DE60235297D1 - Auf lps-reagierendes chs1/beige-ähnliches anker-gen und therapeutische anwendungen davon - Google Patents

Auf lps-reagierendes chs1/beige-ähnliches anker-gen und therapeutische anwendungen davon

Info

Publication number
DE60235297D1
DE60235297D1 DE60235297T DE60235297T DE60235297D1 DE 60235297 D1 DE60235297 D1 DE 60235297D1 DE 60235297 T DE60235297 T DE 60235297T DE 60235297 T DE60235297 T DE 60235297T DE 60235297 D1 DE60235297 D1 DE 60235297D1
Authority
DE
Germany
Prior art keywords
lrba
beige
lps
chs1
resistant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60235297T
Other languages
English (en)
Inventor
William G Kerr
Jia-Wang Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of South Florida
Original Assignee
University of South Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of South Florida filed Critical University of South Florida
Application granted granted Critical
Publication of DE60235297D1 publication Critical patent/DE60235297D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE60235297T 2001-04-02 2002-04-02 Auf lps-reagierendes chs1/beige-ähnliches anker-gen und therapeutische anwendungen davon Expired - Lifetime DE60235297D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28010701P 2001-04-02 2001-04-02
PCT/US2002/010350 WO2002078614A2 (en) 2001-04-02 2002-04-02 Lps-responsive chs1/beige-like anchor gene and therapeutic applications thereof

Publications (1)

Publication Number Publication Date
DE60235297D1 true DE60235297D1 (de) 2010-03-25

Family

ID=23071704

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60235297T Expired - Lifetime DE60235297D1 (de) 2001-04-02 2002-04-02 Auf lps-reagierendes chs1/beige-ähnliches anker-gen und therapeutische anwendungen davon

Country Status (7)

Country Link
US (2) US7704963B2 (de)
EP (1) EP1383924B1 (de)
AT (1) ATE457359T1 (de)
AU (1) AU2002303214A1 (de)
CA (1) CA2443338A1 (de)
DE (1) DE60235297D1 (de)
WO (1) WO2002078614A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7691821B2 (en) * 2001-09-19 2010-04-06 University Of South Florida Inhibition of SHIP to enhance stem cell harvest and transplantation
US20020165192A1 (en) * 2000-09-19 2002-11-07 Kerr William G. Control of NK cell function and survival by modulation of ship activity
WO2002078614A2 (en) * 2001-04-02 2002-10-10 University Of South Florida Lps-responsive chs1/beige-like anchor gene and therapeutic applications thereof
US8440395B2 (en) * 2001-04-02 2013-05-14 University Of South Florida Methods of detecting and treating colon disorders
DE10229872A1 (de) * 2002-07-03 2004-01-29 Curevac Gmbh Immunstimulation durch chemisch modifizierte RNA
US20070224124A1 (en) * 2002-09-30 2007-09-27 University Of South Florida Novel SH2containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein
EP1554408A2 (de) * 2002-10-25 2005-07-20 Oncotherapy Science, Inc. Methode zur diagnose von undifferenziertem magenkrebs
US7763592B1 (en) 2003-11-20 2010-07-27 University Of South Florida SHIP-deficiency to increase megakaryocyte progenitor production
US7807646B1 (en) * 2003-11-20 2010-10-05 University Of South Florida SHIP-deficiency to increase megakaryocyte progenitor production
WO2007011819A2 (en) * 2005-07-15 2007-01-25 The Penn State Research Foundation Ferritin as a therapeutic target in abnormal cells
AU2007280690C1 (en) 2006-07-31 2012-08-23 Curevac Gmbh Nucleic acid of formula (I): GIXmGn, or (II): CIXmCn, in particular as an immune-stimulating agent/adjuvant
WO2009030254A1 (en) 2007-09-04 2009-03-12 Curevac Gmbh Complexes of rna and cationic peptides for transfection and for immunostimulation
EP2548960B1 (de) 2008-01-31 2018-01-31 CureVac AG Nukleinsäure der Formel (NuGIXmGnNv)a und Derivate davon als immunstimulierendes Mittel/Adjuvans
WO2010037408A1 (en) 2008-09-30 2010-04-08 Curevac Gmbh Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
US20110053829A1 (en) 2009-09-03 2011-03-03 Curevac Gmbh Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
CA2801523C (en) 2010-07-30 2021-08-03 Curevac Gmbh Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
WO2013113326A1 (en) 2012-01-31 2013-08-08 Curevac Gmbh Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
US9738706B2 (en) * 2013-03-22 2017-08-22 University Of South Florida Inflammatory disease diagnosis and methods of treatment using lipopolysaccharides-responsive beige-like anchor
AU2014310934B2 (en) 2013-08-21 2019-09-12 CureVac SE Respiratory syncytial virus (RSV) vaccine
EP3129050A2 (de) 2014-04-01 2017-02-15 CureVac AG Polymerträger-cargo-komplex zur verwendung als immunstimulierendes mittel oder als ein adjuvans
WO2016168848A1 (en) 2015-04-17 2016-10-20 University Of South Florida Animal model and method for studying gene-gene interactions
CN105238875A (zh) * 2015-11-19 2016-01-13 湖南宏雅基因技术有限公司 基于lrba基因检测抗ctla-4抗体药物疗效的试剂盒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789214A (en) 1988-03-08 1998-08-04 Novartis Finance Corporation Method of inducing gene transcription in a plant
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
US5639949A (en) 1990-08-20 1997-06-17 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
JP3234598B2 (ja) 1990-11-23 2001-12-04 プラント・ジエネテイツク・システムズ・エヌ・ベー 単子葉植物の形質転換方法
US5593874A (en) 1992-03-19 1997-01-14 Monsanto Company Enhanced expression in plants
US5693512A (en) 1996-03-01 1997-12-02 The Ohio State Research Foundation Method for transforming plant tissue by sonication
WO2002078614A2 (en) * 2001-04-02 2002-10-10 University Of South Florida Lps-responsive chs1/beige-like anchor gene and therapeutic applications thereof
US8440395B2 (en) * 2001-04-02 2013-05-14 University Of South Florida Methods of detecting and treating colon disorders
US20110165566A1 (en) * 2009-07-09 2011-07-07 Wittliff James L Methods of optimizing treatment of breast cancer

Also Published As

Publication number Publication date
AU2002303214A1 (en) 2002-10-15
EP1383924A4 (de) 2005-06-15
EP1383924A2 (de) 2004-01-28
CA2443338A1 (en) 2002-10-10
ATE457359T1 (de) 2010-02-15
US20100266548A1 (en) 2010-10-21
WO2002078614A2 (en) 2002-10-10
EP1383924B1 (de) 2010-02-10
US7704963B2 (en) 2010-04-27
US20040235765A1 (en) 2004-11-25
WO2002078614A3 (en) 2003-03-20

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