FR2823764B1 - Nouveaux polynucleotides et polypeptides du gene ifn alpha-17 - Google Patents
Nouveaux polynucleotides et polypeptides du gene ifn alpha-17Info
- Publication number
- FR2823764B1 FR2823764B1 FR0105516A FR0105516A FR2823764B1 FR 2823764 B1 FR2823764 B1 FR 2823764B1 FR 0105516 A FR0105516 A FR 0105516A FR 0105516 A FR0105516 A FR 0105516A FR 2823764 B1 FR2823764 B1 FR 2823764B1
- Authority
- FR
- France
- Prior art keywords
- gene
- polypeptides
- ifn alpha
- novel polynucleotides
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 2
- 102000040430 polynucleotide Human genes 0.000 title abstract 2
- 108091033319 polynucleotide Proteins 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 230000035772 mutation Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- C12Q2600/00—Oligonucleotides characterized by their use
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Virology (AREA)
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0105516A FR2823764B1 (fr) | 2001-04-24 | 2001-04-24 | Nouveaux polynucleotides et polypeptides du gene ifn alpha-17 |
CNA028102193A CN1509337A (zh) | 2001-04-24 | 2002-04-23 | IFNα-17基因的新的多核苷酸和多肽 |
JP2002583669A JP2004533240A (ja) | 2001-04-24 | 2002-04-23 | IFNα−17遺伝子の新規のポリヌクレオチドおよびポリペプチド |
DE60213402T DE60213402T2 (de) | 2001-04-24 | 2002-04-23 | Neue polynukleotide und polypeptide des ifn alpha-17-gens |
IL15841502A IL158415A0 (en) | 2001-04-24 | 2002-04-23 | NEW POLYNUCLEOTIDES AND POLYPEPTIDES OF THE IFNalpha-17 GENE |
RU2003133982/13A RU2328528C2 (ru) | 2001-04-24 | 2002-04-23 | Полипептид, обладающий противовирусной, антипролиферативной и/или иммуномодулирующей активностью, выделенный полинуклеотид, кодирующий полипептид и их применение |
NZ529051A NZ529051A (en) | 2001-04-24 | 2002-04-23 | New polynucleotides and polypeptides of the IFNalpha-17 gene |
ES02742996T ES2268054T3 (es) | 2001-04-24 | 2002-04-23 | Nuevos polinucleotidos y polipeptidos del gen ifnalfa-17. |
AU2002338442A AU2002338442B2 (en) | 2001-04-24 | 2002-04-23 | New polynucleotides and polypeptides of the IFN alpha-17 gene |
EP02742996A EP1390543B1 (en) | 2001-04-24 | 2002-04-23 | New polynucleotides and polypeptides of the ifnalpha-17 gene |
BR0209097-0A BR0209097A (pt) | 2001-04-24 | 2002-04-23 | Polinucleotìdeo isolado, métodos para identificar ou amplificar e para a genotipagem de todo ou parte de um polinucleotìdeo, para separar um polipeptìdeo, para obter um anticorpo imunoespecìfico, para identificar um agente e um composto entre um ou mais compostos a serem testados, para analisar as caracterìsticas biológicas de um paciente, para impedir ou tratar em um indivìduo uma doença e um distúrbio ou uma doença ligada à presença do polinucleotìdeo no genoma, para aumentar ou diminuir a atividade em um paciente do polipeptìdeo, para determinar estatisticamente associações relevantes entre pelo menos um snp e uma doença ou resistência à doença e para diagnosticar ou determinar um prognóstico de uma doença ou uma resistência a uma doença, vetor recombinante, célula hospedeira, polipeptìdeo, anticorpo imunoespecìfico, agente terapêutico, e, composto |
AT02742996T ATE334231T1 (de) | 2001-04-24 | 2002-04-23 | Neue polynukleotide und polypeptide des ifn alpha-17-gens |
PT02742996T PT1390543E (pt) | 2001-04-24 | 2002-04-23 | Novos polinucleótidos e polipéptidos do gene ifna-17 |
CA002444235A CA2444235A1 (en) | 2001-04-24 | 2002-04-23 | New polynucleotides and polypeptides of the ifn.alpha.-17 gene |
