FR2422651A1 - Derives de pyrrolidinecarboxaldehyde et de piperidinecarboxaldehyde a usage therapeutique - Google Patents
Derives de pyrrolidinecarboxaldehyde et de piperidinecarboxaldehyde a usage therapeutiqueInfo
- Publication number
- FR2422651A1 FR2422651A1 FR7909362A FR7909362A FR2422651A1 FR 2422651 A1 FR2422651 A1 FR 2422651A1 FR 7909362 A FR7909362 A FR 7909362A FR 7909362 A FR7909362 A FR 7909362A FR 2422651 A1 FR2422651 A1 FR 2422651A1
- Authority
- FR
- France
- Prior art keywords
- pyrrolidinecarboxaldehyde
- piperidinecarboxaldehyde
- derivatives
- therapeutic use
- therapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Composés de formule :
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/896,420 US4206122A (en) | 1978-04-14 | 1978-04-14 | Derivatives of pyrrolidinecarboxaldehyde and piperidinecarboxaldehyde and intermediates therefor |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2422651A1 true FR2422651A1 (fr) | 1979-11-09 |
FR2422651B1 FR2422651B1 (fr) | 1982-05-21 |
Family
ID=25406179
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7909362A Granted FR2422651A1 (fr) | 1978-04-14 | 1979-04-12 | Derives de pyrrolidinecarboxaldehyde et de piperidinecarboxaldehyde a usage therapeutique |
Country Status (27)
Country | Link |
---|---|
US (1) | US4206122A (fr) |
JP (1) | JPS54145662A (fr) |
AT (1) | AT373237B (fr) |
AU (1) | AU528337B2 (fr) |
BE (1) | BE875592A (fr) |
CA (1) | CA1124726A (fr) |
CH (1) | CH638183A5 (fr) |
DD (1) | DD142876A5 (fr) |
DE (1) | DE2914793A1 (fr) |
DK (1) | DK153579A (fr) |
ES (1) | ES479444A1 (fr) |
FR (1) | FR2422651A1 (fr) |
GB (1) | GB2020648B (fr) |
HU (1) | HU178357B (fr) |
IE (1) | IE48497B1 (fr) |
IL (1) | IL57071A (fr) |
IT (1) | IT1120407B (fr) |
LU (1) | LU81150A1 (fr) |
NL (1) | NL7902852A (fr) |
NO (1) | NO791236L (fr) |
NZ (1) | NZ190090A (fr) |
PH (1) | PH14438A (fr) |
PL (1) | PL214887A1 (fr) |
PT (1) | PT69483A (fr) |
SU (1) | SU791227A3 (fr) |
YU (1) | YU85979A (fr) |
ZA (1) | ZA791584B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
DD154444A3 (de) * | 1980-07-11 | 1982-03-24 | Roland Ohme | Verfahren zur herstellung neuer sulfobetaine |
US4626545A (en) * | 1984-08-27 | 1986-12-02 | Merck & Co., Inc. | Amino acid derivatives as enzyme inhibitors |
JPH0764834B2 (ja) * | 1985-11-29 | 1995-07-12 | サントリー株式会社 | プロリルエンドペプチダーゼ阻害活性を有する新規ピロリジンアミド誘導体およびその製法並びに用途 |
JP2691442B2 (ja) * | 1989-02-20 | 1997-12-17 | 株式会社ヤクルト本社 | 新規なプロリン誘導体 |
JP3974656B2 (ja) * | 1995-11-16 | 2007-09-12 | ジー.ディー.サール アンド カンパニー | N−保護/n−置換−ベータ−アミノヒドロキシスルホネート |
JP5041219B2 (ja) * | 2006-07-14 | 2012-10-03 | ナガセケムテックス株式会社 | 光学活性ビスオキサゾリン−銅錯体を不斉触媒とするn−保護アミノアルコール化合物の不斉エステル化反応 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2340932A1 (fr) * | 1976-02-13 | 1977-09-09 | Squibb & Sons Inc | Derives de proline et composes apparentes, utiles pour reduire la tension sanguine |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
-
1978
- 1978-04-14 US US05/896,420 patent/US4206122A/en not_active Expired - Lifetime
