GB0029895D0 - Organic compounds - Google Patents

Organic compounds

Info

Publication number
GB0029895D0
GB0029895D0 GBGB0029895.0A GB0029895A GB0029895D0 GB 0029895 D0 GB0029895 D0 GB 0029895D0 GB 0029895 A GB0029895 A GB 0029895A GB 0029895 D0 GB0029895 D0 GB 0029895D0
Authority
GB
United Kingdom
Prior art keywords
organic compounds
compounds
organic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0029895.0A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Priority to GBGB0029895.0A priority Critical patent/GB0029895D0/en
Publication of GB0029895D0 publication Critical patent/GB0029895D0/en
Priority to PE2001001192A priority patent/PE20020568A1/es
Priority to TW090129838A priority patent/TWI286137B/zh
Priority to US10/433,808 priority patent/US6946561B2/en
Priority to CNB018201415A priority patent/CN1263761C/zh
Priority to AT01994791T priority patent/ATE292132T1/de
Priority to CA2433414A priority patent/CA2433414C/en
Priority to PT01994791T priority patent/PT1345944E/pt
Priority to HU0302579A priority patent/HU224910B1/hu
Priority to JP2002547933A priority patent/JP4287650B2/ja
Priority to DK01994791T priority patent/DK1345944T3/da
Priority to PL361884A priority patent/PL209406B1/pl
Priority to ARP010105667A priority patent/AR031902A1/es
Priority to RU2003119659/04A priority patent/RU2285007C2/ru
Priority to MXPA03005097A priority patent/MXPA03005097A/es
Priority to NZ526197A priority patent/NZ526197A/en
Priority to SI200130358T priority patent/SI1345944T1/sl
Priority to EP01994791A priority patent/EP1345944B1/en
Priority to DE60109814T priority patent/DE60109814T2/de
Priority to AU2493602A priority patent/AU2493602A/xx
Priority to IL15608801A priority patent/IL156088A0/xx
Priority to PCT/EP2001/014771 priority patent/WO2002046196A1/en
Priority to CZ20031565A priority patent/CZ301664B6/cs
Priority to ES01994791T priority patent/ES2239687T3/es
Priority to BR0115991-7A priority patent/BR0115991A/pt
Priority to SK689-2003A priority patent/SK287356B6/sk
Priority to MYPI20015563A priority patent/MY128409A/en
Priority to KR1020037007114A priority patent/KR100894990B1/ko
Priority to AU2002224936A priority patent/AU2002224936B2/en
Priority to IL156088A priority patent/IL156088A/en
Priority to ZA200304296A priority patent/ZA200304296B/en
Priority to EC2003004641A priority patent/ECSP034641A/es
Priority to NO20032591A priority patent/NO329164B1/no
Priority to HK04100923A priority patent/HK1059618A1/xx
Priority to US11/205,892 priority patent/US7569698B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Silicon Polymers (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GBGB0029895.0A 2000-12-07 2000-12-07 Organic compounds Ceased GB0029895D0 (en)

Priority Applications (35)

