CS236682B2 - Manufacturing process of 3-deamine analogs of glycoside antheracyclic antibiotics - Google Patents

Manufacturing process of 3-deamine analogs of glycoside antheracyclic antibiotics Download PDF

Info

Publication number
CS236682B2
CS236682B2 CS826643A CS664382A CS236682B2 CS 236682 B2 CS236682 B2 CS 236682B2 CS 826643 A CS826643 A CS 826643A CS 664382 A CS664382 A CS 664382A CS 236682 B2 CS236682 B2 CS 236682B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
hydroxy
doxorubicin
glycoside
deamino
Prior art date
Application number
CS826643A
Other languages
Czech (cs)
English (en)
Inventor
Giuseppe Cassinelli
Federico Arcamone
Anna-Maria Casazza
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of CS236682B2 publication Critical patent/CS236682B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CS826643A 1981-09-18 1982-09-15 Manufacturing process of 3-deamine analogs of glycoside antheracyclic antibiotics CS236682B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8128252 1981-09-18

Publications (1)

Publication Number Publication Date
CS236682B2 true CS236682B2 (en) 1985-05-15

Family

ID=10524593

Family Applications (1)

Application Number Title Priority Date Filing Date
CS826643A CS236682B2 (en) 1981-09-18 1982-09-15 Manufacturing process of 3-deamine analogs of glycoside antheracyclic antibiotics

Country Status (24)

Country Link
JP (1) JPS5862184A (enExample)
KR (1) KR880001573B1 (enExample)
AU (1) AU549656B2 (enExample)
BE (1) BE894418A (enExample)
CA (1) CA1184903A (enExample)
CH (1) CH654014A5 (enExample)
CS (1) CS236682B2 (enExample)
DE (1) DE3233898A1 (enExample)
DK (1) DK157030C (enExample)
ES (1) ES8400120A1 (enExample)
FI (1) FI823169L (enExample)
FR (1) FR2513255A1 (enExample)
GR (1) GR77639B (enExample)
HU (1) HU186971B (enExample)
IE (1) IE53330B1 (enExample)
IL (1) IL66775A (enExample)
IT (1) IT1210481B (enExample)
NL (1) NL8203548A (enExample)
NO (1) NO153335C (enExample)
NZ (1) NZ201899A (enExample)
PT (1) PT75575B (enExample)
SE (1) SE456587B (enExample)
YU (1) YU204982A (enExample)
ZA (1) ZA826806B (enExample)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides

Also Published As

Publication number Publication date
DE3233898C2 (enExample) 1988-01-28
DK157030C (da) 1990-04-02
CA1184903A (en) 1985-04-02
SE456587B (sv) 1988-10-17
HU186971B (en) 1985-10-28
IT1210481B (it) 1989-09-14
NZ201899A (en) 1985-09-13
SE8205288L (sv) 1983-03-19
ES515690A0 (es) 1983-10-16
PT75575B (en) 1984-12-10
FI823169A7 (fi) 1983-03-19
IE822246L (en) 1983-03-18
ZA826806B (en) 1983-07-27
JPS6260396B2 (enExample) 1987-12-16
AU8832382A (en) 1983-03-24
KR840001592A (ko) 1984-05-07
GR77639B (enExample) 1984-09-25
FR2513255A1 (fr) 1983-03-25
NL8203548A (nl) 1983-04-18
AU549656B2 (en) 1986-02-06
NO153335C (no) 1986-02-26
ES8400120A1 (es) 1983-10-16
SE8205288D0 (sv) 1982-09-15
KR880001573B1 (ko) 1988-08-23
NO823148L (no) 1983-03-21
YU204982A (en) 1985-03-20
FR2513255B1 (enExample) 1984-11-30
PT75575A (en) 1982-10-01
FI823169L (fi) 1983-03-19
DE3233898A1 (de) 1983-04-07
NO153335B (no) 1985-11-18
IT8223240A0 (it) 1982-09-14
IL66775A (en) 1986-11-30
DK411382A (da) 1983-03-19
FI823169A0 (fi) 1982-09-14
BE894418A (fr) 1983-01-17
JPS5862184A (ja) 1983-04-13
IL66775A0 (en) 1982-12-31
DK157030B (da) 1989-10-30
IE53330B1 (en) 1988-10-12
CH654014A5 (it) 1986-01-31

Similar Documents

Publication Publication Date Title
US4672057A (en) Morpholino derivatives of daunorubicin and doxorubicin
CZ415191A3 (en) Anthracyclin glycoside
US4366149A (en) Antitumor anthracycline glycosides, their preparation, intermediates therefor, and compositions and use thereof
CA1291122C (en) 3'-hydroxy-4'-epi-amino anthracyclines
EP0014425B1 (en) Anthracycline glycosides, methods for the production thereof and therapeutical compositions containing same
US4199571A (en) Substituted anthracyclines, their preparation and use
US4169142A (en) Disaccharide analogs of antitumor anthracyclines, process for their preparation and use thereof
Israel et al. Adriamycin analogs. 1. Preparation and antitumor evaluation of 7-O-(. beta.-D-glucosaminyl) daunomycinone and 7-O-(. beta.-D-glucosaminyl) adriamycinone and their N-trifluoroacetyl derivatives
CS198280B2 (en) Method of producing anthracycline glycosides
CS236682B2 (en) Manufacturing process of 3-deamine analogs of glycoside antheracyclic antibiotics
HU196821B (en) Process for producing 6-deoxy-antracyclin-glycoside derivatives
US5045534A (en) 4-demethoxy-4'-amino-4'-deoxy-anthracycline derivatives
US4870058A (en) 14-Acyloxy-2'-halo-anthracycline anti-cancer antibiotics
Suarato Antitumour anthracyclines
US6258786B1 (en) 13-dihydro-3′ aziridino anthracyclines
GB2106900A (en) Anthracycline glycosides
FI70414C (fi) Foerfarande foer framstaellning av nya 4'-jodderivater av antracyklinglykosider
FI79715B (fi) Analogifoerfarande foer framstaellning av antracyklinglykosider.
US4604381A (en) 4-demethoxy-13-dihydrodaunorubicin and use thereof
FI89496B (fi) Foerfarande foer framstaellning av 4-demetoxi-4-aminoantracykliner
GB2034707A (en) Anthracycline glycosides
JPH03193798A (ja) アンスラサイクリン類、その製法及びそれを含有する医薬
SI8210860A8 (sl) Postopek za pripravo 4’-jodo derivatov antraciklinskih glikozidov
JPS6260397B2 (enExample)