FR17C1011I1 - - Google Patents

Info

Publication number
FR17C1011I1
FR17C1011I1 FR17C1011C FR17C1011I1 FR 17C1011 I1 FR17C1011 I1 FR 17C1011I1 FR 17C1011 C FR17C1011 C FR 17C1011C FR 17C1011 I1 FR17C1011 I1 FR 17C1011I1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38691782&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR17C1011(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of FR17C1011I1 publication Critical patent/FR17C1011I1/fr
Application granted granted Critical
Publication of FR17C1011I2 publication Critical patent/FR17C1011I2/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR17C1011C 2007-08-06 2017-04-14 Inhibiteurs de proteasomes Active FR17C1011I2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/017440 WO2009020448A1 (en) 2007-08-06 2007-08-06 Proteasome inhibitors

Publications (2)

Publication Number Publication Date
FR17C1011I1 true FR17C1011I1 (xx) 2017-05-26
FR17C1011I2 FR17C1011I2 (fr) 2018-04-27

Family

ID=38691782

Family Applications (1)

Application Number Title Priority Date Filing Date
FR17C1011C Active FR17C1011I2 (fr) 2007-08-06 2017-04-14 Inhibiteurs de proteasomes

Country Status (33)

Country Link
EP (3) EP2527347A1 (xx)
JP (1) JP5261488B2 (xx)
KR (6) KR101831674B1 (xx)
CN (1) CN101772507B (xx)
AU (1) AU2007357338B2 (xx)
BR (1) BRPI0721905B8 (xx)
CA (1) CA2695082C (xx)
CY (2) CY1113386T1 (xx)
DK (1) DK2178888T3 (xx)
EA (1) EA028622B1 (xx)
EC (1) ECSP10010015A (xx)
ES (1) ES2390606T3 (xx)
FR (1) FR17C1011I2 (xx)
GE (1) GEP20125599B (xx)
HK (2) HK1143595A1 (xx)
HR (1) HRP20120745T1 (xx)
HU (1) HUS1700018I1 (xx)
IL (4) IL203641A (xx)
LT (1) LTC2178888I2 (xx)
LU (1) LUC00013I2 (xx)
MY (1) MY161991A (xx)
NL (1) NL300871I2 (xx)
NZ (1) NZ582693A (xx)
PH (1) PH12014500053A1 (xx)
PL (1) PL2178888T3 (xx)
PT (1) PT2178888E (xx)
RS (1) RS52435B (xx)
SG (1) SG10201508712QA (xx)
SI (1) SI2178888T1 (xx)
TN (1) TN2010000060A1 (xx)
UA (1) UA97536C2 (xx)
WO (1) WO2009020448A1 (xx)
ZA (1) ZA201000348B (xx)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
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US7576206B2 (en) 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
US7468383B2 (en) 2005-02-11 2008-12-23 Cephalon, Inc. Proteasome inhibitors and methods of using the same
DK2623113T3 (en) 2005-11-09 2017-07-17 Onyx Therapeutics Inc Enzyme inhibition compound
US7691852B2 (en) 2006-06-19 2010-04-06 Onyx Therapeutics, Inc. Compounds for enzyme inhibition
US7442830B1 (en) 2007-08-06 2008-10-28 Millenium Pharmaceuticals, Inc. Proteasome inhibitors
DK2207791T4 (da) 2007-10-04 2019-10-07 Onyx Therapeutics Inc Krystallinske peptidepoxyketon-proteasehæmmere og syntese af aminosyreketoepoxider
SG194349A1 (en) 2008-06-17 2013-11-29 Millennium Pharm Inc Boronate ester compounds and pharmaceutical compositions thereof
AR075090A1 (es) 2008-09-29 2011-03-09 Millennium Pharm Inc Derivados de acido 1-amino-2-ciclobutiletilboronico inhibidores de proteosoma,utiles como agentes anticancerigenos, y composiciones farmaceuticas que los comprenden.
ES2617560T3 (es) 2008-10-21 2017-06-19 Onyx Therapeutics, Inc. Combinación del inhibidor del proteasoma de epoxicetona peptídica carfilzomib con melfalán para su uso en el tratamiento del mieloma múltiple
TWI504598B (zh) 2009-03-20 2015-10-21 Onyx Therapeutics Inc 結晶性三肽環氧酮蛋白酶抑制劑
EP2498793B1 (en) 2009-11-13 2019-07-10 Onyx Therapeutics, Inc. Oprozomib for use in metastasis suppression