Application Number Priority Date Filing Date Title
GBGB0029895.0A GB0029895D0 (en) 2000-12-07 2000-12-07 Organic compounds
PE2001001192A PE20020568A1 (es) 2000-12-07 2001-11-28 Proceso para el aislamiento y la purificacion de epotilonas
TW090129838A TWI286137B (en) 2000-12-07 2001-12-03 Process for the isolation and purification of epothilones
AU2002224936A AU2002224936B2 (en) 2000-12-07 2001-12-05 Process for the isolation and purification of epothilones
SI200130358T SI1345944T1 (sl) 2000-12-07 2001-12-05 Postopek izolacije in ciscenje epotilonov
IL15608801A IL156088A0 (en) 2000-12-07 2001-12-05 Process for the isolation and purification of epothilones
AT01994791T ATE292132T1 (de) 2000-12-07 2001-12-05 Prozess zur isolierung und reinigung von epothilonen
CA2433414A CA2433414C (en) 2000-12-07 2001-12-05 Process for the isolation and purification of epothilones
PT01994791T PT1345944E (pt) 2000-12-07 2001-12-05 Processo para o isolamento e purificacao de epotilonas
HU0302579A HU224910B1 (en) 2000-12-07 2001-12-05 Process for the isolation and purification of epothilones
JP2002547933A JP4287650B2 (ja) 2000-12-07 2001-12-05 エポチロン類を単離および精製する方法
DK01994791T DK1345944T3 (da) 2000-12-07 2001-12-05 Fremgangsmåde til isolering og oprensning af epothiloner
PL361884A PL209406B1 (pl) 2000-12-07 2001-12-05 Sposób obróbki epotylonów A i/lub B i/lub E i/lub F z mieszaniny reakcyjnej, sposób desorpcji i sposób wyodrębniania epotylonów A i/lub B i/lub E i/lub F z żywicy syntetycznej oraz zastosowanie rozpuszczalnika do desorpcji tych epotylonów
ARP010105667A AR031902A1 (es) 2000-12-07 2001-12-05 Proceso para el aislamiento y la purificacion de epotilonas
RU2003119659/04A RU2285007C2 (ru) 2000-12-07 2001-12-05 Способ выделения эпотилонов из реакционной смеси и десорбции из синтетической смолы (варианты), применение слабополярного или аполярного растворителя для осуществления способов
MXPA03005097A MXPA03005097A (es) 2000-12-07 2001-12-05 Proceso para el aislamiento y purificacion de epotilonas.
NZ526197A NZ526197A (en) 2000-12-07 2001-12-05 Process for the isolation and purification of epothilones
US10/433,808 US6946561B2 (en) 2000-12-07 2001-12-05 Process for the isolation and purification of epothilones
EP01994791A EP1345944B1 (en) 2000-12-07 2001-12-05 Process for the isolation and purification of epothilones
DE60109814T DE60109814T2 (de) 2000-12-07 2001-12-05 Prozess zur isolierung und reinigung von epothilonen
AU2493602A AU2493602A (en) 2000-12-07 2001-12-05 Process for the isolation and purification of epothilones
CNB018201415A CN1263761C (zh) 2000-12-07 2001-12-05 分离和提纯埃坡霉素的方法
PCT/EP2001/014771 WO2002046196A1 (en) 2000-12-07 2001-12-05 Process for the isolation and purification of epothilones
CZ20031565A CZ301664B6 (cs) 2000-12-07 2001-12-05 Zpusob desorpce a získání epothilonu A, B, D, E a/nebo F a použití slabe polárního nebo nepolárního rozpouštedla pro desorpci epothilonu A, B, D, E a/nebo F z pryskyrice
ES01994791T ES2239687T3 (es) 2000-12-07 2001-12-05 Procedimiento para el aislamiento y la purificacion de epotilonas.
BR0115991-7A BR0115991A (pt) 2000-12-07 2001-12-05 Processo para o isolamento e a purificação de epotilonas
SK689-2003A SK287356B6 (sk) 2000-12-07 2001-12-05 Spôsob desorpcie epothilónov
MYPI20015563A MY128409A (en) 2000-12-07 2001-12-05 Process for the isolation and purification of epothilones
KR1020037007114A KR100894990B1 (ko) 2000-12-07 2001-12-05 에포틸론의 분리 및 정제 방법
IL156088A IL156088A (en) 2000-12-07 2003-05-22 Process for isolation and purification of apothilones
ZA200304296A ZA200304296B (en) 2000-12-07 2003-06-02 Process for the isolation and purification of epothilones.
EC2003004641A ECSP034641A (es) 2000-12-07 2003-06-03 Proceso para el aislamiento y purificacion de epotilonas
NO20032591A NO329164B1 (no) 2000-12-07 2003-06-06 Fremgangsmate for a desorbere, isolere og opparbeide epotiloner og anvendelse av svakt polare eller apolare losemidler for desorpsjon av epotiloner
HK04100923A HK1059618A1 (en) 2000-12-07 2004-02-11 Process for the isolation and purification of epothilones.
US11/205,892 US7569698B2 (en) 2000-12-07 2005-08-17 Process for the isolation and purification of epothilones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0029895.0A GB0029895D0 (en) 2000-12-07 2000-12-07 Organic compounds

Publications (1)

Publication Number Publication Date
GB0029895D0 true GB0029895D0 (en) 2001-01-24

Family

ID=9904660

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0029895.0A Ceased GB0029895D0 (en) 2000-12-07 2000-12-07 Organic compounds

Country Status (32)

Country Link
US (2) US6946561B2 (pl)
EP (1) EP1345944B1 (pl)
JP (1) JP4287650B2 (pl)
KR (1) KR100894990B1 (pl)
CN (1) CN1263761C (pl)
AR (1) AR031902A1 (pl)
AT (1) ATE292132T1 (pl)
AU (2) AU2493602A (pl)
BR (1) BR0115991A (pl)
CA (1) CA2433414C (pl)
CZ (1) CZ301664B6 (pl)
DE (1) DE60109814T2 (pl)
DK (1) DK1345944T3 (pl)
EC (1) ECSP034641A (pl)
ES (1) ES2239687T3 (pl)
GB (1) GB0029895D0 (pl)
HK (1) HK1059618A1 (pl)
HU (1) HU224910B1 (pl)
IL (2) IL156088A0 (pl)
MX (1) MXPA03005097A (pl)
MY (1) MY128409A (pl)
NO (1) NO329164B1 (pl)
NZ (1) NZ526197A (pl)
PE (1) PE20020568A1 (pl)
PL (1) PL209406B1 (pl)
PT (1) PT1345944E (pl)
RU (1) RU2285007C2 (pl)
SI (1) SI1345944T1 (pl)
SK (1) SK287356B6 (pl)
TW (1) TWI286137B (pl)
WO (1) WO2002046196A1 (pl)
ZA (1) ZA200304296B (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2273083C (en) * 1996-12-03 2012-09-18 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US6867305B2 (en) 1996-12-03 2005-03-15 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
US6194181B1 (en) * 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
US20020058286A1 (en) * 1999-02-24 2002-05-16 Danishefsky Samuel J. Synthesis of epothilones, intermediates thereto and analogues thereof
GB0029895D0 (en) * 2000-12-07 2001-01-24 Novartis Ag Organic compounds
US7649006B2 (en) * 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
ATE350383T1 (de) * 2002-08-23 2007-01-15 Sloan Kettering Inst Cancer Synthese von epothilonen, zwischenprodukte dafür, analoga und deren verwendungen
EP1542998A4 (en) 2002-09-23 2007-01-31 Bristol Myers Squibb Co PROCESS FOR THE PREPARATION, ISOLATION AND PURIFICATION OF EPOTHILON B, AND RINSE CRYSTAL STRUCTURES OF EPOTHILON B
FR2846520B1 (fr) 2002-11-06 2006-09-29 Roquette Freres Utilisation de maltodextrines branchees comme liants de granulation
KR100681811B1 (ko) * 2005-03-15 2007-02-12 성균관대학교산학협력단 생물학적 대사부산물의 효율적인 제거를 통한 유용 이차대사산물의 제조방법
CL2007002362A1 (es) 2006-08-16 2008-08-08 Novartis Ag Forma de cristal de la epotilona b; composicion farmaceutica que la comprende; y uso para el tratamiento de una enfermedad proliferativa, tal como un tumor.
EP2241566B1 (en) 2008-02-01 2013-08-21 Zhejiang Hisun Pharmaceutical Co. Ltd. A method for the separation and purification of epothilones
EP3566719A1 (en) 2010-05-18 2019-11-13 Cerulean Pharma Inc. Compositions and methods for treatment of autoimmune and other diseases