-
1979
- 1979-03-28 CA CA324,321A patent/CA1124726A/fr not_active Expired
- 1979-03-30 AU AU45667/79A patent/AU528337B2/en not_active Ceased
- 1979-04-02 NZ NZ190090A patent/NZ190090A/xx unknown
- 1979-04-03 ZA ZA791584A patent/ZA791584B/xx unknown
- 1979-04-09 GB GB7912367A patent/GB2020648B/en not_active Expired
- 1979-04-09 ES ES479444A patent/ES479444A1/es not_active Expired
- 1979-04-10 PH PH22366A patent/PH14438A/en unknown
- 1979-04-11 YU YU00859/79A patent/YU85979A/xx unknown
- 1979-04-11 NL NL7902852A patent/NL7902852A/xx not_active Application Discontinuation
- 1979-04-11 DK DK153579A patent/DK153579A/da not_active IP Right Cessation
- 1979-04-11 DE DE19792914793 patent/DE2914793A1/de not_active Withdrawn
- 1979-04-11 CH CH345379A patent/CH638183A5/fr not_active IP Right Cessation
- 1979-04-11 NO NO791236A patent/NO791236L/no unknown
- 1979-04-12 DD DD79212198A patent/DD142876A5/de unknown
- 1979-04-12 FR FR7909362A patent/FR2422651A1/fr active Granted
- 1979-04-12 PT PT69483A patent/PT69483A/pt unknown
- 1979-04-13 JP JP4595979A patent/JPS54145662A/ja active Pending
- 1979-04-13 SU SU792753363A patent/SU791227A3/ru active
- 1979-04-13 IT IT48727/79A patent/IT1120407B/it active
- 1979-04-13 LU LU81150A patent/LU81150A1/fr unknown
- 1979-04-13 BE BE0/194617A patent/BE875592A/fr not_active IP Right Cessation
- 1979-04-13 PL PL21488779A patent/PL214887A1/xx unknown
- 1979-04-13 HU HU79SU1014A patent/HU178357B/hu not_active IP Right Cessation
- 1979-04-15 IL IL57071A patent/IL57071A/xx unknown
- 1979-04-17 AT AT0286579A patent/AT373237B/de not_active IP Right Cessation
- 1979-08-08 IE IE771/79A patent/IE48497B1/en not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2340932A1 (fr) * | 1976-02-13 | 1977-09-09 | Squibb & Sons Inc | Derives de proline et composes apparentes, utiles pour reduire la tension sanguine |
Also Published As
Publication number | Publication date |
---|---|
NO791236L (no) | 1979-10-16 |
IL57071A0 (en) | 1979-07-25 |
CA1124726A (fr) | 1982-06-01 |
BE875592A (fr) | 1979-10-15 |
US4206122A (en) | 1980-06-03 |
HU178357B (en) | 1982-04-28 |
YU85979A (en) | 1983-02-28 |
PT69483A (en) | 1979-05-01 |
ZA791584B (en) | 1980-08-27 |
IT7948727A0 (it) | 1979-04-13 |
JPS54145662A (en) | 1979-11-14 |
DK153579A (da) | 1979-10-15 |
ATA286579A (de) | 1983-05-15 |
IL57071A (en) | 1982-04-30 |
CH638183A5 (fr) | 1983-09-15 |
NZ190090A (en) | 1982-03-09 |
AU528337B2 (en) | 1983-04-28 |
GB2020648B (en) | 1982-07-21 |
PH14438A (en) | 1981-07-16 |
AU4566779A (en) | 1979-10-18 |
LU81150A1 (fr) | 1979-07-20 |
AT373237B (de) | 1983-12-27 |
FR2422651B1 (fr) | 1982-05-21 |
NL7902852A (nl) | 1979-10-16 |
SU791227A3 (ru) | 1980-12-23 |
ES479444A1 (es) | 1979-11-16 |
GB2020648A (en) | 1979-11-21 |
DE2914793A1 (de) | 1979-10-18 |
PL214887A1 (fr) | 1980-01-28 |
IT1120407B (it) | 1986-03-26 |
IE48497B1 (en) | 1985-02-06 |
IE790771L (en) | 1979-10-14 |
DD142876A5 (de) | 1980-07-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |