GB2058079B - Trh analogues - Google Patents
Trh analoguesInfo
- Publication number
- GB2058079B GB2058079B GB8021110A GB8021110A GB2058079B GB 2058079 B GB2058079 B GB 2058079B GB 8021110 A GB8021110 A GB 8021110A GB 8021110 A GB8021110 A GB 8021110A GB 2058079 B GB2058079 B GB 2058079B
- Authority
- GB
- United Kingdom
- Prior art keywords
- trh analogues
- trh
- analogues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06147—Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU79RI718A HU180926B (en) | 1979-06-28 | 1979-06-28 | Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2058079A GB2058079A (en) | 1981-04-08 |
| GB2058079B true GB2058079B (en) | 1983-03-02 |
Family
ID=11001101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8021110A Expired GB2058079B (en) | 1979-06-28 | 1980-06-27 | Trh analogues |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4386073A (enExample) |
| JP (1) | JPS568354A (enExample) |
| AT (1) | AT380259B (enExample) |
| AU (1) | AU538621B2 (enExample) |
| BE (1) | BE884015A (enExample) |
| BG (1) | BG60739B2 (enExample) |
| CA (1) | CA1188296A (enExample) |
| CH (1) | CH650519A5 (enExample) |
| CS (1) | CS241028B2 (enExample) |
| DD (1) | DD151745A5 (enExample) |
| DE (1) | DE3024256A1 (enExample) |
| DK (1) | DK149610C (enExample) |
| FI (1) | FI73224C (enExample) |
| FR (1) | FR2460291A1 (enExample) |
| GB (1) | GB2058079B (enExample) |
| HU (1) | HU180926B (enExample) |
| IL (1) | IL60406A (enExample) |
| IT (1) | IT1174678B (enExample) |
| NL (1) | NL192575C (enExample) |
| PL (1) | PL123822B1 (enExample) |
| SE (1) | SE447389B (enExample) |
| SU (1) | SU1085505A3 (enExample) |
| YU (1) | YU43220B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU184481B (en) * | 1981-10-02 | 1984-08-28 | Richter Gedeon Vegyeszet | Process for producing tripeptides for diminishing appetite |
| CA1256650A (en) * | 1983-03-25 | 1989-06-27 | Toshinari Tamura | Process of producing 2-azetidinone-4-substituted compounds, and medicaments containing the compounds |
| GB2146026A (en) * | 1983-09-07 | 1985-04-11 | Tanabe Seiyaku Co | Peptides and process for preparing the same |
| JPS60190795A (ja) * | 1984-03-09 | 1985-09-28 | Takeda Chem Ind Ltd | ペプタイド |
| US4608365A (en) * | 1984-03-30 | 1986-08-26 | University Of Southern California | Treatment of neurologic functions |
| US4719207A (en) * | 1984-06-25 | 1988-01-12 | Yamanouchi Pharmaceutical Co., Ltd. | CNS active substituted azetidinone compounds |
| IL75641A (en) * | 1984-07-10 | 1990-11-05 | Tanabe Seiyaku Co | 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it |
| IE58849B1 (en) * | 1984-12-18 | 1993-11-17 | Gruenenthal Chemie | Use of dipeptide derivatives for the manufacture of medicaments for the treatment of patients with amyotrophic lateral sclerosis |
| JPS6222797A (ja) * | 1985-07-19 | 1987-01-30 | Tanabe Seiyaku Co Ltd | 新規ペプタイド |
| IT1202426B (it) * | 1987-01-26 | 1989-02-09 | Poli Ind Chimica Spa | Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono |
| JPH06104079B2 (ja) * | 1988-07-14 | 1994-12-21 | 日東紡績株式会社 | 新規な酵素活性測定用基質 |
| FR2649110B1 (fr) * | 1989-06-29 | 1994-10-21 | Adir | Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| DE69118784T2 (de) * | 1990-08-17 | 1996-09-19 | Japan Tobacco Inc | Neue Peptidderivate und deren pharmazeutischer Gebrauch |
