SE8600742L - TREATMENT - Google Patents

TREATMENT

Info

Publication number
SE8600742L
SE8600742L SE8600742A SE8600742A SE8600742L SE 8600742 L SE8600742 L SE 8600742L SE 8600742 A SE8600742 A SE 8600742A SE 8600742 A SE8600742 A SE 8600742A SE 8600742 L SE8600742 L SE 8600742L
Authority
SE
Sweden
Prior art keywords
alkoxy
aryl
alkyl
contg
opt
Prior art date
Application number
SE8600742A
Other languages
Swedish (sv)
Other versions
SE8600742A0 (en
SE8600742D0 (en
Inventor
A E Brendstrom
P L Lindberg
G E Sunden
B M G Wallmark
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of SE8600742D0 publication Critical patent/SE8600742D0/en
Publication of SE8600742A0 publication Critical patent/SE8600742A0/en
Publication of SE8600742L publication Critical patent/SE8600742L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Treatment comprises administering a 2- (1-2-pyridyl) alkylsulphinyl) -benzyimidazole of formula (I) or its salt: R1-R4 = H, halogen, CN, CF3, -COR11, -O-CO-R12, -CH(OR13)2, -(Z)n-A-D, up to 10C aryl, up to 10C aryloxy, 1-6C alkylthio, NO2 or 1-6C alkylsulphinyl, or two of R1-R4 can together form a fixed 5-7 membered monocyclic or 9-11 membered bicyclic (un)satd. ring contg. 0-3 O or N heteroatoms, opt. substd. or R1, R2, R2/R3 or R3/R4 can complete two rings opt. fused with each other; R11 and R12 = up to 10C aryl, 1-4C alkoxy, 1-3C alkoxy 1-3C alkoxy, (up to 10C)aryl-(1-20) alkoxy, up to 10C aryloxy, di-(1-3C) alkylamino, or pyrrolidino or piperidino both opt. substd. ; R13 = 1-4C alkyl or 2-3C alkylene; Z = O or CO; n = 0 or 1; A = 1-6C alkylene, 3-6C cycloalkylene, 2-6C alkylene, 3-6C cycloalkylene or 2-6C alkynylene; D = H, CH (sic), -CO-R9 or -(Y)-(CO)r-R10; R9 = 1-5C alkoxyor di(1-3C) alkylamino; m and r = 0 or 1; Y = O or NR10; R10 = H, 1-3C alkyl, (up to 10C) aryl -(1-2C) alkyl or up to 10C aryl; R5 = H, CH3 or C2H5; R6 and R8 = H or 1-6C alkyl; R7 = H, 1-8C alkyl, 1-8C alkoxy, 2-5C alkenyloxy, 2-5C alkynyloxy, (1-2C) alkoxy (1-2C) alkoxy, (up to 10C) aryl-(1-6C)alkyl, up to 10C aryloxy (opt. substd.), (up to 10C) aryl (1-6C) alkoxy, di-(1-2C) alkylamino-(1-4C) alkoxy, oxycycloalkyl contg. one O and 3-7C, oxacycloalkoxy contg. two O and 4-7C, oxacycloalkylalkyl contg. one O and 4-7C or oxacycloalkylalkoxy contg. one O and 4-7C; or R6 + R7 or R7 + R8 = -CH=CH-CH=CH-, -O(CH2)p- -S(CH2)v-, -CH2(CH2)p-, -O-CH=CH-, -NH-CH=CH- or -N(Me)-CH=CH-p=2-4; v=2,3.
SE8600742A 1985-03-01 1986-02-19 TREATMENT SE8600742L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8500995A SE8500995D0 (en) 1985-03-01 1985-03-01 METHOD OF TREATMENT

Publications (3)

Publication Number Publication Date
SE8600742D0 SE8600742D0 (en) 1986-02-19
SE8600742A0 SE8600742A0 (en) 1986-09-02
SE8600742L true SE8600742L (en) 1986-09-02

Family

ID=20359317

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8500995A SE8500995D0 (en) 1985-03-01 1985-03-01 METHOD OF TREATMENT
SE8600742A SE8600742L (en) 1985-03-01 1986-02-19 TREATMENT

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE8500995A SE8500995D0 (en) 1985-03-01 1985-03-01 METHOD OF TREATMENT

Country Status (1)

Country Link
SE (2) SE8500995D0 (en)

Also Published As

Publication number Publication date
SE8600742A0 (en) 1986-09-02
SE8500995D0 (en) 1985-03-01
SE8600742D0 (en) 1986-02-19

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