SE8400688D0 - NOVEL PHARMACOLOGICALLY ACTIVE COMPOUNDS - Google Patents
NOVEL PHARMACOLOGICALLY ACTIVE COMPOUNDSInfo
- Publication number
- SE8400688D0 SE8400688D0 SE8400688A SE8400688A SE8400688D0 SE 8400688 D0 SE8400688 D0 SE 8400688D0 SE 8400688 A SE8400688 A SE 8400688A SE 8400688 A SE8400688 A SE 8400688A SE 8400688 D0 SE8400688 D0 SE 8400688D0
- Authority
- SE
- Sweden
- Prior art keywords
- alkoxy
- aryl
- alkyl
- alkylamino
- opt
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 10
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- 125000003118 aryl group Chemical group 0.000 abstract 9
- 125000003282 alkyl amino group Chemical group 0.000 abstract 5
- 125000002947 alkylene group Chemical group 0.000 abstract 3
- 125000004104 aryloxy group Chemical group 0.000 abstract 3
- 125000002993 cycloalkylene group Chemical group 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000004419 alkynylene group Chemical group 0.000 abstract 1
- 125000005133 alkynyloxy group Chemical group 0.000 abstract 1
- 125000001769 aryl amino group Chemical group 0.000 abstract 1
- 125000003785 benzimidazolyl group Chemical group N1=C(NC2=C1C=CC=C2)* 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000002112 pyrrolidino group Chemical group [*]N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 102220216906 rs1060505002 Human genes 0.000 abstract 1
- 102220260512 rs1192077362 Human genes 0.000 abstract 1
- 102220264750 rs1305455942 Human genes 0.000 abstract 1
- 102220012898 rs397516346 Human genes 0.000 abstract 1
- 102220095236 rs876658436 Human genes 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Cpds. of formula (I) and their salts when X is S are new:- X=S or -S(O)-; R15=H, CH3 or C2H5; R1, R2, R3, R4=same or different H, halo, CN, -CHO, CF3, -COR'', -CH(OR13)2, -(Z)n-A-D, aryl, aryloxy, 1-6C alkylthio, NO2, 1-6C alkylsulphinyl or adjacent gps. R1, R2, R3, R4 together form a 5,6 or 7 membered monocyclic ring or 9, 10 or 11 membered bicyclic Mg both opt. unsatd. and opt. contg. 0 to 3 of N and/or O fused to the benzimidazole ring. R11 and R12=same or different aryl, 1-4C alkoxy, 1-3C alkoxy (1-3C) alkoxy, aryl (1-2C) alkoxy, aryloxy, di(1-3C)alkylamino, pyrrolidino or piperidino both opt. substd. by 1-3C alkyl; R13=1-4C alkyl or 2-3C alkylene; Z=-O- or -C(=O)-; L=0 or 1; A=1-6C alkylene, 3-6C cycloalkylene, 2-6C alkylene, 3-6C cycloalkylene or 2-6C alkynylene; D=CN, -C(=O)R9, -(Y)m-(C=O)r-R16; R9=1-5C alkoxy or di(1-3C)alkylamino; m=O or 1; r=O or 1; y=-O-, -NH-, -NR10-; R10=H, 1-3C alkyl, aryl(1-2C) alkyl or aryl; R5=H or -CO-R14; R14=1-6C alkyl, aryl(1-2C) alkyl, aryl, 1-4C alkoxy, aryl(1-2C) alkyl, aryloxy, amino, mono- or di-(1-4C) alkylamino, aryl(1-2C) alkylamino or arylamino; R6 and R8=same or different H, or 1-5C alkyl; R7=1-8C alkyl, 1-8C alkoxy, 2-5C alkenyloxy, 2-5C alkynyloxy, 1-2C alkoxy (1-2C) alkoxy, di(1-2C) alkylamino (1-4C) alkoxy, 3-7C oxacycloalkyl, 4-7C oxacycloalkoxy, 4-7C oxacycloalkylalkyl, 4-6C oxacycloalkylalkoxy R6 and R7 or R7 and R8 together with the adjacent carbon atoms in the pyridine form a ring where R6 and R7 or R7 and R8 is -CH=CH-CH=CH-, -O-(CH2)p-, -CH2(CH2)p-, -O-CH=CH-, -NH-CH=CH- or -N(CH3)CH=CH- p=2,3 or 4.(0/0)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8400688A SE8400688L (en) | 1983-02-11 | 1984-02-09 | NEW PHARMACOLOGICALLY ACTIVE SOCIETIES |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8300736A SE8300736D0 (en) | 1983-02-11 | 1983-02-11 | NOVEL PHARMACOLOGICALLY ACTIVE COMPOUNDS |
| SE8400688A SE8400688L (en) | 1983-02-11 | 1984-02-09 | NEW PHARMACOLOGICALLY ACTIVE SOCIETIES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8400688D0 true SE8400688D0 (en) | 1984-02-09 |
| SE8400688L SE8400688L (en) | 1984-08-12 |
Family
ID=26658388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8400688A SE8400688L (en) | 1983-02-11 | 1984-02-09 | NEW PHARMACOLOGICALLY ACTIVE SOCIETIES |
Country Status (1)
| Country | Link |
|---|---|
| SE (1) | SE8400688L (en) |
-
1984
- 1984-02-09 SE SE8400688A patent/SE8400688L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SE8400688L (en) | 1984-08-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2147056A1 (en) | Novel delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides | |
| ES8609264A1 (en) | 3-Amino-1-benzazepin-2-one-1-alcanoic acids, process for their preparation, their pharmaceutical preparation as well as their therapeutic use. | |
| ES8601213A1 (en) | Cephalosporin derivatives. | |
| ES8406080A1 (en) | Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same. | |
| ES8404990A1 (en) | Anti-hypertensive prolinol-based peptides. | |
| FI956237A0 (en) | Process for the preparation of aromatic olefins | |
| ES2010071A6 (en) | Isoquinoline derivatives and their use | |
| ES8604571A1 (en) | Indole-3-carboxamide derivatives. | |
| DE3878235D1 (en) | ANTISCHIZOPHREN EFFECTIVE S-N- (1-AZABICYCLO (2.2.2.) OCT-3-YL) BENZAMIDES AND THIOBENZAMIDES. | |
| DE3781174D1 (en) | USE OF AROMATIC DIAMINES FOR THE TREATMENT OF ANGINA PECTORIS AND DIAMINE DAFUER. | |
| SE8400688D0 (en) | NOVEL PHARMACOLOGICALLY ACTIVE COMPOUNDS | |
| ES8601963A1 (en) | (1H-tetrazol-5-yl)-2(1H)-quinolinones. | |
| ES8506622A1 (en) | 1,3-Di:substd.-2-carboxy -di:hydroxy-alkyl-indole derivs. | |
| IL91648A (en) | Amino acid quinoline and naphthyridine derivatives, their preparation and pharmaceutical compositions containing them | |
| EP0233291A4 (en) | 2-arylbenzothiazine derivatives. | |
| SG43064A1 (en) | New 3 4-dihydroisoquinoline derivatives and new pharmaceutical use of carbocyclically and heterocyclically fused dihydropyfidines | |
| SE8600742L (en) | TREATMENT | |
| ES8604149A1 (en) | 1,4-Dihydropyridines, method for their preparation and their use as medicaments. | |
| EG18031A (en) | Dihydropyridiniellactols,process for their preparation and their use as medicaments | |
| EP0089635A3 (en) | Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same | |
| FR2248050A1 (en) | 4,5-dihydro-4h-s-triazolo (4,3-a) (1,4) benzodiazepine - cns depressants, anti-convulsants, anti-aggressives and somatic reflex in | |
| SE8802997L (en) | AMINERY DERIVATIVES AND ITS SALT, PROCEDURES FOR PREPARING THEREOF AND Means against their containing | |
| EP0042232A3 (en) | Cephalosporin derivatives, processes for their preparation and compositions containing them | |
| FR2194424A1 (en) | Trialkoxybenzoylpeptide derivs - for treatment of cardiac disorders | |
| ES8802320A1 (en) | Pyridazo (1, 2-a)(1, 2) diazepine derivative |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8400688-1 Effective date: 19900917 Format of ref document f/p: F |