FR2381763A1 - Dibenzo(b-e) (diazepines-1,4) et leur utilisation comme antischizophreniques - Google Patents

Dibenzo(b-e) (diazepines-1,4) et leur utilisation comme antischizophreniques

Info

Publication number
FR2381763A1
FR2381763A1 FR7805101A FR7805101A FR2381763A1 FR 2381763 A1 FR2381763 A1 FR 2381763A1 FR 7805101 A FR7805101 A FR 7805101A FR 7805101 A FR7805101 A FR 7805101A FR 2381763 A1 FR2381763 A1 FR 2381763A1
Authority
FR
France
Prior art keywords
antischizophrenics
diazepines
dibenzo
õdiazepines
dibenzoøb
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7805101A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of FR2381763A1 publication Critical patent/FR2381763A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

L'invention concerne des dibenzoØb-eõ Ødiazépines-1,4õ utiles comme médicaments. Les composés de l'invention ont pour formule :
FR7805101A 1977-02-23 1978-02-22 Dibenzo(b-e) (diazepines-1,4) et leur utilisation comme antischizophreniques Withdrawn FR2381763A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/771,216 US4097597A (en) 1977-02-23 1977-02-23 Dibenzo b,e! 1,4!diazepines

Publications (1)

Publication Number Publication Date
FR2381763A1 true FR2381763A1 (fr) 1978-09-22

Family

ID=25091087

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7805101A Withdrawn FR2381763A1 (fr) 1977-02-23 1978-02-22 Dibenzo(b-e) (diazepines-1,4) et leur utilisation comme antischizophreniques

Country Status (5)

Country Link
US (1) US4097597A (fr)
JP (1) JPS53105489A (fr)
DE (1) DE2807568A1 (fr)
FR (1) FR2381763A1 (fr)
GB (1) GB1562874A (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404137A (en) * 1979-10-16 1983-09-13 Lilly Industries Limited Pyrazolo [3,4-b][1,5]benzodiazepine compounds
EP0031115A1 (fr) * 1979-12-21 1981-07-01 Sandoz Ag Pyrrolobenzotriazépines, leur préparation et compositions pharmaceutiques les contenant
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
US5994392A (en) 1988-02-26 1999-11-30 Neuromedica, Inc. Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid
US5602121A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. Alkyl-substituted compounds having dopamine receptor affinity
US5700445A (en) * 1994-12-12 1997-12-23 Allelix Biopharmaceuticals, Inc. N-methyl piperazine compounds having dopamine receptor affinity
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6576636B2 (en) * 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US5955459A (en) * 1997-11-26 1999-09-21 Neuromedica, Inc. Fatty acid-antipsychotic compositions and uses thereof
US6197764B1 (en) * 1997-11-26 2001-03-06 Protarga, Inc. Clozapine compositions and uses thereof
US6225444B1 (en) 1998-02-10 2001-05-01 Protarga, Inc. Neuroprotective peptides and uses thereof
US7235583B1 (en) * 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
ES2387562T3 (es) * 2001-03-23 2012-09-26 Luitpold Pharmaceuticals, Inc. Conjugados alcohol graso-medicamento
EP1427407A4 (fr) * 2001-03-23 2005-05-11 Luitpold Pharm Inc Conjugues a base d'amines gras et d'agents pharmaceutiques
JP3977162B2 (ja) * 2002-06-21 2007-09-19 株式会社バンダイナムコゲームス キャラクタ情報管理装置、プログラム及び情報記憶媒体
US20050085463A1 (en) * 2003-01-23 2005-04-21 Weiner David M. Use of N-desmethylclozapine to treat human neuropsychiatric disease
US20050250767A1 (en) * 2003-01-23 2005-11-10 Weiner David M Use of N-desmethylclozapine to treat human neuropsychiatric disease
BRPI0406592A (pt) * 2003-01-23 2005-12-20 Acadia Pharm Inc Usos de n-desmetilclozapina, métodos para o tratamento de psicose, de distúrbios afetivos, de demência, de dor neuropática e de glaucoma e composição farmacêutica
PT1696931E (pt) * 2003-12-22 2009-06-12 Acadia Pharm Inc Análogos diaril[a,d]ciclo-hepteno substituídos com amino utilizados como agonistas muscarínicos e métodos de tratamento de perturbações neuropsiquiátricas
CN1913900B (zh) * 2003-12-22 2010-11-24 阿卡蒂亚药品公司 作为毒蕈碱激动剂的氨基取代的二芳基[a，d]环庚烯类似物及神经精神疾病的治疗方法
BRPI0509524A (pt) * 2004-04-01 2007-09-18 Acadia Pharm Inc formas cristalinas de n-desmetilclozapina
WO2007053618A1 (fr) * 2005-10-31 2007-05-10 Acadia Pharmaceuticals Inc. Promédicaments d'agonistes muscariniques et méthodes de traitement de troubles neuropsychiatriques
WO2008079839A1 (fr) * 2006-12-20 2008-07-03 Astrazeneca Ab Composés et utilisations de ceux-ci
US8389510B2 (en) * 2005-11-18 2013-03-05 Astrazeneca Ab Crystalline forms
KR101539797B1 (ko) * 2007-11-28 2015-07-27 넥타르 테라퓨틱스 올리고머-삼환계 콘쥬게이트
GB201910873D0 (en) 2019-07-30 2019-09-11 Zarodex Therapeutics Ltd Novel uses

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2222102A1 (en) * 1973-03-23 1974-10-18 Wander Ag Dr A 11-Piperazino dibenzo diazepines neuroleptics - and anti-depressants, prepd. from a dibenzo diazepin-11-one and a piperazine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3796725A (en) * 1971-01-27 1974-03-12 Squibb & Sons Inc N-oxides of 5-(aminoalkyl)-5,11-dihydro-dibenzoxazepines and 5,11-dihydrodi-benzthiazepines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2222102A1 (en) * 1973-03-23 1974-10-18 Wander Ag Dr A 11-Piperazino dibenzo diazepines neuroleptics - and anti-depressants, prepd. from a dibenzo diazepin-11-one and a piperazine

Also Published As

Publication number Publication date
JPS53105489A (en) 1978-09-13
GB1562874A (en) 1980-03-19
US4097597A (en) 1978-06-27
DE2807568A1 (de) 1978-08-31

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