A 1986-10-31 1987-10-30 Ifosphamide lyophilisate and process for its preparation Ceased AU598602B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3637089 1986-10-31
DE3637089 1986-10-31

Publications (2)

Publication Number Publication Date
AU8052987A true AU8052987A (en) 1988-05-05
AU598602B2 AU598602B2 (en) 1990-06-28

Family

ID=6312873

Family Applications (1)

Application Number Title Priority Date Filing Date
AU80529/87A Ceased AU598602B2 (en) 1986-10-31 1987-10-30 Ifosphamide lyophilisate and process for its preparation

Country Status (25)

Country Link
EP (1) EP0265812B1 (en)
JP (1) JPS63159319A (en)
KR (1) KR900003491B1 (en)
AT (1) ATE55250T1 (en)
AU (1) AU598602B2 (en)
CA (1) CA1314231C (en)
DD (1) DD262582A5 (en)
DE (1) DE3764235D1 (en)
DK (1) DK169308B1 (en)
EG (1) EG18333A (en)
ES (1) ES2017982B3 (en)
FI (1) FI87140C (en)
GE (1) GEP19971025B (en)
GR (1) GR3000708T3 (en)
HU (1) HU197987B (en)
IL (1) IL84312A (en)
IN (1) IN168119B (en)
LV (1) LV10051B (en)
MX (1) MX8958A (en)
NO (1) NO873860L (en)
PT (1) PT86032B (en)
RU (1) RU1836079C (en)
UA (1) UA11075A (en)
YU (1) YU197387A (en)
ZA (1) ZA878183B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007083A1 (en) * 1993-09-10 1995-03-16 F.H. Faulding & Co. Limited Ifosfamide lyophilisate composition

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE65402T1 (en) * 1988-03-19 1991-08-15 Asta Pharma Ag IFOSFAMIDE MESNA LYOPHILISATE AND PROCESS FOR PRODUCTION THEREOF.
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
DE19529057B4 (en) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamide lyophilizate preparations
WO1999044604A1 (en) * 1998-03-03 1999-09-10 Shionogi & Co., Ltd. Pharmaceutical compositions containing the phospholipase inhibitor sodium [[3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-phenylmethyl)-1h-indol-4-yl]oxy]acetate
AU2003276689B2 (en) * 2002-09-05 2009-04-09 Bharat Serums And Vaccines Ltd. Liquid stable composition of oxazaphosphorine with mesna
ES2342380T3 (en) * 2002-12-02 2010-07-06 BHARAT SERUMS & VACCINES LTD. IFOSFAMIDE COMPOSITIONS FOR PARENTERAL ADMINISTRATION AND A PROCEDURE FOR PREPARATION.
US8436190B2 (en) * 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
DK2071917T3 (en) * 2006-09-29 2013-03-04 Infa Sa Packaging system for pharmaceutical compositions and kits for intravenous administration
WO2016087001A1 (en) * 2014-12-04 2016-06-09 Huawei Technologies Co., Ltd. Load allocation in a data communication network

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732340A (en) * 1966-07-11 1973-05-08 Asta Werke Ag Chem Fab N',o-propylene phosphoric acid ester diamides
DE2750207A1 (en) * 1977-05-09 1978-11-16 Walton J Smith Anhydrous compsn. prodn. by freeze drying hydrated, hydrolysable prod. - esp. aspirin or aspirin salt solns.
DE3279834D1 (en) * 1981-12-31 1989-08-31 Asta Pharma Ag 4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007083A1 (en) * 1993-09-10 1995-03-16 F.H. Faulding & Co. Limited Ifosfamide lyophilisate composition

Also Published As

Publication number Publication date
FI87140C (en) 1992-12-10
HU197987B (en) 1989-07-28
LV10051A (en) 1994-05-10
PT86032A (en) 1987-11-01
JPH0543684B2 (en) 1993-07-02
IL84312A (en) 1991-11-21
YU197387A (en) 1988-12-31
IN168119B (en) 1991-02-09
AU598602B2 (en) 1990-06-28
ATE55250T1 (en) 1990-08-15
EG18333A (en) 1993-12-30
CA1314231C (en) 1993-03-09
GR3000708T3 (en) 1991-10-10
MX8958A (en) 1993-12-01
GEP19971025B (en) 1997-04-06
IL84312A0 (en) 1988-03-31
DK169308B1 (en) 1994-10-10
HUT44932A (en) 1988-05-30
DK569687A (en) 1988-05-01
RU1836079C (en) 1993-08-23
FI874727A (en) 1988-05-01
FI87140B (en) 1992-08-31
ES2017982B3 (en) 1991-03-16
EP0265812B1 (en) 1990-08-08
NO873860D0 (en) 1987-09-15
ZA878183B (en) 1988-05-02
KR900003491B1 (en) 1990-05-21
DK569687D0 (en) 1987-10-30
UA11075A (en) 1996-12-25
DE3764235D1 (en) 1990-09-13
LV10051B (en) 1995-06-20
PT86032B (en) 1990-08-31
JPS63159319A (en) 1988-07-02
FI874727A0 (en) 1987-10-27
KR880004814A (en) 1988-06-27
EP0265812A1 (en) 1988-05-04
DD262582A5 (en) 1988-12-07
NO873860L (en) 1988-05-02

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Legal Events

Date Code Title Description
NDB Extension of term for standard patent granted (sect.76)

Free format text: 20121030