FR2450824A1 - Nouveaux derives d'acides 1-(o-mercaptoacyl)-5-pyrazolidinone-3-carboxyliques, utiles notamment comme agents hypotenseurs - Google Patents
Nouveaux derives d'acides 1-(o-mercaptoacyl)-5-pyrazolidinone-3-carboxyliques, utiles notamment comme agents hypotenseursInfo
- Publication number
- FR2450824A1 FR2450824A1 FR8005216A FR8005216A FR2450824A1 FR 2450824 A1 FR2450824 A1 FR 2450824A1 FR 8005216 A FR8005216 A FR 8005216A FR 8005216 A FR8005216 A FR 8005216A FR 2450824 A1 FR2450824 A1 FR 2450824A1
- Authority
- FR
- France
- Prior art keywords
- mercaptoacyl
- pyrazolidinone
- carboxylics
- useful
- acid derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000001953 Hypotension Diseases 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 230000036543 hypotension Effects 0.000 title 1
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical group [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D231/08—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen or sulfur atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LES COMPOSES DE L'INVENTION SONT DES DERIVES D'ACIDES 1- (MERCAPTOACYL)-5-PYRAZOLIDINONE-3-CARBOXYLIQUES, DE FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE R EST UN ATOME D'HYDROGENE OU
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/018,547 US4220791A (en) | 1979-03-08 | 1979-03-08 | Mercaptoacylpyrazolidinone carboxylic acid derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2450824A1 true FR2450824A1 (fr) | 1980-10-03 |
FR2450824B1 FR2450824B1 (fr) | 1983-01-14 |
Family
ID=21788495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8005216A Granted FR2450824A1 (fr) | 1979-03-08 | 1980-03-07 | Nouveaux derives d'acides 1-(o-mercaptoacyl)-5-pyrazolidinone-3-carboxyliques, utiles notamment comme agents hypotenseurs |
Country Status (7)
Country | Link |
---|---|
US (1) | US4220791A (fr) |
JP (1) | JPS55127374A (fr) |
CA (1) | CA1137498A (fr) |
DE (1) | DE3008903A1 (fr) |
FR (1) | FR2450824A1 (fr) |
GB (1) | GB2048849B (fr) |
IT (1) | IT1127383B (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
US4692458A (en) * | 1980-03-05 | 1987-09-08 | University Of Miami | Anti-hypertensive agents |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3153654A (en) * | 1961-05-31 | 1964-10-20 | Ilford Ltd | 3-pyrazolidinone carboxylic acid derivatives |
FR2340932A1 (fr) * | 1976-02-13 | 1977-09-09 | Squibb & Sons Inc | Derives de proline et composes apparentes, utiles pour reduire la tension sanguine |
US4095024A (en) * | 1975-01-31 | 1978-06-13 | Imperial Chemical Industries Limited | Process for the manufacture of 1-aryl-3-carboxypyrazolid-5-ones |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
ZA777062B (en) | 1976-12-03 | 1979-02-28 | Squibb & Sons Inc | Derivatives of thiazolidinecarboxylic acids and related acids |
US4129566A (en) * | 1978-02-15 | 1978-12-12 | E. R. Squibb & Sons, Inc. | Derivatives of dehydrocyclicimino acids |
-
1979
- 1979-03-08 US US06/018,547 patent/US4220791A/en not_active Expired - Lifetime
-
1980
- 1980-02-20 CA CA000346091A patent/CA1137498A/fr not_active Expired
- 1980-03-03 IT IT48061/80A patent/IT1127383B/it active
- 1980-03-07 FR FR8005216A patent/FR2450824A1/fr active Granted
- 1980-03-07 GB GB8007913A patent/GB2048849B/en not_active Expired
- 1980-03-07 DE DE19803008903 patent/DE3008903A1/de not_active Withdrawn
- 1980-03-08 JP JP2971380A patent/JPS55127374A/ja active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3153654A (en) * | 1961-05-31 | 1964-10-20 | Ilford Ltd | 3-pyrazolidinone carboxylic acid derivatives |
US4095024A (en) * | 1975-01-31 | 1978-06-13 | Imperial Chemical Industries Limited | Process for the manufacture of 1-aryl-3-carboxypyrazolid-5-ones |
FR2340932A1 (fr) * | 1976-02-13 | 1977-09-09 | Squibb & Sons Inc | Derives de proline et composes apparentes, utiles pour reduire la tension sanguine |
Also Published As
Publication number | Publication date |
---|---|
DE3008903A1 (de) | 1980-09-18 |
GB2048849B (en) | 1983-05-25 |
IT1127383B (it) | 1986-05-21 |
US4220791A (en) | 1980-09-02 |
JPS55127374A (en) | 1980-10-02 |
IT8048061A0 (it) | 1980-03-03 |
CA1137498A (fr) | 1982-12-14 |
GB2048849A (en) | 1980-12-17 |
FR2450824B1 (fr) | 1983-01-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |