EP1140144A4 - Composition of highly purified natural mixtures of type i interferon derived from leukocytes and methods - Google Patents

Composition of highly purified natural mixtures of type i interferon derived from leukocytes and methods

Info

Publication number
EP1140144A4
EP1140144A4 EP99967753A EP99967753A EP1140144A4 EP 1140144 A4 EP1140144 A4 EP 1140144A4 EP 99967753 A EP99967753 A EP 99967753A EP 99967753 A EP99967753 A EP 99967753A EP 1140144 A4 EP1140144 A4 EP 1140144A4
Authority
EP
European Patent Office
Prior art keywords
leukocytes
composition
methods
type
highly purified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99967753A
Other languages
German (de)
French (fr)
Other versions
EP1140144A2 (en
Inventor
Joseph P Morris
Duy Nguyen
James Kappelman
Mead M Mccabe
Michael D Potter
M Reza Ziai
Stephen Feldman
Hipolito Hartman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Viragen Inc
Original Assignee
Viragen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/224,895 external-priority patent/US6350589B1/en
Priority claimed from US09/229,039 external-priority patent/US6433144B1/en
Application filed by Viragen Inc filed Critical Viragen Inc
Publication of EP1140144A2 publication Critical patent/EP1140144A2/en
Publication of EP1140144A4 publication Critical patent/EP1140144A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
EP99967753A 1998-12-31 1999-12-29 Composition of highly purified natural mixtures of type i interferon derived from leukocytes and methods Withdrawn EP1140144A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US224895 1988-07-27
US09/224,895 US6350589B1 (en) 1998-12-31 1998-12-31 Compositions of highly-purified natural mixtures of type I interferon derived from leukocytes and methods
US09/229,039 US6433144B1 (en) 1999-01-12 1999-01-12 Compositions of highly-purified natural mixtures of type I Interferon derived from leukocytes and methods
US229039 1999-01-12
PCT/US1999/031198 WO2000039280A2 (en) 1998-12-31 1999-12-29 Leukocyte-derived interferon preparations

Publications (2)

Publication Number Publication Date
EP1140144A2 EP1140144A2 (en) 2001-10-10
EP1140144A4 true EP1140144A4 (en) 2002-10-30

Family

ID=26919102

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99967753A Withdrawn EP1140144A4 (en) 1998-12-31 1999-12-29 Composition of highly purified natural mixtures of type i interferon derived from leukocytes and methods

Country Status (2)

Country Link
EP (1) EP1140144A4 (en)
WO (1) WO2000039280A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL155730A0 (en) 2000-11-03 2003-11-23 Biomedicines Inc Method for short-term and long-term drug dosimetry
FR2822845B1 (en) * 2001-03-30 2003-12-12 Genodyssee NOVEL POLYNUCLEOTIDES COMPRISING FUNCTIONAL SNP-LIKE POLYMORPHISMS IN THE NUCLEOTIDE SEQUENCE OF THE IFN-ALPHA-21 GENE AS WELL AS NEW POLYPEPTIDES ENCODED BY THESE POLYNUCLEOTIDES AND THEIR THERAPEUTIC USES
FR2823764B1 (en) * 2001-04-24 2003-12-12 Genodyssee NOVEL POLYNUCLEOTIDES AND POLYPEPTIDES OF THE IFN ALPHA-17 GENE
FR2825716B1 (en) * 2001-06-11 2004-09-24 Genodyssee NOVEL POLYNUCLEOTIDES AND POLYPEPTIDES FROM IFN ALPHA 7
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
CA2597754A1 (en) * 2005-02-12 2006-08-17 Viranative Ab Methods and uses of antibodies in the purification of interferon
MX2008014870A (en) 2006-05-30 2009-02-12 Intarcia Therapeutics Inc Two-piece, internal-channel osmotic delivery system flow modulator.
EP3421031A1 (en) 2006-08-09 2019-01-02 Intarcia Therapeutics, Inc Osmotic delivery systems and piston assemblies
CN101715340A (en) 2007-04-23 2010-05-26 精达制药公司 The mixed suspension preparation of insulinotropic peptide and application thereof
EP2240155B1 (en) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Devices, formulations, and methods for delivery of multiple beneficial agents
SI2462246T1 (en) 2009-09-28 2018-01-31 Intarcia Therapeutics, Inc. Rapid establishment and/or termination of substantial steady-state drug delivery
RU2482871C2 (en) * 2010-06-07 2013-05-27 Общество с ограниченной ответственностью "Центр Инновационных Технологий "БиоФарм" (ООО "ЦИТ "БиоФарм") Composition for treating viral diseases in animals
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
KR102650751B1 (en) 2015-06-03 2024-03-22 인타르시아 세라퓨틱스 인코포레이티드 Implant placement and removal systems
SG10201913699QA (en) 2016-05-16 2020-03-30 Intarcia Therapeutics Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
AU2018206539A1 (en) 2017-01-03 2019-07-18 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4732683A (en) * 1986-12-02 1988-03-22 Biospectrum, Inc. Purification method for alpha interferon
WO1993016107A1 (en) * 1992-02-10 1993-08-19 Interferon Sciences, Inc. Improved alpha interferon composition and method for its production from human peripheral blood leukocytes
EP0626448A2 (en) * 1993-05-26 1994-11-30 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Process for preparing and purifying alpha-interferon
EP0679718A2 (en) * 1994-04-09 1995-11-02 F. Hoffmann-La Roche AG Process for producing alpha-interferon

