FR2690847B1 - Compositions a activite agoniste des recepteurs analogues a 5ht1 selective. - Google Patents

Compositions a activite agoniste des recepteurs analogues a 5ht1 selective.

Info

Publication number
FR2690847B1
FR2690847B1 FR9305432A FR9305432A FR2690847B1 FR 2690847 B1 FR2690847 B1 FR 2690847B1 FR 9305432 A FR9305432 A FR 9305432A FR 9305432 A FR9305432 A FR 9305432A FR 2690847 B1 FR2690847 B1 FR 2690847B1
Authority
FR
France
Prior art keywords
pct
selective
compositions
agonist activity
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9305432A
Other languages
English (en)
French (fr)
Other versions
FR2690847A1 (fr
Inventor
Merlet Nadine
Richard Isabelle
Thielemans Isabelle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Glaxo Wellcome SA
Original Assignee
Laboratoires Glaxo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Glaxo SA filed Critical Laboratoires Glaxo SA
Publication of FR2690847A1 publication Critical patent/FR2690847A1/fr
Application granted granted Critical
Publication of FR2690847B1 publication Critical patent/FR2690847B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
FR9305432A 1992-05-07 1993-05-06 Compositions a activite agoniste des recepteurs analogues a 5ht1 selective. Expired - Lifetime FR2690847B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929209882A GB9209882D0 (en) 1992-05-07 1992-05-07 Compositions

Publications (2)

Publication Number Publication Date
FR2690847A1 FR2690847A1 (fr) 1993-11-12
FR2690847B1 true FR2690847B1 (fr) 1995-06-09

Family

ID=10715158

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9305432A Expired - Lifetime FR2690847B1 (fr) 1992-05-07 1993-05-06 Compositions a activite agoniste des recepteurs analogues a 5ht1 selective.

Country Status (33)

Country Link
US (1) US5705506A (enExample)
EP (1) EP0639072B1 (enExample)
JP (1) JPH07506570A (enExample)
KR (1) KR100253111B1 (enExample)
AT (1) ATE163850T1 (enExample)
AU (1) AU670083B2 (enExample)
BE (1) BE1007024A5 (enExample)
BG (1) BG62120B1 (enExample)
BR (1) BR1100108A (enExample)
CA (1) CA2135179C (enExample)
CH (1) CH685920A5 (enExample)
CY (1) CY2039B1 (enExample)
CZ (1) CZ283512B6 (enExample)
DE (1) DE69317418T2 (enExample)
ES (1) ES2113533T3 (enExample)
FR (1) FR2690847B1 (enExample)
GB (2) GB9209882D0 (enExample)
GR (1) GR3026584T3 (enExample)
HK (1) HK95697A (enExample)
HU (2) HU227338B1 (enExample)
IE (1) IE75203B1 (enExample)
IL (1) IL105468A (enExample)
IT (1) IT1261471B (enExample)
NO (1) NO306700B1 (enExample)
NZ (1) NZ252132A (enExample)
OA (1) OA10109A (enExample)
RO (1) RO112993B1 (enExample)
RU (1) RU2118527C1 (enExample)
SG (1) SG46649A1 (enExample)
TW (1) TW231970B (enExample)
UA (1) UA37206C2 (enExample)
WO (1) WO1993021916A1 (enExample)
ZA (1) ZA933178B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2434297A (en) * 1996-05-23 1997-12-09 Alcon Laboratories, Inc. The use of 5-ht1b/1d agonists to treat ocular pain
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
ME00189B (me) * 1998-03-26 2011-02-10 Astellas Pharma Inc Preparati sa neprekidnim oslobađanjem
AU3731400A (en) * 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Methods and compositions useful in inhibiting apoptosis
AR056690A1 (es) * 2005-10-14 2007-10-17 Athersys Inc Derivados de indol como inhibidores de indol como inhibidores del receptor 3 de histamina para el tartamiento de trastornos del sueno y cognitivos obesidad y otros trastornos de snc
SI2124556T1 (sl) 2006-10-09 2015-01-30 Charleston Laboratories, Inc. Farmacevtske sestave
EP3090743A1 (en) 2008-01-09 2016-11-09 Charleston Laboratories, Inc. Pharmaceutical compositions for treating headache and eliminating nausea
CA2767576C (en) 2009-07-08 2020-03-10 Charleston Laboratories Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
SI2627328T1 (sl) 2010-10-15 2017-01-31 Contera Pharma Aps Kombinacije agonistov receptorjev serotonina za zdravljenje motenj premikanja
CN104411301B (zh) 2012-04-18 2018-02-06 康特拉医药公司 适于改善运动障碍治疗的口服药物配方
CA3055170A1 (en) 2016-03-04 2017-09-08 Charleston Laboratories, Inc. Pharmaceutical compositions
AU2017297718B2 (en) 2016-07-11 2023-06-08 Contera Pharma A/S Pulsatile drug delivery system for treating morning akinesia