CA2785300A1 (en) 2009-12-22 2011-07-21 Cephalon, Inc. Proteasome inhibitors and processes for their preparation, purification and use
MA34133B1 (fr) 2010-03-01 2013-04-03 Onyx Therapeutics Inc Composes pour inhibiteurs de l'immunoproteasome
NZ602622A (en) 2010-03-31 2015-01-30 Millennium Pharm Inc Derivatives of 1-amino-2-cyclopropylethylboronic acid
WO2012177835A1 (en) * 2011-06-22 2012-12-27 Cephalon, Inc. Proteasome inhibitors and processes for their preparation, purification and use
PL2753334T3 (pl) * 2011-08-30 2022-12-12 Trustees Of Tufts College Aktywowane przez fap inhibitory proteasomu do leczenia guzów litych
SG10201605152SA (en) * 2011-12-22 2016-08-30 Ares Trading Sa Alpha-amino boronic acid derivatives, selective immunoproteasome inhibitors
WO2013112601A1 (en) * 2012-01-24 2013-08-01 Millennium Pharmaceuticals, Inc. Methods of treatment of cancer
CA2862320A1 (en) * 2012-01-24 2013-08-01 Millennium Pharmaceuticals, Inc. Method of treatment of nasopharyngeal cancer
EP2869820A4 (en) 2012-07-09 2016-02-17 Onyx Therapeutics Inc PRODRUGS OF PEPTIDEPOXIDE KETONE PROTEASE INHIBITORS
CN109096370B (zh) * 2012-07-26 2022-03-18 圣特莱国际公司 多肽环氧酮化合物
JP2013006855A (ja) * 2012-09-03 2013-01-10 Millennium Pharmaceuticals Inc プロテアソーム阻害剤
CN104822689B (zh) * 2012-12-03 2016-11-02 弗·哈夫曼-拉罗切有限公司 取代的三唑硼酸化合物
CN105705149A (zh) * 2013-10-03 2016-06-22 米伦纽姆医药公司 用于预防或治疗系统性红斑狼疮和/或狼疮性肾炎的方法
JP2017524652A (ja) 2014-05-20 2017-08-31 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 一次癌療法後に使用するためのホウ素含有プロテアソーム阻害剤
EP4180041A1 (en) 2014-08-07 2023-05-17 Mayo Foundation for Medical Education and Research Compounds and methods for treating cancer
MA41555A (fr) * 2015-02-17 2017-12-26 Millennium Pharm Inc Polythérapie pour le traitement du cancer
US10144761B2 (en) 2015-06-19 2018-12-04 Hanlin Scientific Inc. Chiral specific boron-containing compounds and their use in treating cancer or amyloidosis
CN106608883A (zh) * 2015-10-21 2017-05-03 北京大学 蛋白酶体抑制剂mln9708的合成方法
CN107400142B (zh) * 2016-05-19 2019-11-19 成都奥璟生物科技有限公司 一种硼酸和硼酸酯类化合物及其应用
CN106008572B (zh) * 2016-05-23 2018-08-17 成都千禧莱医药科技有限公司 一类二肽硼酸化合物及制备方法和用途
DK3472149T3 (da) 2016-06-21 2023-11-27 Orion Ophthalmology LLC Heterocykliske prolinamidderivater
JP7164521B2 (ja) 2016-06-21 2022-11-01 オリオン・オフサルモロジー・エルエルシー 炭素環式プロリンアミド誘導体
JP6802899B2 (ja) * 2016-07-25 2020-12-23 深▲セン▼市塔吉瑞生物医▲薬▼有限公司Ｓｈｅｎｚｈｅｎ ＴａｒｇｅｔＲｘ，Ｉｎｃ． 置換ボロン酸化合物、該化合物を含む医薬組成物およびその使用
WO2018133661A1 (zh) * 2017-01-23 2018-07-26 成都奥璟生物科技有限公司 一种新的硼酸衍生物及其药物组合物
EP3589659A4 (en) 2017-02-28 2021-03-24 Mayo Foundation for Medical Education and Research CANCER TREATMENT COMPOUNDS AND METHODS
CN108794516A (zh) * 2017-04-26 2018-11-13 上海时莱生物技术有限公司 硼酸和硼酸酯类化合物及其制备方法和用途
WO2019020099A1 (zh) * 2017-07-28 2019-01-31 成都地奥九泓制药厂 一种硼酸酯化合物、其合成方法及其用途
WO2019038406A1 (en) 2017-08-25 2019-02-28 Synthon B.V. PROCESS FOR THE PREPARATION OF IXAZOMIB OR ITS INTERMEDIATES
JP2018024694A (ja) * 2017-10-03 2018-02-15 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． プロテアソーム阻害剤
US11243207B2 (en) 2018-03-29 2022-02-08 Mayo Foundation For Medical Education And Research Assessing and treating cancer
CN110903310B (zh) * 2018-09-14 2022-11-22 成都奥璟生物科技有限公司 一种硼酸酯类药物及其用途
CN110357787A (zh) * 2019-08-02 2019-10-22 苏州艾和医药科技有限公司 依沙佐米合成工艺研究
EP4041246A4 (en) * 2019-10-07 2023-11-01 Cornell University ANTIMICROBIAL AND ANTIVIRAL EFFECTS OF ALKYL-BORONIC ACIDS C2-C7
CN110950897B (zh) * 2019-12-12 2021-05-28 山东大学 一种组蛋白去乙酰化酶、蛋白酶体双靶点抑制剂及其制备方法和应用

