FR2491761A1 - Derives de l'adenosine a activite anti-inflammatoire et analgesique et compositions therapeutiques qui les contiennent en tant que principe actif - Google Patents

Derives de l'adenosine a activite anti-inflammatoire et analgesique et compositions therapeutiques qui les contiennent en tant que principe actif Download PDF

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Publication number
FR2491761A1
FR2491761A1 FR8107992A FR8107992A FR2491761A1 FR 2491761 A1 FR2491761 A1 FR 2491761A1 FR 8107992 A FR8107992 A FR 8107992A FR 8107992 A FR8107992 A FR 8107992A FR 2491761 A1 FR2491761 A1 FR 2491761A1
Authority
FR
France
Prior art keywords
mta
inflammatory
compounds
formula
acyl radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8107992A
Other languages
English (en)
French (fr)
Other versions
FR2491761B1 (enrdf_load_stackoverflow
Inventor
Giorgio Stramentinoli
Federico Gennari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioresearch SRL
Original Assignee
Bioresearch SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch SRL filed Critical Bioresearch SRL
Publication of FR2491761A1 publication Critical patent/FR2491761A1/fr
Application granted granted Critical
Publication of FR2491761B1 publication Critical patent/FR2491761B1/fr
Granted legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8107992A 1980-04-22 1981-04-22 Derives de l'adenosine a activite anti-inflammatoire et analgesique et compositions therapeutiques qui les contiennent en tant que principe actif Granted FR2491761A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (it) 1980-04-22 1980-04-22 Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo

Publications (2)

Publication Number Publication Date
FR2491761A1 true FR2491761A1 (fr) 1982-04-16
FR2491761B1 FR2491761B1 (enrdf_load_stackoverflow) 1984-01-06

Family

ID=11183457

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8107992A Granted FR2491761A1 (fr) 1980-04-22 1981-04-22 Derives de l'adenosine a activite anti-inflammatoire et analgesique et compositions therapeutiques qui les contiennent en tant que principe actif

Country Status (17)

Country Link
JP (2) JPS56166117A (enrdf_load_stackoverflow)
AR (1) AR231144A1 (enrdf_load_stackoverflow)
BE (1) BE888472A (enrdf_load_stackoverflow)
CA (1) CA1198105A (enrdf_load_stackoverflow)
CH (2) CH650514A5 (enrdf_load_stackoverflow)
DE (1) DE3116067A1 (enrdf_load_stackoverflow)
DK (1) DK159453C (enrdf_load_stackoverflow)
ES (2) ES501539A0 (enrdf_load_stackoverflow)
FI (1) FI70227C (enrdf_load_stackoverflow)
FR (1) FR2491761A1 (enrdf_load_stackoverflow)
GB (3) GB2074446B (enrdf_load_stackoverflow)
IT (1) IT1193529B (enrdf_load_stackoverflow)
LU (1) LU83307A1 (enrdf_load_stackoverflow)
MX (1) MX9203630A (enrdf_load_stackoverflow)
NL (1) NL192111C (enrdf_load_stackoverflow)
NO (1) NO150515C (enrdf_load_stackoverflow)
SE (3) SE460198B (enrdf_load_stackoverflow)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177373B (it) * 1984-12-06 1987-08-26 Bioresearch Spa Sali della 5'-metiltio-5'-deossiadenosina con acidi solfonici a lunga catena alchilica
IT1227049B (it) * 1988-07-29 1991-03-14 Bioresearch Spa Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.
JPH0497287A (ja) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd 画像表示集積回路
WO2006097547A1 (es) * 2005-03-17 2006-09-21 Proyecto De Biomedicina Cima S.L. Empleo de 5'-metiltioadenosina (mta) en la prevención y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes
ES2259552B1 (es) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes.
DE102010027595A1 (de) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Vermeidung von Ischämie- oder Degenerations-Schäden im Gehirn bei Anwendung von Adenosin-Derivaten
DE102011005232A1 (de) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosin und seine Derivate zur Verwendung in der Schmerztherapie
WO2014163152A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 ノンレム睡眠促進剤、深睡眠促進剤および自然睡眠誘発剤
KR102245628B1 (ko) * 2013-04-05 2021-04-28 라이온 가부시키가이샤 내복 조성물
CN105102609B (zh) * 2013-04-05 2018-07-20 狮王株式会社 酵母培养物和内服组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1259341B (de) * 1962-12-22 1968-01-25 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 5'-Sulfoxyde von Nucleosiden
DE1545645A1 (de) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Verfahren zur Herstellung von disubstituierten Adenosin-Derivaten
GB1436509A (en) * 1973-11-27 1976-05-19 Ajinomoto Kk Method for producing s-adenosylmethionine or methylthioadenosine from yeast
FR2313937A1 (fr) * 1975-06-09 1977-01-07 Anvar Medicament a base de 5' thioethers de l'adenosine
FR2424027A1 (fr) * 1978-04-28 1979-11-23 Merieux Inst Nouveau medicament, notamment sedatif et inducteur de sommeil et compositions pharmaceutiques la renfermant

Also Published As

Publication number Publication date
ES511039A0 (es) 1983-06-01
NO150515B (no) 1984-07-23
GB2074446A (en) 1981-11-04
FI70227B (fi) 1986-02-28
DE3116067A1 (de) 1982-03-11
NL192111B (nl) 1996-10-01
GB8413454D0 (en) 1984-07-04
GB2144038A (en) 1985-02-27
CH650514A5 (de) 1985-07-31
FI70227C (fi) 1986-09-15
SE8700913L (sv) 1987-03-04
SE464635B (sv) 1991-05-27
BE888472A (fr) 1981-08-17
JPS56166117A (en) 1981-12-21
SE8102489L (sv) 1981-10-23
NO811346L (no) 1981-10-23
AR231144A1 (es) 1984-09-28
FI811249L (fi) 1981-10-23
SE8700913D0 (sv) 1987-03-04
LU83307A1 (fr) 1981-07-24
SE8700914D0 (sv) 1987-03-04
IT8021550A0 (it) 1980-04-22
SE8700914L (sv) 1987-03-04
SE466238B (sv) 1992-01-20
DE3116067C2 (enrdf_load_stackoverflow) 1992-12-17
DK159453C (da) 1991-03-18
NO150515C (no) 1984-10-31
NL192111C (nl) 1997-02-04
DK176481A (da) 1981-10-23
CA1198105A (en) 1985-12-17
SE460198B (sv) 1989-09-18
FR2491761B1 (enrdf_load_stackoverflow) 1984-01-06
GB2144038B (en) 1985-08-29
ES8206551A1 (es) 1982-08-16
JPH01301692A (ja) 1989-12-05
GB2144409A (en) 1985-03-06
NL8101984A (nl) 1981-11-16
ES501539A0 (es) 1982-08-16
IT1193529B (it) 1988-07-08
MX9203630A (es) 1992-09-01
DK159453B (da) 1990-10-15
GB2074446B (en) 1985-04-11
ES8306378A1 (es) 1983-06-01
GB8321947D0 (en) 1983-09-14
CH645544A5 (de) 1984-10-15
GB2144409B (en) 1985-09-11
JPH0249288B2 (enrdf_load_stackoverflow) 1990-10-29
JPH0246599B2 (enrdf_load_stackoverflow) 1990-10-16

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