GB0112834D0 - Medicaments - Google Patents

Medicaments

Info

Publication number
GB0112834D0
GB0112834D0 GBGB0112834.7A GB0112834A GB0112834D0 GB 0112834 D0 GB0112834 D0 GB 0112834D0 GB 0112834 A GB0112834 A GB 0112834A GB 0112834 D0 GB0112834 D0 GB 0112834D0
Authority
GB
United Kingdom
Prior art keywords
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0112834.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Priority to GBGB0112834.7A priority Critical patent/GB0112834D0/en
Publication of GB0112834D0 publication Critical patent/GB0112834D0/en
Priority to ARP020101914A priority patent/AR038172A1/es
Priority to TW091110839A priority patent/TWI232219B/zh
Priority to AT02807202T priority patent/ATE380812T1/de
Priority to US10/478,154 priority patent/US7141564B2/en
Priority to PL02367079A priority patent/PL367079A1/xx
Priority to KR10-2003-7015379A priority patent/KR20040010654A/ko
Priority to EP02807202A priority patent/EP1399443B1/en
Priority to CA002448525A priority patent/CA2448525A1/en
Priority to BR0210016-9A priority patent/BR0210016A/pt
Priority to MXPA03010790A priority patent/MXPA03010790A/es
Priority to DE60224039T priority patent/DE60224039T2/de
Priority to HU0400017A priority patent/HUP0400017A2/hu
Priority to PCT/EP2002/005708 priority patent/WO2003087098A1/en
Priority to JP2003584054A priority patent/JP4463565B2/ja
Priority to IL15886902A priority patent/IL158869A0/xx
Priority to CNA028146689A priority patent/CN1535272A/zh
Priority to CZ20033202A priority patent/CZ20033202A3/cs
Priority to ES02807202T priority patent/ES2298439T3/es
Priority to AU2002367697A priority patent/AU2002367697A1/en
Priority to ZA200308696A priority patent/ZA200308696B/en
Priority to CO03101671A priority patent/CO5540344A2/es
Priority to NO20035190A priority patent/NO20035190D0/no
Priority to US11/604,045 priority patent/US20070135422A1/en
Priority to JP2009259981A priority patent/JP2010031057A/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GBGB0112834.7A 2001-05-25 2001-05-25 Medicaments Ceased GB0112834D0 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
GBGB0112834.7A GB0112834D0 (en) 2001-05-25 2001-05-25 Medicaments
ARP020101914A AR038172A1 (es) 2001-05-25 2002-05-23 Compuesto de ciclohexano y ciclohexeno, su uso para preparar una composicion farmaceutica, dicha composicion farmaceutica, procedimiento para preparar el compuesto y compuestos intermediarios en dicho procedimiento
TW091110839A TWI232219B (en) 2001-05-25 2002-05-23 Compounds containing cyclohexane group, process for preparing them and pharmaceutical composition containing them
AU2002367697A AU2002367697A1 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
HU0400017A HUP0400017A2 (hu) 2001-05-25 2002-05-24 Antibakteriális hatóanyakokként alkalmazható nitrogéntartalmú biciklusos heterociklusos vegyületek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
JP2003584054A JP4463565B2 (ja) 2001-05-25 2002-05-24 抗菌剤として用いるための窒素含有二環式複素環
PL02367079A PL367079A1 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
KR10-2003-7015379A KR20040010654A (ko) 2001-05-25 2002-05-24 항균제용 질소-함유 비시클릭 헤테로고리 화합물
EP02807202A EP1399443B1 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
CA002448525A CA2448525A1 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
BR0210016-9A BR0210016A (pt) 2001-05-25 2002-05-24 Heterociclos bicìclicos contendo nitrogênio, para uso como antibacterianos
MXPA03010790A MXPA03010790A (es) 2001-05-25 2002-05-24 Heterociclos biciclicos que contienen nitrogeno para uso como antibacterianos.
DE60224039T DE60224039T2 (de) 2001-05-25 2002-05-24 Stickstoffhaltige, bicyclische heterocyclen zur verwendung als antibakterielle mittel
AT02807202T ATE380812T1 (de) 2001-05-25 2002-05-24 Stickstoffhaltige, bicyclische heterocyclen zur verwendung als antibakterielle mittel
PCT/EP2002/005708 WO2003087098A1 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
US10/478,154 US7141564B2 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
IL15886902A IL158869A0 (en) 2001-05-25 2002-05-24 Nitrogen-containing bicyclic heterocycles for use as antibacterials
CNA028146689A CN1535272A (zh) 2001-05-25 2002-05-24 用于抗菌剂的二环含氮杂环
CZ20033202A CZ20033202A3 (cs) 2001-05-25 2002-05-24 Bicyklické heterocyklické sloučeniny obsahující dusík pro použití jako antibakteriální činidla
ES02807202T ES2298439T3 (es) 2001-05-25 2002-05-24 Heterociclos biciclicos que contienen nitrogeno para uso como agentes antibacterianos.
ZA200308696A ZA200308696B (en) 2001-05-25 2003-11-07 Nitrogen-containing bicyclic heterocycles for use as antibacterials.
CO03101671A CO5540344A2 (es) 2001-05-25 2003-11-18 Medicamentos
NO20035190A NO20035190D0 (no) 2001-05-25 2003-11-21 Nitrogenholdige bisykliske heterosykler for anvendelse som antibakteriellemidler
US11/604,045 US20070135422A1 (en) 2001-05-25 2006-11-22 Nitrogen-containing bicycle heterocycles for use as antibacterials
JP2009259981A JP2010031057A (ja) 2001-05-25 2009-11-13 抗菌剤として用いるための窒素含有二環式複素環

