FR2205335A1 - - Google Patents

Info

Publication number
FR2205335A1
FR2205335A1 FR7339544A FR7339544A FR2205335A1 FR 2205335 A1 FR2205335 A1 FR 2205335A1 FR 7339544 A FR7339544 A FR 7339544A FR 7339544 A FR7339544 A FR 7339544A FR 2205335 A1 FR2205335 A1 FR 2205335A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7339544A
Other languages
French (fr)
Other versions
FR2205335B1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of FR2205335A1 publication Critical patent/FR2205335A1/fr
Application granted granted Critical
Publication of FR2205335B1 publication Critical patent/FR2205335B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5407Acyclic saturated phosphonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7339544A 1972-11-08 1973-11-07 Expired FR2205335B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30481372A 1972-11-08 1972-11-08

Publications (2)

Publication Number Publication Date
FR2205335A1 true FR2205335A1 (es) 1974-05-31
FR2205335B1 FR2205335B1 (es) 1978-07-13

Family

ID=23178133

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7339544A Expired FR2205335B1 (es) 1972-11-08 1973-11-07
FR7526059A Granted FR2279729A1 (fr) 1972-11-08 1975-08-22 Intermediaire de synthese de prostaglandines
FR7526060A Granted FR2283146A1 (fr) 1972-11-08 1975-08-22 Phosphonates de dialkyle

Family Applications After (2)

Application Number Title Priority Date Filing Date
FR7526059A Granted FR2279729A1 (fr) 1972-11-08 1975-08-22 Intermediaire de synthese de prostaglandines
FR7526060A Granted FR2283146A1 (fr) 1972-11-08 1975-08-22 Phosphonates de dialkyle

Country Status (29)

Country Link
JP (3) JPS5416491B2 (es)
AR (3) AR200585A1 (es)
AT (3) AT367034B (es)
AU (1) AU470375B2 (es)
BE (1) BE806995A (es)
CA (3) CA1085831A (es)
CH (1) CH597176A5 (es)
CS (3) CS182793B2 (es)
DD (4) DD118856A5 (es)
DE (1) DE2355540C2 (es)
DK (1) DK144247C (es)
ES (3) ES420325A1 (es)
FI (1) FI60389C (es)
FR (3) FR2205335B1 (es)
GB (3) GB1456514A (es)
HK (3) HK27979A (es)
HU (3) HU171819B (es)
IE (1) IE39537B1 (es)
IL (1) IL43589A (es)
IN (1) IN139384B (es)
KE (3) KE2932A (es)
MY (3) MY7900243A (es)
NL (1) NL164273C (es)
NO (3) NO147836C (es)
PH (3) PH13272A (es)
SE (4) SE448992B (es)
SU (4) SU584766A3 (es)
YU (3) YU39715B (es)
ZA (1) ZA738554B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2411178A2 (fr) * 1977-12-12 1979-07-06 Upjohn Co Analogues de prostaglandines et medicament en contenant

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
US3986764A (en) * 1975-03-31 1976-10-19 Gte Automatic Electric Laboratories Incorporated Panel for supporting a pair of elongated mating connectors and selectively locking them together
GB1506816A (en) * 1975-03-31 1978-04-12 Upjohn Co Prostaglandins
ES449162A1 (es) * 1975-06-23 1977-12-16 Syntex Inc Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.
GB1516414A (en) * 1975-08-22 1978-07-05 Ici Ltd Prostane derivatives
DK523378A (da) * 1978-01-16 1979-07-17 Pfizer Fremgangsmaade til fremstilling af n-(tetrazol-5-yl) prostaglandin-carboxamider eller salte deraf
WO1999012898A1 (en) * 1997-09-09 1999-03-18 The Procter & Gamble Company Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
EP1159266B1 (en) 1999-03-05 2004-11-03 Duke University C-16 unsaturated fp-selective prostaglandins analogs
US6894175B1 (en) 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
JP2002329615A (ja) * 2001-05-02 2002-11-15 Ohira Denshi Kk トロイダルコイル
US6476064B1 (en) * 2001-06-13 2002-11-05 Allergan, Inc. Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents
WO2006047466A2 (en) 2004-10-21 2006-05-04 Duke University Ophthamological drugs
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2137712A1 (en) * 1971-05-11 1972-12-29 Ici Ltd Novel prostanoic acid or its salt used as pharmaceutical or veterinary composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1324737A (en) * 1970-11-02 1973-07-25 Upjohn Co Prostaglandins and the preparation thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2137712A1 (en) * 1971-05-11 1972-12-29 Ici Ltd Novel prostanoic acid or its salt used as pharmaceutical or veterinary composition

