GB201811450D0 - Mesothelin and CD137 binding molecules - Google Patents

Mesothelin and CD137 binding molecules

Info

Publication number
GB201811450D0
GB201811450D0 GBGB1811450.4A GB201811450A GB201811450D0 GB 201811450 D0 GB201811450 D0 GB 201811450D0 GB 201811450 A GB201811450 A GB 201811450A GB 201811450 D0 GB201811450 D0 GB 201811450D0
Authority
GB
United Kingdom
Prior art keywords
mesothelin
binding molecules
molecules
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1811450.4A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Star Delta Ltd
Original Assignee
F Star Delta Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Star Delta Ltd filed Critical F Star Delta Ltd
Priority to GBGB1811450.4A priority Critical patent/GB201811450D0/en
Publication of GB201811450D0 publication Critical patent/GB201811450D0/en
Priority to FIEP19742323.9T priority patent/FI3820894T3/fi
Priority to IL280007A priority patent/IL280007B2/en
Priority to AU2019303081A priority patent/AU2019303081A1/en
Priority to PT197423239T priority patent/PT3820894T/pt
Priority to US17/259,634 priority patent/US12319739B2/en
Priority to TW108124775A priority patent/TWI839365B/zh
Priority to EP19742323.9A priority patent/EP3820894B1/en
Priority to CN201980046873.7A priority patent/CN112437776B/zh
Priority to PCT/EP2019/068817 priority patent/WO2020011976A1/en
Priority to BR112021000396-7A priority patent/BR112021000396A2/pt
Priority to DK19742323.9T priority patent/DK3820894T3/da
Priority to MX2021000397A priority patent/MX2021000397A/es
Priority to KR1020217000265A priority patent/KR20210030925A/ko
Priority to PL19742323.9T priority patent/PL3820894T3/pl
Priority to HRP20250872TT priority patent/HRP20250872T1/hr
Priority to CA3103173A priority patent/CA3103173A1/en
Priority to HUE19742323A priority patent/HUE072217T2/hu
Priority to ES19742323T priority patent/ES3035107T3/es
Priority to JP2021500386A priority patent/JP7360441B2/ja
Priority to SG11202011960XA priority patent/SG11202011960XA/en
Priority to ARP190101973A priority patent/AR115769A1/es
Priority to ZA2020/07570A priority patent/ZA202007570B/en
Priority to JP2023169048A priority patent/JP7803907B2/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/35—Valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/72—Increased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GBGB1811450.4A 2018-07-12 2018-07-12 Mesothelin and CD137 binding molecules Ceased GB201811450D0 (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
GBGB1811450.4A GB201811450D0 (en) 2018-07-12 2018-07-12 Mesothelin and CD137 binding molecules
ARP190101973A AR115769A1 (es) 2018-07-12 2019-07-12 Moléculas de unión a mesotelina y cd137
BR112021000396-7A BR112021000396A2 (pt) 2018-07-12 2019-07-12 Moléculas de ligação a mesotelina e cd137
MX2021000397A MX2021000397A (es) 2018-07-12 2019-07-12 Moleculas de union a mesotelina y cd137.
AU2019303081A AU2019303081A1 (en) 2018-07-12 2019-07-12 Mesothelin and CD137 binding molecules
PT197423239T PT3820894T (pt) 2018-07-12 2019-07-12 Moléculas de ligação a mesotelina e cd137
US17/259,634 US12319739B2 (en) 2018-07-12 2019-07-12 Mesothelin and CD137 binding molecules
TW108124775A TWI839365B (zh) 2018-07-12 2019-07-12 間皮素及cd137結合分子
EP19742323.9A EP3820894B1 (en) 2018-07-12 2019-07-12 Mesothelin and cd137 binding molecules
CN201980046873.7A CN112437776B (zh) 2018-07-12 2019-07-12 间皮素和cd137结合分子
PCT/EP2019/068817 WO2020011976A1 (en) 2018-07-12 2019-07-12 Mesothelin and cd137 binding molecules
FIEP19742323.9T FI3820894T3 (fi) 2018-07-12 2019-07-12 Mesoteliinia ja vastaavasti cd137:ää sitovia molekyylejä
DK19742323.9T DK3820894T3 (da) 2018-07-12 2019-07-12 Mesothelin- og cd137-bindende molekyler
IL280007A IL280007B2 (en) 2018-07-12 2019-07-12 Mesothelin and CD137 binding molecules
KR1020217000265A KR20210030925A (ko) 2018-07-12 2019-07-12 메소텔린 및 cd137 결합 분자
PL19742323.9T PL3820894T3 (pl) 2018-07-12 2019-07-12 Mezotelina i cząsteczki wiążące cd137
HRP20250872TT HRP20250872T1 (hr) 2018-07-12 2019-07-12 Molekule koje vežu mezotelin i cd137
CA3103173A CA3103173A1 (en) 2018-07-12 2019-07-12 Mesothelin and cd137 binding molecules
HUE19742323A HUE072217T2 (hu) 2018-07-12 2019-07-12 Mezotelin- és CD137-kötõ molekulák
ES19742323T ES3035107T3 (en) 2018-07-12 2019-07-12 Mesothelin and cd137 binding molecules
JP2021500386A JP7360441B2 (ja) 2018-07-12 2019-07-12 メソテリン及びｃｄ１３７結合分子
SG11202011960XA SG11202011960XA (en) 2018-07-12 2019-07-12 Mesothelin and cd137 binding molecules
ZA2020/07570A ZA202007570B (en) 2018-07-12 2020-12-04 Mesothelin and cd137 binding molecules
JP2023169048A JP7803907B2 (ja) 2018-07-12 2023-09-29 メソテリン及びｃｄ１３７結合分子

