FR2110283A1 - 2-phenyl-as-triazine-3,4 (2h,4h)-dione derivs - having coccidiostatic activity - Google Patents
2-phenyl-as-triazine-3,4 (2h,4h)-dione derivs - having coccidiostatic activityInfo
- Publication number
- FR2110283A1 FR2110283A1 FR7136162A FR7136162A FR2110283A1 FR 2110283 A1 FR2110283 A1 FR 2110283A1 FR 7136162 A FR7136162 A FR 7136162A FR 7136162 A FR7136162 A FR 7136162A FR 2110283 A1 FR2110283 A1 FR 2110283A1
- Authority
- FR
- France
- Prior art keywords
- phenyl
- heterocyclic
- chosen
- atom form
- triazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Abstract
Novel title cpds. have formula: (where R2, R6 = H, F, Cl, CN, CH3 at least one being H or F, R3, R4, R5 = (a) H, halo, CN, CF3, lower alkyl (b) lower alkoxy, lower alkylthio (c) -NO2, -SCN with the condition that when at least one of R3 and R5 is chosen from (b) R4 chosen from (a) other than H or (c) and no more than two of R2, R3, R4, R5, R6 are H or R3 and R5 are chosen from (a), (b) and (c) R4 = -NR7R8, lower alkanoyl, alkylsulphonyl, -SO2-NRR1, with the condition that when R4 = SO2NRR1 or alkanoyl at least one of R3 and R5 is not = H, R = methl, ethyl, phenyl, benzyl, allyl, propargyl, p-chlorophenyl R1 = methyl, ethyl, allyl, propargyl or R and R1 together with the N atom form a heterocyclic R and R1 together with the N atom form a heterocyclic gp. W, R7 R8 = 1-4C alkyl or R7 and R8 together with the N atom form a heterocyclic gp. W, W = morpholino, theomorpholinc, pyrrolo, pyrrolino, pyrrolidino, piperidino, N-(lower alkyl)-piperazino, hexamethyleneimino, thiazolidino, DELTA 3-tetrahydropyridino or piperazino, X = O, S, NH, SO, SO2, -CHOH, CO, Y, Y1 = H, halo, NO2 CN, lower alkyl or loweralkoxy) and also their alkali(ne earth) metal salts.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7891770A | 1970-10-07 | 1970-10-07 | |
US12913971A | 1971-03-29 | 1971-03-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2110283A1 true FR2110283A1 (en) | 1972-06-02 |
FR2110283B1 FR2110283B1 (en) | 1975-10-31 |
Family
ID=26761102
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7136162A Granted FR2110283A1 (en) | 1970-10-07 | 1971-10-07 | 2-phenyl-as-triazine-3,4 (2h,4h)-dione derivs - having coccidiostatic activity |
Country Status (12)
Country | Link |
---|---|
AR (2) | AR195271A1 (en) |
BE (1) | BE773583A (en) |
BR (1) | BR7106641D0 (en) |
CA (1) | CA992538A (en) |
CH (2) | CH566328A5 (en) |
DE (1) | DE2149645A1 (en) |
ES (1) | ES395778A1 (en) |
FR (1) | FR2110283A1 (en) |
HU (1) | HU166467B (en) |
IL (1) | IL37861A0 (en) |
IT (1) | IT1050658B (en) |
NL (1) | NL7113797A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0331232A3 (en) * | 1988-02-29 | 1991-04-24 | Janssen Pharmaceutica N.V. | 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols |
WO2001005793A1 (en) * | 1999-07-19 | 2001-01-25 | Pharmacia & Upjohn Company | 1,2,3,4,5,6-HEXAHYDROAZEPINO[4,5-b]INDOLES CONTAINING ARYLSULFONES AT THE 9-POSITION |
US7030109B2 (en) | 1999-07-19 | 2006-04-18 | Pharmacia & Upjohn Company | 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2313721A1 (en) | 1973-03-20 | 1974-10-03 | Bayer Ag | NEW 1-PHENYL-SUBSTITUTED 1,3,5TRIAZINE, THE METHOD FOR THEIR MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT |
DE2509037A1 (en) | 1975-03-01 | 1976-09-02 | Bayer Ag | 1-(4-(arylthio-or aryloxy) phenyl) uracils - coccidiocides for use in mammals as well as poultry, and for treatment of ioxoplasmosis |
DE3408924A1 (en) * | 1984-03-12 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-3,5-DIONE, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING IT AND THEIR USE |
