FR2340932A1 - Derives de proline et composes apparentes, utiles pour reduire la tension sanguine - Google Patents
Derives de proline et composes apparentes, utiles pour reduire la tension sanguineInfo
- Publication number
- FR2340932A1 FR2340932A1 FR7704122A FR7704122A FR2340932A1 FR 2340932 A1 FR2340932 A1 FR 2340932A1 FR 7704122 A FR7704122 A FR 7704122A FR 7704122 A FR7704122 A FR 7704122A FR 2340932 A1 FR2340932 A1 FR 2340932A1
- Authority
- FR
- France
- Prior art keywords
- compounds useful
- related compounds
- reducing blood
- proline derivatives
- blood tension
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 150000003147 proline derivatives Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
- C07C53/19—Acids containing three or more carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/657,792 US4046889A (en) | 1976-02-13 | 1976-02-13 | Azetidine-2-carboxylic acid derivatives |
| US69843276A | 1976-06-21 | 1976-06-21 | |
| US05/751,851 US4105776A (en) | 1976-06-21 | 1976-12-22 | Proline derivatives and related compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2340932A1 true FR2340932A1 (fr) | 1977-09-09 |
| FR2340932B1 FR2340932B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1981-02-06 |
Family
ID=27417986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7704122A Granted FR2340932A1 (fr) | 1976-02-13 | 1977-02-14 | Derives de proline et composes apparentes, utiles pour reduire la tension sanguine |
Country Status (31)
Cited By (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2372817A1 (fr) * | 1976-12-03 | 1978-06-30 | Squibb & Sons Inc | Derives d'acides thiazolidinecarboxyliques et d'acides apparentes, utiles comme agents anti-hypertension |
| FR2377374A1 (fr) * | 1977-01-17 | 1978-08-11 | Squibb & Sons Inc | Derives acyles d'amino-acides et leur utilisation comme medicaments |
| FR2412537A1 (fr) * | 1977-12-22 | 1979-07-20 | Science Union & Cie | Nouveaux thiobutyramides substitues, leurs procedes d'obtention et leur application pharmaceutique |
| FR2413089A1 (fr) * | 1977-12-27 | 1979-07-27 | Squibb & Sons Inc | Composition de traitement de l'hypertension |
| FR2417500A1 (fr) * | 1978-02-15 | 1979-09-14 | Squibb & Sons Inc | Derives d'amino-acides cycliques dehydrogenes et leur utilisation therapeutique |
| FR2417499A1 (fr) * | 1978-02-21 | 1979-09-14 | Squibb & Sons Inc | Mercaptoacylamino-acides halogenes et leur utilisation therapeutique |
| FR2422651A1 (fr) * | 1978-04-14 | 1979-11-09 | Squibb & Sons Inc | Derives de pyrrolidinecarboxaldehyde et de piperidinecarboxaldehyde a usage therapeutique |
| FR2432019A1 (fr) * | 1978-07-27 | 1980-02-22 | Squibb & Sons Inc | Thiopropanoylamino-acides et leur utilisation therapeutique |
| FR2443460A1 (fr) * | 1978-12-08 | 1980-07-04 | Squibb & Sons Inc | Derives mercaptoacyles d'acides 4,5-dihydro-1h-pyrrole-2-carboxyliques et d'acides 1,4,5,6-tetrahydropyridine-2-carboxyliques, utiles comme agents hypotenseurs |
| FR2445324A1 (fr) * | 1978-12-30 | 1980-07-25 | Santen Pharmaceutical Co Ltd | Nouveaux derives disulfures contenant un cycle pyrrolidine ou thiazolidine utiles comme antihypertenseurs et pour prevenir et traiter les complications du diabete et procedes pour leur preparation |
