FR2398050A1 - Nouveaux analogues antagonistes de l'angiotensine ii contenant un oxacide a-amine en position 1 - Google Patents

Nouveaux analogues antagonistes de l'angiotensine ii contenant un oxacide a-amine en position 1

Info

Publication number
FR2398050A1
FR2398050A1 FR7821136A FR7821136A FR2398050A1 FR 2398050 A1 FR2398050 A1 FR 2398050A1 FR 7821136 A FR7821136 A FR 7821136A FR 7821136 A FR7821136 A FR 7821136A FR 2398050 A1 FR2398050 A1 FR 2398050A1
Authority
FR
France
Prior art keywords
oxacid
angiotensin
amine
antagonist analogues
new antagonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7821136A
Other languages
English (en)
Other versions
FR2398050B1 (fr
Inventor
Lajos Kisfaludy
Gyorgy Nyeki
Laszlo Szirmai
Egon Karpati
Katalin Gidai
Laszlo Szporny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of FR2398050A1 publication Critical patent/FR2398050A1/fr
Application granted granted Critical
Publication of FR2398050B1 publication Critical patent/FR2398050B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne des composés chimiques nouveaux. Il s'agit de peptides de formule générale :
FR7821136A 1977-07-18 1978-07-17 Nouveaux analogues antagonistes de l'angiotensine ii contenant un oxacide a-amine en position 1 Granted FR2398050A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77RI640A HU177133B (en) 1977-07-18 1977-07-18 Process for preparing angiotensin ii analogues containing alpha- amino-oxy-acid in position 1 with angiotensin ii antagonist activity

Publications (2)

Publication Number Publication Date
FR2398050A1 true FR2398050A1 (fr) 1979-02-16
FR2398050B1 FR2398050B1 (fr) 1983-09-09

Family

ID=11001037

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7821136A Granted FR2398050A1 (fr) 1977-07-18 1978-07-17 Nouveaux analogues antagonistes de l'angiotensine ii contenant un oxacide a-amine en position 1

Country Status (24)

Country Link
US (1) US4179433A (fr)
JP (1) JPS5835504B2 (fr)
AT (1) AT361143B (fr)
AU (1) AU518229B2 (fr)
BE (1) BE869077A (fr)
CA (1) CA1108124A (fr)
CH (1) CH637915A5 (fr)
CS (1) CS201014B2 (fr)
DD (1) DD137220A5 (fr)
DE (1) DE2831534C2 (fr)
DK (1) DK319478A (fr)
ES (1) ES471793A1 (fr)
FI (1) FI64140C (fr)
FR (1) FR2398050A1 (fr)
GB (1) GB2001653B (fr)
HU (1) HU177133B (fr)
IL (1) IL55121A (fr)
IN (1) IN149489B (fr)
NL (1) NL7807676A (fr)
NO (1) NO148031C (fr)
PL (1) PL111979B1 (fr)
SE (1) SE443790B (fr)
SU (1) SU845773A3 (fr)
YU (1) YU41431B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181009B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for preparing angiotensin-ii analogues with antagonictic activity containing in position 1 sarcosyl,hydroxyacetyl or l-alpha-aminoxy-propionyl group and in positiona 8 esteric group
HU181008B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position
HU191961B (en) * 1984-08-02 1987-04-28 Richter Gedeon Vegyeszet Process for producing 1,5 and 8 substituted peptides of angiotenzin-ii antagonistic activity
US5036048A (en) * 1986-03-07 1991-07-30 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
US5182264A (en) * 1986-03-07 1993-01-26 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
US4772684A (en) * 1987-01-20 1988-09-20 Triton Biosciences, Inc. Peptides affecting blood pressure regulation
TWI268138B (en) * 2000-05-11 2006-12-11 Kanebo Seiyaku Ltd Composition containing peptide and electrolyte excretion enhancing substance, and food containing the same
AT508569A1 (de) 2009-07-23 2011-02-15 Affiris Ag Pharmaceutical compound

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1320104A (en) * 1971-05-20 1973-06-13 Norwich Pharma Co Hepta-and octapeptides
US3907762A (en) * 1971-12-27 1975-09-23 Univ Sherbrooke Angiotensin{hd II {B position 8 analogs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886134A (en) * 1970-03-09 1975-05-27 Morton Norwich Products Inc Analogues of angiotensin II
HU167360B (fr) * 1972-08-25 1975-09-27
US3975365A (en) * 1975-01-27 1976-08-17 G. D. Searle & Co. Inhibitory octapeptides angiotensin II
US3976770A (en) * 1975-02-10 1976-08-24 Francis Merlin Bumpus Sar'-(OMe)Thr8 Angiotensin II as an angiotensin II antagonist

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1320104A (en) * 1971-05-20 1973-06-13 Norwich Pharma Co Hepta-and octapeptides
US3907762A (en) * 1971-12-27 1975-09-23 Univ Sherbrooke Angiotensin{hd II {B position 8 analogs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/72 *

Also Published As

Publication number Publication date
YU171378A (en) 1983-01-21
PL111979B1 (en) 1980-09-30
FR2398050B1 (fr) 1983-09-09
ATA518478A (de) 1980-07-15
DD137220A5 (de) 1979-08-22
IL55121A0 (en) 1978-09-29
US4179433A (en) 1979-12-18
IN149489B (fr) 1981-12-26
JPS54119463A (en) 1979-09-17
SE443790B (sv) 1986-03-10
GB2001653A (en) 1979-02-07
DK319478A (da) 1979-01-19
JPS5835504B2 (ja) 1983-08-03
HU177133B (en) 1981-07-28
DE2831534C2 (de) 1982-02-18
CA1108124A (fr) 1981-09-01
SE7807823L (sv) 1979-01-19
NO148031C (no) 1983-07-27
NL7807676A (nl) 1979-01-22
FI64140C (fi) 1983-10-10
FI64140B (fi) 1983-06-30
CS201014B2 (en) 1980-10-31
YU41431B (en) 1987-06-30
IL55121A (en) 1981-09-13
SU845773A3 (ru) 1981-07-07
GB2001653B (en) 1982-02-10
ES471793A1 (es) 1979-02-01
NO782463L (no) 1979-01-19
PL208496A1 (pl) 1979-07-02
AU518229B2 (en) 1981-09-17
DE2831534A1 (de) 1979-02-01
CH637915A5 (de) 1983-08-31
AU3800878A (en) 1980-01-17
BE869077A (fr) 1979-01-18
AT361143B (de) 1981-02-25
NO148031B (no) 1983-04-18
FI782250A (fi) 1979-01-19

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Legal Events

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ST Notification of lapse