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5676942A (en) * 1992-02-10 1997-10-14 Interferon Sciences, Inc. Composition containing human alpha interferon species proteins and method for use thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4732683A (en) * 1986-12-02 1988-03-22 Biospectrum, Inc. Purification method for alpha interferon
WO1993016107A1 (en) * 1992-02-10 1993-08-19 Interferon Sciences, Inc. Improved alpha interferon composition and method for its production from human peripheral blood leukocytes
EP0626448A2 (en) * 1993-05-26 1994-11-30 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Process for preparing and purifying alpha-interferon
EP0679718A2 (en) * 1994-04-09 1995-11-02 F. Hoffmann-La Roche AG Process for producing alpha-interferon

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
KANDEFER-SZERSZEN MARTYNA ET AL: "Influence of the perinatal period on bovine interferon production.", ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, vol. 42, no. 4, 1994, pages 307 - 311, XP001088148, ISSN: 0004-069X *
MULLICK ASHIM ET AL: "Comparison of fluoride modified zirconia with ceramic hydroxyapatite for preparative scale purification of immunoglobulin from serum albumin.", PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, vol. 28, no. 1, February 1998 (1998-02-01), pages 1 - 21, XP001088247, ISSN: 1082-6068 *
See also references of WO0039280A3 *
SHIRONO H ET AL: "STUDIES ON SUBTYPE COMPOSITION IN NATURAL LEUKOCYTE INTERFERON PREPARATIONS", JOURNAL OF VIROLOGICAL METHODS, vol. 27, no. 1, 1990, pages 1 - 10, XP001087823, ISSN: 0166-0934 *
SHIRONO H ET AL: "STUDY ON SUBTYPE COMPOSITION OF PURIFIED HUMAN LEUKOCYTE INTERFERON FOR CLINICAL USE", JOURNAL OF INTERFERON RESEARCH, vol. 8, no. SUPPL. 1, 1988, pages S62, XP001084337, ISSN: 0197-8357 *
SHIRONO HIROYUKI ET AL: "Identification of Glycosylated Subtypes of Interferon-alpha Produced by Human Leukocytes.", BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, vol. 58, no. 9, 1994, pages 1714 - 1715, XP001087825, ISSN: 0916-8451 *

Also Published As

Publication number Publication date
WO2000039280A3 (en) 2001-07-19
WO2000039280A8 (en) 2000-10-19
EP1140144A2 (en) 2001-10-10
WO2000039280A2 (en) 2000-07-06

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Inventor name: HARTMAN, HIPOLITO

Inventor name: FELDMAN, STEPHEN

Inventor name: ZIAI, M., REZA

Inventor name: POTTER, MICHAEL, D.

Inventor name: MCCABE, MEAD, M.

Inventor name: KAPPELMAN, JAMES

Inventor name: NGUYEN, DUY

Inventor name: MORRIS, JOSEPH, P.

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