FR2400504A1 - Leuco-anthraquinones et leurs formes tautomeres, leurs procedes de preparation et leur utilisation pour lutter contre les maladies cancereuses - Google Patents

Leuco-anthraquinones et leurs formes tautomeres, leurs procedes de preparation et leur utilisation pour lutter contre les maladies cancereuses

Info

Publication number
FR2400504A1
FR2400504A1 FR7823503A FR7823503A FR2400504A1 FR 2400504 A1 FR2400504 A1 FR 2400504A1 FR 7823503 A FR7823503 A FR 7823503A FR 7823503 A FR7823503 A FR 7823503A FR 2400504 A1 FR2400504 A1 FR 2400504A1
Authority
FR
France
Prior art keywords
anthraquinones
leuco
preparation
methods
control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7823503A
Other languages
English (en)
Other versions
FR2400504B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27542240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2400504(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US05/903,292 external-priority patent/US4138415A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FR2400504A1 publication Critical patent/FR2400504A1/fr
Application granted granted Critical
Publication of FR2400504B1 publication Critical patent/FR2400504B1/fr
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J45/00—Ion-exchange in which a complex or a chelate is formed; Use of material as complex or chelate forming ion-exchangers; Treatment of material for improving the complex or chelate forming ion-exchange properties
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G59/00—Polycondensates containing more than one epoxy group per molecule; Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
    • C08G59/18—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing
    • C08G59/40—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing characterised by the curing agents used
    • C08G59/62—Alcohols or phenols
    • C08G59/621—Phenols
    • C08G59/623—Aminophenols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G59/00—Polycondensates containing more than one epoxy group per molecule; Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
    • C08G59/18—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing
    • C08G59/68—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing characterised by the catalysts used
    • C08G59/686—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing characterised by the catalysts used containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M1/00—Liquid compositions essentially based on mineral lubricating oils or fatty oils; Their use as lubricants
    • C10M1/08—Liquid compositions essentially based on mineral lubricating oils or fatty oils; Their use as lubricants with additives
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M133/00—Lubricating compositions characterised by the additive being an organic non-macromolecular compound containing nitrogen
    • C10M133/02—Lubricating compositions characterised by the additive being an organic non-macromolecular compound containing nitrogen having a carbon chain of less than 30 atoms
    • C10M133/04—Amines, e.g. polyalkylene polyamines; Quaternary amines
    • C10M133/12—Amines, e.g. polyalkylene polyamines; Quaternary amines having amino groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

L'invention concerne des nouveaux composés chimiques, répondant à la formule générale suivante :
FR7823503A 1977-08-15 1978-08-09 Leuco-anthraquinones et leurs formes tautomeres, leurs procedes de preparation et leur utilisation pour lutter contre les maladies cancereuses Granted FR2400504A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US82487277A 1977-08-15 1977-08-15
US87317478A 1978-01-30 1978-01-30
US87304078A 1978-01-30 1978-01-30
US87304178A 1978-01-30 1978-01-30
US05/903,292 US4138415A (en) 1978-05-05 1978-05-05 1,4-Bis(aminoalkylamino)-anthraquinones and leuco derivatives thereof

Publications (2)

Publication Number Publication Date
FR2400504A1 true FR2400504A1 (fr) 1979-03-16
FR2400504B1 FR2400504B1 (fr) 1981-06-26

Family

ID=27542240

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7823503A Granted FR2400504A1 (fr) 1977-08-15 1978-08-09 Leuco-anthraquinones et leurs formes tautomeres, leurs procedes de preparation et leur utilisation pour lutter contre les maladies cancereuses

Country Status (22)