| HU206374B (en) * | 1990-09-03 | 1992-10-28 | Richter Gedeon Vegyeszet | Process for producing pentapeptide and its salts specifically inhibiting proliferation of epidermic cells, as well as pharmaceutical compositions comprising same as active ingredient |
| IT1244548B (it) * | 1991-02-06 | 1994-07-15 | Poli Ind Chimica Spa | Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche |
| US20020151502A1 (en) * | 1997-10-09 | 2002-10-17 | Albert Sattin | Tri-peptides for neurological and neurobehavior applications |
| US20050233973A1 (en) * | 1997-10-09 | 2005-10-20 | Albert Sattin | Tri-peptides for antidepressant applications |
| AU2001266347A1 (en) * | 2000-07-11 | 2002-01-21 | Shionogi And Co., Ltd. | Enteric preparations containing physiologically active peptides |
| TWI285110B (en) * | 2000-08-31 | 2007-08-11 | Shionogi & Co | Parkinson disease therapeutic agent |
| US8143369B2 (en) * | 2009-06-02 | 2012-03-27 | International Business Machines Corporation | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof |
| EP3485871B1 (en) * | 2016-07-14 | 2025-12-24 | Resonac Corporation | Non-therapeutic use of an orotic acid derivative for inhibiting melanin production and whitening the skin |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2343037A1 (de) * | 1973-08-25 | 1975-03-06 | Hoechst Ag | Arzneimittel mit antidepressiver wirkung |
| US3959248A (en) * | 1974-04-03 | 1976-05-25 | Merck & Co., Inc. | Analogs of thyrotropin-releasing hormone |
| SE408300B (sv) * | 1974-10-16 | 1979-06-05 | Gruenenthal Chemie | Sett att framstella nya dipeptidderivat |
| DE2449167C2 (de) * | 1974-10-16 | 1984-05-24 | Grünenthal GmbH, 5190 Stolberg | N-Acyl-L-histidyl-L-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
| JPS5944308B2 (ja) * | 1976-03-23 | 1984-10-29 | 武田薬品工業株式会社 | ペプタイド |
-
1979
- 1979-06-28 HU HU79RI718A patent/HU180926B/hu unknown
-
1980
- 1980-06-26 IT IT23097/80A patent/IT1174678B/it active
- 1980-06-26 SU SU802940703A patent/SU1085505A3/ru active
- 1980-06-26 AT AT0334780A patent/AT380259B/de not_active IP Right Cessation
- 1980-06-26 CS CS804583A patent/CS241028B2/cs unknown
- 1980-06-26 DK DK274580A patent/DK149610C/da not_active IP Right Cessation
- 1980-06-26 FR FR8014194A patent/FR2460291A1/fr active Granted
- 1980-06-26 JP JP8723680A patent/JPS568354A/ja active Granted
- 1980-06-26 SE SE8004745A patent/SE447389B/sv not_active IP Right Cessation
- 1980-06-26 BE BE1/9867A patent/BE884015A/fr not_active IP Right Cessation
- 1980-06-26 DD DD80222174A patent/DD151745A5/de not_active IP Right Cessation
- 1980-06-26 IL IL60406A patent/IL60406A/xx unknown
- 1980-06-27 US US06/163,830 patent/US4386073A/en not_active Expired - Lifetime
- 1980-06-27 NL NL8003766A patent/NL192575C/nl not_active IP Right Cessation
- 1980-06-27 GB GB8021110A patent/GB2058079B/en not_active Expired
- 1980-06-27 FI FI802058A patent/FI73224C/fi not_active IP Right Cessation
- 1980-06-27 CA CA000354997A patent/CA1188296A/en not_active Expired
- 1980-06-27 AU AU59720/80A patent/AU538621B2/en not_active Ceased
- 1980-06-27 PL PL1980225269A patent/PL123822B1/pl unknown
- 1980-06-27 CH CH4956/80A patent/CH650519A5/de not_active IP Right Cessation
- 1980-06-27 DE DE19803024256 patent/DE3024256A1/de active Granted
- 1980-06-27 YU YU1695/80A patent/YU43220B/xx unknown
-
1994
- 1994-01-10 BG BG098367A patent/BG60739B2/bg unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19990627 |