| FR2446281A1 (fr) * | 1979-01-15 | 1980-08-08 | Squibb & Sons Inc | Carbamates de mercaptoacyl hydroxy prolines, a action antihypertensive |
| FR2450824A1 (fr) * | 1979-03-08 | 1980-10-03 | Squibb & Sons Inc | Nouveaux derives d'acides 1-(o-mercaptoacyl)-5-pyrazolidinone-3-carboxyliques, utiles notamment comme agents hypotenseurs |
| FR2468589A1 (fr) * | 1979-05-18 | 1981-05-08 | Squibb & Sons Inc | Derives aminoacyles de mercaptoacyl amino-acides, a action antihypertensive |
| FR2471975A1 (fr) * | 1979-12-13 | 1981-06-26 | Kanegafuchi Chemical Ind | Procede pour la preparation de n-mercaptoalcanoylaminoacides optiquement actifs |
| EP0031104A1 (en) * | 1979-12-13 | 1981-07-01 | Santen Pharmaceutical Co., Ltd. | Thiazolidine compounds, processes for their preparation and pharmaceutical compositions containing them |
| FR2473517A1 (fr) * | 1979-12-10 | 1981-07-17 | Squibb & Sons Inc | Derives d'acide carbothioique de mercaptoacyl amino acides a action anti-hypertensive et leur procede de preparation |
| FR2478632A1 (fr) * | 1980-03-21 | 1981-09-25 | Squibb & Sons Inc | Derives mercaptoacyles de la proline et de l'acide pipecolique a fonction cetonique, a action anti-hypertensive |
| FR2567881A1 (fr) * | 1984-07-23 | 1986-01-24 | Boryung Pharm | Procede pour la production d'un derive de pyrrolidine |
| FR2574792A1 (fr) * | 1984-12-19 | 1986-06-20 | Boryung Pharm | Procede pour la preparation de derives de pyrrolidine |
| FR2577222A1 (fr) * | 1985-02-11 | 1986-08-14 | Boryung Pharm | Procede pour la preparation de l'acide 1-(3-mercapto-25-methylpropionyl)-pyrrolidine-(25)-carboxylique |
| EP0427435A1 (en) * | 1989-11-06 | 1991-05-15 | E.R. Squibb & Sons, Inc. | Process for direct isolation of captopril |
| WO1994004129A3 (de) * | 1992-08-26 | 1994-05-26 | Beiersdorf Ag | Kosmetische und dermatologische lichtschutzformulierungen mit einem gehalt an thiolen und/oder thiolderivaten |
| WO1994004128A3 (de) * | 1992-08-26 | 1994-07-07 | Beiersdorf Ag | Verwendung von radikalfängern als immunmodulierende agentien in kosmetischen und dermatologischen zubereitungen |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4053651A (en) | 1976-05-10 | 1977-10-11 | E. R. Squibb & Sons, Inc. | Compounds and method for alleviating angiotensin related hypertension |
| JPS559058A (en) * | 1978-07-06 | 1980-01-22 | Dainippon Pharmaceut Co Ltd | 1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative |
| CA1144930A (en) * | 1978-08-11 | 1983-04-19 | Miguel A. Ondetti | Mercaptoacyl derivatives of substituted prolines |
| NZ190995A (en) * | 1978-09-05 | 1982-03-09 | American Cyanamid Co | Substituted omega propionyl or butyryl l-prolines and pharmaceutical compositions |
| NL7809121A (nl) * | 1978-09-07 | 1980-03-11 | Oce Andeno B V Grubbenvorsterw | Optisch aktieve derivaten van mercapto-isoboterzuur. |
| NL7809120A (nl) * | 1978-09-07 | 1980-03-11 | Oce Andeno B V Grubbenvorsterw | Werkwijze voor de bereiding van proline-derivaten. |
| US4690937A (en) * | 1979-08-14 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
| ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
| GR73585B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1978-09-11 | 1984-03-26 | Univ Miami | |