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0112834.7A GB0112834D0 (en) 2001-05-25 2001-05-25 Medicaments

Publications (1)

Publication Number Publication Date
GB0112834D0 true GB0112834D0 (en) 2001-07-18

Family

ID=9915342

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0112834.7A Ceased GB0112834D0 (en) 2001-05-25 2001-05-25 Medicaments

Country Status (23)

Country Link
US (2) US7141564B2 (https=)
EP (1) EP1399443B1 (https=)
JP (2) JP4463565B2 (https=)
KR (1) KR20040010654A (https=)
CN (1) CN1535272A (https=)
AR (1) AR038172A1 (https=)
AT (1) ATE380812T1 (https=)
AU (1) AU2002367697A1 (https=)
BR (1) BR0210016A (https=)
CA (1) CA2448525A1 (https=)
CO (1) CO5540344A2 (https=)
CZ (1) CZ20033202A3 (https=)
DE (1) DE60224039T2 (https=)
ES (1) ES2298439T3 (https=)
GB (1) GB0112834D0 (https=)
HU (1) HUP0400017A2 (https=)
IL (1) IL158869A0 (https=)
MX (1) MXPA03010790A (https=)
NO (1) NO20035190D0 (https=)
PL (1) PL367079A1 (https=)
TW (1) TWI232219B (https=)
WO (1) WO2003087098A1 (https=)
ZA (1) ZA200308696B (https=)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9703377D0 (sv) * 1997-09-18 1997-09-18 Astra Ab New compounds
US6803369B1 (en) 2000-07-25 2004-10-12 Smithkline Beecham Corporation Compounds and methods for the treatment of neoplastic disease
EP1305308B1 (en) 2000-07-26 2006-12-20 Smithkline Beecham Plc Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
WO2002024684A1 (en) * 2000-09-21 2002-03-28 Smithkline Beecham P.L.C. Quinoline derivatives as antibacterials
GB0031088D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
EP1470131A2 (en) 2002-01-29 2004-10-27 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
US7312212B2 (en) 2002-01-29 2007-12-25 Glaxo Group Limited Aminopiperidine derivatives
TW200406413A (en) * 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
EP1560488B1 (en) 2002-11-05 2010-09-01 Glaxo Group Limited Antibacterial agents
US7232832B2 (en) * 2002-11-05 2007-06-19 Smithkline Beecham Corporation Antibacterial agents
WO2004050036A2 (en) 2002-12-04 2004-06-17 Glaxo Group Limited Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents
WO2004054581A2 (en) * 2002-12-13 2004-07-01 Smithkline Beecham Corporation Cyclohexyl compounds as ccr5 antagonists
AR042486A1 (es) * 2002-12-18 2005-06-22 Glaxo Group Ltd Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion .
DE102004023635A1 (de) * 2004-05-10 2006-04-13 Grünenthal GmbH Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate
DE102004041163A1 (de) * 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
WO2006081182A2 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
EP1845995A4 (en) 2005-01-25 2010-03-03 Glaxo Group Ltd ANTIBACTERIAL AGENTS
US7511035B2 (en) 2005-01-25 2009-03-31 Glaxo Group Limited Antibacterial agents
JP2008528586A (ja) * 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
JP2008528598A (ja) * 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
ATE536351T1 (de) 2006-01-26 2011-12-15 Actelion Pharmaceuticals Ltd Tetrahydropyran-antibiotika
ES2353829T3 (es) * 2006-02-15 2011-03-07 Actelion Pharmaceuticals Ltd. Derivados antibioticos de etanol o de 1,2-etanodiolciclohexilo.
WO2007098214A1 (en) * 2006-02-21 2007-08-30 Amgen Inc. Cinnoline derivatives as phosphodiesterase 10 inhibitors
US20070287707A1 (en) * 2006-02-28 2007-12-13 Arrington Mark P Phosphodiesterase 10 inhibitors
WO2007103554A1 (en) * 2006-03-08 2007-09-13 Amgen Inc. Quinoline and isoquinoline derivatives as phosphodiesterase 10 inhibitors
EP2001887B1 (en) 2006-04-06 2010-09-15 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
WO2007118130A2 (en) 2006-04-06 2007-10-18 Glaxo Group Limited Antibacterial agents
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
TW200819457A (en) 2006-08-30 2008-05-01 Actelion Pharmaceuticals Ltd Spiro antibiotic derivatives
CL2007003693A1 (es) * 2006-12-22 2008-06-27 Actelion Pharmaceuticals Ltd Compuestos derivados de pirido [3,2-b] [1,4] tiazina; composicion farmaceutica que contiene dichos compuestos; y su uso en el tratamiento de infecciones bacterianas.
CL2008001003A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
AU2008240764C1 (en) * 2007-04-20 2011-10-20 Glaxo Group Limited Tricyclic nitrogen containing compounds as antibacterial agents
PL2245028T3 (pl) 2007-12-18 2012-07-31 Actelion Pharmaceuticals Ltd Pochodne 5-aminocyklilometyloksazolidyn-2-onu
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
KR101592046B1 (ko) 2008-02-22 2016-02-05 액테리온 파마슈티칼 리미티드 옥사졸리디논 유도체
TW200944529A (en) 2008-04-15 2009-11-01 Actelion Pharmaceuticals Ltd Tricyclic antibiotics
US7741327B2 (en) 2008-04-16 2010-06-22 Hoffmann-La Roche Inc. Pyrrolidinone glucokinase activators
MX2010012855A (es) * 2008-06-03 2010-12-21 Actelion Pharmaceuticals Ltd Derivados de [4-(1-amino-etil)-ciclohexil]-metil-amina y [6-(1-amino-etil)-tetrahidro-piran-3-il]-metil-amina como antibacterianos.
EP2352734A1 (en) 2008-10-17 2011-08-10 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
WO2010045987A1 (en) * 2008-10-23 2010-04-29 Glaxo Group Limited Substituted (aza) -1-methyl-1h-quin0lin-2-0nes as antibacterials
BRPI0921038A2 (pt) 2008-11-17 2019-09-24 Hoffmann La Roche ácido naftilacéticos
AU2009325902B2 (en) 2008-12-12 2015-01-29 Idorsia Pharmaceuticals Ltd 5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives
US8318940B2 (en) 2009-01-15 2012-11-27 Glaxo Group Limited Naphthyridin-2 (1 H)-one compounds useful as antibacterials
AR076222A1 (es) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
US8394858B2 (en) 2009-12-03 2013-03-12 Novartis Ag Cyclohexane derivatives and uses thereof
US8178689B2 (en) 2010-06-17 2012-05-15 Hoffman-La Roche Inc. Tricyclic compounds
KR20140048891A (ko) * 2011-05-27 2014-04-24 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 치환된 2-벤질리덴-2H-벤조[b][1,4]티아진-3(4H)-온, 이의 유도체, 및 이의 치료적 용도
US8470884B2 (en) 2011-11-09 2013-06-25 Hoffmann-La Roche Inc. Alkenyl naphthylacetic acids
AR089929A1 (es) 2012-02-10 2014-10-01 Actelion Pharmaceuticals Ltd Proceso para manufacturar un derivado de naftiridina
HK1220977A1 (en) * 2013-03-29 2017-05-19 Daiichi Sankyo Co., Ltd Method for producing (1s,4s,5s)-4-bromo-6-oxabicyclo[3.2.1]octan-7-one
LT2998296T (lt) 2013-05-13 2018-08-10 Shanghai Hengrui Pharmaceutical Co. Ltd. Cikloalkilo rūgšties darinys, jo gavimo būdas ir jo farmacinis taikymas
US10702521B2 (en) 2014-08-22 2020-07-07 Glaxosmithkline Intellectual Property Development Limited Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones
DK3209655T3 (da) 2014-10-24 2020-09-28 Landos Biopharma Inc Lanthioninsyntease C-lignende 2-baserede Therapeutica
TW201722965A (zh) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物
WO2018172250A1 (en) 2017-03-21 2018-09-27 Bayer Pharma Aktiengesellschaft 2-methyl-quinazolines
KR20200090873A (ko) 2017-11-30 2020-07-29 란도스 바이오파마, 인크. 란티오닌 c-유사 단백질 2 리간드 및 이와 함께 제조된 세포를 이용한 치료법
US20220274979A1 (en) 2018-04-18 2022-09-01 Bayer Pharma Aktiengesellschaft 2-methyl-aza-quinazolines
KR20220087497A (ko) 2019-10-18 2022-06-24 더 리전츠 오브 더 유니버시티 오브 캘리포니아 병원성 혈관을 표적화하기 위한 화합물 및 방법
US12590298B2 (en) 2019-10-18 2026-03-31 The Regents Of The University Of California Ex vivo tumor angiogenesis model
KR20230026522A (ko) 2019-12-20 2023-02-24 란도스 바이오파마, 인크. 란티오닌 c-유사 단백질 2 리간드, 이로 제조된 세포, 및 이를 사용하는 치료법
US20230357239A1 (en) 2020-09-18 2023-11-09 Bayer Aktiengesellschaft Pyrido[2,3-d]pyrimidin-4-amines as sos1 inhibitors
EP4074317A1 (en) 2021-04-14 2022-10-19 Bayer AG Phosphorus derivatives as novel sos1 inhibitors
CN116102537B (zh) * 2021-11-10 2024-10-01 四川大学 一种喹啉酮类衍生物及其制备方法和用途
CN117568087B (zh) * 2024-01-16 2024-04-05 洛阳轻捷润滑油科技有限公司 一种长寿命汽车无极变速器油及其制备方法

