AU514523B2 - Hydantoin and thio-hydantoin derivatives - Google Patents

Hydantoin and thio-hydantoin derivatives

Info

Publication number
AU514523B2
AU514523B2 AU31613/77A AU3161377A AU514523B2 AU 514523 B2 AU514523 B2 AU 514523B2 AU 31613/77 A AU31613/77 A AU 31613/77A AU 3161377 A AU3161377 A AU 3161377A AU 514523 B2 AU514523 B2 AU 514523B2
Authority
AU
Australia
Prior art keywords
hydantoin
thio
derivatives
hydantoin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU31613/77A
Other versions
AU3161377A (en
Inventor
G Wootton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB52955/76A external-priority patent/GB1598662A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of AU3161377A publication Critical patent/AU3161377A/en
Priority to AU64705/80A priority Critical patent/AU6470580A/en
Application granted granted Critical
Publication of AU514523B2 publication Critical patent/AU514523B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827—X being H
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
AU31613/77A 1976-12-18 1977-12-15 Hydantoin and thio-hydantoin derivatives Expired AU514523B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU64705/80A AU6470580A (en) 1976-12-18 1980-11-25 Ureidoazelates

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB52955/76A GB1598662A (en) 1976-12-18 1976-12-18 10,12-diazoprostaglandins
GBGB52955/76 1976-12-18
GBGB30369/77 1977-07-20
GB3036977 1977-07-20

Related Child Applications (3)

Application Number Title Priority Date Filing Date
AU64704/80A Division AU525235B2 (en) 1976-12-18 1980-11-25 Ureidoazelates
AU64703/80A Division AU526215B2 (en) 1976-12-18 1980-11-25 10-12-diaza prostaglanoin analogues
AU64705/80A Division AU6470580A (en) 1976-12-18 1980-11-25 Ureidoazelates

Publications (2)

Publication Number Publication Date
AU3161377A AU3161377A (en) 1979-06-21
AU514523B2 true AU514523B2 (en) 1981-02-12

Family

ID=26260409

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31613/77A Expired AU514523B2 (en) 1976-12-18 1977-12-15 Hydantoin and thio-hydantoin derivatives

Country Status (15)

Country Link
JP (1) JPS5382779A (en)
AT (1) AT368498B (en)
AU (1) AU514523B2 (en)
CH (1) CH639076A5 (en)
DE (1) DE2755771A1 (en)
DK (1) DK551777A (en)
ES (1) ES465176A1 (en)
FI (1) FI773812A (en)
FR (1) FR2374309A1 (en)
IL (1) IL53559A0 (en)
NL (1) NL7713971A (en)
NO (1) NO774348L (en)
NZ (1) NZ185909A (en)
PH (1) PH14398A (en)
SE (1) SE7714373L (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1602188A (en) 1977-12-01 1981-11-11 Wellcome Found Hydantoin derivatives
ZA786739B (en) * 1977-12-01 1980-07-30 Wellcome Found Hydantoin derivatives and salts thereof,their syntheses,and intermediates,and pharmaceutical formulations
DE2963795D1 (en) * 1978-01-23 1982-11-11 Beecham Group Plc Hydantoins and thiohydantoins, method for their preparation and pharmaceutical compositions containing them
EP0004723A1 (en) * 1978-03-30 1979-10-17 Beecham Group Plc Deoxyhydantoins, processes for their preparation and pharmaceutical compositions containing them
AU4778279A (en) * 1978-06-15 1979-12-20 Beecham Group Limited Prostaglandin analogues
DE2965099D1 (en) * 1978-06-15 1983-05-05 Beecham Group Plc Prostaglandin analogue triazole derivatives, processes for their preparation and a pharmaceutical composition containing them
IL57504A0 (en) * 1978-06-15 1979-10-31 Beecham Group Ltd Prostagandin analogues,their preparation and pharmaceutical compositions containing
EP0006352A1 (en) * 1978-06-15 1980-01-09 Beecham Group Plc Hydantoins and thiohydantoins, process for their preparation and pharmaceutical compositions containing them
EP0019223A1 (en) * 1979-05-09 1980-11-26 The Wellcome Foundation Limited Optically active hydantoin derivatives, their synthesis, pharmaceutical formulations containing them, and intermediates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2323193A1 (en) 1972-05-10 1973-11-22 Du Pont PYRAZOLIDINONE
FR2258376A1 (en) 1974-01-21 1975-08-18 Aries Robert 10-Aza prostaglandins - for treatment of blood pressure and gastro-intestinal disorders and in prepn for confinement
GB1524818A (en) 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins

Also Published As

Publication number Publication date
AU3161377A (en) 1979-06-21
NZ185909A (en) 1980-11-14
SE7714373L (en) 1978-06-19
DK551777A (en) 1978-06-19
AT368498B (en) 1982-10-11
PH14398A (en) 1981-06-25
NL7713971A (en) 1978-06-20
NO774348L (en) 1978-06-20
DE2755771A1 (en) 1978-06-29
FI773812A (en) 1978-06-19
ATA893777A (en) 1982-02-15
FR2374309A1 (en) 1978-07-13
CH639076A5 (en) 1983-10-31
ES465176A1 (en) 1979-01-01
FR2374309B1 (en) 1980-05-16
IL53559A0 (en) 1978-03-10
JPS5382779A (en) 1978-07-21

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