FR2222102A1 - 11-Piperazino dibenzo diazepines neuroleptics - and anti-depressants, prepd. from a dibenzo diazepin-11-one and a piperazine - Google Patents

11-Piperazino dibenzo diazepines neuroleptics - and anti-depressants, prepd. from a dibenzo diazepin-11-one and a piperazine

Info

Publication number
FR2222102A1
FR2222102A1 FR7410147A FR7410147A FR2222102A1 FR 2222102 A1 FR2222102 A1 FR 2222102A1 FR 7410147 A FR7410147 A FR 7410147A FR 7410147 A FR7410147 A FR 7410147A FR 2222102 A1 FR2222102 A1 FR 2222102A1
Authority
FR
France
Prior art keywords
dibenzo
diazepines
neuroleptics
diazepin
piperazino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7410147A
Other languages
French (fr)
Other versions
FR2222102B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wander AG
Original Assignee
Wander AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wander AG filed Critical Wander AG
Publication of FR2222102A1 publication Critical patent/FR2222102A1/en
Application granted granted Critical
Publication of FR2222102B1 publication Critical patent/FR2222102B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Title cpds. of formula (I):- (where R1 = H, 1-4C alkyl, is not >5C alkoxyalkyl, or opt. acylated is not >4C hydroxyalkyl; R2 = H or 1-3C alkyl; R3-6 = H, halogen, NO2, CN, CF3, alkyl, alkoxy, alkylthio, alkylsulphonyl or disalkylsulphamoyl (alkyl's contng. 1-4C), >=2 of R3-6 are not H; R5 and R6 together may form -O(CH2)nO-; n = 1 or 2).
FR7410147A 1973-03-23 1974-03-25 11-Piperazino dibenzo diazepines neuroleptics - and anti-depressants, prepd. from a dibenzo diazepin-11-one and a piperazine Granted FR2222102A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH425973 1973-03-23
CH514773 1973-04-10
CH664473 1973-05-10

Publications (2)

Publication Number Publication Date
FR2222102A1 true FR2222102A1 (en) 1974-10-18
FR2222102B1 FR2222102B1 (en) 1978-01-06

Family

ID=27174779

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7410147A Granted FR2222102A1 (en) 1973-03-23 1974-03-25 11-Piperazino dibenzo diazepines neuroleptics - and anti-depressants, prepd. from a dibenzo diazepin-11-one and a piperazine

Country Status (7)

Country Link
JP (1) JPS49126691A (en)
AU (1) AU6704374A (en)
DD (1) DD110498A5 (en)
DE (1) DE2413610A1 (en)
FR (1) FR2222102A1 (en)
IL (1) IL44458A0 (en)
NL (1) NL7403657A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2381763A1 (en) * 1977-02-23 1978-09-22 Abbott Lab DIBENZO (B-E) (DIAZEPINES-1,4) AND THEIR USE AS AN ANTISCHIZOPHRENICS
EP0031115A1 (en) * 1979-12-21 1981-07-01 Sandoz Ag New pyrrolobenzotriazepines, their production and pharmaceutical compositions containing them
EP0054416A2 (en) * 1980-12-11 1982-06-23 Lilly Industries Limited Benzodiazepine compounds and their use as pharmaceuticals
BE1004596A4 (en) * 1990-09-26 1992-12-22 Therabel Res S A N V Methylpiperazinoazepine DERIVATIVES, PREPARATION AND USE.
US5393752A (en) * 1992-05-26 1995-02-28 Therabel Research S.A./N.V. Methylpiperazinoazepine compounds, preparation and use thereof
WO2005063254A2 (en) * 2003-12-22 2005-07-14 Acadia Pharmaceuticals Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
WO2008021463A2 (en) * 2006-08-15 2008-02-21 Acadia Pharmaceuticals, Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
EP3424506A4 (en) * 2016-03-04 2019-11-06 Obschestvo S Ogranichennoi Otvetstvennostyu Valentek Pharmaceutical composition for treating functional psychiatric disorders

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050106465A (en) * 2003-02-27 2005-11-09 아보트 러보러터리즈 Heterocyclic kinase inhibitors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
FR2179071A1 (en) * 1972-04-04 1973-11-16 Wander Ag Dr A

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
FR2179071A1 (en) * 1972-04-04 1973-11-16 Wander Ag Dr A