DE3531919A1 (en) * | 1985-09-07 | 1987-03-19 | Hoechst Ag | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-3,5-DIONE, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING IT AND THEIR USE |
DE4120138A1 (en) * | 1991-06-19 | 1992-12-24 | Bayer Ag | SUBSTITUTED HEXAHYDRO-1,2,4-TRIAZINDIONES, METHOD FOR THE PRODUCTION THEREOF, INTERMEDIATE PRODUCTS THEREOF AND THEIR USE |
EP0476439A1 (en) * | 1990-09-18 | 1992-03-25 | Bayer Ag | Substituted 1,2,4-triazindiones, method for their preparation, intermdiates for it and their use |
DE19606594A1 (en) * | 1996-02-22 | 1997-08-28 | Bayer Ag | Substituted 2-aryl-1,2,4-triazine-3,5-di (thi) one |
US6867207B2 (en) | 1997-07-10 | 2005-03-15 | Janssen Pharmaceutica N.V. | IL-5 inhibiting 6-azauracil derivatives |
KR20010014049A (en) * | 1997-07-10 | 2001-02-26 | 디르크 반테 | Il-5 inhibiting 6-azauracil derivatives |
SK8152001A3 (en) | 1998-12-18 | 2002-04-04 | Janssen Pharmaceutica Nv | Il-5 inhibiting 6-azauracil derivatives |
US6787652B1 (en) | 1999-09-30 | 2004-09-07 | Pfizer, Inc. | 6-Azauracil derivatives as thyroid receptor ligands |
-
1971
- 1971-10-05 DE DE19712149645 patent/DE2149645A1/en active Pending
- 1971-10-06 CA CA124,565A patent/CA992538A/en not_active Expired
- 1971-10-06 ES ES395778A patent/ES395778A1/en not_active Expired
- 1971-10-06 BR BR6641/71A patent/BR7106641D0/en unknown
- 1971-10-06 IL IL37861A patent/IL37861A0/en unknown
- 1971-10-07 HU HUPI356A patent/HU166467B/hu unknown
- 1971-10-07 CH CH128973A patent/CH566328A5/xx not_active IP Right Cessation
- 1971-10-07 BE BE773583A patent/BE773583A/en unknown
- 1971-10-07 IT IT53324/71A patent/IT1050658B/en active
- 1971-10-07 FR FR7136162A patent/FR2110283A1/en active Granted
- 1971-10-07 AR AR238356A patent/AR195271A1/en active
- 1971-10-07 CH CH1465571A patent/CH563375A5/xx not_active IP Right Cessation
- 1971-10-07 NL NL7113797A patent/NL7113797A/xx unknown
-
1973
- 1973-02-09 AR AR246511A patent/AR196001A1/en active
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0331232A3 (en) * | 1988-02-29 | 1991-04-24 | Janssen Pharmaceutica N.V. | 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols |
WO2001005793A1 (en) * | 1999-07-19 | 2001-01-25 | Pharmacia & Upjohn Company | 1,2,3,4,5,6-HEXAHYDROAZEPINO[4,5-b]INDOLES CONTAINING ARYLSULFONES AT THE 9-POSITION |
US6468999B1 (en) | 1999-07-19 | 2002-10-22 | Pharmacia & Upjohn Company | 1,2,3,4,5,6,-hexahydroazepino [4,5-b]indoles containing arylsulfones at the 9-position |
US6878823B2 (en) | 1999-07-19 | 2005-04-12 | Pharmacia & Upjohn Company | 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position |
US6921823B2 (en) | 1999-07-19 | 2005-07-26 | Pharmacia & Upjohn Company Llc | 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position |
US7030109B2 (en) | 1999-07-19 | 2006-04-18 | Pharmacia & Upjohn Company | 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position |
Also Published As
Publication number | Publication date |
---|---|
AR196001A1 (en) | 1973-11-23 |
CA992538A (en) | 1976-07-06 |
HU166467B (en) | 1975-03-28 |
BR7106641D0 (en) | 1973-02-22 |
IL37861A0 (en) | 1971-12-29 |
IT1050658B (en) | 1981-03-20 |
AR195271A1 (en) | 1973-09-28 |
BE773583A (en) | 1972-04-07 |
CH563375A5 (en) | 1975-06-30 |
DE2149645A1 (en) | 1972-09-14 |
ES395778A1 (en) | 1974-10-01 |
CH566328A5 (en) | 1975-09-15 |
NL7113797A (en) | 1972-04-11 |
FR2110283B1 (en) | 1975-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |