FR2398049A1 - Nouveaux analogues de l'angiotensine ii et procede permettant de les preparer - Google Patents

Nouveaux analogues de l'angiotensine ii et procede permettant de les preparer

Info

Publication number
FR2398049A1
FR2398049A1 FR7821045A FR7821045A FR2398049A1 FR 2398049 A1 FR2398049 A1 FR 2398049A1 FR 7821045 A FR7821045 A FR 7821045A FR 7821045 A FR7821045 A FR 7821045A FR 2398049 A1 FR2398049 A1 FR 2398049A1
Authority
FR
France
Prior art keywords
angiotensin
preparing
new analogues
analogues
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7821045A
Other languages
English (en)
Other versions
FR2398049B1 (fr
Inventor
Lajos Kisfaludy
Gyorgy Nieki
Laszlo Szirmai
Egon Karpati
Katalin Gidai
Laszlo Szporny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of FR2398049A1 publication Critical patent/FR2398049A1/fr
Application granted granted Critical
Publication of FR2398049B1 publication Critical patent/FR2398049B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés chimiques nouveaux. Il s'agit de peptides de formule générale :
FR7821045A 1977-07-18 1978-07-13 Nouveaux analogues de l'angiotensine ii et procede permettant de les preparer Granted FR2398049A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77RI641A HU177134B (en) 1977-07-18 1977-07-18 Process for preparing angiotensin ii analogues containing alpha-hydroxy-acid in position 1 with angiotensin ii antagonist activity

Publications (2)

Publication Number Publication Date
FR2398049A1 true FR2398049A1 (fr) 1979-02-16
FR2398049B1 FR2398049B1 (fr) 1984-06-08

Family

ID=11001038

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7821045A Granted FR2398049A1 (fr) 1977-07-18 1978-07-13 Nouveaux analogues de l'angiotensine ii et procede permettant de les preparer

Country Status (24)

Country Link
US (1) US4209442A (fr)
JP (1) JPS5831337B2 (fr)
AT (1) AT360678B (fr)
AU (1) AU520176B2 (fr)
BE (1) BE869076A (fr)
CA (1) CA1114810A (fr)
CH (1) CH637916A5 (fr)
CS (1) CS201013B2 (fr)
DD (1) DD137221A5 (fr)
DE (1) DE2831271C2 (fr)
DK (1) DK319578A (fr)
ES (1) ES471791A1 (fr)
FI (1) FI64797C (fr)
FR (1) FR2398049A1 (fr)
GB (1) GB2002779B (fr)
HU (1) HU177134B (fr)
IL (1) IL55075A (fr)
IN (1) IN149852B (fr)
NL (1) NL7807627A (fr)
NO (1) NO148070C (fr)
PL (1) PL111964B1 (fr)
SE (1) SE444439B (fr)
SU (1) SU913940A3 (fr)
YU (1) YU41315B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2546163A1 (fr) * 1983-05-16 1984-11-23 Centre Nat Rech Scient Nouveaux derives acyles hydrosolubles de peptides ou d'amino-acides, leur preparation et leur application

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905502C2 (de) * 1979-02-14 1982-07-15 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von LH-RH bzw. LH-RH-Analoga und Pyroglutamyl-N↑i↑m↑-dinitrophenyl-histidin
HU181009B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for preparing angiotensin-ii analogues with antagonictic activity containing in position 1 sarcosyl,hydroxyacetyl or l-alpha-aminoxy-propionyl group and in positiona 8 esteric group
HU181008B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position
JPS60132197A (ja) * 1983-12-02 1985-07-15 日東電工株式会社 管の接合方法
HU191961B (en) * 1984-08-02 1987-04-28 Richter Gedeon Vegyeszet Process for producing 1,5 and 8 substituted peptides of angiotenzin-ii antagonistic activity
US5182264A (en) * 1986-03-07 1993-01-26 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
US4772684A (en) * 1987-01-20 1988-09-20 Triton Biosciences, Inc. Peptides affecting blood pressure regulation
JPH053629Y2 (fr) * 1987-10-09 1993-01-28
DK1385870T3 (da) * 2000-07-21 2010-07-05 Schering Corp Peptider som inhibitorer af NS3-serinprotease fra hepatitis C-virus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1320104A (en) * 1971-05-20 1973-06-13 Norwich Pharma Co Hepta-and octapeptides
US3907762A (en) * 1971-12-27 1975-09-23 Univ Sherbrooke Angiotensin{hd II {B position 8 analogs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886134A (en) * 1970-03-09 1975-05-27 Morton Norwich Products Inc Analogues of angiotensin II
DE2323322A1 (de) * 1973-05-09 1974-11-28 Hoechst Ag Neue peptide mit blutdrucksenkender wirkung und verfahren zu ihrer herstellung
US3923771A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus N-Guanidylacetyl-{8 des-asp{hu 1{b -Ile{hu 8{b {9 {0 angiotensin II as an angiotensin antagonist

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1320104A (en) * 1971-05-20 1973-06-13 Norwich Pharma Co Hepta-and octapeptides
US3907762A (en) * 1971-12-27 1975-09-23 Univ Sherbrooke Angiotensin{hd II {B position 8 analogs

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EXBK/62 *
HW1974 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2546163A1 (fr) * 1983-05-16 1984-11-23 Centre Nat Rech Scient Nouveaux derives acyles hydrosolubles de peptides ou d'amino-acides, leur preparation et leur application
EP0126685A1 (fr) * 1983-05-16 1984-11-28 Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) Nouveaux dérivés acylés hydrosolubles de peptides ou d'amino-acides, leur préparation et leur application

Also Published As

Publication number Publication date
NL7807627A (nl) 1979-01-22
ES471791A1 (es) 1979-02-01
CA1114810A (fr) 1981-12-22
YU171578A (en) 1982-10-31
CS201013B2 (en) 1980-10-31
GB2002779A (en) 1979-02-28
SE7807824L (sv) 1979-01-19
IL55075A0 (en) 1978-09-29
GB2002779B (en) 1982-01-27
IL55075A (en) 1981-12-31
HU177134B (en) 1981-07-28
SE444439B (sv) 1986-04-14
DK319578A (da) 1979-01-19
DD137221A5 (de) 1979-08-22
PL111964B1 (en) 1980-09-30
JPS5831337B2 (ja) 1983-07-05
DE2831271A1 (de) 1979-03-01
BE869076A (fr) 1979-01-18
NO148070B (no) 1983-04-25
NO148070C (no) 1983-08-03
SU913940A3 (en) 1982-03-15
ATA518378A (de) 1980-06-15
IN149852B (fr) 1982-05-08
CH637916A5 (de) 1983-08-31
DE2831271C2 (de) 1982-02-25
AU3800978A (en) 1980-01-17
AU520176B2 (en) 1982-01-21
FI64797B (fi) 1983-09-30
PL208497A1 (pl) 1979-07-02
AT360678B (de) 1979-04-15
FI782216A (fi) 1979-01-19
YU41315B (en) 1987-02-28
FR2398049B1 (fr) 1984-06-08
JPS5422368A (en) 1979-02-20
US4209442A (en) 1980-06-24
NO782464L (no) 1979-01-19
FI64797C (fi) 1984-01-10

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Legal Events

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ST Notification of lapse