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2381763A1 (en) * 1977-02-23 1978-09-22 Abbott Lab DIBENZO (B-E) (DIAZEPINES-1,4) AND THEIR USE AS AN ANTISCHIZOPHRENICS
EP0031115A1 (en) * 1979-12-21 1981-07-01 Sandoz Ag New pyrrolobenzotriazepines, their production and pharmaceutical compositions containing them
EP0054416A2 (en) * 1980-12-11 1982-06-23 Lilly Industries Limited Benzodiazepine compounds and their use as pharmaceuticals
EP0054416A3 (en) * 1980-12-11 1982-09-08 Lilly Industries Limited Benzodiazepine compounds and their use as pharmaceuticals
BE1004596A4 (en) * 1990-09-26 1992-12-22 Therabel Res S A N V Methylpiperazinoazepine DERIVATIVES, PREPARATION AND USE.
US5393752A (en) * 1992-05-26 1995-02-28 Therabel Research S.A./N.V. Methylpiperazinoazepine compounds, preparation and use thereof
US7550454B2 (en) 2003-12-22 2009-06-23 Acadia Pharmaceuticals, Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
WO2005063254A3 (en) * 2003-12-22 2005-09-15 Acadia Pharm Inc Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
US7491715B2 (en) 2003-12-22 2009-02-17 Acadia Pharmaceuticals, Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
US7517871B2 (en) 2003-12-22 2009-04-14 Acadia Pharmaceuticals, Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
WO2005063254A2 (en) * 2003-12-22 2005-07-14 Acadia Pharmaceuticals Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
EP2088147A1 (en) * 2003-12-22 2009-08-12 Arcadia Pharmaceuticals Inc. Dibenzo-condensed azepine, diazepine, oxazepine and thiazepine derivatives as muscarinic agonists and methods of treatment of neuropsychiatric disorders
US7622461B2 (en) 2003-12-22 2009-11-24 Acadia Pharmaceuticals Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
AU2004308955B2 (en) * 2003-12-22 2011-08-04 Acadia Pharmaceuticals Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
WO2008021463A2 (en) * 2006-08-15 2008-02-21 Acadia Pharmaceuticals, Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
WO2008021463A3 (en) * 2006-08-15 2008-12-24 Acadia Pharm Inc Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
EP3424506A4 (en) * 2016-03-04 2019-11-06 Obschestvo S Ogranichennoi Otvetstvennostyu Valentek Pharmaceutical composition for treating functional psychiatric disorders

Also Published As

Publication number Publication date
NL7403657A (en) 1974-09-25
DE2413610A1 (en) 1974-10-10
IL44458A0 (en) 1974-06-30
AU6704374A (en) 1975-09-25
DD110498A5 (en) 1974-12-20
JPS49126691A (en) 1974-12-04
FR2222102B1 (en) 1978-01-06

Similar Documents

Publication Publication Date Title
FR2222102A1 (en) 11-Piperazino dibenzo diazepines neuroleptics - and anti-depressants, prepd. from a dibenzo diazepin-11-one and a piperazine
DE19475021I2 (en) Naphthoquinone derivatives
DE3585111D1 (en) SPIRO-OXAZINE COMPOUNDS, THEIR PRODUCTION AND PHOTOCHROMIC MOLDED ARTICLES.
DE3585980D1 (en) HYDRAZINE DERIVATIVES AND THEIR USE.
FR2110283A1 (en) 2-phenyl-as-triazine-3,4 (2h,4h)-dione derivs - having coccidiostatic activity
BE812742A (en) 11-Piperazino dibenzo diazepines neuroleptics - and anti-depressants, prepd. from a dibenzo diazepin-11-one and a piperazine
GB1421086A (en) Triazolobenzodiazepines preparation
JPS57163368A (en) 4-aryloxy-1,2,3,4-tetrahydroisoquinoline and intermediate
MY102440A (en) Fungicidal pyridyl cyclopropane carboxamides.
GB2247237B (en) 1-(N'-Cyanoguanyl) derivatives of N-containing five-membered ring heterocycles
ES431804A1 (en) Acylated 2-aminothiazole derivatives
DE69219748D1 (en) Siloxane compounds, their production and use
ATE15894T1 (en) HETEROCYCLIC DERIVATIVES OF AMIDOXINS, THEIR PRODUCTION AND THERAPEUTIC USE.
IE39965L (en) Imidazotriazines
FR2166101A1 (en) 1,4-di (morpholino,piperidino or pyrrolidino)-7-substd - -pyrido (3,4-d)-pyridazines - as diuretics
FI822407A0 (en) PROCEDURE FOR FRAMSTATION OF 6- / 3,6-DIHYDRO-1 (2H) -PYRIDYL / PYRIMIDIN-3-OXIDER
ES464068A1 (en) Quinolone derivatives
FR2224137A2 (en) 3-(Alkyn-3-yloxy)-1-piperazinopropan-2-ols - with neuroleptic, antihypertensive, antiemetic and antitussive activity
BE803210A (en) Corynanthine hydrazides - as therapeutic agents
SE8600742L (en) TREATMENT
FR2140347A1 (en) 2-cinnamoyl-1-(2-hydroxyethyl) benzimidazoles - with vasodilator , hypotensive respiratory analeptic, diuretic and analgesic activity
ZA826753B (en) 4-(2-fluoro-4-halo-5-substituted phenyl)-urazols,and their production and use
FR2198736A1 (en) 4-(Carboxy thienyl) quinolines - with antiinflammatory and analgesic activity
SU1160709A1 (en) HYDROCHLORIDE 6-METHYL-1-OXO-1,2,3,4-TETRAHYDROINDOLO / 2,3-C / -CHINOLINA, possessing a tranquilizing activity
BE807978A (en) Carbostyryl-oxymethyl-oxazolidines - useful as beta-adrenergic agents

Legal Events

Date Code Title Description
ST Notification of lapse