DK153579A - Fremgangsmaade til fremstilling af derivater af pyrrolidincarboxaldehyd og piperidincarboxaldehyd samt mellemprodukter hertil - Google Patents

Fremgangsmaade til fremstilling af derivater af pyrrolidincarboxaldehyd og piperidincarboxaldehyd samt mellemprodukter hertil

Info

Publication number
DK153579A
DK153579A DK153579A DK153579A DK153579A DK 153579 A DK153579 A DK 153579A DK 153579 A DK153579 A DK 153579A DK 153579 A DK153579 A DK 153579A DK 153579 A DK153579 A DK 153579A
Authority
DK
Denmark
Prior art keywords
piperidincarboxaldehyde
carboxaldehyde
pyrrolidin
derivatives
procedure
Prior art date
Application number
DK153579A
Other languages
English (en)
Inventor
S I Natarajan
M A Ondetti
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of DK153579A publication Critical patent/DK153579A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/42Oxygen atoms attached in position 3 or 5
DK153579A 1978-04-14 1979-04-11 Fremgangsmaade til fremstilling af derivater af pyrrolidincarboxaldehyd og piperidincarboxaldehyd samt mellemprodukter hertil DK153579A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/896,420 US4206122A (en) 1978-04-14 1978-04-14 Derivatives of pyrrolidinecarboxaldehyde and piperidinecarboxaldehyde and intermediates therefor

Publications (1)

Publication Number Publication Date
DK153579A true DK153579A (da) 1979-10-15

Family

ID=25406179

Family Applications (1)

Application Number Title Priority Date Filing Date
DK153579A DK153579A (da) 1978-04-14 1979-04-11 Fremgangsmaade til fremstilling af derivater af pyrrolidincarboxaldehyd og piperidincarboxaldehyd samt mellemprodukter hertil

Country Status (27)

Country Link
US (1) US4206122A (da)
JP (1) JPS54145662A (da)
AT (1) AT373237B (da)
AU (1) AU528337B2 (da)
BE (1) BE875592A (da)
CA (1) CA1124726A (da)
CH (1) CH638183A5 (da)
DD (1) DD142876A5 (da)
DE (1) DE2914793A1 (da)
DK (1) DK153579A (da)
ES (1) ES479444A1 (da)
FR (1) FR2422651A1 (da)
GB (1) GB2020648B (da)
HU (1) HU178357B (da)
IE (1) IE48497B1 (da)
IL (1) IL57071A (da)
IT (1) IT1120407B (da)
LU (1) LU81150A1 (da)
NL (1) NL7902852A (da)
NO (1) NO791236L (da)
NZ (1) NZ190090A (da)
PH (1) PH14438A (da)
PL (1) PL214887A1 (da)
PT (1) PT69483A (da)
SU (1) SU791227A3 (da)
YU (1) YU85979A (da)
ZA (1) ZA791584B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA794723B (en) * 1978-09-11 1980-08-27 Univ Miami Anti-hypertensive agents
DD154444A3 (de) * 1980-07-11 1982-03-24 Roland Ohme Verfahren zur herstellung neuer sulfobetaine
US4626545A (en) * 1984-08-27 1986-12-02 Merck & Co., Inc. Amino acid derivatives as enzyme inhibitors
JPH0764834B2 (ja) * 1985-11-29 1995-07-12 サントリー株式会社 プロリルエンドペプチダーゼ阻害活性を有する新規ピロリジンアミド誘導体およびその製法並びに用途
JP2691442B2 (ja) * 1989-02-20 1997-12-17 株式会社ヤクルト本社 新規なプロリン誘導体
PT861233E (pt) * 1995-11-16 2000-09-29 Searle & Co Beta-amino-hidroxissulfonatos n-protegidos/n-substituidos
JP5041219B2 (ja) * 2006-07-14 2012-10-03 ナガセケムテックス株式会社 光学活性ビスオキサゾリン−銅錯体を不斉触媒とするn−保護アミノアルコール化合物の不斉エステル化反応

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives

Also Published As

Publication number Publication date
NO791236L (no) 1979-10-16
BE875592A (fr) 1979-10-15
NZ190090A (en) 1982-03-09
YU85979A (en) 1983-02-28
IE48497B1 (en) 1985-02-06
AU528337B2 (en) 1983-04-28
ES479444A1 (es) 1979-11-16
IL57071A (en) 1982-04-30
NL7902852A (nl) 1979-10-16
IE790771L (en) 1979-10-14
ZA791584B (en) 1980-08-27
PH14438A (en) 1981-07-16
US4206122A (en) 1980-06-03
JPS54145662A (en) 1979-11-14
CA1124726A (en) 1982-06-01
GB2020648B (en) 1982-07-21
IT7948727A0 (it) 1979-04-13
AT373237B (de) 1983-12-27
PL214887A1 (da) 1980-01-28
CH638183A5 (fr) 1983-09-15
FR2422651B1 (da) 1982-05-21
AU4566779A (en) 1979-10-18
GB2020648A (en) 1979-11-21
PT69483A (en) 1979-05-01
DD142876A5 (de) 1980-07-16
IL57071A0 (en) 1979-07-25
SU791227A3 (ru) 1980-12-23
ATA286579A (de) 1983-05-15
LU81150A1 (fr) 1979-07-20
FR2422651A1 (fr) 1979-11-09
IT1120407B (it) 1986-03-26
HU178357B (en) 1982-04-28
DE2914793A1 (de) 1979-10-18

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