| JPS5540622A (en) * | 1978-09-14 | 1980-03-22 | Santen Pharmaceut Co Ltd | Hypotensive agent |
| US4483861A (en) * | 1978-10-31 | 1984-11-20 | Santen Pharmaceutical Co., Ltd. | Antihypertensive sulfur-containing compounds |
| US4410542A (en) | 1978-12-30 | 1983-10-18 | Santen Pharmaceutical Co., Ltd. | Disulfide compounds |
| US4461896A (en) * | 1979-02-07 | 1984-07-24 | Norwich Eaton Pharmaceuticals, Inc. | 1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids |
| US4234489A (en) * | 1979-06-25 | 1980-11-18 | E. R. Squibb & Sons, Inc. | Pyroglutamic acid derivatives and analogs |
| JPS5629403U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1979-08-13 | 1981-03-20 | ||
| DE2937779A1 (de) * | 1979-09-19 | 1981-04-09 | Hoechst Ag, 6000 Frankfurt | Aminosaeurederivate und verfahren zu ihrer herstellung |
| US4692458A (en) * | 1980-03-05 | 1987-09-08 | University Of Miami | Anti-hypertensive agents |
| DE3011239A1 (de) * | 1980-03-22 | 1981-10-01 | C.H. Boehringer Sohn, 6507 Ingelheim | Substituierte alkylthioacylaminosaeuren, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen |
| SE8203245L (sv) * | 1981-05-27 | 1982-11-28 | Crc Ricerca Chim | Forfarande for enantioselektiv framstellning av n-substituerade prolinderivat |
| JPH06740B2 (ja) * | 1984-08-16 | 1994-01-05 | 三菱レイヨン株式会社 | 光学活性カルボン酸アミドの製造法 |
| HU196369B (en) * | 1984-10-18 | 1988-11-28 | Egyt Gyogyszervegyeszeti Gyar | New process for producing n-acylized l-prolin derivatives |
| AT395012B (de) * | 1986-06-27 | 1992-08-25 | Richter Gedeon Vegyeszet | Verfahren zur herstellung von n-(1(s)|thoxycarbonyl-3-phenyl-propyl)-(s)-alanyl-(s)prolin und von dessen saeureadditionssalzen |
| JP2863534B2 (ja) * | 1988-10-24 | 1999-03-03 | マリオン ラボラトリーズ，インコーポレイティド | 医薬組成物 |
| IT1266570B1 (it) * | 1993-07-30 | 1997-01-09 | Zambon Spa | Derivati della propanammide n-eteroaril sostituiti utili nel trattamento delle malattie cardiovascolari |
| US7056935B2 (en) | 1995-06-07 | 2006-06-06 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
| GB9704522D0 (en) * | 1997-03-05 | 1997-04-23 | Smithkline Beecham Plc | Compounds |
| ATE224366T1 (de) | 1997-10-31 | 2002-10-15 | Hoffmann La Roche | D-prolinderivate |
| MXPA04001074A (es) * | 2001-08-07 | 2004-07-08 | Sunesis Pharmaceuticals Inc | Ligandos de bisulfuro y tiosulfonato y colecciones que comprenden estos ligandos. |
| CN100361971C (zh) * | 2005-09-19 | 2008-01-16 | 华中师范大学 | 催化活性可调的双官能团l-脯氨酸衍生物及制备 |
| MX2011001887A (es) | 2008-08-22 | 2011-04-04 | Baxter Int | Derivados de bencil carbonato polimericos. |
| JP6189937B2 (ja) | 2012-04-27 | 2017-08-30 | ダウ アグロサイエンシィズ エルエルシー | 農薬組成物およびそれらに関する方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA946836A (en) * | 1970-03-18 | 1974-05-07 | Miguel A. Ondetti | Enzyme inhibitor |
-
1977
- 1977-01-14 AU AU21347/77A patent/AU509899B2/en not_active Expired
- 1977-01-19 NZ NZ183130A patent/NZ183130A/xx unknown
- 1977-01-20 IL IL51297A patent/IL51297A/xx unknown
- 1977-01-21 CA CA270,184A patent/CA1101864A/en not_active Expired
- 1977-01-27 PH PH19390A patent/PH12970A/en unknown
- 1977-01-31 DE DE2759862A patent/DE2759862C2/de not_active Expired
- 1977-01-31 DE DE2703828A patent/DE2703828C2/de not_active Expired
- 1977-02-08 YU YU331/77A patent/YU40664B/xx unknown