Country Link
JP (1) JPS6463556A (fr)
AR (1) AR225884A1 (fr)
AT (1) AT359484B (fr)
AU (1) AU527103B2 (fr)
BE (1) BE869688A (fr)
CH (1) CH644840A5 (fr)
DD (1) DD139256A5 (fr)
DE (1) DE2835661A1 (fr)
DK (1) DK158836C (fr)
FI (1) FI70882C (fr)
FR (1) FR2400504A1 (fr)
GB (1) GB2004293B (fr)
GR (1) GR74415B (fr)
IE (1) IE47253B1 (fr)
IL (1) IL55218A (fr)
IT (1) IT1107773B (fr)
NL (1) NL188981C (fr)
NO (2) NO148777C (fr)
NZ (1) NZ187989A (fr)
PL (1) PL122586B1 (fr)
PT (1) PT68420A (fr)
SE (1) SE445996B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4275009A (en) * 1979-05-29 1981-06-23 American Cyanamid Company 1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones
US4275010A (en) * 1979-10-24 1981-06-23 American Cyanamid Company 5,8-Dihydroxy-1,4-bis(guanidinylamino)anthraquinones
US4296030A (en) * 1980-04-09 1981-10-20 American Cyanamid Company Metal chelates of 1,4-bis(substituted-amino-5,8-dihydroxy-anthraquinones
US4278605A (en) * 1980-06-30 1981-07-14 American Cyanamid Company Heteroalkylenebisanthraquinones
EP0052853A1 (fr) * 1980-11-24 1982-06-02 Hoechst Aktiengesellschaft Dérivés de la bis-aminométhyl-anthraquinone, leur procédé de préparation, compositions les contenant et leur application
EP0083683A1 (fr) * 1981-10-26 1983-07-20 American Cyanamid Company Procédé pour préparer de 1,4-bis(amino substitués)-5,8-dihydroxy-anthraquinones et compositions pharmaceutiques les contenant
ATE48942T1 (de) * 1984-02-27 1990-01-15 American Cyanamid Co Verwendung von 1,4 bisubstituierten anthrachinonen zur herstellung von immunsuppressiva.
EP0182135A3 (fr) * 1984-11-19 1987-08-05 American Cyanamid Company Aminoanthraquinones bis-N-substituées
US5436243A (en) * 1993-11-17 1995-07-25 Research Triangle Institute Duke University Aminoanthraquinone derivatives to combat multidrug resistance
GB9815910D0 (en) * 1998-07-21 1998-09-23 Btg Int Ltd Synthetic method
WO2005061453A1 (fr) * 2003-12-23 2005-07-07 Somanta Limited Utilisation de composes d'anthraquinone en tant que composes anticancereux
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
EP2376514A2 (fr) 2008-12-23 2011-10-19 Pharmasset, Inc. Analogues de nucléoside
MX2011006891A (es) 2008-12-23 2011-10-06 Pharmasset Inc Fosforamidatos de nucleosidos.
NZ593647A (en) 2008-12-23 2013-08-30 Gilead Pharmasset Llc Synthesis of purine nucleosides
AU2011235112B2 (en) 2010-03-31 2015-07-09 Gilead Pharmasset Llc Nucleoside phosphoramidates
DE102012203981A1 (de) * 2012-03-14 2013-09-19 Henkel Ag & Co. Kgaa Mittel zum Färben und/oder Mattieren von keratinhaltigen Fasern enthaltend neuartige1,4-Diaminoanthrachinonfarbstoffe
GB201214169D0 (en) 2012-08-08 2012-09-19 Biostatus Ltd New compounds and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1422016A (fr) * 1962-10-29 1965-12-24 Oreal Nouveaux colorants anthraquinoniques et leur application à la teinture des cheveux
GB1157506A (en) * 1965-09-10 1969-07-09 Ilford Ltd Anthraquinone Dye Colour Couplers and their use in Colour Photographic Materials
US3646072A (en) * 1970-07-27 1972-02-29 Du Pont Turquoise biscationic anthraquinone dyes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700398A (en) * 1970-07-27 1972-10-24 Du Pont Process for dyeing acid-modified nylon fibers
US4051155A (en) * 1975-12-15 1977-09-27 Allied Chemical Corporation Anthraquinone dyes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1422016A (fr) * 1962-10-29 1965-12-24 Oreal Nouveaux colorants anthraquinoniques et leur application à la teinture des cheveux
GB1157506A (en) * 1965-09-10 1969-07-09 Ilford Ltd Anthraquinone Dye Colour Couplers and their use in Colour Photographic Materials
US3646072A (en) * 1970-07-27 1972-02-29 Du Pont Turquoise biscationic anthraquinone dyes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NV6015C/68 *

Also Published As

Publication number Publication date
DD139256A5 (de) 1979-12-19
DK358678A (da) 1979-02-16
PL209065A1 (fr) 1980-01-02
DK158836C (da) 1991-01-14
SE7807987L (sv) 1979-02-16
JPS6463556A (en) 1989-03-09
GR74415B (fr) 1984-06-28
IE781636L (en) 1979-02-15
ATA590678A (de) 1980-04-15
FI782481A (fi) 1979-02-16
FR2400504B1 (fr) 1981-06-26
FI70882C (fi) 1986-10-27
NL7808475A (nl) 1979-02-19
PT68420A (en) 1978-09-01
IL55218A (en) 1983-03-31
IE47253B1 (en) 1984-02-08
DE2835661A1 (de) 1979-03-01
NO782756L (no) 1979-02-16
JPH0217534B2 (fr) 1990-04-20
NZ187989A (en) 1981-07-13
AU3877678A (en) 1980-02-14
NO148777B (no) 1983-09-05
AU527103B2 (en) 1983-02-17
DE2835661C2 (fr) 1991-08-22
IT1107773B (it) 1985-11-25
NO820290L (no) 1979-02-16
BE869688A (fr) 1979-02-12
GB2004293B (en) 1982-06-23
NO150482C (no) 1984-10-24
PL122586B1 (en) 1982-08-31
FI70882B (fi) 1986-07-18
NO148777C (no) 1984-01-25
SE445996B (sv) 1986-08-04
NL188981C (nl) 1992-12-01
DK158836B (da) 1990-07-23
CH644840A5 (de) 1984-08-31
AT359484B (de) 1980-11-10
AR225884A1 (es) 1982-05-14
GB2004293A (en) 1979-03-28
IT7850730A0 (it) 1978-08-14
NO150482B (no) 1984-07-16

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0313, 920526

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0313, 780809

CL Concession to grant licences