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472404A (en) * 1982-08-16 1984-09-18 The Dow Chemical Company 8-Quinolinyl carbamates and their use as urinary tract antimicrobials
US4925877A (en) 1986-02-25 1990-05-15 Zaidanhojin Biseibutsu Kagaku Kenkyukai Physiologically active erbstatin analogue compounds and compositions
US4971996A (en) 1987-03-11 1990-11-20 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Hydroxystyrene compounds which are useful as tyrosine kinase inhibitors
ZA899436B (en) 1988-12-12 1990-08-29 Ciba Geigy Piperidine derivatives
EP0541486A1 (de) 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclische Konjugate
US5263276A (en) 1992-09-21 1993-11-23 Fred Washington Fishing rod attachment
PT672041E (pt) 1993-10-01 2002-04-29 Novartis Ag Derivados da piridina farmacologicamente activos e processos para a sua preparacao
JPH07179407A (ja) 1993-11-12 1995-07-18 Green Cross Corp:The 新規縮合環系化合物またはその塩、およびその医薬用途
PT765313E (pt) 1994-06-17 2003-11-28 Hoffmann La Roche Derivados de n,n'-bis(quinolin-4-il)-diamina a sua preparacao e a sua utilizacao como agentes anti-malaria
PL181893B1 (pl) 1994-11-14 2001-10-31 Warner Lambert Co Zwiazki bedace pochodnymi pirymidyny i naftyrydyny oraz preparat farmaceutyczny zawierajacy je PL PL PL
US5589482A (en) 1994-12-14 1996-12-31 Pfizer Inc. Benzo-thiophene estrogen agonists to treat prostatic hyperplasia
WO1996023782A1 (en) * 1995-02-02 1996-08-08 Daiichi Pharmaceutical Co., Ltd. Heterocyclic compounds
ES2149468T3 (es) 1995-04-26 2000-11-01 Kyowa Hakko Kogyo Kk Derivados de radicicol.
GB9514265D0 (en) 1995-07-13 1995-09-13 Wellcome Found Hetrocyclic compounds
DE69614149T2 (de) 1995-11-16 2002-03-14 F. Hoffmann-La Roche Ag, Basel Chinolinderivate als antimalariamittel
US5707990A (en) 1996-01-30 1998-01-13 Ortho Pharmaceutical Corporation 2-substituted amino and thio alkyl benzoxazine antimicrobial agents
EP0960104B1 (en) 1996-04-17 2004-06-16 Bristol-Myers Squibb Pharma Company N-(amidinophenyl)-n'-(subst.)-3h-2,4-benzodiazepin-3-one derivatives as factor xa inhibitors
HRP970371A2 (en) 1996-07-13 1998-08-31 Kathryn Jane Smith Heterocyclic compounds
AR007857A1 (es) 1996-07-13 1999-11-24 Glaxo Group Ltd Compuestos heterociclicos fusionados como inhibidores de proteina tirosina quinasa, sus metodos de preparacion, intermediarios uso en medicina ycomposiciones farmaceuticas que los contienen.
EP0946164A4 (en) 1996-10-30 2000-08-23 Merck & Co Inc INTEGRIN ANTAGONISTS
TW523506B (en) 1996-12-18 2003-03-11 Ono Pharmaceutical Co Sulfonamide or carbamide derivatives and drugs containing the same as active ingredients
AU730224B2 (en) 1996-12-23 2001-03-01 Du Pont Pharmaceuticals Company Nitrogen containing heteroaromatics as factor Xa inhibitors
US6187797B1 (en) * 1996-12-23 2001-02-13 Dupont Pharmaceuticals Company Phenyl-isoxazoles as factor XA Inhibitors
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
CA2318842A1 (en) 1998-01-26 1999-07-29 Julie Dorothy Warrack Quinoline derivatives as antibacterials
NZ507760A (en) 1998-03-26 2002-10-25 Japan Tobacco Inc Amide derivatives and nociceptin antagonists
SE9802206D0 (sv) 1998-06-22 1998-06-22 Astra Pharma Inc Novel compounds
GB9822440D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
CN1136217C (zh) 1998-12-17 2004-01-28 霍夫曼-拉罗奇有限公司 作为jnk蛋白质激酶抑制剂的4-芳基羟吲哚
JP2002535323A (ja) 1999-01-20 2002-10-22 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー プロテインキナーゼ阻害剤としてのピペリジニルキノリン
EP1150565A1 (en) 1999-02-08 2001-11-07 LION bioscience AG Thiazole derivatives and combinatorial libraries thereof
GB9910579D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
