AT373237B - Verfahren zur herstellung von neuen pyrrolidinund piperidin-derivarten - Google Patents

Verfahren zur herstellung von neuen pyrrolidinund piperidin-derivarten

Info

Publication number
AT373237B
AT373237B AT0286579A AT286579A AT373237B AT 373237 B AT373237 B AT 373237B AT 0286579 A AT0286579 A AT 0286579A AT 286579 A AT286579 A AT 286579A AT 373237 B AT373237 B AT 373237B
Authority
AT
Austria
Prior art keywords
piperidine derivatives
producing new
new pyrrolidine
pyrrolidine
producing
Prior art date
Application number
AT0286579A
Other languages
English (en)
Other versions
ATA286579A (de
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of ATA286579A publication Critical patent/ATA286579A/de
Application granted granted Critical
Publication of AT373237B publication Critical patent/AT373237B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/42Oxygen atoms attached in position 3 or 5
AT0286579A 1978-04-14 1979-04-17 Verfahren zur herstellung von neuen pyrrolidinund piperidin-derivarten AT373237B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/896,420 US4206122A (en) 1978-04-14 1978-04-14 Derivatives of pyrrolidinecarboxaldehyde and piperidinecarboxaldehyde and intermediates therefor

Publications (2)

Publication Number Publication Date
ATA286579A ATA286579A (de) 1983-05-15
AT373237B true AT373237B (de) 1983-12-27

Family

ID=25406179

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0286579A AT373237B (de) 1978-04-14 1979-04-17 Verfahren zur herstellung von neuen pyrrolidinund piperidin-derivarten

Country Status (27)

Country Link
US (1) US4206122A (de)
JP (1) JPS54145662A (de)
AT (1) AT373237B (de)
AU (1) AU528337B2 (de)
BE (1) BE875592A (de)
CA (1) CA1124726A (de)
CH (1) CH638183A5 (de)
DD (1) DD142876A5 (de)
DE (1) DE2914793A1 (de)
DK (1) DK153579A (de)
ES (1) ES479444A1 (de)
FR (1) FR2422651A1 (de)
GB (1) GB2020648B (de)
HU (1) HU178357B (de)
IE (1) IE48497B1 (de)
IL (1) IL57071A (de)
IT (1) IT1120407B (de)
LU (1) LU81150A1 (de)
NL (1) NL7902852A (de)
NO (1) NO791236L (de)
NZ (1) NZ190090A (de)
PH (1) PH14438A (de)
PL (1) PL214887A1 (de)
PT (1) PT69483A (de)
SU (1) SU791227A3 (de)
YU (1) YU85979A (de)
ZA (1) ZA791584B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA794723B (en) * 1978-09-11 1980-08-27 Univ Miami Anti-hypertensive agents
DD154444A3 (de) * 1980-07-11 1982-03-24 Roland Ohme Verfahren zur herstellung neuer sulfobetaine
US4626545A (en) * 1984-08-27 1986-12-02 Merck & Co., Inc. Amino acid derivatives as enzyme inhibitors
JPH0764834B2 (ja) * 1985-11-29 1995-07-12 サントリー株式会社 プロリルエンドペプチダーゼ阻害活性を有する新規ピロリジンアミド誘導体およびその製法並びに用途
JP2691442B2 (ja) * 1989-02-20 1997-12-17 株式会社ヤクルト本社 新規なプロリン誘導体
PT861233E (pt) * 1995-11-16 2000-09-29 Searle & Co Beta-amino-hidroxissulfonatos n-protegidos/n-substituidos
JP5041219B2 (ja) * 2006-07-14 2012-10-03 ナガセケムテックス株式会社 光学活性ビスオキサゾリン−銅錯体を不斉触媒とするn−保護アミノアルコール化合物の不斉エステル化反応

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives

Also Published As

Publication number Publication date
NO791236L (no) 1979-10-16
BE875592A (fr) 1979-10-15
NZ190090A (en) 1982-03-09
YU85979A (en) 1983-02-28
IE48497B1 (en) 1985-02-06
AU528337B2 (en) 1983-04-28
ES479444A1 (es) 1979-11-16
IL57071A (en) 1982-04-30
NL7902852A (nl) 1979-10-16
IE790771L (en) 1979-10-14
ZA791584B (en) 1980-08-27
PH14438A (en) 1981-07-16
DK153579A (da) 1979-10-15
US4206122A (en) 1980-06-03
JPS54145662A (en) 1979-11-14
CA1124726A (en) 1982-06-01
GB2020648B (en) 1982-07-21
IT7948727A0 (it) 1979-04-13
PL214887A1 (de) 1980-01-28
CH638183A5 (fr) 1983-09-15
FR2422651B1 (de) 1982-05-21
AU4566779A (en) 1979-10-18
GB2020648A (en) 1979-11-21
PT69483A (en) 1979-05-01
DD142876A5 (de) 1980-07-16
IL57071A0 (en) 1979-07-25
SU791227A3 (ru) 1980-12-23
ATA286579A (de) 1983-05-15
LU81150A1 (fr) 1979-07-20
FR2422651A1 (fr) 1979-11-09
IT1120407B (it) 1986-03-26
HU178357B (en) 1982-04-28
DE2914793A1 (de) 1979-10-18

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELJ Ceased due to non-payment of the annual fee