ES8400120A1 - "un procedimiento para preparar un glicosido de antraciclina". - Google Patents
"un procedimiento para preparar un glicosido de antraciclina".Info
- Publication number
- ES8400120A1 ES8400120A1 ES515690A ES515690A ES8400120A1 ES 8400120 A1 ES8400120 A1 ES 8400120A1 ES 515690 A ES515690 A ES 515690A ES 515690 A ES515690 A ES 515690A ES 8400120 A1 ES8400120 A1 ES 8400120A1
- Authority
- ES
- Spain
- Prior art keywords
- doxorubicin
- glycoside
- image
- analogues
- anthracycline antibiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
UN PROCEDIMIENTO PARA PREPARAR UN GLICOSIDO DE ANTRACICLINA.SE HACE REACCIONAR SEPARADAMENTE A 0JC Y POR TRES O CUATRO HORAS CON NITRITO SODICO Y ACIDO ACETICO ACUOSO 1N, UNA SOLUCION ACUOSA DEL CLORHIDRATO CONOCIDO DE 3K, 4K-DIEPI-DAUNORRUBICINA O DE 3K,4K-DIEPI-DOXORRUBI CINA. SE OBTIENE UNA MEZCLA DESAMINADA DEL GLICOSIDO(I) (R1 F H; R2 F II; R3 F III) O BIEN DEL GLICOSIDO (I) EN QUE R1 F OH; R2 F II Y III; LA MEZCLA SE SEPARA POR CROMATOGRAFIA EN COLUMNA DE GEL DE SILICE, ELUYENDO PRIMERO CON CLOROFORMO Y LUEGO CON UNA MEZCLA DE CLOROFORMO Y ACETONA 97:3 (VOLUMEN/VOLUMEN).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8128252 | 1981-09-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES515690A0 ES515690A0 (es) | 1983-10-16 |
| ES8400120A1 true ES8400120A1 (es) | 1983-10-16 |
Family
ID=10524593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515690A Expired ES8400120A1 (es) | 1981-09-18 | 1982-09-14 | "un procedimiento para preparar un glicosido de antraciclina". |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS5862184A (es) |
| KR (1) | KR880001573B1 (es) |
| AU (1) | AU549656B2 (es) |
| BE (1) | BE894418A (es) |
| CA (1) | CA1184903A (es) |
| CH (1) | CH654014A5 (es) |
| CS (1) | CS236682B2 (es) |
| DE (1) | DE3233898A1 (es) |
| DK (1) | DK157030C (es) |
| ES (1) | ES8400120A1 (es) |
| FI (1) | FI823169L (es) |
| FR (1) | FR2513255A1 (es) |
| GR (1) | GR77639B (es) |
| HU (1) | HU186971B (es) |
| IE (1) | IE53330B1 (es) |
| IL (1) | IL66775A (es) |
| IT (1) | IT1210481B (es) |
| NL (1) | NL8203548A (es) |
| NO (1) | NO153335C (es) |
| NZ (1) | NZ201899A (es) |
| PT (1) | PT75575B (es) |
| SE (1) | SE456587B (es) |
| YU (1) | YU204982A (es) |
| ZA (1) | ZA826806B (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1506200A (en) * | 1975-04-30 | 1978-04-05 | Farmaceutici Italia | Glycosides |
-
1982
- 1982-09-13 IL IL66775A patent/IL66775A/xx unknown
- 1982-09-13 DE DE19823233898 patent/DE3233898A1/de active Granted
- 1982-09-13 YU YU02049/82A patent/YU204982A/xx unknown
- 1982-09-13 NL NL8203548A patent/NL8203548A/nl not_active Application Discontinuation
- 1982-09-13 AU AU88323/82A patent/AU549656B2/en not_active Ceased
- 1982-09-13 NZ NZ201899A patent/NZ201899A/en unknown
- 1982-09-14 CA CA000411403A patent/CA1184903A/en not_active Expired
- 1982-09-14 FI FI823169A patent/FI823169L/fi not_active Application Discontinuation
- 1982-09-14 FR FR8215507A patent/FR2513255A1/fr active Granted
- 1982-09-14 ES ES515690A patent/ES8400120A1/es not_active Expired
- 1982-09-14 IT IT8223240A patent/IT1210481B/it active
- 1982-09-15 IE IE2246/82A patent/IE53330B1/en unknown
- 1982-09-15 CS CS826643A patent/CS236682B2/cs unknown
- 1982-09-15 DK DK411382A patent/DK157030C/da not_active IP Right Cessation
- 1982-09-15 CH CH5463/82A patent/CH654014A5/it not_active IP Right Cessation
- 1982-09-15 SE SE8205288A patent/SE456587B/sv not_active IP Right Cessation
- 1982-09-16 ZA ZA826806A patent/ZA826806B/xx unknown
- 1982-09-16 JP JP57159743A patent/JPS5862184A/ja active Granted
- 1982-09-16 BE BE0/209035A patent/BE894418A/fr not_active IP Right Cessation
- 1982-09-16 NO NO823148A patent/NO153335C/no unknown
- 1982-09-17 GR GR69302A patent/GR77639B/el unknown
- 1982-09-17 PT PT75575A patent/PT75575B/pt unknown
- 1982-09-17 KR KR8204213A patent/KR880001573B1/ko active
- 1982-09-17 HU HU822977A patent/HU186971B/hu not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20001009 |