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE454777B (sv) * 1980-08-12 1988-05-30 Glaxo Group Ltd 5-substituerade 3-aminoalkyl-1h-indoler, forfarande for framstellning av dessa och en farmaceutisk komposition for behandling av migren
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
IT1170387B (it) * 1982-06-07 1987-06-03 Glaxo Group Ltd Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
GB8332435D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
IT1181741B (it) * 1984-12-04 1987-09-30 Glaxo Group Ltd Derivati di indolo,procedimento per prepararli e composizioni farmaceutiche che li contengono
GB8431426D0 (en) * 1984-12-13 1985-01-23 Glaxo Group Ltd Chemical compounds
US4833153A (en) * 1985-11-08 1989-05-23 Glaxo Group Limited Indole derivatives
AU611469B2 (en) * 1987-08-13 1991-06-13 Glaxo Group Limited Indole derivatives
PT97888B (pt) * 1990-06-07 1998-12-31 Zeneca Ltd Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem

Also Published As

Publication number Publication date
HU211638A9 (en) 1995-12-28
HK95697A (en) 1997-08-08
EP0639072B1 (en) 1998-03-11
ITRM930286A0 (it) 1993-05-06
RO112993B1 (ro) 1998-03-30
GB9209882D0 (en) 1992-06-24
IL105468A0 (en) 1993-08-18
AU670083B2 (en) 1996-07-04
EP0639072A1 (en) 1995-02-22
WO1993021916A1 (en) 1993-11-11
ITRM930286A1 (it) 1994-11-06
ZA933178B (en) 1994-01-10
HUT71418A (en) 1995-11-28
TW231970B (enExample) 1994-10-11
CH685920A5 (fr) 1995-11-15
GB9309209D0 (en) 1993-06-16
ATE163850T1 (de) 1998-03-15
NO944214L (no) 1994-11-07
OA10109A (en) 1996-12-18
KR100253111B1 (en) 2000-07-01
BE1007024A5 (fr) 1995-02-21
AU4064093A (en) 1993-11-29
DE69317418T2 (de) 1998-07-30
SG46649A1 (en) 1998-02-20
UA37206C2 (uk) 2001-05-15
FR2690847A1 (fr) 1993-11-12
BG62120B1 (bg) 1999-03-31
CA2135179A1 (en) 1993-11-11
GR3026584T3 (en) 1998-07-31
US5705506A (en) 1998-01-06
JPH07506570A (ja) 1995-07-20
IE930339A1 (en) 1993-11-17
NO306700B1 (no) 1999-12-13
CZ283512B6 (cs) 1998-04-15
RU2118527C1 (ru) 1998-09-10
HU227338B1 (en) 2011-04-28
DE69317418D1 (de) 1998-04-16
IE75203B1 (en) 1997-08-27
BR1100108A (pt) 1999-12-07
NZ252132A (en) 1996-09-25
GB2266665A (en) 1993-11-10
GB2266665B (en) 1996-05-22
CA2135179C (en) 2000-12-05
ES2113533T3 (es) 1998-05-01
NO944214D0 (no) 1994-11-04
CZ272394A3 (en) 1995-10-18
IL105468A (en) 1998-09-24
BG99167A (bg) 1995-06-30
IT1261471B (it) 1996-05-23
CY2039B1 (en) 1998-04-30

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