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US5250720A (en) 1987-06-05 1993-10-05 The Dupont Merck Pharmaceutical Company Intermediates for preparing peptide boronic acid inhibitors of trypsin-like proteases
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EP0315574A3 (de) 1987-11-05 1990-08-22 Hoechst Aktiengesellschaft Renin-Inhibitoren
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JP4416501B2 (ja) 2001-05-30 2010-02-17 ノバルティス アクチエンゲゼルシャフト ２−｛［ｎ−（２−アミノ−３−（ヘテロアリールまたはアリール）プロピオニル）−アミノアシル］−アミノ｝−アルキルボロン酸誘導体
US7576206B2 (en) * 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
US7223745B2 (en) 2003-08-14 2007-05-29 Cephalon, Inc. Proteasome inhibitors and methods of using the same
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Also Published As

Publication number Publication date
TN2010000060A1 (en) 2011-09-26
JP5261488B2 (ja) 2013-08-14
LUC00013I1 (xx) 2017-04-06
HUS1700018I1 (hu) 2017-05-29
KR20140042932A (ko) 2014-04-07
ES2390606T3 (es) 2012-11-14
KR20150010802A (ko) 2015-01-28
FR17C1011I2 (fr) 2018-04-27
BRPI0721905B8 (pt) 2021-05-25
HRP20120745T1 (hr) 2012-10-31
DK2178888T3 (da) 2012-10-01
IL242290A (en) 2017-12-31
IL242291A0 (en) 2015-11-30
EP2178888B1 (en) 2012-07-04
EP2178888A1 (en) 2010-04-28
PH12014500053B1 (en) 2015-03-30
IL203641A (en) 2015-11-30
EA201070247A1 (ru) 2010-06-30
CN101772507B (zh) 2012-12-12
RS52435B (en) 2013-02-28
GEP20125599B (en) 2012-08-10
EP2527347A1 (en) 2012-11-28
LTC2178888I2 (lt) 2018-03-12
AU2007357338A1 (en) 2009-02-12
NL300871I2 (nl) 2017-12-07
AU2007357338B2 (en) 2014-03-20
KR101474831B1 (ko) 2014-12-19
MY161991A (en) 2017-05-31
IL242292A0 (en) 2015-11-30
JP2010535759A (ja) 2010-11-25
WO2009020448A1 (en) 2009-02-12
PL2178888T3 (pl) 2012-11-30
EA028622B1 (ru) 2017-12-29
HK1182924A1 (zh) 2013-12-13
HK1143595A1 (en) 2011-01-07
LTPA2017010I1 (lt) 2017-05-10
KR20100059811A (ko) 2010-06-04
IL242290A0 (en) 2015-11-30
CA2695082A1 (en) 2009-02-12
BRPI0721905B1 (pt) 2020-11-17
CY1113386T1 (el) 2016-06-22
NZ582693A (en) 2012-01-12
SG10201508712QA (en) 2015-11-27
IL242291A (en) 2017-12-31
KR101831674B1 (ko) 2018-02-23
PH12014500053A1 (en) 2015-03-30
ECSP10010015A (es) 2010-04-30
BRPI0721905A2 (pt) 2014-02-25
KR20140042933A (ko) 2014-04-07
CN101772507A (zh) 2010-07-07
LUC00013I2 (xx) 2017-06-19
SI2178888T1 (sl) 2012-11-30
EP3210987A1 (en) 2017-08-30
UA97536C2 (xx) 2012-02-27
KR20160040735A (ko) 2016-04-14
CY2017016I1 (el) 2017-07-12
ZA201000348B (en) 2011-03-30
IL242292A (en) 2017-12-31
CA2695082C (en) 2015-07-28
PT2178888E (pt) 2012-10-04
CY2017016I2 (el) 2017-07-12
KR20170004031A (ko) 2017-01-10

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