AU527103B2 - Amino anthraquinones and their leuco-forms, and use to inhibit cancers - Google Patents

Amino anthraquinones and their leuco-forms, and use to inhibit cancers

Info

Publication number
AU527103B2
AU527103B2 AU38776/78A AU3877678A AU527103B2 AU 527103 B2 AU527103 B2 AU 527103B2 AU 38776/78 A AU38776/78 A AU 38776/78A AU 3877678 A AU3877678 A AU 3877678A AU 527103 B2 AU527103 B2 AU 527103B2
Authority
AU
Australia
Prior art keywords
leuco
forms
amino anthraquinones
inhibit cancers
cancers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU38776/78A
Other versions
AU3877678A (en
Inventor
Frederick Emil Durrand Ralph Grussing Child Keith Chadwick Murdock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27542240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU527103(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US05/903,292 external-priority patent/US4138415A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of AU3877678A publication Critical patent/AU3877678A/en
Application granted granted Critical
Publication of AU527103B2 publication Critical patent/AU527103B2/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J45/00—Ion-exchange in which a complex or a chelate is formed; Use of material as complex or chelate forming ion-exchangers; Treatment of material for improving the complex or chelate forming ion-exchange properties
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G59/00—Polycondensates containing more than one epoxy group per molecule; Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
    • C08G59/18—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing
    • C08G59/40—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing characterised by the curing agents used
    • C08G59/62—Alcohols or phenols
    • C08G59/621—Phenols
    • C08G59/623—Aminophenols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G59/00—Polycondensates containing more than one epoxy group per molecule; Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
    • C08G59/18—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing
    • C08G59/68—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing characterised by the catalysts used
    • C08G59/686—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing characterised by the catalysts used containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M1/00—Liquid compositions essentially based on mineral lubricating oils or fatty oils; Their use as lubricants
    • C10M1/08—Liquid compositions essentially based on mineral lubricating oils or fatty oils; Their use as lubricants with additives
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M133/00—Lubricating compositions characterised by the additive being an organic non-macromolecular compound containing nitrogen
    • C10M133/02—Lubricating compositions characterised by the additive being an organic non-macromolecular compound containing nitrogen having a carbon chain of less than 30 atoms
    • C10M133/04—Amines, e.g. polyalkylene polyamines; Quaternary amines
    • C10M133/12—Amines, e.g. polyalkylene polyamines; Quaternary amines having amino groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AU38776/78A 1977-08-15 1978-08-09 Amino anthraquinones and their leuco-forms, and use to inhibit cancers Expired AU527103B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US82487277A 1977-08-15 1977-08-15
USUS824872 1977-08-15
US87304078A 1978-01-30 1978-01-30
US87304178A 1978-01-30 1978-01-30
US87317478A 1978-01-30 1978-01-30
US05/903,292 US4138415A (en) 1978-05-05 1978-05-05 1,4-Bis(aminoalkylamino)-anthraquinones and leuco derivatives thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU90823/82A Division AU537927B2 (en) 1977-08-15 1982-11-23 Substituted alkylamino-anthraquinones

Publications (2)

Publication Number Publication Date
AU3877678A AU3877678A (en) 1980-02-14
AU527103B2 true AU527103B2 (en) 1983-02-17

Family

ID=27542240

Family Applications (1)

Application Number Title Priority Date Filing Date
AU38776/78A Expired AU527103B2 (en) 1977-08-15 1978-08-09 Amino anthraquinones and their leuco-forms, and use to inhibit cancers

Country Status (22)