KR10-2003-7013862A KR20030093328A (ko) | 2001-04-24 | 2002-04-23 | IFNα-17 유전자의 신규한 폴리뉴클레오티드 및폴리펩티드 |
PCT/EP2002/005229 WO2002086156A2 (en) | 2001-04-24 | 2002-04-23 | New polynucleotides and polypeptides of the ifn$g(a)-17 gene |
DK02742996T DK1390543T3 (da) | 2001-04-24 | 2002-04-23 | Nye polynukleotider og polypeptider af IFNalfa-17-genet |
MXPA03009731A MXPA03009731A (es) | 2001-04-24 | 2002-04-23 | Polinucleotidos y polipeptidos novedosos del gen de ifnalfa-17. |
IL158415A IL158415A (en) | 2001-04-24 | 2003-10-14 | Polynucleotides and polypeptides of the 17th-INF gene |
ZA200308114A ZA200308114B (en) | 2001-04-24 | 2003-10-17 | New polynucleotides and polypeptides of the IFNalpha-17 gene. |
NO20034692A NO20034692L (no) | 2001-04-24 | 2003-10-20 | Nye polynukleotider og polypeptider av INF gamma-17 genet |
US10/691,653 US7371819B2 (en) | 2001-04-24 | 2003-10-24 | Polypeptides of the IFNα-17 gene |
CY20061101453T CY1107335T1 (el) | 2001-04-24 | 2006-10-12 | ΝΕΑ ΠΟΛΥΝΟΥΚΛΕΟΤΙΔΙΑ ΚΑΙ ΠΟΛΥΠΕΠΤΙΔΙΑ ΤΟΥ ΓΟΝΙΔΙΟΥ IFNα-17 |
US12/098,557 US20090004156A1 (en) | 2001-04-24 | 2008-04-07 | POLYNUCLEOTIDES AND POLYPEPTIDES OF THE IFNalpha17 GENE |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0105516A FR2823764B1 (fr) | 2001-04-24 | 2001-04-24 | Nouveaux polynucleotides et polypeptides du gene ifn alpha-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2823764A1 FR2823764A1 (fr) | 2002-10-25 |
FR2823764B1 true FR2823764B1 (fr) | 2003-12-12 |
Family
ID=8862643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0105516A Expired - Fee Related FR2823764B1 (fr) | 2001-04-24 | 2001-04-24 | Nouveaux polynucleotides et polypeptides du gene ifn alpha-17 |
Country Status (22)
Country | Link |
---|---|
US (2) | US7371819B2 (no) |
EP (1) | EP1390543B1 (no) |
JP (1) | JP2004533240A (no) |
KR (1) | KR20030093328A (no) |
CN (1) | CN1509337A (no) |
AT (1) | ATE334231T1 (no) |
AU (1) | AU2002338442B2 (no) |
BR (1) | BR0209097A (no) |
CA (1) | CA2444235A1 (no) |
CY (1) | CY1107335T1 (no) |
DE (1) | DE60213402T2 (no) |
DK (1) | DK1390543T3 (no) |
ES (1) | ES2268054T3 (no) |
FR (1) | FR2823764B1 (no) |
IL (2) | IL158415A0 (no) |
MX (1) | MXPA03009731A (no) |
NO (1) | NO20034692L (no) |
NZ (1) | NZ529051A (no) |
PT (1) | PT1390543E (no) |
RU (1) | RU2328528C2 (no) |
WO (1) | WO2002086156A2 (no) |
ZA (1) | ZA200308114B (no) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
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US7087726B2 (en) | 2001-02-22 | 2006-08-08 | Genentech, Inc. | Anti-interferon-α antibodies |
US8551469B2 (en) | 2001-02-28 | 2013-10-08 | Superlab Far East Limited | Treatment of tumors and viral diseases with recombinant interferon alpha |
FR2822845B1 (fr) * | 2001-03-30 | 2003-12-12 | Genodyssee | Nouveaux polynucleotides comportant des polymorphismes de type snp fonctionnels dans la sequence nucleotidique du gene ifn-alpha-21 ainsi que de nouveaux polypeptides codes par ces polynucleotides et leurs utilisations therapeutiques |
EP1418428A1 (en) * | 2002-11-07 | 2004-05-12 | GenOdyssee | Method to provide natural therapeutic agents with high therapeutic index |
CN102101886A (zh) * | 2009-12-18 | 2011-06-22 | 四川辉阳生命工程股份有限公司 | 构象改变的重组干扰素晶体、其三维结构及应用 |
KR102096224B1 (ko) | 2011-10-28 | 2020-04-03 | 테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 | 폴리펩티드 구축물 및 이의 용도 |
TWI718086B (zh) | 2013-01-07 | 2021-02-11 | 英屬維爾京群島商遠東超級實驗室有限公司 | 通過干擾素的經皮和/或經粘膜給藥治療骨癌、皮膚癌、皮下癌、粘膜癌和/或粘膜下癌的方法和組合物 |