KR101372563B1 (ko) * 2011-12-26 2014-03-14 주식회사 삼양바이오팜 에포틸론 함유물질로부터 에포틸론 ａ와 ｂ의 추출 및 정제 방법
CN110964029B (zh) * 2019-12-19 2020-11-03 鲁南制药集团股份有限公司 一种埃博霉素b发酵液的预处理方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4138042C2 (de) * 1991-11-19 1993-10-14 Biotechnolog Forschung Gmbh Epothilone, deren Herstellungsverfahren sowie diese Verbindungen enthaltende Mittel
DK1367057T3 (da) * 1996-11-18 2009-01-19 Biotechnolog Forschung Gmbh Epothiloner E og F
DK1001951T3 (da) * 1997-07-16 2002-12-23 Schering Ag Thiazolderivater, fremgangsmåde til fremstilling deraf og anvendelse af disse
US6365749B1 (en) * 1997-12-04 2002-04-02 Bristol-Myers Squibb Company Process for the preparation of ring-opened epothilone intermediates which are useful for the preparation of epothilone analogs
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
DE19826988A1 (de) * 1998-06-18 1999-12-23 Biotechnolog Forschung Gmbh Epothilon-Nebenkomponenten
MXPA02010565A (es) * 2000-04-28 2004-05-17 Kosan Biosciences Inc Produccion de policetidos.
GB0029895D0 (en) * 2000-12-07 2001-01-24 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
EP1345944B1 (en) 2005-03-30
CN1263761C (zh) 2006-07-12
PE20020568A1 (es) 2002-07-22
PL361884A1 (pl) 2004-10-04
DE60109814D1 (de) 2005-05-04
MXPA03005097A (es) 2003-09-05
DK1345944T3 (da) 2005-05-30
ZA200304296B (en) 2004-04-23
PL209406B1 (pl) 2011-08-31
SK287356B6 (sk) 2010-08-09
NO329164B1 (no) 2010-09-06
HUP0302579A3 (en) 2004-10-28
US20050288514A1 (en) 2005-12-29
HK1059618A1 (en) 2004-07-09
CZ20031565A3 (cs) 2003-10-15
AU2002224936B2 (en) 2005-09-22
AU2493602A (en) 2002-06-18
HUP0302579A2 (hu) 2003-11-28
NZ526197A (en) 2005-01-28
JP2004521879A (ja) 2004-07-22
ES2239687T3 (es) 2005-10-01
SK6892003A3 (en) 2004-01-08
MY128409A (en) 2007-01-31
HU224910B1 (en) 2006-04-28
ECSP034641A (es) 2003-07-25
NO20032591D0 (no) 2003-06-06
EP1345944A1 (en) 2003-09-24
SI1345944T1 (sl) 2005-12-31
US6946561B2 (en) 2005-09-20
AR031902A1 (es) 2003-10-08
US7569698B2 (en) 2009-08-04
TWI286137B (en) 2007-09-01
US20040054188A1 (en) 2004-03-18
KR100894990B1 (ko) 2009-04-24
CA2433414A1 (en) 2002-06-13
CA2433414C (en) 2011-01-25
CZ301664B6 (cs) 2010-05-19
WO2002046196A1 (en) 2002-06-13
RU2285007C2 (ru) 2006-10-10
IL156088A0 (en) 2003-12-23
IL156088A (en) 2008-08-07
DE60109814T2 (de) 2006-02-16
PT1345944E (pt) 2005-08-31
ATE292132T1 (de) 2005-04-15
JP4287650B2 (ja) 2009-07-01
BR0115991A (pt) 2004-01-13
KR20030053535A (ko) 2003-06-28
NO20032591L (no) 2003-06-06
CN1479741A (zh) 2004-03-03

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)