Country Link
JP (1) JPS6463556A (en)
AR (1) AR225884A1 (en)
AT (1) AT359484B (en)
AU (1) AU527103B2 (en)
BE (1) BE869688A (en)
CH (1) CH644840A5 (en)
DD (1) DD139256A5 (en)
DE (1) DE2835661A1 (en)
DK (1) DK158836C (en)
FI (1) FI70882C (en)
FR (1) FR2400504A1 (en)
GB (1) GB2004293B (en)
GR (1) GR74415B (en)
IE (1) IE47253B1 (en)
IL (1) IL55218A (en)
IT (1) IT1107773B (en)
NL (1) NL188981C (en)
NO (2) NO148777C (en)
NZ (1) NZ187989A (en)
PL (1) PL122586B1 (en)
PT (1) PT68420A (en)
SE (1) SE445996B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4275009A (en) * 1979-05-29 1981-06-23 American Cyanamid Company 1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones
US4275010A (en) * 1979-10-24 1981-06-23 American Cyanamid Company 5,8-Dihydroxy-1,4-bis(guanidinylamino)anthraquinones
US4296030A (en) * 1980-04-09 1981-10-20 American Cyanamid Company Metal chelates of 1,4-bis(substituted-amino-5,8-dihydroxy-anthraquinones
US4278605A (en) * 1980-06-30 1981-07-14 American Cyanamid Company Heteroalkylenebisanthraquinones
EP0052853A1 (en) * 1980-11-24 1982-06-02 Hoechst Aktiengesellschaft Bis-aminomethyl-anthraquinone derivatives, process for their manufacture, compositions containing them and their use
EP0083683A1 (en) * 1981-10-26 1983-07-20 American Cyanamid Company Method of preparing 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones and pharmaceutical compositions containing them
EP0154117B1 (en) * 1984-02-27 1989-12-27 American Cyanamid Company Use of 1,4 bis(substituted) anthrachinones for the manufacture of immunosuppresiva
EP0182135A3 (en) * 1984-11-19 1987-08-05 American Cyanamid Company Novel bis-(substituted amino) anthraquinones
US5436243A (en) * 1993-11-17 1995-07-25 Research Triangle Institute Duke University Aminoanthraquinone derivatives to combat multidrug resistance
GB9815910D0 (en) 1998-07-21 1998-09-23 Btg Int Ltd Synthetic method
US7557215B2 (en) * 2003-12-23 2009-07-07 Somanta Limited Anthraquinone compounds as anti cancer compounds
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
WO2010075517A2 (en) 2008-12-23 2010-07-01 Pharmasset, Inc. Nucleoside analogs
SG172363A1 (en) 2008-12-23 2011-07-28 Pharmasset Inc Synthesis of purine nucleosides
CL2009002207A1 (en) 2008-12-23 2011-02-18 Gilead Pharmasset Llc Compounds derived from 3-hydroxy-5- (9h-purin-9-yl) tetrahydrofuran-2-yl, an inhibitor of the replication of arn-dependent viral arn; pharmaceutical composition; use for the treatment of hepatitis c.
AP3515A (en) 2010-03-31 2016-01-11 Gilead Pharmasset Llc Nucleoside phosphoramidates
DE102012203981A1 (en) * 2012-03-14 2013-09-19 Henkel Ag & Co. Kgaa Agent for dyeing and / or delustering keratin-containing fibers containing novel 1,4-diaminoanthraquinone dyes
GB201214169D0 (en) 2012-08-08 2012-09-19 Biostatus Ltd New compounds and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1422016A (en) * 1962-10-29 1965-12-24 Oreal New anthraquinone dyes and their application to hair dye
GB1157506A (en) * 1965-09-10 1969-07-09 Ilford Ltd Anthraquinone Dye Colour Couplers and their use in Colour Photographic Materials
US3700398A (en) * 1970-07-27 1972-10-24 Du Pont Process for dyeing acid-modified nylon fibers
US3646072A (en) * 1970-07-27 1972-02-29 Du Pont Turquoise biscationic anthraquinone dyes
US4051155A (en) * 1975-12-15 1977-09-27 Allied Chemical Corporation Anthraquinone dyes

Also Published As

Publication number Publication date
FR2400504A1 (en) 1979-03-16
IE47253B1 (en) 1984-02-08
FR2400504B1 (en) 1981-06-26
JPS6463556A (en) 1989-03-09
IT1107773B (en) 1985-11-25
FI70882C (en) 1986-10-27
FI782481A (en) 1979-02-16
DK158836C (en) 1991-01-14
IT7850730A0 (en) 1978-08-14
DD139256A5 (en) 1979-12-19
IE781636L (en) 1979-02-15
NO820290L (en) 1979-02-16
PL209065A1 (en) 1980-01-02
CH644840A5 (en) 1984-08-31
NO150482B (en) 1984-07-16
DK158836B (en) 1990-07-23
AT359484B (en) 1980-11-10
NO782756L (en) 1979-02-16
DE2835661A1 (en) 1979-03-01
IL55218A (en) 1983-03-31
NL188981C (en) 1992-12-01
NO148777B (en) 1983-09-05
GR74415B (en) 1984-06-28
GB2004293B (en) 1982-06-23
PL122586B1 (en) 1982-08-31
AR225884A1 (en) 1982-05-14
NZ187989A (en) 1981-07-13
NL7808475A (en) 1979-02-19
GB2004293A (en) 1979-03-28
NO148777C (en) 1984-01-25
SE7807987L (en) 1979-02-16
AU3877678A (en) 1980-02-14
PT68420A (en) 1978-09-01
ATA590678A (en) 1980-04-15
SE445996B (en) 1986-08-04
FI70882B (en) 1986-07-18
DK358678A (en) 1979-02-16
NO150482C (en) 1984-10-24
DE2835661C2 (en) 1991-08-22
JPH0217534B2 (en) 1990-04-20
BE869688A (en) 1979-02-12

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