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1811450.4A GB201811450D0 (en) 2018-07-12 2018-07-12 Mesothelin and CD137 binding molecules

Publications (1)

Publication Number Publication Date
GB201811450D0 true GB201811450D0 (en) 2018-08-29

Family

ID=63273224

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1811450.4A Ceased GB201811450D0 (en) 2018-07-12 2018-07-12 Mesothelin and CD137 binding molecules

Country Status (23)

Country Link
US (1) US12319739B2 (https=)
EP (1) EP3820894B1 (https=)
JP (2) JP7360441B2 (https=)
KR (1) KR20210030925A (https=)
CN (1) CN112437776B (https=)
AR (1) AR115769A1 (https=)
AU (1) AU2019303081A1 (https=)
BR (1) BR112021000396A2 (https=)
CA (1) CA3103173A1 (https=)
DK (1) DK3820894T3 (https=)
ES (1) ES3035107T3 (https=)
FI (1) FI3820894T3 (https=)
GB (1) GB201811450D0 (https=)
HR (1) HRP20250872T1 (https=)
HU (1) HUE072217T2 (https=)
IL (1) IL280007B2 (https=)
MX (1) MX2021000397A (https=)
PL (1) PL3820894T3 (https=)
PT (1) PT3820894T (https=)
SG (1) SG11202011960XA (https=)
TW (1) TWI839365B (https=)
WO (1) WO2020011976A1 (https=)
ZA (1) ZA202007570B (https=)

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GB201811450D0 (en) * 2018-07-12 2018-08-29 F Star Delta Ltd Mesothelin and CD137 binding molecules
PT3820569T (pt) 2018-07-12 2025-01-14 Invox Pharma Ltd Moléculas de anticorpo que se ligam a pd-l1 e cd137
ES3044118T3 (en) 2018-07-12 2025-11-26 Invox Pharma Ltd Antibody molecules that bind cd137 and ox40
GB201811408D0 (en) 2018-07-12 2018-08-29 F Star Beta Ltd CD137 Binding Molecules
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GB201811403D0 (en) 2018-07-12 2018-08-29 F Star Beta Ltd Antibody molecules
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