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL COMMUNICATIONS, 1969, PAGES 304-305) *
J.A.C.S., VOLUME 91 1969 PAGES 5675-7 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2411178A2 (fr) * 1977-12-12 1979-07-06 Upjohn Co Analogues de prostaglandines et medicament en contenant

Also Published As

Publication number Publication date
PH13325A (en) 1980-03-13
JPS5257147A (en) 1977-05-11
NO148998B (no) 1983-10-17
YU270680A (en) 1983-04-27
KE2931A (en) 1979-03-30
NO750535L (es) 1974-05-09
AR202931A1 (es) 1975-07-31
MY7900243A (en) 1979-12-31
ES420325A1 (es) 1976-04-16
HU173507B (hu) 1979-05-28
SU893130A3 (ru) 1981-12-23
DD109212A5 (es) 1974-10-20
DE2365322B2 (de) 1977-02-24
KE2932A (en) 1979-03-30
AT353285B (de) 1979-11-12
CA1088931A (en) 1980-11-04
NO148998C (no) 1984-01-25
SE7700716L (sv) 1977-01-24
GB1456513A (en) 1976-11-24
YU288073A (en) 1982-02-28
ES433047A1 (es) 1976-11-01
FI60389B (fi) 1981-09-30
SE448992B (sv) 1987-03-30
DK144247C (da) 1982-07-12
DE2355540C2 (de) 1982-11-18
NO147836C (no) 1983-06-22
AT367034B (de) 1982-05-25
AR199966A1 (es) 1974-10-08
AT360672B (de) 1981-01-26
SU667141A3 (ru) 1979-06-05
FR2205335B1 (es) 1978-07-13
AR200585A1 (es) 1974-11-22
DD119411A5 (es) 1976-04-20
FR2283146B1 (es) 1981-06-19
YU270780A (en) 1982-06-18
CS182791B2 (en) 1978-05-31
DK144247B (da) 1982-01-25
ATA544576A (de) 1980-06-15
ATA936973A (de) 1981-10-15
FR2279729B1 (es) 1978-04-28
HK27979A (en) 1979-05-11
IN139384B (es) 1976-06-12
HK28079A (en) 1979-05-11
GB1456512A (en) 1976-11-24
IE39537B1 (en) 1978-11-08
AU470375B2 (en) 1976-03-11
NO149139B (no) 1983-11-14
JPS4993342A (es) 1974-09-05
DD118856A5 (es) 1976-03-20
DD117233A5 (es) 1976-01-05
PH13110A (en) 1979-11-28
SU745362A3 (ru) 1980-06-30
HK28179A (en) 1979-05-11
CS182793B2 (en) 1978-05-31
JPS5253841A (en) 1977-04-30
NO149139C (no) 1984-02-29
ATA544676A (de) 1979-04-15
SE7700718L (sv) 1977-01-24
SU584766A3 (ru) 1977-12-15
HU171819B (hu) 1978-03-28
FR2279729A1 (fr) 1976-02-20
YU37316B (en) 1984-08-31
ES433046A1 (es) 1977-06-16
DE2365322A1 (de) 1974-11-07
PH13272A (en) 1980-02-27
IE39537L (en) 1974-05-08
NL7315263A (es) 1974-05-10
SE431756B (sv) 1984-02-27
FR2283146A1 (fr) 1976-03-26
SE436278B (sv) 1984-11-26
YU36975B (en) 1984-08-31
SE7700717L (sv) 1977-01-24
ZA738554B (en) 1974-09-25
CA1085831A (en) 1980-09-16
JPS5416491B2 (es) 1979-06-22
NO147836B (no) 1983-03-14
KE2930A (en) 1979-03-30
HU172703B (hu) 1978-11-28
CH597176A5 (es) 1978-03-31
IL43589A0 (en) 1974-03-14
IL43589A (en) 1980-01-31
DE2355540A1 (de) 1974-05-22
AU6224773A (en) 1975-05-08
SE445111B (sv) 1986-06-02
MY7900246A (en) 1979-12-31
NO743493L (no) 1974-05-09
CS182794B2 (en) 1978-05-31
FI60389C (fi) 1982-01-11
NL164273C (nl) 1980-12-15
BE806995A (fr) 1974-05-07
GB1456514A (en) 1976-11-24
MY7900245A (en) 1979-12-31
CA1088930A (en) 1980-11-04
YU39715B (en) 1985-04-30

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Legal Events

Date Code Title Description
ST Notification of lapse