GB9910577D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
GB9910580D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
GB9914074D0 (en) * 1999-06-16 1999-08-18 Btg Int Ltd Tibial component
GB9914486D0 (en) 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
AU5567000A (en) 1999-06-24 2001-01-09 Toray Industries, Inc. Alpha1b-adrenergic receptor antagonists
GB9917406D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917408D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
FR2798656B1 (fr) 1999-09-17 2004-12-17 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent
ES2316383T3 (es) 1999-09-17 2009-04-16 Millennium Pharmaceuticals, Inc. Benzamidas e inhibidores relacionados del factor xa.
DE19955476A1 (de) 1999-11-18 2001-05-23 Boehringer Ingelheim Pharma Bis-basische Verbindungen als Tryptase-Inhibitoren, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
IL151552A0 (en) 2000-03-17 2003-04-10 Bristol Myers Squibb Pharma Co Cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha
WO2001070737A2 (en) 2000-03-20 2001-09-27 Sepracor, Inc. Therapeutic heterocyclic compounds for the treatment of asthma and allergy and use thereof
EP1272483A2 (en) 2000-03-24 2003-01-08 Millenium Pharmaceuticals, Inc. OXINDOLE INHIBITORS OF FACTOR Xa
WO2001072712A1 (en) 2000-03-24 2001-10-04 Cor Therapeutics, Inc. ISOQUINOLONE INHIBITORS OF FACTOR Xa
TWI290136B (en) 2000-04-05 2007-11-21 Daiichi Seiyaku Co Ethylenediamine derivatives
EP1305308B1 (en) * 2000-07-26 2006-12-20 Smithkline Beecham Plc Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
WO2002024684A1 (en) 2000-09-21 2002-03-28 Smithkline Beecham P.L.C. Quinoline derivatives as antibacterials
FR2816618B1 (fr) 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
GB0031086D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0031088D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
FR2822154B1 (fr) 2001-03-13 2005-10-21 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
EP1470131A2 (en) * 2002-01-29 2004-10-27 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
US7312212B2 (en) * 2002-01-29 2007-12-25 Glaxo Group Limited Aminopiperidine derivatives
US6818772B2 (en) * 2002-02-22 2004-11-16 Abbott Laboratories Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
TW200406413A (en) * 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
FR2844270B1 (fr) 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
FR2844268B1 (fr) 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
EP1551829B1 (de) 2002-10-10 2010-04-07 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Neue verbindungen mit antibakterieller aktivität
AR042486A1 (es) * 2002-12-18 2005-06-22 Glaxo Group Ltd Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion .
DE10316081A1 (de) 2003-04-08 2004-10-21 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität

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NO20035190D0 (no) 2003-11-21
US20040171620A1 (en) 2004-09-02
WO2003087098A1 (en) 2003-10-23
TWI232219B (en) 2005-05-11
JP4463565B2 (ja) 2010-05-19
BR0210016A (pt) 2004-06-15
JP2010031057A (ja) 2010-02-12
ES2298439T3 (es) 2008-05-16
KR20040010654A (ko) 2004-01-31
MXPA03010790A (es) 2004-03-02
US20070135422A1 (en) 2007-06-14
ATE380812T1 (de) 2007-12-15
US7141564B2 (en) 2006-11-28
HUP0400017A2 (hu) 2004-06-28
CA2448525A1 (en) 2003-10-23
AU2002367697A1 (en) 2003-10-27
JP2005519981A (ja) 2005-07-07
DE60224039D1 (de) 2008-01-24
EP1399443A1 (en) 2004-03-24
EP1399443B1 (en) 2007-12-12
DE60224039T2 (de) 2008-11-27
IL158869A0 (en) 2004-05-12
CO5540344A2 (es) 2005-07-29
CN1535272A (zh) 2004-10-06
ZA200308696B (en) 2004-05-21

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