MX370377B (es) | 2013-04-29 | 2019-12-11 | Teva Pharmaceuticals Australia Pty Ltd | Anticuerpos anti-cd38 y fusiones con interferón alfa-2b atenuado. |
US11117975B2 (en) | 2013-04-29 | 2021-09-14 | Teva Pharmaceuticals Australia Pty Ltd | Anti-CD38 antibodies and fusions to attenuated interferon alpha-2B |
UA119352C2 (uk) | 2014-05-01 | 2019-06-10 | Тева Фармасьютикалз Острейліа Пті Лтд | Комбінація леналідоміду або помалідоміду і конструкції анти-cd38 антитіло-атенуйований інтерферон альфа-2b та спосіб лікування суб'єкта, який має cd38-експресуючу пухлину |
JP6730271B2 (ja) | 2014-10-29 | 2020-07-29 | テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド | インターフェロンα2Bバリアント |
RU2620073C2 (ru) * | 2015-06-02 | 2017-05-22 | Федеральное государственное бюджетное учреждение "Государственный научный центр Институт иммунологии" Федерального медико-биологического агентства России | Оптимизированный ген, кодирующий рекомбинантный белок - аналог интерферона альфа-17 человека |
CN107653323B (zh) * | 2016-07-23 | 2021-05-04 | 华中农业大学 | 团头鲂转铁蛋白基因snp分子标记及其应用 |
US20210380679A1 (en) | 2018-10-11 | 2021-12-09 | Inhibrx, Inc. | Dll3 single domain antibodies and therapeutic compositions thereof |
US20230124851A1 (en) | 2018-10-11 | 2023-04-20 | Inhibrx, lnc. | B7h3 single domain antibodies and therapeutic compositions thereof |
CA3114693A1 (en) | 2018-10-11 | 2020-04-16 | Inhibrx, Inc. | 5t4 single domain antibodies and therapeutic compositions thereof |
AU2019356573A1 (en) | 2018-10-11 | 2021-05-27 | Inhibrx Biosciences, Inc. | PD-1 single domain antibodies and therapeutic compositions thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
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US4801685A (en) * | 1981-08-14 | 1989-01-31 | Hoffmann-La Roche Inc. | Microbial production of mature human leukocyte interferon K and L |
JPS6156199A (ja) * | 1984-08-27 | 1986-03-20 | Shionogi & Co Ltd | 新規ヒトインタ−フエロンα類 |
JP3732516B2 (ja) * | 1995-02-09 | 2006-01-05 | ノバルティス・アクチエンゲゼルシャフト | タンパク質の製造法 |
AU761577C (en) * | 1997-12-08 | 2004-02-05 | Genentech Inc. | Human interferon-epsilon: a type I interferon |
EP1140144A4 (en) * | 1998-12-31 | 2002-10-30 | Viragen Inc | METHODS AND COMPOSITION OF EXTREMELY PURIFIED NATURAL MIXTURES OF TYPE I INTERFERONS DERIVED FROM LEUCOCYTES |
CN1451045A (zh) * | 1999-10-07 | 2003-10-22 | 马克西根公司 | IFN-α同系物 |
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Also Published As
Publication number | Publication date |
---|---|
FR2823764A1 (fr) | 2002-10-25 |
US7371819B2 (en) | 2008-05-13 |
RU2328528C2 (ru) | 2008-07-10 |
NZ529051A (en) | 2005-09-30 |
NO20034692L (no) | 2003-12-19 |
IL158415A0 (en) | 2004-05-12 |
BR0209097A (pt) | 2005-04-19 |
ZA200308114B (en) | 2005-01-17 |
KR20030093328A (ko) | 2003-12-06 |
DE60213402D1 (de) | 2006-09-07 |
JP2004533240A (ja) | 2004-11-04 |
WO2002086156A3 (en) | 2003-11-27 |
EP1390543B1 (en) | 2006-07-26 |
EP1390543A2 (en) | 2004-02-25 |
ES2268054T3 (es) | 2007-03-16 |
CA2444235A1 (en) | 2002-10-31 |
MXPA03009731A (es) | 2005-03-07 |
NO20034692D0 (no) | 2003-10-20 |
DK1390543T3 (da) | 2006-11-27 |
CN1509337A (zh) | 2004-06-30 |
AU2002338442B8 (en) | 2002-11-05 |
PT1390543E (pt) | 2006-12-29 |
WO2002086156A2 (en) | 2002-10-31 |
US20090004156A1 (en) | 2009-01-01 |
CY1107335T1 (el) | 2012-12-19 |
ATE334231T1 (de) | 2006-08-15 |
AU2002338442B2 (en) | 2007-06-28 |
IL158415A (en) | 2009-06-15 |
RU2003133982A (ru) | 2005-01-20 |
US20040110715A1 (en) | 2004-06-10 |
DE60213402T2 (de) | 2007-08-23 |
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