FR2513255A1 - Glycosides d'anthracycline, procede pour leur preparation et leur emploi comme medicament - Google Patents

Glycosides d'anthracycline, procede pour leur preparation et leur emploi comme medicament Download PDF

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Publication number
FR2513255A1
FR2513255A1 FR8215507A FR8215507A FR2513255A1 FR 2513255 A1 FR2513255 A1 FR 2513255A1 FR 8215507 A FR8215507 A FR 8215507A FR 8215507 A FR8215507 A FR 8215507A FR 2513255 A1 FR2513255 A1 FR 2513255A1
Authority
FR
France
Prior art keywords
doxorubicin
desamino
formula
compound according
daunorubicin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8215507A
Other languages
English (en)
French (fr)
Other versions
FR2513255B1 (enExample
Inventor
Giuseppe Cassinelli
Federico Arcamone
Anna Maria Casazza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of FR2513255A1 publication Critical patent/FR2513255A1/fr
Application granted granted Critical
Publication of FR2513255B1 publication Critical patent/FR2513255B1/fr
Granted legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR8215507A 1981-09-18 1982-09-14 Glycosides d'anthracycline, procede pour leur preparation et leur emploi comme medicament Granted FR2513255A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8128252 1981-09-18

Publications (2)

Publication Number Publication Date
FR2513255A1 true FR2513255A1 (fr) 1983-03-25
FR2513255B1 FR2513255B1 (enExample) 1984-11-30

Family

ID=10524593

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8215507A Granted FR2513255A1 (fr) 1981-09-18 1982-09-14 Glycosides d'anthracycline, procede pour leur preparation et leur emploi comme medicament

Country Status (24)

Country Link
JP (1) JPS5862184A (enExample)
KR (1) KR880001573B1 (enExample)
AU (1) AU549656B2 (enExample)
BE (1) BE894418A (enExample)
CA (1) CA1184903A (enExample)
CH (1) CH654014A5 (enExample)
CS (1) CS236682B2 (enExample)
DE (1) DE3233898A1 (enExample)
DK (1) DK157030C (enExample)
ES (1) ES8400120A1 (enExample)
FI (1) FI823169L (enExample)
FR (1) FR2513255A1 (enExample)
GR (1) GR77639B (enExample)
HU (1) HU186971B (enExample)
IE (1) IE53330B1 (enExample)
IL (1) IL66775A (enExample)
IT (1) IT1210481B (enExample)
NL (1) NL8203548A (enExample)
NO (1) NO153335C (enExample)
NZ (1) NZ201899A (enExample)
PT (1) PT75575B (enExample)
SE (1) SE456587B (enExample)
YU (1) YU204982A (enExample)
ZA (1) ZA826806B (enExample)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CARBOHYDRATE RESEARCH, volume 77, 1979, Elsevier Scientific Publishing Company, (AMSTERDAM, NL) D. HORTON et al. "Adriamycin analogs hydroxylated at C-3': synthesis and antitumor activity", pages C8-C11 *
JOURNAL OF MEDICINAL CHEMISTRY, volume 22, no. 4, 1979, American Chemical Society (US) E.F. FUCHS et al. "Synthesis and antitumor activity of sugar-ring hydroxyl analogues of daunorubicin", pages 406-408 *

Also Published As

Publication number Publication date
DE3233898C2 (enExample) 1988-01-28
DK157030C (da) 1990-04-02
CA1184903A (en) 1985-04-02
SE456587B (sv) 1988-10-17
HU186971B (en) 1985-10-28
IT1210481B (it) 1989-09-14
NZ201899A (en) 1985-09-13
SE8205288L (sv) 1983-03-19
ES515690A0 (es) 1983-10-16
CS236682B2 (en) 1985-05-15
PT75575B (en) 1984-12-10
FI823169A7 (fi) 1983-03-19
IE822246L (en) 1983-03-18
ZA826806B (en) 1983-07-27
JPS6260396B2 (enExample) 1987-12-16
AU8832382A (en) 1983-03-24
KR840001592A (ko) 1984-05-07
GR77639B (enExample) 1984-09-25
NL8203548A (nl) 1983-04-18
AU549656B2 (en) 1986-02-06
NO153335C (no) 1986-02-26
ES8400120A1 (es) 1983-10-16
SE8205288D0 (sv) 1982-09-15
KR880001573B1 (ko) 1988-08-23
NO823148L (no) 1983-03-21
YU204982A (en) 1985-03-20
FR2513255B1 (enExample) 1984-11-30
PT75575A (en) 1982-10-01
FI823169L (fi) 1983-03-19
DE3233898A1 (de) 1983-04-07
NO153335B (no) 1985-11-18
IT8223240A0 (it) 1982-09-14
IL66775A (en) 1986-11-30
DK411382A (da) 1983-03-19
FI823169A0 (fi) 1982-09-14
BE894418A (fr) 1983-01-17
JPS5862184A (ja) 1983-04-13
IL66775A0 (en) 1982-12-31
DK157030B (da) 1989-10-30
IE53330B1 (en) 1988-10-12
CH654014A5 (it) 1986-01-31

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