- 1977-02-08 GR GR52745A patent/GR69811B/el unknown
- 1977-02-09 RO RO7789327A patent/RO69941A/ro unknown
- 1977-02-10 ES ES455803A patent/ES455803A1/es not_active Expired
- 1977-02-10 FI FI770437A patent/FI66596C/fi not_active IP Right Cessation
- 1977-02-11 NO NO770464A patent/NO146985C/no unknown
- 1977-02-11 HU HU77SU939A patent/HU181965B/hu unknown
- 1977-02-11 SE SE7701561A patent/SE423812B/xx not_active IP Right Cessation
- 1977-02-11 BG BG062893A patent/BG37074A3/xx unknown
- 1977-02-11 DD DD77197339A patent/DD129442B3/de unknown
- 1977-02-11 DK DK059677A patent/DK157487C/da active
- 1977-02-11 CH CH170377A patent/CH622503A5/fr not_active IP Right Cessation
- 1977-02-11 IT IT48008/77A patent/IT1062293B/it active Protection Beyond IP Right Term
- 1977-02-11 BG BG035398A patent/BG37375A3/xx unknown
- 1977-02-11 AR AR266525A patent/AR222445A1/es active
- 1977-02-11 SU SU772450455A patent/SU747422A3/ru active
- 1977-02-11 IE IE305/77A patent/IE44707B1/en not_active IP Right Cessation
- 1977-02-11 NL NLAANVRAGE7701457,A patent/NL168509C/xx not_active IP Right Cessation
- 1977-02-11 BG BG062894A patent/BG37075A3/xx unknown
- 1977-02-12 JP JP52014542A patent/JPS604815B2/ja not_active Expired
- 1977-02-12 PL PL1977195965A patent/PL118161B1/pl not_active IP Right Cessation
- 1977-02-13 GB GB4088/77A patent/GB1576161A/en not_active Expired
- 1977-02-14 AT AT0098977A patent/AT365569B/de not_active IP Right Cessation
- 1977-02-14 FR FR7704122A patent/FR2340932A1/fr active Granted
- 1977-10-31 AR AR269793A patent/AR222783A1/es active
- 1977-10-31 AR AR269794A patent/AR214649A1/es active
-
1978
- 1978-02-16 ES ES467050A patent/ES467050A1/es not_active Expired
- 1978-02-16 ES ES467052A patent/ES467052A1/es not_active Expired
- 1978-02-16 ES ES467053A patent/ES467053A1/es not_active Expired
- 1978-05-16 ES ES467051A patent/ES467051A1/es not_active Expired
-
1979
- 1979-09-11 AR AR278014A patent/AR226290A1/es active
-
1980
- 1980-02-21 CH CH141080A patent/CH624932A5/fr not_active IP Right Cessation
- 1980-02-21 CH CH140980A patent/CH624931A5/fr not_active IP Right Cessation
-
1981
- 1981-05-14 HK HK202/81A patent/HK20281A/xx unknown
- 1981-06-18 KE KE3136A patent/KE3136A/xx unknown
- 1981-08-03 SE SE8104660A patent/SE426697B/sv not_active IP Right Cessation
-
1982
- 1982-12-30 MY MY75/82A patent/MY8200075A/xx unknown
-
1987
- 1987-09-30 MY MYPI87002538A patent/MY102705A/en unknown
Cited By (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2372817A1 (fr) * | 1976-12-03 | 1978-06-30 | Squibb & Sons Inc | Derives d'acides thiazolidinecarboxyliques et d'acides apparentes, utiles comme agents anti-hypertension |
| FR2377374A1 (fr) * | 1977-01-17 | 1978-08-11 | Squibb & Sons Inc | Derives acyles d'amino-acides et leur utilisation comme medicaments |
| FR2412537A1 (fr) * | 1977-12-22 | 1979-07-20 | Science Union & Cie | Nouveaux thiobutyramides substitues, leurs procedes d'obtention et leur application pharmaceutique |
| FR2413089A1 (fr) * | 1977-12-27 | 1979-07-27 | Squibb & Sons Inc | Composition de traitement de l'hypertension |
| FR2417500A1 (fr) * | 1978-02-15 | 1979-09-14 | Squibb & Sons Inc | Derives d'amino-acides cycliques dehydrogenes et leur utilisation therapeutique |
| FR2417499A1 (fr) * | 1978-02-21 | 1979-09-14 | Squibb & Sons Inc | Mercaptoacylamino-acides halogenes et leur utilisation therapeutique |
| FR2422651A1 (fr) * | 1978-04-14 | 1979-11-09 | Squibb & Sons Inc | Derives de pyrrolidinecarboxaldehyde et de piperidinecarboxaldehyde a usage therapeutique |
| FR2432019A1 (fr) * | 1978-07-27 | 1980-02-22 | Squibb & Sons Inc | Thiopropanoylamino-acides et leur utilisation therapeutique |
| FR2443460A1 (fr) * | 1978-12-08 | 1980-07-04 | Squibb & Sons Inc | Derives mercaptoacyles d'acides 4,5-dihydro-1h-pyrrole-2-carboxyliques et d'acides 1,4,5,6-tetrahydropyridine-2-carboxyliques, utiles comme agents hypotenseurs |
| FR2445324A1 (fr) * | 1978-12-30 | 1980-07-25 | Santen Pharmaceutical Co Ltd | Nouveaux derives disulfures contenant un cycle pyrrolidine ou thiazolidine utiles comme antihypertenseurs et pour prevenir et traiter les complications du diabete et procedes pour leur preparation |
| FR2446281A1 (fr) * | 1979-01-15 | 1980-08-08 | Squibb & Sons Inc | Carbamates de mercaptoacyl hydroxy prolines, a action antihypertensive |
| FR2450824A1 (fr) * | 1979-03-08 | 1980-10-03 | Squibb & Sons Inc | Nouveaux derives d'acides 1-(o-mercaptoacyl)-5-pyrazolidinone-3-carboxyliques, utiles notamment comme agents hypotenseurs |
| FR2468589A1 (fr) * | 1979-05-18 | 1981-05-08 | Squibb & Sons Inc | Derives aminoacyles de mercaptoacyl amino-acides, a action antihypertensive |
| FR2473517A1 (fr) * | 1979-12-10 | 1981-07-17 | Squibb & Sons Inc | Derives d'acide carbothioique de mercaptoacyl amino acides a action anti-hypertensive et leur procede de preparation |
| FR2471975A1 (fr) * | 1979-12-13 | 1981-06-26 | Kanegafuchi Chemical Ind | Procede pour la preparation de n-mercaptoalcanoylaminoacides optiquement actifs |
| EP0031104A1 (en) * | 1979-12-13 | 1981-07-01 | Santen Pharmaceutical Co., Ltd. | Thiazolidine compounds, processes for their preparation and pharmaceutical compositions containing them |
| FR2478632A1 (fr) * | 1980-03-21 | 1981-09-25 | Squibb & Sons Inc | Derives mercaptoacyles de la proline et de l'acide pipecolique a fonction cetonique, a action anti-hypertensive |
| FR2567881A1 (fr) * | 1984-07-23 | 1986-01-24 | Boryung Pharm | Procede pour la production d'un derive de pyrrolidine |
| FR2574792A1 (fr) * | 1984-12-19 | 1986-06-20 | Boryung Pharm | Procede pour la preparation de derives de pyrrolidine |
| FR2577222A1 (fr) * | 1985-02-11 | 1986-08-14 | Boryung Pharm | Procede pour la preparation de l'acide 1-(3-mercapto-25-methylpropionyl)-pyrrolidine-(25)-carboxylique |
| EP0427435A1 (en) * | 1989-11-06 | 1991-05-15 | E.R. Squibb & Sons, Inc. | Process for direct isolation of captopril |
| WO1994004129A3 (de) * | 1992-08-26 | 1994-05-26 | Beiersdorf Ag | Kosmetische und dermatologische lichtschutzformulierungen mit einem gehalt an thiolen und/oder thiolderivaten |
| WO1994004128A3 (de) * | 1992-08-26 | 1994-07-07 | Beiersdorf Ag | Verwendung von radikalfängern als immunmodulierende agentien in kosmetischen und dermatologischen zubereitungen |
| AU690075B2 (en) * | 1992-08-26 | 1998-04-23 | Beiersdorf Aktiengesellschaft | Use of radical catchers as immunomodulating agents in cosmetic and dermatological compositions |
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