FR2100890A1 - 3, 4- dihydro-2 (1h)-quin azolinones - anti-inflammatories and analge - Google Patents

3, 4- dihydro-2 (1h)-quin azolinones - anti-inflammatories and analge

Info

Publication number
FR2100890A1
FR2100890A1 FR7125249A FR7125249A FR2100890A1 FR 2100890 A1 FR2100890 A1 FR 2100890A1 FR 7125249 A FR7125249 A FR 7125249A FR 7125249 A FR7125249 A FR 7125249A FR 2100890 A1 FR2100890 A1 FR 2100890A1
Authority
FR
France
Prior art keywords
azolinones
analge
quin
inflammatories
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7125249A
Other languages
French (fr)
Other versions
FR2100890B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP6161870A external-priority patent/JPS4821951B1/ja
Priority claimed from JP45098107A external-priority patent/JPS4821954B1/ja
Priority claimed from JP11833270A external-priority patent/JPS4834598B1/ja
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of FR2100890A1 publication Critical patent/FR2100890A1/en
Application granted granted Critical
Publication of FR2100890B1 publication Critical patent/FR2100890B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80—Oxygen atoms
    • C07D239/82—Oxygen atoms with an aryl radical attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The novel title cpds are of formula: (in which R1 and R2 are H, lower alkyl, lower alkoxy NO2, CF3, lowre alkylthio, lower alkylsulphonyl or halogen, R3 is -C6H4-R4 (where R4 is H, lower alkyl, lower alkoxyl, NO2 or halogen), naphthyl, lower cycloalkyl, lower cycloalkenyl, pyridyl pyrrolyl thienyl or furyl; R is lower cycloalkyl, trihalomethyl, lower alkoxy, lower alkylthio, lower alkanoyloxy, or -NR5R6 or -CONR5R6 (where R5 and R6 are lower alkyl or together with the adjacent N atom from a pentagonal or hexagonal opt. substd heterocyclic ring which may contain N, O or S as additional heteratoms) and n is 1-3).
FR7125249A 1970-07-13 1971-07-09 3, 4- dihydro-2 (1h)-quin azolinones - anti-inflammatories and analge Granted FR2100890A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP6161870A JPS4821951B1 (en) 1970-07-13 1970-07-13
JP9630670 1970-10-30
JP45098107A JPS4821954B1 (en) 1970-11-05 1970-11-05
JP11833270A JPS4834598B1 (en) 1970-12-23 1970-12-23

Publications (2)

Publication Number Publication Date
FR2100890A1 true FR2100890A1 (en) 1972-03-24
FR2100890B1 FR2100890B1 (en) 1975-06-06

Family

ID=27464063

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7125249A Granted FR2100890A1 (en) 1970-07-13 1971-07-09 3, 4- dihydro-2 (1h)-quin azolinones - anti-inflammatories and analge

Country Status (8)

Country Link
BE (1) BE769858A (en)
CA (1) CA956958A (en)
CH (1) CH560693A5 (en)
DE (1) DE2134118C3 (en)
DK (1) DK129348B (en)
FR (1) FR2100890A1 (en)
NL (1) NL169589C (en)
SE (1) SE380019B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071516A (en) 1976-08-20 1978-01-31 Sandoz, Inc. 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1932396A1 (en) * 1968-07-01 1970-01-08 Sandoz Ag Heterocyclic compounds and processes for their preparation
NL6918486A (en) * 1968-12-10 1970-06-12
CH499545A (en) * 1970-04-27 1970-11-30 Sandoz Ag 4-thienyl-2 (1h)-quinazolinones prodn
FR2060075A1 (en) * 1969-08-02 1971-06-11 Sumitomo Chemical Co

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1932396A1 (en) * 1968-07-01 1970-01-08 Sandoz Ag Heterocyclic compounds and processes for their preparation
NL6918486A (en) * 1968-12-10 1970-06-12
FR2060075A1 (en) * 1969-08-02 1971-06-11 Sumitomo Chemical Co
CH499545A (en) * 1970-04-27 1970-11-30 Sandoz Ag 4-thienyl-2 (1h)-quinazolinones prodn

Also Published As

Publication number Publication date
CH560693A5 (en) 1975-04-15
DK129348B (en) 1974-09-30
BE769858A (en) 1971-11-16
CA956958A (en) 1974-10-29
NL7109637A (en) 1972-01-17
NL169589C (en) 1982-08-02
FR2100890B1 (en) 1975-06-06
DK129348C (en) 1975-02-24
NL169589B (en) 1982-03-01
DE2134118A1 (en) 1972-01-20
DE2134118B2 (en) 1974-08-15
DE2134118C3 (en) 1975-04-10
AU3110171A (en) 1973-01-18
SE380019B (en) 1975-10-27

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Legal Events

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